Id |
Subject |
Object |
Predicate |
Lexical cue |
T135 |
0-10 |
Sentence |
denotes |
Discussion |
T136 |
11-124 |
Sentence |
denotes |
Within 1 month of the 2019-nCoV disease outbreak, we rapidly developed molecular and serological detection tools. |
T137 |
125-299 |
Sentence |
denotes |
This is the first molecular and serological study on this virus after the initial identification of 2019-NCoV from 7 patients diagnosed with unidentified viral pneumonia [5]. |
T138 |
300-470 |
Sentence |
denotes |
We detected the virus in oral swabs, anal swabs and blood, thus infected patients can potentially shed this pathogen through respiratory, fecal–oral or body fluid routes. |
T139 |
471-605 |
Sentence |
denotes |
In addition, we successfully applied serology test a large population and showed which could greatly improved detection positive rate. |
T140 |
606-729 |
Sentence |
denotes |
We show that the current strategy for the detection of viral RNA in oral swabs used for 2019-nCoV diagnosis is not perfect. |
T141 |
730-825 |
Sentence |
denotes |
The virus may be present in anal swabs or blood of patients when oral swabs detection negative. |
T142 |
826-939 |
Sentence |
denotes |
In SARS-CoV and MERS-CoV infected patients, intestinal infection was observed at later stages of infection [7–9]. |
T143 |
940-1059 |
Sentence |
denotes |
However, patients infected with 2019-nCoV may harbour the virus in the intestine at the early or late stage of disease. |
T144 |
1060-1144 |
Sentence |
denotes |
It is also worth to note none of the patients with viremia blood had positive swabs. |
T145 |
1145-1278 |
Sentence |
denotes |
These patients would likely be considered as 2019-nCoV negative through routine surveillance, and thus pose a threat to other people. |
T146 |
1279-1408 |
Sentence |
denotes |
In contrast, we found viral antibodies in near all patients, indicating serology should be considered for 2019-nCoV epidemiology. |
T147 |
1409-1528 |
Sentence |
denotes |
A possible shift from oral positive during early infection to anal swab positive during late infection can be observed. |
T148 |
1529-1675 |
Sentence |
denotes |
This observation implied that we cannot discharge a patient purely based on oral swabs negative, who may still shed the virus by oral–fecal route. |
T149 |
1676-1834 |
Sentence |
denotes |
Above all, we strongly suggest using viral IgM and IgG serological test to confirm an infection, considering the unreliable results from oral swabs detection. |
T150 |
1835-1937 |
Sentence |
denotes |
In summary, we provide a cautionary warning that 2019-nCoV may be transmitted through multiple routes. |
T151 |
1938-2026 |
Sentence |
denotes |
Both molecular and serological tests are needed to definitively confirm a virus carrier. |