Id |
Subject |
Object |
Predicate |
Lexical cue |
tao:has_database_id |
768 |
53-65 |
Disease |
denotes |
Inflammation |
MESH:D007249 |
769 |
112-137 |
Disease |
denotes |
cardiovascular impairment |
MESH:D002318 |
770 |
156-164 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |
762 |
177-185 |
Species |
denotes |
SARS-CoV |
Tax:694009 |
771 |
190-208 |
Disease |
denotes |
MERS-CoV infection |
MESH:D018352 |
772 |
215-230 |
Disease |
denotes |
CoV-2 infection |
MESH:C000657245 |
773 |
546-562 |
Disease |
denotes |
viral infections |
MESH:D001102 |
774 |
767-788 |
Disease |
denotes |
cardiovascular injury |
MESH:D002318 |
775 |
802-822 |
Disease |
denotes |
SARS-CoV-2 infection |
MESH:C000657245 |
749 |
918-931 |
Gene |
denotes |
interleukin-6 |
Gene:3569 |
750 |
933-937 |
Gene |
denotes |
IL-6 |
Gene:3569 |
751 |
940-944 |
Gene |
denotes |
IL-7 |
Gene:3574 |
752 |
946-950 |
Gene |
denotes |
IL-8 |
Gene:3576 |
753 |
952-956 |
Gene |
denotes |
IL-9 |
Gene:3578 |
754 |
958-963 |
Gene |
denotes |
IL-10 |
Gene:3586 |
755 |
965-970 |
Gene |
denotes |
IL-1β |
Gene:3552 |
756 |
972-978 |
Gene |
denotes |
IL-1RA |
Gene:3557 |
757 |
980-1007 |
Gene |
denotes |
tumor necrosis factor-alpha |
Gene:7124 |
758 |
1009-1014 |
Gene |
denotes |
TNF-α |
Gene:7124 |
759 |
1017-1065 |
Gene |
denotes |
granulocyte-macrophage colony-stimulating factor |
Gene:1437 |
760 |
1093-1132 |
Gene |
denotes |
macrophage inflammatory protein 1 alpha |
Gene:1230 |
761 |
1203-1237 |
Gene |
denotes |
vascular endothelial growth factor |
Gene:7422 |
776 |
1254-1262 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |
763 |
1263-1271 |
Species |
denotes |
patients |
Tax:9606 |
764 |
1291-1299 |
Species |
denotes |
patients |
Tax:9606 |
777 |
1503-1512 |
Disease |
denotes |
mortality |
MESH:D003643 |
765 |
1522-1530 |
Species |
denotes |
patients |
Tax:9606 |
778 |
1536-1544 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |
779 |
1629-1637 |
Disease |
denotes |
necrosis |
MESH:D009336 |
780 |
2184-2192 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |
766 |
2193-2201 |
Species |
denotes |
patients |
Tax:9606 |
767 |
2332-2340 |
Species |
denotes |
patients |
Tax:9606 |
781 |
2346-2354 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |
715 |
2547-2555 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |
714 |
2556-2564 |
Species |
denotes |
patients |
Tax:9606 |
665 |
2675-2686 |
Chemical |
denotes |
Tocilizumab |
MESH:C502936 |
651 |
2691-2695 |
Gene |
denotes |
IL-6 |
Gene:3569 |
678 |
2779-2787 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |
666 |
2871-2887 |
Chemical |
denotes |
tocilizumab
• N |
|
667 |
2922-2933 |
Chemical |
denotes |
tocilizumab |
MESH:C502936 |
679 |
2965-2970 |
Disease |
denotes |
fever |
MESH:D005334 |
680 |
3043-3048 |
Disease |
denotes |
fever |
MESH:D005334 |
681 |
3126-3143 |
Disease |
denotes |
pulmonary lesions |
MESH:D008171 |
682 |
3192-3213 |
Disease |
denotes |
pending
• Tocilizumab |
|
683 |
3306-3363 |
Disease |
denotes |
multi-organ damage (ChiCTR2000029765, 2020)
• Tocilizumab |
MESH:C564969 |
684 |
3496-3504 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |
685 |
3782-3791 |
Disease |
denotes |
mortality |
MESH:D003643 |
659 |
3867-3875 |
Species |
denotes |
patients |
Tax:9606 |
652 |
3881-3899 |
Gene |
denotes |
C-reactive protein |
Gene:1401 |
653 |
3901-3904 |
Gene |
denotes |
CRP |
Gene:1401 |
658 |
3961-3964 |
Gene |
denotes |
CRP |
Gene:1401 |
686 |
4061-4070 |
Disease |
denotes |
mortality |
MESH:D003643 |
687 |
4315-4323 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |
688 |
4411-4414 |
Disease |
denotes |
CVD |
MESH:D002318 |
668 |
4491-4502 |
Chemical |
denotes |
tocilizumab |
MESH:C502936 |
689 |
4559-4564 |
Disease |
denotes |
Fever |
MESH:D005334 |
669 |
4598-4600 |
Chemical |
denotes |
O2 |
MESH:D010100 |
654 |
4647-4651 |
Gene |
denotes |
IL-6 |
Gene:3569 |
690 |
4664-4693 |
Disease |
denotes |
lung lesion improvement
• All |
MESH:D008171 |
660 |
4694-4702 |
Species |
denotes |
patients |
Tax:9606 |
670 |
4751-4770 |
Chemical |
denotes |
group
• Tocilizumab |
|
691 |
4791-4799 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |
671 |
4893-4911 |
Chemical |
denotes |
methylprednisolone |
MESH:D008775 |
672 |
4924-4935 |
Chemical |
denotes |
tocilizumab |
MESH:C502936 |
692 |
5021-5030 |
Disease |
denotes |
tachypnea |
MESH:D059246 |
655 |
5041-5044 |
Gene |
denotes |
CRP |
Gene:1401 |
673 |
5133-5151 |
Chemical |
denotes |
methylprednisolone |
MESH:D008775 |
674 |
5156-5171 |
Chemical |
denotes |
tocilizumab
• N |
|
675 |
5212-5230 |
Chemical |
denotes |
methylprednisolone |
MESH:D008775 |
676 |
5354-5365 |
Chemical |
denotes |
tocilizumab |
MESH:C502936 |
693 |
5535-5544 |
Disease |
denotes |
mortality |
MESH:D003643 |
661 |
5686-5694 |
Species |
denotes |
patients |
Tax:9606 |
656 |
6247-6250 |
Gene |
denotes |
CRP |
Gene:1401 |
694 |
6341-6353 |
Disease |
denotes |
inflammation |
MESH:D007249 |
657 |
6440-6444 |
Gene |
denotes |
IL-1 |
Gene:3553 |
695 |
6511-6514 |
Disease |
denotes |
CVD |
MESH:D002318 |
696 |
6529-6537 |
Disease |
denotes |
diabetes |
MESH:D003920 |
697 |
6539-6546 |
Disease |
denotes |
obesity |
MESH:D009765 |
698 |
6559-6582 |
Disease |
denotes |
hypertension • Anakinra |
MESH:D006973 |
677 |
6614-6628 |
Chemical |
denotes |
1–3
• Anakinra |
|
699 |
6667-6672 |
Disease |
denotes |
Fever |
MESH:D005334 |
662 |
6713-6721 |
Species |
denotes |
patients |
Tax:9606 |
663 |
6916-6924 |
Species |
denotes |
patients |
Tax:9606 |
700 |
6930-6942 |
Disease |
denotes |
hypertension |
MESH:D006973 |
701 |
6953-6956 |
Disease |
denotes |
CVD |
MESH:D002318 |
702 |
6993-7019 |
Disease |
denotes |
Ana-COVID study
• Anakinra |
MESH:C000657245 |
703 |
7024-7032 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |
704 |
7162-7165 |
Disease |
denotes |
CVD |
MESH:D002318 |
705 |
7167-7179 |
Disease |
denotes |
hypertension |
MESH:D006973 |
706 |
7181-7187 |
Disease |
denotes |
stroke |
MESH:D020521 |
707 |
7189-7200 |
Disease |
denotes |
cardiopathy |
MESH:C536187 |
708 |
7488-7496 |
Disease |
denotes |
death HR |
MESH:D003643 |
664 |
7569-7577 |
Species |
denotes |
patients |
Tax:9606 |
709 |
7590-7598 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |
710 |
7599-7608 |
Disease |
denotes |
infection |
MESH:D007239 |
711 |
7631-7634 |
Disease |
denotes |
CVD |
MESH:D002318 |
828 |
7776-7792 |
Disease |
denotes |
viral infections |
MESH:D001102 |
808 |
8156-8161 |
Gene |
denotes |
NF-κB |
Gene:4790 |
809 |
8164-8200 |
Gene |
denotes |
interferon (IFN) regulatory factor 3 |
Gene:3661 |
825 |
8360-8370 |
Species |
denotes |
SARS-CoV-2 |
Tax:2697049 |
810 |
8392-8397 |
Gene |
denotes |
NF-κB |
Gene:4790 |
811 |
8483-8488 |
Gene |
denotes |
NLRP3 |
Gene:114548 |
812 |
8490-8493 |
Gene |
denotes |
NOD |
Gene:1822 |
813 |
8496-8531 |
Gene |
denotes |
LRR-, and pyrin domain-containing 3 |
|
814 |
8611-8616 |
Gene |
denotes |
NLRP3 |
Gene:114548 |
815 |
8704-8709 |
Gene |
denotes |
NLRP3 |
Gene:114548 |
816 |
8953-8958 |
Gene |
denotes |
NLRP3 |
Gene:114548 |
817 |
9052-9061 |
Gene |
denotes |
caspase-1 |
Gene:834 |
818 |
9134-9152 |
Gene |
denotes |
pro-interleukin-1β |
Gene:3553 |
819 |
9158-9163 |
Gene |
denotes |
IL-1β |
Gene:3552 |
820 |
9231-9236 |
Gene |
denotes |
IL-1β |
Gene:3552 |
821 |
9241-9246 |
Gene |
denotes |
IL-18 |
Gene:3606 |
829 |
9315-9327 |
Disease |
denotes |
inflammation |
MESH:D007249 |
822 |
9336-9341 |
Gene |
denotes |
TNF-α |
Gene:7124 |
823 |
9343-9347 |
Gene |
denotes |
IL-6 |
Gene:3569 |
826 |
9349-9363 |
Chemical |
denotes |
prostaglandins |
MESH:D011453 |
827 |
9368-9380 |
Chemical |
denotes |
leukotrienes |
MESH:D015289 |
830 |
9415-9420 |
Disease |
denotes |
fever |
MESH:D005334 |
831 |
9426-9434 |
Disease |
denotes |
fibrosis |
MESH:D005355 |
824 |
9534-9539 |
Gene |
denotes |
NLRP3 |
Gene:114548 |
832 |
9679-9691 |
Disease |
denotes |
inflammation |
MESH:D007249 |
833 |
9697-9717 |
Disease |
denotes |
SARS-CoVs infections |
MESH:C000657245 |
884 |
9719-9731 |
Disease |
denotes |
Inflammation |
MESH:D007249 |
885 |
9772-9776 |
Disease |
denotes |
CVDs |
|
886 |
9786-9801 |
Disease |
denotes |
atherosclerosis |
MESH:D050197 |
887 |
9803-9815 |
Disease |
denotes |
coagulopathy |
MESH:D001778 |
888 |
9817-9840 |
Disease |
denotes |
coronary artery disease |
MESH:D003324 |
889 |
9916-9924 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |
890 |
9986-9999 |
Disease |
denotes |
erythematosus |
MESH:D008180 |
871 |
10023-10041 |
Gene |
denotes |
C-reactive protein |
Gene:1401 |
872 |
10043-10046 |
Gene |
denotes |
CRP |
Gene:1401 |
891 |
10063-10079 |
Disease |
denotes |
hypercoagulation |
MESH:D019851 |
892 |
10084-10122 |
Disease |
denotes |
disseminated intravascular coagulation |
MESH:D004211 |
893 |
10140-10150 |
Disease |
denotes |
thrombosis |
MESH:D013927 |
894 |
10152-10168 |
Disease |
denotes |
thrombocytopenia |
MESH:D013921 |
895 |
10173-10181 |
Disease |
denotes |
gangrene |
MESH:D005734 |
873 |
10298-10302 |
Gene |
denotes |
TNFα |
Gene:7124 |
879 |
10306-10314 |
Species |
denotes |
patients |
Tax:9606 |
896 |
10409-10441 |
Disease |
denotes |
ventricular dilation/hypertrophy |
MESH:D002312 |
897 |
10451-10474 |
Disease |
denotes |
ventricular dysfunction |
MESH:D018754 |
874 |
10557-10562 |
Gene |
denotes |
IL-1β |
Gene:3552 |
875 |
10567-10571 |
Gene |
denotes |
IL-6 |
Gene:3569 |
880 |
10591-10599 |
Species |
denotes |
patients |
Tax:9606 |
898 |
10611-10622 |
Disease |
denotes |
myocarditis |
MESH:D009205 |
876 |
10671-10675 |
Gene |
denotes |
IL-6 |
Gene:3569 |
899 |
10709-10725 |
Disease |
denotes |
long QT-syndrome |
MESH:D008133 |
881 |
10729-10737 |
Species |
denotes |
patients |
Tax:9606 |
900 |
10752-10764 |
Disease |
denotes |
inflammation |
MESH:D007249 |
901 |
10794-10805 |
Disease |
denotes |
arrhythmias |
MESH:D001145 |
902 |
10814-10832 |
Disease |
denotes |
torsade de pointes |
MESH:D016171 |
877 |
10882-10886 |
Gene |
denotes |
IL-6 |
Gene:3569 |
903 |
10959-10976 |
Disease |
denotes |
coronary syndrome |
MESH:D054058 |
904 |
10981-10991 |
Disease |
denotes |
chronic HF |
MESH:D002908 |
878 |
11054-11058 |
Gene |
denotes |
IL-8 |
Gene:3576 |
882 |
11076-11084 |
Species |
denotes |
patients |
Tax:9606 |
905 |
11129-11138 |
Disease |
denotes |
mortality |
MESH:D003643 |
883 |
11321-11329 |
Species |
denotes |
patients |
Tax:9606 |
906 |
11335-11343 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |
907 |
11437-11451 |
Disease |
denotes |
cardiac injury |
MESH:D006331 |
918 |
11553-11574 |
Disease |
denotes |
cardiac complications |
MESH:D005117 |
919 |
11588-11596 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |
917 |
11601-11609 |
Species |
denotes |
patients |
Tax:9606 |
920 |
11629-11636 |
Disease |
denotes |
obesity |
MESH:D009765 |
921 |
11638-11656 |
Disease |
denotes |
metabolic syndrome |
MESH:D024821 |
922 |
11658-11670 |
Disease |
denotes |
hypertension |
MESH:D006973 |
923 |
11675-11683 |
Disease |
denotes |
diabetes |
MESH:D003920 |
924 |
12114-12139 |
Disease |
denotes |
cardiovascular impairment |
MESH:D002318 |
925 |
12159-12167 |
Disease |
denotes |
COVID-19 |
MESH:C000657245 |