PMC:6988269 / 1363-3933 JSONTXT 12 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T15 0-12 Sentence denotes Introduction
T16 13-203 Sentence denotes According to the World Health Organization (WHO), the WHO China Country Office was informed of cases of pneumonia of unknown aetiology in Wuhan City, Hubei Province, on 31 December 2019 [1].
T17 204-335 Sentence denotes A novel coronavirus currently termed 2019-nCoV was officially announced as the causative agent by Chinese authorities on 7 January.
T18 336-684 Sentence denotes A viral genome sequence was released for immediate public health support via the community online resource virological.org on 10 January (Wuhan-Hu-1, GenBank accession number MN908947 [2]), followed by four other genomes deposited on 12 January in the viral sequence database curated by the Global Initiative on Sharing All Influenza Data (GISAID).
T19 685-924 Sentence denotes The genome sequences suggest presence of a virus closely related to the members of a viral species termed severe acute respiratory syndrome (SARS)-related CoV, a species defined by the agent of the 2002/03 outbreak of SARS in humans [3,4].
T20 925-1033 Sentence denotes The species also comprises a large number of viruses mostly detected in rhinolophid bats in Asia and Europe.
T21 1034-1124 Sentence denotes As at 20 January 2019, 282 laboratory-confirmed human cases have been notified to WHO [5].
T22 1125-1272 Sentence denotes Confirmed cases in travellers from Wuhan were announced on 13 and 17 January in Thailand as well as on 15 January in Japan and 19 January in Korea.
T23 1273-1435 Sentence denotes The extent of human-to-human transmission of 2019-nCoV is unclear at the time of writing of this report but there is evidence of some human-to-human transmission.
T24 1436-1541 Sentence denotes Among the foremost priorities to facilitate public health interventions is reliable laboratory diagnosis.
T25 1542-1655 Sentence denotes In acute respiratory infection, RT-PCR is routinely used to detect causative viruses from respiratory secretions.
T26 1656-1907 Sentence denotes We have previously demonstrated the feasibility of introducing robust detection technology based on real-time RT-PCR in public health laboratories during international health emergencies by coordination between public and academic laboratories [6-12].
T27 1908-2053 Sentence denotes In all of these situations, virus isolates were available as the primary substrate for establishing and controlling assays and assay performance.
T28 2054-2215 Sentence denotes In the present case of 2019-nCoV, virus isolates or samples from infected patients have so far not become available to the international public health community.
T29 2216-2421 Sentence denotes We report here on the establishment and validation of a diagnostic workflow for 2019-nCoV screening and specific confirmation, designed in absence of available virus isolates or original patient specimens.
T30 2422-2570 Sentence denotes Design and validation were enabled by the close genetic relatedness to the 2003 SARS-CoV, and aided by the use of synthetic nucleic acid technology.