Id |
Subject |
Object |
Predicate |
Lexical cue |
TextSentencer_T1 |
0-83 |
Sentence |
denotes |
Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China. |
TextSentencer_T2 |
84-95 |
Sentence |
denotes |
BACKGROUND: |
TextSentencer_T3 |
96-227 |
Sentence |
denotes |
A recent cluster of pneumonia cases in Wuhan, China, was caused by a novel betacoronavirus, the 2019 novel coronavirus (2019-nCoV). |
TextSentencer_T4 |
228-368 |
Sentence |
denotes |
We report the epidemiological, clinical, laboratory, and radiological characteristics and treatment and clinical outcomes of these patients. |
TextSentencer_T5 |
369-377 |
Sentence |
denotes |
METHODS: |
TextSentencer_T6 |
378-464 |
Sentence |
denotes |
All patients with suspected 2019-nCoV were admitted to a designated hospital in Wuhan. |
TextSentencer_T7 |
465-619 |
Sentence |
denotes |
We prospectively collected and analysed data on patients with laboratory-confirmed 2019-nCoV infection by real-time RT-PCR and next-generation sequencing. |
TextSentencer_T8 |
620-806 |
Sentence |
denotes |
Data were obtained with standardised data collection forms shared by WHO and the International Severe Acute Respiratory and Emerging Infection Consortium from electronic medical records. |
TextSentencer_T9 |
807-924 |
Sentence |
denotes |
Researchers also directly communicated with patients or their families to ascertain epidemiological and symptom data. |
TextSentencer_T10 |
925-1047 |
Sentence |
denotes |
Outcomes were also compared between patients who had been admitted to the intensive care unit (ICU) and those who had not. |
TextSentencer_T11 |
1048-1057 |
Sentence |
denotes |
FINDINGS: |
TextSentencer_T12 |
1058-1175 |
Sentence |
denotes |
By Jan 2, 2020, 41 admitted hospital patients had been identified as having laboratory-confirmed 2019-nCoV infection. |
TextSentencer_T13 |
1176-1383 |
Sentence |
denotes |
Most of the infected patients were men (30 [73%] of 41); less than half had underlying diseases (13 [32%]), including diabetes (eight [20%]), hypertension (six [15%]), and cardiovascular disease (six [15%]). |
TextSentencer_T14 |
1384-1426 |
Sentence |
denotes |
Median age was 49·0 years (IQR 41·0-58·0). |
TextSentencer_T15 |
1427-1493 |
Sentence |
denotes |
27 (66%) of 41 patients had been exposed to Huanan seafood market. |
TextSentencer_T16 |
1494-1523 |
Sentence |
denotes |
One family cluster was found. |
TextSentencer_T17 |
1524-1803 |
Sentence |
denotes |
Common symptoms at onset of illness were fever (40 [98%] of 41 patients), cough (31 [76%]), and myalgia or fatigue (18 [44%]); less common symptoms were sputum production (11 [28%] of 39), headache (three [8%] of 38), haemoptysis (two [5%] of 39), and diarrhoea (one [3%] of 38). |
TextSentencer_T18 |
1804-1919 |
Sentence |
denotes |
Dyspnoea developed in 22 (55%) of 40 patients (median time from illness onset to dyspnoea 8·0 days [IQR 5·0-13·0]). |
TextSentencer_T19 |
1920-1960 |
Sentence |
denotes |
26 (63%) of 41 patients had lymphopenia. |
TextSentencer_T20 |
1961-2026 |
Sentence |
denotes |
All 41 patients had pneumonia with abnormal findings on chest CT. |
TextSentencer_T21 |
2027-2191 |
Sentence |
denotes |
Complications included acute respiratory distress syndrome (12 [29%]), RNAaemia (six [15%]), acute cardiac injury (five [12%]) and secondary infection (four [10%]). |
TextSentencer_T22 |
2192-2253 |
Sentence |
denotes |
13 (32%) patients were admitted to an ICU and six (15%) died. |
TextSentencer_T23 |
2254-2377 |
Sentence |
denotes |
Compared with non-ICU patients, ICU patients had higher plasma levels of IL2, IL7, IL10, GSCF, IP10, MCP1, MIP1A, and TNFα. |
TextSentencer_T24 |
2378-2393 |
Sentence |
denotes |
INTERPRETATION: |
TextSentencer_T25 |
2394-2578 |
Sentence |
denotes |
The 2019-nCoV infection caused clusters of severe respiratory illness similar to severe acute respiratory syndrome coronavirus and was associated with ICU admission and high mortality. |
TextSentencer_T26 |
2579-2735 |
Sentence |
denotes |
Major gaps in our knowledge of the origin, epidemiology, duration of human transmission, and clinical spectrum of disease need fulfilment by future studies. |
TextSentencer_T27 |
2736-2744 |
Sentence |
denotes |
FUNDING: |
TextSentencer_T28 |
2745-2920 |
Sentence |
denotes |
Ministry of Science and Technology, Chinese Academy of Medical Sciences, National Natural Science Foundation of China, and Beijing Municipal Science and Technology Commission. |