PMC:7205724 / 19731-20478 JSONTXT 19 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T157 0-14 Sentence denotes 5.2 Rational:
T158 15-83 Sentence denotes Recombinant type I IFN can effectively inhibit SARS-CoV2 replication
T159 84-272 Sentence denotes In 24–48 h after infection, SARS-CoV2 replication reaches titer that causes the cytopathic effect in Vero E6 cells, which express ACE2 and thus are susceptible to SARS-CoV2 infection [25].
T160 273-339 Sentence denotes It is similar to the viral replication kinetics for SARS-CoV [25].
T161 340-470 Sentence denotes Pretreatment with recombinant type I IFN could effectively inhibit SARS-CoV2 replication at both 24 and 48 h after infection [25].
T162 471-560 Sentence denotes For SARS-CoV, such an effect was present at 24 h but absent at 48 h after infection [25].
T163 561-747 Sentence denotes The difference between SARS-CoV2 and SARS-CoV in response to type I IFN treatment may be due to differences in structural proteins of these viruses, including NSP3, ORF3b, and ORF6 [25].