LitCovid-sentences  

PMC:7036338 / 6945-9311 JSONTXT 11 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T48 0-136 Sentence denotes This study presents the viral load kinetics of the first two confirmed patients in Korea in whom distinct viral load kinetics are shown.
T49 137-385 Sentence denotes Although the viral load and CXR findings in these two patients may not represent the whole spectrum of SARS-CoV-2 illness, our report will provide many important findings and opportunity to understand this newly discovered virus infection in human.
T50 386-559 Sentence denotes In Patient 1, we observed one example of moderate disease (shortness of breath and oxygen requirement up to 10 L/min) with corresponding radiograph findings and viral loads.
T51 560-692 Sentence denotes We could observe her clinical presentation from day 2 of symptom onset and the whole clinical picture was captured with viral loads.
T52 693-756 Sentence denotes There are several important implications from this observation.
T53 757-1017 Sentence denotes First, unlike SARS-CoV infection,8 we found that viral load was highest during the early phase of the illness (3–5 days from first symptom onset, fever and myalgia were the only symptoms in Patient 1) and continued to decrease until the end of the second week.
T54 1018-1202 Sentence denotes While she developed cough as well as shortness of breath and infiltration appeared on CXR at the end of first week of illness, the viral load already started to decrease at this phase.
T55 1203-1360 Sentence denotes This may have a very important implication to determine the optimal time point for antiviral treatment intervention to prevent progression to severe disease.
T56 1361-1539 Sentence denotes Second, the virus was detected from LRT specimens even before the development of LRT symptoms (cough, shortness of breath, and oxygen requirement) or visible infiltration on CXR.
T57 1540-1746 Sentence denotes This may suggest that although the patient does not complain of any LRT symptoms, the virus is already there and causing insidious pathology, ultimately leading to LRT symptoms and chest infiltration later.
T58 1747-1870 Sentence denotes However, the viral load starts to decrease in both URT and LRT specimens at the same time, which may puzzle the clinicians.
T59 1871-2011 Sentence denotes Third, unlike in MERS-CoV revealing higher concentration of virus in LRT specimens,9 viral loads were similar in both URT and LRT specimens.
T60 2012-2189 Sentence denotes Fourth, low concentration of genetic materials, especially E gene, was detected in urine and stool from the end of the first week until the patient recovered from the infection.
T61 2190-2267 Sentence denotes However, rRT-PCR results did not meet the criteria for SARS-CoV-2 positivity.
T62 2268-2366 Sentence denotes Further studies need to be performed in non-respiratory specimens such as urine and stool samples.