LitCovid-sentences  

PMC:7077337 / 11676-19445 JSONTXT 15 Projects

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Id Subject Object Predicate Lexical cue
T76 0-2 Sentence denotes 5.
T77 3-21 Sentence denotes SARS and Pregnancy
T78 22-230 Sentence denotes Although there were relatively few documented cases of SARS occurring during pregnancy, several case reports and small clinical studies have described the clinical effects in pregnant women and their infants.
T79 231-420 Sentence denotes In reviewing these reports describing pregnant women with SARS in China it is possible, and perhaps even probable, that some of the same patients were included in more than one publication.
T80 421-621 Sentence denotes However, even if this is the case, there is no doubt that SARS coronavirus infection was found to be associated with severe maternal illness, maternal death, and spontaneous abortion [19,28,29,30,31].
T81 622-842 Sentence denotes Martha Anker, an expert in statistics formerly with the WHO and the University of Massachusetts, estimated that more than 100 cases of SARS-CoV infection occurred in pregnant women, which warrants closer inspection [27].
T82 843-986 Sentence denotes The clinical outcomes among pregnant women with SARS in Hong Kong were worse than those occurring in infected women who were not pregnant [32].
T83 987-1151 Sentence denotes Wong et al. [29] evaluated the obstetrical outcomes from a cohort of pregnant women who developed SARS in Hong Kong during the period of 1 February to 31 July 2003.
T84 1152-1344 Sentence denotes Four of the 7 women (57%) that presented during the 1st trimester sustained spontaneous miscarriages, likely a result of the hypoxia that was caused by SARS-related acute respiratory distress.
T85 1345-1434 Sentence denotes Among the 5 women who presented after 24 weeks gestation, 4 had preterm deliveries (80%).
T86 1435-1623 Sentence denotes A case-control study to determine the effects of SARS on pregnancy compared 10 pregnant and 40 non-pregnant women with the infection at the Princess Margaret Hospital in Hong Kong [27,33].
T87 1624-1782 Sentence denotes There were 3 deaths among the pregnant women with SARS (maternal mortality rate of 30%) and no deaths in the non-pregnant group of infected women (P = 0.006).
T88 1783-1964 Sentence denotes Renal failure (P = 0.006) and disseminated intravascular coagulopathy (P = 0.006) developed more frequently in pregnant SARS patients when compared with the non-pregnant SARS group.
T89 1965-2215 Sentence denotes Six pregnant women with SARS required admission to the intensive care unit (ICU) (60%) and 4 required endotracheal intubation (40%), compared with a 12.5% intubation rate (P = 0.065) and 17.5% ICU admission rate (P = 0.012) in the non-pregnant group.
T90 2216-2427 Sentence denotes Maxwell et al. [32] reported 7 pregnant women infected with SARS-CoV who were followed at a designated SARS unit—2 of the 7 died (CFR of 28%), and 4 (57%) required ICU hospitalization and mechanical ventilation.
T91 2428-2605 Sentence denotes In contrast, the mortality rate was less than 10% and mechanical ventilation rate less than 20% among non-pregnant, age-matched counterparts who were not infected with SARS-CoV.
T92 2606-2693 Sentence denotes Two women with SARS recovered and maintained their pregnancy but had infants with IUGR.
T93 2694-2790 Sentence denotes Among the live newborn infants, none had clinical or laboratory evidence for SARS-CoV infection.
T94 2791-2916 Sentence denotes The new mothers who had developed SARS were advised not to breastfeed to prevent possible vertical transmission of the virus.
T95 2917-3041 Sentence denotes Zhang et al. [34] described SARS-CoV infections in 5 primagravidas from Guangzhou, China at the height of the SARS epidemic.
T96 3042-3146 Sentence denotes Two of the mothers became infected in the 2nd trimester, and 3 developed infection in the 3rd trimester.
T97 3147-3252 Sentence denotes Two of the pregnant women had hospital-acquired SARS infections, and the other 3 were community-acquired.
T98 3253-3494 Sentence denotes All 5 pregnant women had fever and abnormal chest radiographs; 4 had cough; 4 developed hypoalbuminemia; 3 had elevated alanine aminotransferase levels (ALT), 3 had chills or rigor, 2 had decreased lymphocytes, and 2 had decreased platelets.
T99 3495-3591 Sentence denotes One pregnant woman required intensive care, but all recovered and there were no maternal deaths.
T100 3592-3663 Sentence denotes The 5 infants were clinically evaluated, and none had evidence of SARS.
T101 3664-3730 Sentence denotes Two pregnant women with SARS were reported from the United States.
T102 3731-3893 Sentence denotes In a detailed case report, Robertson et al. [35] described a 36-year-old pregnant woman with an intermittent cough of approximately 10 days duration and no fever.
T103 3894-4039 Sentence denotes While travelling in Hong Kong during the 2003 epidemic, she was exposed at her hotel to a person subsequently known to be infected with SARS-CoV.
T104 4040-4155 Sentence denotes At 19 weeks gestation she developed fever, anorexia, headache, increasing cough, weakness, and shortness of breath.
T105 4156-4228 Sentence denotes Upon returning to the United States she was hospitalized with pneumonia.
T106 4229-4327 Sentence denotes Obstetrical ultrasounds revealed a low-lying placenta (placenta previa) but were otherwise normal.
T107 4328-4425 Sentence denotes Following her discharge home and clinical recovery, she was found to have antibodies to SARS-CoV.
T108 4426-4556 Sentence denotes She underwent cesarean section at 38 weeks gestation because of the placenta previa and a healthy baby girl was delivered [35,36].
T109 4557-4602 Sentence denotes The placenta was interpreted as being normal.
T110 4603-4926 Sentence denotes At 130 days post-maternal illness, maternal serum and whole blood, swabs from maternal nasopharynx and rectum, post-delivery placenta, umbilical cord blood, amniotic fluid, and breast milk were collected for analysis—no viral RNA was detected in specimens tested by reverse transcriptase polymerase chain reaction (RT-PCR).
T111 4927-5089 Sentence denotes Antibodies to SARS-CoV were detected from maternal serum, umbilical cord blood, and breast milk by enzyme immunoassay (EIA) and indirect immunofluorescence assay.
T112 5090-5179 Sentence denotes No clinical specimens (except for cord blood) were available for testing from the infant.
T113 5180-5385 Sentence denotes The second case in the USA occurred in a 38-year-old woman who had travelled to Hong Kong at 7 weeks gestation where she was exposed to SARS-CoV in the same hotel as the aforementioned American woman [37].
T114 5386-5619 Sentence denotes Following her return to the United States, her husband developed the clinical onset of SARS, and 6 days later she became ill with fever, myalgia, chills, headache, coryza, and a productive cough with shortness of breath and wheezing.
T115 5620-5826 Sentence denotes Following her hospitalization for SARS she recovered, serum samples taken on days 28 and 64 post-onset of illness were positive for antibodies to SARS-CoV by enzyme immunoassay and immunofluorescent assays.
T116 5827-5918 Sentence denotes Her pregnancy continued and was unremarkable except for developing elevated glucose levels.
T117 5919-6065 Sentence denotes A cesarean section that was performed at 36 weeks gestation due to preterm rupture of membranes and fetal distress resulted in a healthy baby boy.
T118 6066-6229 Sentence denotes At the time of delivery, the mother’s serum samples were positive for antibodies to SARS-CoV, but samples taken of umbilical cord blood and placenta were negative.
T119 6230-6323 Sentence denotes Breast milk sampled 12 and 30 days after delivery were also negative for SARS-CoV antibodies.
T120 6324-6492 Sentence denotes Specimens evaluated from maternal blood, stool, and nasopharynx samples, as well as umbilical cord blood of the infant, were all negative for coronavirus RNA by RT-PCR.
T121 6493-6584 Sentence denotes Neonatal stool samples obtained on days-of-life 12 and 30 were also negative for viral RNA.
T122 6585-6797 Sentence denotes From Canada, Yudin et al. [38] reported a 33-year-old pregnant woman who was admitted to the hospital at 31 weeks gestation with a fever, dry cough, and abnormal chest radiograph demonstrating patchy infiltrates.
T123 6798-6864 Sentence denotes She had acquired SARS from contact with an infected family member.
T124 6865-7033 Sentence denotes Following a 21-day stay in the hospital, during which she did not require ventilatory support, her convalescent antibody titers were positive for coronavirus infection.
T125 7034-7120 Sentence denotes She had a normal labor and delivery and her newborn girl had no evidence of infection.
T126 7121-7383 Sentence denotes In a study of 5 liveborn neonates who were delivered to women infected with SARS-CoV during the Hong Kong epidemic, results from multiple tests—including serial RT-PCR assays, viral culture, and paired neonatal serological titers—were negative for SARS-CoV [39].
T127 7384-7487 Sentence denotes None of the 5 neonates developed any clinical signs or symptoms of respiratory infection or compromise.
T128 7488-7769 Sentence denotes Fortunately, there were no cases of vertical transmission identified among pregnant women infected with SARS-CoV during the 2002–2003 Asian epidemic [27,30,31,39,40], and with the exception of a small cluster of cases that recurred in late 2003, no new cases of SARS have occurred.