| Id |
Subject |
Object |
Predicate |
Lexical cue |
| tok1 |
0-10 |
NNP |
denotes |
Structure- |
| tok2 |
10-16 |
NNP |
denotes |
Guided |
| tok3 |
17-28 |
NNP |
denotes |
Mutagenesis |
| tok4 |
29-35 |
NNP |
denotes |
Alters |
| tok5 |
36-52 |
NNP |
denotes |
Deubiquitinating |
| tok6 |
53-61 |
NN |
denotes |
Activity |
| tok7 |
62-65 |
CC |
denotes |
and |
| tok8 |
66-76 |
NNP |
denotes |
Attenuates |
| tok9 |
77-89 |
NNP |
denotes |
Pathogenesis |
| tok10 |
90-92 |
IN |
denotes |
of |
| tok11 |
93-94 |
DT |
denotes |
a |
| tok12 |
95-101 |
NNP |
denotes |
Murine |
| tok13 |
102-113 |
NNP |
denotes |
Coronavirus |
| tok14 |
113-114 |
. |
denotes |
. |
| tok15 |
115-128 |
NNP |
denotes |
Coronaviruses |
| tok16 |
129-136 |
VB |
denotes |
express |
| event21 |
129-136 |
OCCURRENCE |
denotes |
express |
| tok17 |
137-138 |
DT |
denotes |
a |
| tok18 |
139-154 |
NN |
denotes |
multifunctional |
| tok19 |
155-166 |
JJ |
denotes |
papain-like |
| tok20 |
167-175 |
NN |
denotes |
protease |
| tok21 |
175-176 |
, |
denotes |
, |
| tok22 |
177-183 |
VBD |
denotes |
termed |
| tok23 |
184-187 |
NNP |
denotes |
PLP |
| tok24 |
187-188 |
CD |
denotes |
2 |
| tok25 |
188-189 |
. |
denotes |
. |
| tok26 |
190-193 |
NNP |
denotes |
PLP |
| tok27 |
193-194 |
CD |
denotes |
2 |
| tok28 |
195-199 |
NNS |
denotes |
acts |
| tok29 |
200-202 |
IN |
denotes |
as |
| lookup1 |
200-202 |
country_code |
denotes |
as |
| tok30 |
203-204 |
DT |
denotes |
a |
| tok31 |
205-213 |
NN |
denotes |
protease |
| tok32 |
214-218 |
IN |
denotes |
that |
| tok33 |
219-226 |
NNS |
denotes |
cleaves |
| tok34 |
227-230 |
DT |
denotes |
the |
| tok35 |
231-236 |
JJ |
denotes |
viral |
| tok36 |
237-246 |
NN |
denotes |
replicase |
| tok37 |
247-258 |
NN |
denotes |
polyprotein |
| tok38 |
258-259 |
, |
denotes |
, |
| tok39 |
260-263 |
CC |
denotes |
and |
| tok40 |
264-265 |
DT |
denotes |
a |
| tok41 |
266-282 |
VBG |
denotes |
deubiquitinating |
| event18 |
266-282 |
OCCURRENCE |
denotes |
deubiquitinating |
| tok42 |
283-284 |
( |
denotes |
( |
| tok43 |
284-287 |
NNP |
denotes |
DUB |
| tok44 |
287-288 |
) |
denotes |
) |
| tok45 |
289-295 |
NN |
denotes |
enzyme |
| tok46 |
296-301 |
WDT |
denotes |
which |
| tok47 |
302-309 |
VBZ |
denotes |
removes |
| tok48 |
310-319 |
NN |
denotes |
ubiquitin |
| tok49 |
320-328 |
NNS |
denotes |
moieties |
| tok50 |
329-333 |
IN |
denotes |
from |
| tok51 |
334-354 |
JJ |
denotes |
ubiquitin-conjugated |
| tok52 |
355-363 |
NNS |
denotes |
proteins |
| tok53 |
363-364 |
. |
denotes |
. |
| tok54 |
365-373 |
JJ |
denotes |
Previous |
| tok55 |
374-376 |
IN |
denotes |
in |
| lookup2 |
374-376 |
country_code |
denotes |
in |
| tok56 |
377-382 |
NN |
denotes |
vitro |
| tok57 |
383-390 |
NNS |
denotes |
studies |
| tok58 |
391-401 |
VBN |
denotes |
implicated |
| tok59 |
402-405 |
NNP |
denotes |
PLP |
| tok60 |
405-406 |
CD |
denotes |
2 |
| tok61 |
407-410 |
NNP |
denotes |
DUB |
| tok62 |
411-419 |
NN |
denotes |
activity |
| tok63 |
420-422 |
IN |
denotes |
as |
| lookup3 |
420-422 |
country_code |
denotes |
as |
| tok64 |
423-424 |
DT |
denotes |
a |
| tok65 |
425-433 |
JJ |
denotes |
negative |
| tok66 |
434-443 |
NN |
denotes |
regulator |
| lookup4 |
434-443 |
jobtitle |
denotes |
regulator |
| tok67 |
444-446 |
IN |
denotes |
of |
| tok68 |
447-450 |
DT |
denotes |
the |
| tok69 |
451-455 |
NN |
denotes |
host |
| tok70 |
456-466 |
NN |
denotes |
interferon |
| tok71 |
467-468 |
( |
denotes |
( |
| tok72 |
468-471 |
NNP |
denotes |
IFN |
| tok73 |
471-472 |
) |
denotes |
) |
| tok74 |
473-481 |
NN |
denotes |
response |
| tok75 |
481-482 |
, |
denotes |
, |
| tok76 |
483-486 |
CC |
denotes |
but |
| tok77 |
487-490 |
DT |
denotes |
the |
| tok78 |
491-495 |
NN |
denotes |
role |
| tok79 |
496-498 |
IN |
denotes |
of |
| tok80 |
499-502 |
NNP |
denotes |
DUB |
| tok81 |
503-511 |
NN |
denotes |
activity |
| tok82 |
512-518 |
IN |
denotes |
during |
| tok83 |
519-524 |
NN |
denotes |
virus |
| tok84 |
525-534 |
NN |
denotes |
infection |
| tok85 |
535-538 |
VBD |
denotes |
was |
| tok86 |
539-546 |
JJ |
denotes |
unknown |
| tok87 |
546-547 |
. |
denotes |
. |
| tok88 |
548-552 |
RB |
denotes |
Here |
| lookup5 |
548-552 |
stop |
denotes |
Here |
| tok89 |
552-553 |
, |
denotes |
, |
| tok90 |
554-556 |
PRP |
denotes |
we |
| tok91 |
557-561 |
VBD |
denotes |
used |
| event31 |
557-561 |
OCCURRENCE |
denotes |
used |
| tok92 |
562-564 |
NNP |
denotes |
X- |
| tok93 |
564-567 |
NN |
denotes |
ray |
| lookup6 |
564-567 |
person_first |
denotes |
ray |
| tok94 |
568-584 |
JJ |
denotes |
structure-guided |
| tok95 |
585-596 |
NNS |
denotes |
mutagenesis |
| tok96 |
597-600 |
CC |
denotes |
and |
| tok97 |
601-611 |
JJ |
denotes |
functional |
| tok98 |
612-619 |
NNS |
denotes |
studies |
| tok99 |
620-622 |
TO |
denotes |
to |
| lookup7 |
620-622 |
country_code |
denotes |
to |
| tok100 |
623-631 |
VB |
denotes |
identify |
| event1 |
623-631 |
OCCURRENCE |
denotes |
identify |
| tok101 |
632-637 |
JJ |
denotes |
amino |
| tok102 |
638-642 |
NN |
denotes |
acid |
| tok103 |
643-656 |
NNS |
denotes |
substitutions |
| tok104 |
657-663 |
IN |
denotes |
within |
| tok105 |
664-667 |
DT |
denotes |
the |
| tok106 |
668-685 |
JJ |
denotes |
ubiquitin-binding |
| tok107 |
686-693 |
NN |
denotes |
surface |
| tok108 |
694-696 |
IN |
denotes |
of |
| tok109 |
697-700 |
NNP |
denotes |
PLP |
| tok110 |
700-701 |
CD |
denotes |
2 |
| tok111 |
702-706 |
WDT |
denotes |
that |
| tok112 |
707-714 |
VBD |
denotes |
reduced |
| event12 |
707-714 |
OCCURRENCE |
denotes |
reduced |
| tok113 |
715-718 |
NNP |
denotes |
DUB |
| tok114 |
719-727 |
NN |
denotes |
activity |
| tok115 |
728-735 |
IN |
denotes |
without |
| tok116 |
736-745 |
VBG |
denotes |
affecting |
| event4 |
736-745 |
OCCURRENCE |
denotes |
affecting |
| tok117 |
746-757 |
NN |
denotes |
polyprotein |
| tok118 |
758-768 |
NN |
denotes |
processing |
| tok119 |
769-777 |
NN |
denotes |
activity |
| tok120 |
777-778 |
. |
denotes |
. |
| tok121 |
779-781 |
PRP |
denotes |
We |
| lookup8 |
779-781 |
stop |
denotes |
We |
| tok122 |
782-792 |
VBN |
denotes |
engineered |
| event26 |
782-792 |
OCCURRENCE |
denotes |
engineered |
| tok123 |
793-794 |
DT |
denotes |
a |
| tok124 |
795-798 |
NNP |
denotes |
DUB |
| tok125 |
799-807 |
NN |
denotes |
mutation |
| tok126 |
808-809 |
( |
denotes |
( |
| tok127 |
809-812 |
NNP |
denotes |
Asp |
| tok128 |
812-816 |
CD |
denotes |
1772 |
| tok129 |
817-819 |
TO |
denotes |
to |
| lookup9 |
817-819 |
country_code |
denotes |
to |
| tok130 |
820-823 |
NNP |
denotes |
Ala |
| lookup10 |
820-823 |
person_first |
denotes |
Ala |
| tok131 |
823-824 |
) |
denotes |
) |
| tok132 |
825-829 |
IN |
denotes |
into |
| tok133 |
830-831 |
DT |
denotes |
a |
| tok134 |
832-838 |
NN |
denotes |
murine |
| tok135 |
839-850 |
JJ |
denotes |
coronavirus |
| tok136 |
851-854 |
CC |
denotes |
and |
| tok137 |
855-864 |
VBD |
denotes |
evaluated |
| event27 |
855-864 |
OCCURRENCE |
denotes |
evaluated |
| tok138 |
865-868 |
DT |
denotes |
the |
| tok139 |
869-880 |
NN |
denotes |
replication |
| tok140 |
881-884 |
CC |
denotes |
and |
| tok141 |
885-897 |
NNS |
denotes |
pathogenesis |
| tok142 |
898-900 |
IN |
denotes |
of |
| tok143 |
901-904 |
DT |
denotes |
the |
| tok144 |
905-908 |
NNP |
denotes |
DUB |
| tok145 |
909-915 |
JJ |
denotes |
mutant |
| tok146 |
916-921 |
NN |
denotes |
virus |
| tok147 |
922-923 |
( |
denotes |
( |
| tok148 |
923-929 |
NNP |
denotes |
DUBmut |
| tok149 |
929-930 |
) |
denotes |
) |
| tok150 |
931-933 |
IN |
denotes |
in |
| lookup11 |
931-933 |
country_code |
denotes |
in |
| tok151 |
934-942 |
JJ |
denotes |
cultured |
| tok152 |
943-954 |
NNS |
denotes |
macrophages |
| tok153 |
955-958 |
CC |
denotes |
and |
| tok154 |
959-961 |
IN |
denotes |
in |
| lookup12 |
959-961 |
country_code |
denotes |
in |
| tok155 |
962-966 |
NNS |
denotes |
mice |
| tok156 |
966-967 |
. |
denotes |
. |
| tok157 |
968-970 |
PRP |
denotes |
We |
| lookup13 |
968-970 |
stop |
denotes |
We |
| tok158 |
971-976 |
VBD |
denotes |
found |
| event6 |
971-976 |
OCCURRENCE |
denotes |
found |
| tok159 |
977-981 |
IN |
denotes |
that |
| tok160 |
982-985 |
DT |
denotes |
the |
| tok161 |
986-992 |
NNP |
denotes |
DUBmut |
| tok162 |
993-998 |
NN |
denotes |
virus |
| tok163 |
999-1009 |
NNS |
denotes |
replicates |
| tok164 |
1010-1019 |
RB |
denotes |
similarly |
| tok165 |
1020-1022 |
IN |
denotes |
as |
| lookup14 |
1020-1022 |
country_code |
denotes |
as |
| tok166 |
1023-1026 |
DT |
denotes |
the |
| tok167 |
1027-1036 |
JJ |
denotes |
wild-type |
| tok168 |
1037-1042 |
NN |
denotes |
virus |
| tok169 |
1043-1045 |
IN |
denotes |
in |
| lookup15 |
1043-1045 |
country_code |
denotes |
in |
| tok170 |
1046-1054 |
JJ |
denotes |
cultured |
| tok171 |
1055-1060 |
NNS |
denotes |
cells |
| tok172 |
1060-1061 |
, |
denotes |
, |
| tok173 |
1062-1065 |
CC |
denotes |
but |
| tok174 |
1066-1069 |
DT |
denotes |
the |
| tok175 |
1070-1076 |
NNP |
denotes |
DUBmut |
| tok176 |
1077-1082 |
NN |
denotes |
virus |
| tok177 |
1083-1092 |
NNS |
denotes |
activates |
| tok178 |
1093-1095 |
DT |
denotes |
an |
| lookup16 |
1093-1095 |
country_code |
denotes |
an |
| tok179 |
1096-1099 |
NNP |
denotes |
IFN |
| tok180 |
1100-1108 |
NN |
denotes |
response |
| tok181 |
1109-1111 |
IN |
denotes |
at |
| lookup17 |
1109-1111 |
country_code |
denotes |
at |
| tok182 |
1112-1119 |
JJR |
denotes |
earlier |
| tok183 |
1120-1125 |
NNS |
denotes |
times |
| tok184 |
1126-1134 |
VBN |
denotes |
compared |
| event32 |
1126-1134 |
I_ACTION |
denotes |
compared |
| tok185 |
1135-1137 |
TO |
denotes |
to |
| lookup18 |
1135-1137 |
country_code |
denotes |
to |
| tok186 |
1138-1141 |
DT |
denotes |
the |
| tok187 |
1142-1151 |
JJ |
denotes |
wild-type |
| tok188 |
1152-1157 |
NN |
denotes |
virus |
| tok189 |
1158-1167 |
NN |
denotes |
infection |
| tok190 |
1168-1170 |
IN |
denotes |
in |
| lookup19 |
1168-1170 |
country_code |
denotes |
in |
| tok191 |
1171-1182 |
NNS |
denotes |
macrophages |
| tok192 |
1182-1183 |
, |
denotes |
, |
| tok193 |
1184-1194 |
JJ |
denotes |
consistent |
| tok194 |
1195-1199 |
IN |
denotes |
with |
| tok195 |
1200-1203 |
NNP |
denotes |
DUB |
| tok196 |
1204-1212 |
NN |
denotes |
activity |
| tok197 |
1213-1223 |
RB |
denotes |
negatively |
| tok198 |
1224-1234 |
VBG |
denotes |
regulating |
| event34 |
1224-1234 |
OCCURRENCE |
denotes |
regulating |
| tok199 |
1235-1238 |
DT |
denotes |
the |
| tok200 |
1239-1242 |
NNP |
denotes |
IFN |
| tok201 |
1243-1251 |
NN |
denotes |
response |
| tok202 |
1251-1252 |
. |
denotes |
. |
| tok203 |
1253-1255 |
PRP |
denotes |
We |
| lookup20 |
1253-1255 |
stop |
denotes |
We |
| tok204 |
1256-1264 |
VBD |
denotes |
compared |
| tok205 |
1265-1268 |
DT |
denotes |
the |
| tok206 |
1269-1281 |
NNS |
denotes |
pathogenesis |
| tok207 |
1282-1284 |
IN |
denotes |
of |
| tok208 |
1285-1288 |
DT |
denotes |
the |
| tok209 |
1289-1295 |
NNP |
denotes |
DUBmut |
| tok210 |
1296-1301 |
NN |
denotes |
virus |
| tok211 |
1302-1304 |
TO |
denotes |
to |
| lookup21 |
1302-1304 |
country_code |
denotes |
to |
| tok212 |
1305-1308 |
DT |
denotes |
the |
| tok213 |
1309-1318 |
JJ |
denotes |
wild-type |
| tok214 |
1319-1324 |
NN |
denotes |
virus |
| tok215 |
1325-1328 |
CC |
denotes |
and |
| tok216 |
1329-1334 |
VBD |
denotes |
found |
| event30 |
1329-1334 |
OCCURRENCE |
denotes |
found |
| tok217 |
1335-1339 |
IN |
denotes |
that |
| tok218 |
1340-1343 |
DT |
denotes |
the |
| tok219 |
1344-1359 |
NNP |
denotes |
DUBmut-infected |
| tok220 |
1360-1364 |
NNS |
denotes |
mice |
| tok221 |
1365-1368 |
VBD |
denotes |
had |
| event2 |
1365-1368 |
STATE |
denotes |
had |
| tok222 |
1369-1370 |
DT |
denotes |
a |
| tok223 |
1371-1384 |
RB |
denotes |
statistically |
| tok224 |
1385-1396 |
JJ |
denotes |
significant |
| tok225 |
1397-1406 |
NN |
denotes |
reduction |
| tok226 |
1407-1408 |
( |
denotes |
( |
| tok227 |
1408-1409 |
NN |
denotes |
p |
| lookup22 |
1408-1409 |
currency_unit |
denotes |
p |
| tok228 |
1409-1410 |
NN |
denotes |
< |
| tok229 |
1410-1411 |
CD |
denotes |
0 |
| tok230 |
1411-1412 |
. |
denotes |
. |
| tok231 |
1412-1414 |
CD |
denotes |
05 |
| tok232 |
1414-1415 |
) |
denotes |
) |
| tok233 |
1416-1418 |
IN |
denotes |
in |
| lookup23 |
1416-1418 |
country_code |
denotes |
in |
| tok234 |
1419-1424 |
JJ |
denotes |
viral |
| tok235 |
1425-1430 |
NN |
denotes |
titer |
| tok236 |
1431-1433 |
IN |
denotes |
in |
| lookup24 |
1431-1433 |
country_code |
denotes |
in |
| tok237 |
1434-1440 |
NNS |
denotes |
livers |
| tok238 |
1441-1444 |
CC |
denotes |
and |
| tok239 |
1445-1452 |
NNS |
denotes |
spleens |
| tok240 |
1453-1455 |
IN |
denotes |
at |
| lookup25 |
1453-1455 |
country_code |
denotes |
at |
| tok241 |
1456-1459 |
NN |
denotes |
day |
| lookup26 |
1456-1459 |
date_unit |
denotes |
day |
| tok242 |
1460-1461 |
CD |
denotes |
5 |
| tok243 |
1462-1476 |
JJ |
denotes |
post-infection |
| tok244 |
1476-1477 |
, |
denotes |
, |
| tok245 |
1478-1484 |
IN |
denotes |
albeit |
| tok246 |
1485-1489 |
DT |
denotes |
both |
| tok247 |
1490-1499 |
JJ |
denotes |
wild-type |
| tok248 |
1500-1503 |
CC |
denotes |
and |
| tok249 |
1504-1510 |
NNP |
denotes |
DUBmut |
| tok250 |
1511-1516 |
NN |
denotes |
virus |
| tok251 |
1517-1527 |
NNS |
denotes |
infections |
| tok252 |
1528-1536 |
VBD |
denotes |
resulted |
| event19 |
1528-1536 |
OCCURRENCE |
denotes |
resulted |
| tok253 |
1537-1539 |
IN |
denotes |
in |
| lookup27 |
1537-1539 |
country_code |
denotes |
in |
| tok254 |
1540-1547 |
JJ |
denotes |
similar |
| tok255 |
1548-1553 |
NN |
denotes |
liver |
| tok256 |
1554-1563 |
NN |
denotes |
pathology |
| tok257 |
1563-1564 |
. |
denotes |
. |
| tok258 |
1565-1572 |
RB |
denotes |
Overall |
| tok259 |
1572-1573 |
, |
denotes |
, |
| tok260 |
1574-1578 |
DT |
denotes |
this |
| lookup28 |
1574-1578 |
time_modifier |
denotes |
this |
| tok261 |
1579-1584 |
NN |
denotes |
study |
| tok262 |
1585-1597 |
VBZ |
denotes |
demonstrates |
| tok263 |
1598-1602 |
IN |
denotes |
that |
| tok264 |
1603-1619 |
JJ |
denotes |
structure-guided |
| tok265 |
1620-1631 |
NNS |
denotes |
mutagenesis |
| tok266 |
1632-1636 |
VBZ |
denotes |
aids |
| event33 |
1632-1636 |
OCCURRENCE |
denotes |
aids |
| tok267 |
1637-1640 |
DT |
denotes |
the |
| tok268 |
1641-1655 |
NN |
denotes |
identification |
| tok269 |
1656-1658 |
IN |
denotes |
of |
| tok270 |
1659-1667 |
JJ |
denotes |
critical |
| tok271 |
1668-1680 |
NNS |
denotes |
determinants |
| tok272 |
1681-1683 |
IN |
denotes |
of |
| tok273 |
1684-1687 |
NNP |
denotes |
PLP |
| tok274 |
1687-1688 |
CD |
denotes |
2 |
| tok275 |
1688-1689 |
: |
denotes |
- |
| tok276 |
1689-1698 |
NN |
denotes |
ubiquitin |
| tok277 |
1699-1706 |
JJ |
denotes |
complex |
| tok278 |
1706-1707 |
, |
denotes |
, |
| tok279 |
1708-1711 |
CC |
denotes |
and |
| tok280 |
1712-1716 |
IN |
denotes |
that |
| tok281 |
1717-1720 |
NNP |
denotes |
PLP |
| tok282 |
1720-1721 |
CD |
denotes |
2 |
| tok283 |
1722-1725 |
NNP |
denotes |
DUB |
| tok284 |
1726-1734 |
NN |
denotes |
activity |
| tok285 |
1735-1740 |
VBZ |
denotes |
plays |
| event14 |
1735-1740 |
OCCURRENCE |
denotes |
plays |
| tok286 |
1741-1742 |
DT |
denotes |
a |
| tok287 |
1743-1747 |
NN |
denotes |
role |
| tok288 |
1748-1750 |
IN |
denotes |
as |
| lookup29 |
1748-1750 |
country_code |
denotes |
as |
| tok289 |
1751-1753 |
DT |
denotes |
an |
| lookup30 |
1751-1753 |
country_code |
denotes |
an |
| tok290 |
1754-1764 |
NN |
denotes |
interferon |
| tok291 |
1765-1775 |
NN |
denotes |
antagonist |
| tok292 |
1776-1778 |
IN |
denotes |
in |
| lookup31 |
1776-1778 |
country_code |
denotes |
in |
| tok293 |
1779-1790 |
JJ |
denotes |
coronavirus |
| tok294 |
1791-1803 |
NNS |
denotes |
pathogenesis |
| tok295 |
1803-1804 |
. |
denotes |
. |
| tok296 |
1804-1814 |
NNP |
denotes |
IMPORTANCE |
| tok297 |
1815-1828 |
NNP |
denotes |
Coronaviruses |
| tok298 |
1829-1835 |
VB |
denotes |
employ |
| event23 |
1829-1835 |
OCCURRENCE |
denotes |
employ |
| tok299 |
1836-1837 |
DT |
denotes |
a |
| tok300 |
1838-1845 |
JJ |
denotes |
genetic |
| tok301 |
1846-1853 |
NN |
denotes |
economy |
| tok302 |
1854-1856 |
IN |
denotes |
by |
| lookup32 |
1854-1856 |
country_code |
denotes |
by |
| tok303 |
1857-1865 |
VBG |
denotes |
encoding |
| event29 |
1857-1865 |
OCCURRENCE |
denotes |
encoding |
| tok304 |
1866-1881 |
NN |
denotes |
multifunctional |
| tok305 |
1882-1890 |
NNS |
denotes |
proteins |
| tok306 |
1891-1895 |
WDT |
denotes |
that |
| tok307 |
1896-1904 |
NN |
denotes |
function |
| tok308 |
1905-1907 |
IN |
denotes |
in |
| lookup33 |
1905-1907 |
country_code |
denotes |
in |
| tok309 |
1908-1913 |
JJ |
denotes |
viral |
| tok310 |
1914-1925 |
NN |
denotes |
replication |
| tok311 |
1926-1929 |
CC |
denotes |
and |
| tok312 |
1930-1934 |
RB |
denotes |
also |
| tok313 |
1935-1941 |
VB |
denotes |
modify |
| event5 |
1935-1941 |
OCCURRENCE |
denotes |
modify |
| tok314 |
1942-1945 |
DT |
denotes |
the |
| tok315 |
1946-1950 |
NN |
denotes |
host |
| tok316 |
1951-1962 |
NN |
denotes |
environment |
| tok317 |
1963-1965 |
TO |
denotes |
to |
| lookup34 |
1963-1965 |
country_code |
denotes |
to |
| tok318 |
1966-1972 |
VB |
denotes |
disarm |
| event10 |
1966-1972 |
OCCURRENCE |
denotes |
disarm |
| tok319 |
1973-1976 |
DT |
denotes |
the |
| tok320 |
1977-1983 |
JJ |
denotes |
innate |
| tok321 |
1984-1990 |
JJ |
denotes |
immune |
| tok322 |
1991-1999 |
NN |
denotes |
response |
| tok323 |
1999-2000 |
. |
denotes |
. |
| tok324 |
2001-2004 |
DT |
denotes |
The |
| tok325 |
2005-2016 |
JJ |
denotes |
coronavirus |
| tok326 |
2017-2028 |
JJ |
denotes |
papain-like |
| tok327 |
2029-2037 |
NN |
denotes |
protease |
| tok328 |
2038-2039 |
CD |
denotes |
2 |
| tok329 |
2040-2041 |
( |
denotes |
( |
| tok330 |
2041-2044 |
NNP |
denotes |
PLP |
| tok331 |
2044-2045 |
LS |
denotes |
2 |
| tok332 |
2045-2046 |
) |
denotes |
) |
| tok333 |
2047-2053 |
NN |
denotes |
domain |
| tok334 |
2054-2063 |
VBZ |
denotes |
possesses |
| tok335 |
2064-2072 |
NN |
denotes |
protease |
| tok336 |
2073-2081 |
NN |
denotes |
activity |
| tok337 |
2081-2082 |
, |
denotes |
, |
| tok338 |
2083-2088 |
WDT |
denotes |
which |
| tok339 |
2089-2096 |
NNS |
denotes |
cleaves |
| tok340 |
2097-2100 |
DT |
denotes |
the |
| tok341 |
2101-2106 |
JJ |
denotes |
viral |
| tok342 |
2107-2116 |
NN |
denotes |
replicase |
| tok343 |
2117-2128 |
NN |
denotes |
polyprotein |
| tok344 |
2128-2129 |
, |
denotes |
, |
| tok345 |
2130-2133 |
CC |
denotes |
and |
| tok346 |
2134-2138 |
RB |
denotes |
also |
| tok347 |
2139-2142 |
NNP |
denotes |
DUB |
| tok348 |
2143-2151 |
NN |
denotes |
activity |
| tok349 |
2152-2153 |
( |
denotes |
( |
| lookup35 |
2153-2155 |
country_code |
denotes |
de |
| lookup36 |
2153-2155 |
surname |
denotes |
de |
| tok350 |
2153-2167 |
JJ |
denotes |
de-conjugating |
| tok351 |
2168-2177 |
NN |
denotes |
ubiquitin |
| tok352 |
2177-2178 |
NN |
denotes |
/ |
| tok353 |
2178-2192 |
JJ |
denotes |
ubiquitin-like |
| tok354 |
2193-2202 |
NNS |
denotes |
molecules |
| tok355 |
2203-2207 |
IN |
denotes |
from |
| tok356 |
2208-2216 |
VBN |
denotes |
modified |
| event20 |
2208-2216 |
OCCURRENCE |
denotes |
modified |
| tok357 |
2217-2227 |
NNS |
denotes |
substrates |
| tok358 |
2227-2228 |
) |
denotes |
) |
| tok359 |
2229-2234 |
VBG |
denotes |
using |
| event24 |
2229-2234 |
OCCURRENCE |
denotes |
using |
| tok360 |
2235-2244 |
JJ |
denotes |
identical |
| tok361 |
2245-2254 |
JJ |
denotes |
catalytic |
| tok362 |
2255-2263 |
NNS |
denotes |
residues |
| tok363 |
2263-2264 |
. |
denotes |
. |
| tok364 |
2265-2267 |
TO |
denotes |
To |
| tok365 |
2268-2276 |
VB |
denotes |
separate |
| event9 |
2268-2276 |
OCCURRENCE |
denotes |
separate |
| tok366 |
2277-2280 |
DT |
denotes |
the |
| tok367 |
2281-2284 |
NNP |
denotes |
DUB |
| tok368 |
2285-2293 |
NN |
denotes |
activity |
| tok369 |
2294-2298 |
IN |
denotes |
from |
| tok370 |
2299-2302 |
DT |
denotes |
the |
| tok371 |
2303-2311 |
NN |
denotes |
protease |
| tok372 |
2312-2320 |
NN |
denotes |
activity |
| tok373 |
2320-2321 |
, |
denotes |
, |
| tok374 |
2322-2324 |
PRP |
denotes |
we |
| tok375 |
2325-2333 |
VBN |
denotes |
employed |
| event13 |
2325-2333 |
OCCURRENCE |
denotes |
employed |
| tok376 |
2334-2335 |
DT |
denotes |
a |
| tok377 |
2336-2352 |
JJ |
denotes |
structure-guided |
| tok378 |
2353-2364 |
NNS |
denotes |
mutagenesis |
| tok379 |
2365-2373 |
VBP |
denotes |
approach |
| event17 |
2365-2373 |
I_STATE |
denotes |
approach |
| tok380 |
2374-2377 |
CC |
denotes |
and |
| tok381 |
2378-2388 |
VBN |
denotes |
identified |
| event7 |
2378-2388 |
OCCURRENCE |
denotes |
identified |
| tok382 |
2389-2397 |
NNS |
denotes |
residues |
| tok383 |
2398-2402 |
WDT |
denotes |
that |
| tok384 |
2403-2406 |
VBP |
denotes |
are |
| tok385 |
2407-2416 |
JJ |
denotes |
important |
| tok386 |
2417-2420 |
IN |
denotes |
for |
| tok387 |
2421-2438 |
JJ |
denotes |
ubiquitin-binding |
| tok388 |
2438-2439 |
. |
denotes |
. |
| tok389 |
2440-2442 |
PRP |
denotes |
We |
| lookup37 |
2440-2442 |
stop |
denotes |
We |
| tok390 |
2443-2448 |
VBD |
denotes |
found |
| event11 |
2443-2448 |
OCCURRENCE |
denotes |
found |
| tok391 |
2449-2453 |
IN |
denotes |
that |
| tok392 |
2454-2462 |
VBG |
denotes |
mutating |
| event28 |
2454-2462 |
OCCURRENCE |
denotes |
mutating |
| tok393 |
2463-2466 |
DT |
denotes |
the |
| tok394 |
2467-2484 |
JJ |
denotes |
ubiquitin-binding |
| tok395 |
2485-2493 |
NNS |
denotes |
residues |
| tok396 |
2494-2501 |
NNS |
denotes |
results |
| tok397 |
2502-2504 |
IN |
denotes |
in |
| lookup38 |
2502-2504 |
country_code |
denotes |
in |
| tok398 |
2505-2506 |
DT |
denotes |
a |
| tok399 |
2507-2510 |
NNP |
denotes |
PLP |
| tok400 |
2510-2511 |
CD |
denotes |
2 |
| tok401 |
2512-2516 |
WDT |
denotes |
that |
| tok402 |
2517-2520 |
VBZ |
denotes |
has |
| tok403 |
2521-2528 |
VBN |
denotes |
reduced |
| event8 |
2521-2528 |
OCCURRENCE |
denotes |
reduced |
| tok404 |
2529-2532 |
NNP |
denotes |
DUB |
| tok405 |
2533-2541 |
NN |
denotes |
activity |
| tok406 |
2542-2545 |
CC |
denotes |
but |
| tok407 |
2546-2553 |
VBZ |
denotes |
retains |
| tok408 |
2554-2562 |
NN |
denotes |
protease |
| tok409 |
2563-2571 |
NN |
denotes |
activity |
| tok410 |
2571-2572 |
. |
denotes |
. |
| tok411 |
2573-2575 |
PRP |
denotes |
We |
| lookup39 |
2573-2575 |
stop |
denotes |
We |
| tok412 |
2576-2586 |
VBN |
denotes |
engineered |
| event3 |
2576-2586 |
OCCURRENCE |
denotes |
engineered |
| tok413 |
2587-2588 |
DT |
denotes |
a |
| tok414 |
2589-2600 |
JJ |
denotes |
recombinant |
| tok415 |
2601-2607 |
NN |
denotes |
murine |
| tok416 |
2608-2619 |
JJ |
denotes |
coronavirus |
| tok417 |
2620-2622 |
TO |
denotes |
to |
| lookup40 |
2620-2622 |
country_code |
denotes |
to |
| tok418 |
2623-2630 |
VB |
denotes |
express |
| event22 |
2623-2630 |
OCCURRENCE |
denotes |
express |
| tok419 |
2631-2634 |
DT |
denotes |
the |
| tok420 |
2635-2638 |
NNP |
denotes |
DUB |
| tok421 |
2639-2645 |
JJ |
denotes |
mutant |
| tok422 |
2646-2649 |
CC |
denotes |
and |
| tok423 |
2650-2656 |
VBD |
denotes |
showed |
| event25 |
2650-2656 |
OCCURRENCE |
denotes |
showed |
| tok424 |
2657-2661 |
IN |
denotes |
that |
| tok425 |
2662-2665 |
DT |
denotes |
the |
| tok426 |
2666-2669 |
NNP |
denotes |
DUB |
| tok427 |
2670-2676 |
JJ |
denotes |
mutant |
| tok428 |
2677-2682 |
NN |
denotes |
virus |
| tok429 |
2683-2692 |
VBN |
denotes |
activated |
| event16 |
2683-2692 |
OCCURRENCE |
denotes |
activated |
| tok430 |
2693-2695 |
DT |
denotes |
an |
| lookup41 |
2693-2695 |
country_code |
denotes |
an |
| tok431 |
2696-2703 |
JJR |
denotes |
earlier |
| tok432 |
2704-2708 |
NN |
denotes |
type |
| tok433 |
2709-2710 |
PRP |
denotes |
I |
| lookup42 |
2709-2710 |
stop |
denotes |
I |
| tok434 |
2711-2721 |
NN |
denotes |
interferon |
| tok435 |
2722-2730 |
NN |
denotes |
response |
| tok436 |
2731-2733 |
IN |
denotes |
in |
| lookup43 |
2731-2733 |
country_code |
denotes |
in |
| tok437 |
2734-2745 |
NNS |
denotes |
macrophages |
| tok438 |
2746-2749 |
CC |
denotes |
and |
| tok439 |
2750-2759 |
VBN |
denotes |
exhibited |
| tok440 |
2760-2767 |
VBN |
denotes |
reduced |
| event15 |
2760-2767 |
OCCURRENCE |
denotes |
reduced |
| tok441 |
2768-2779 |
NN |
denotes |
replication |
| tok442 |
2780-2782 |
IN |
denotes |
in |
| lookup44 |
2780-2782 |
country_code |
denotes |
in |
| tok443 |
2783-2787 |
NNS |
denotes |
mice |
| tok444 |
2787-2788 |
. |
denotes |
. |
| tok445 |
2789-2792 |
DT |
denotes |
The |
| tok446 |
2793-2800 |
NNS |
denotes |
results |
| tok447 |
2801-2803 |
IN |
denotes |
of |
| tok448 |
2804-2808 |
DT |
denotes |
this |
| lookup45 |
2804-2808 |
time_modifier |
denotes |
this |
| tok449 |
2809-2814 |
NN |
denotes |
study |
| tok450 |
2815-2826 |
VB |
denotes |
demonstrate |
| tok451 |
2827-2831 |
IN |
denotes |
that |
| tok452 |
2832-2835 |
NNP |
denotes |
PLP |
| tok453 |
2835-2836 |
CD |
denotes |
2 |
| tok454 |
2836-2837 |
NN |
denotes |
/ |
| tok455 |
2837-2840 |
NNP |
denotes |
DUB |
| tok456 |
2841-2843 |
VBZ |
denotes |
is |
| lookup46 |
2841-2843 |
country_code |
denotes |
is |
| tok457 |
2844-2846 |
DT |
denotes |
an |
| lookup47 |
2844-2846 |
country_code |
denotes |
an |
| tok458 |
2847-2857 |
NN |
denotes |
interferon |
| tok459 |
2858-2868 |
NN |
denotes |
antagonist |
| tok460 |
2869-2872 |
CC |
denotes |
and |
| tok461 |
2873-2874 |
DT |
denotes |
a |
| tok462 |
2875-2884 |
NN |
denotes |
virulence |
| tok463 |
2885-2890 |
NN |
denotes |
trait |
| tok464 |
2891-2893 |
IN |
denotes |
of |
| tok465 |
2894-2907 |
NNS |
denotes |
coronaviruses |
| tok466 |
2907-2908 |
. |
denotes |
. |
