Id |
Subject |
Object |
Predicate |
Lexical cue |
T157 |
0-14 |
Sentence |
denotes |
5.2 Rational: |
T158 |
15-83 |
Sentence |
denotes |
Recombinant type I IFN can effectively inhibit SARS-CoV2 replication |
T159 |
84-272 |
Sentence |
denotes |
In 24–48 h after infection, SARS-CoV2 replication reaches titer that causes the cytopathic effect in Vero E6 cells, which express ACE2 and thus are susceptible to SARS-CoV2 infection [25]. |
T160 |
273-339 |
Sentence |
denotes |
It is similar to the viral replication kinetics for SARS-CoV [25]. |
T161 |
340-470 |
Sentence |
denotes |
Pretreatment with recombinant type I IFN could effectively inhibit SARS-CoV2 replication at both 24 and 48 h after infection [25]. |
T162 |
471-560 |
Sentence |
denotes |
For SARS-CoV, such an effect was present at 24 h but absent at 48 h after infection [25]. |
T163 |
561-747 |
Sentence |
denotes |
The difference between SARS-CoV2 and SARS-CoV in response to type I IFN treatment may be due to differences in structural proteins of these viruses, including NSP3, ORF3b, and ORF6 [25]. |