LitCovid-ArguminSci  

PubMed:32031570 JSONTXT 38 Projects

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Id Subject Object Predicate Lexical cue
T1 0-117 DRI_Background denotes Clinical Characteristics of 138 Hospitalized Patients With 2019 Novel Coronavirus-Infected Pneumonia in Wuhan, China.
T2 118-229 DRI_Background denotes Importance: In December 2019, novel coronavirus (2019-nCoV)-infected pneumonia (NCIP) occurred in Wuhan, China.
T3 230-352 DRI_Background denotes The number of cases has increased rapidly but information on the clinical characteristics of affected patients is limited.
T4 353-433 DRI_Background denotes Objective: To describe the epidemiological and clinical characteristics of NCIP.
T5 743-884 DRI_Background denotes Main Outcomes and Measures: Epidemiological, demographic, clinical, laboratory, radiological, and treatment data were collected and analyzed.
T6 885-966 DRI_Challenge denotes Outcomes of critically ill patients and noncritically ill patients were compared.
T7 967-1168 DRI_Approach denotes Presumed hospital-related transmission was suspected if a cluster of health professionals or hospitalized patients in the same wards became infected and a possible source of infection could be tracked.
T8 1169-1319 DRI_Background denotes Results: Of 138 hospitalized patients with NCIP, the median age was 56 years (interquartile range, 42-68; range, 22-92 years) and 75 (54.3%) were men.
T9 1320-1490 DRI_Background denotes Hospital-associated transmission was suspected as the presumed mechanism of infection for affected health professionals (40 [29%]) and hospitalized patients (17 [12.3%]).
T10 1491-1586 DRI_Background denotes Common symptoms included fever (136 [98.6%]), fatigue (96 [69.6%]), and dry cough (82 [59.4%]).
T11 1985-2212 DRI_Background denotes Most patients received antiviral therapy (oseltamivir, 124 [89.9%]), and many received antibacterial therapy (moxifloxacin, 89 [64.4%]; ceftriaxone, 34 [24.6%]; azithromycin, 25 [18.1%]) and glucocorticoid therapy (62 [44.9%]).
T12 2213-2425 DRI_Background denotes Thirty-six patients (26.1%) were transferred to the intensive care unit (ICU) because of complications, including acute respiratory distress syndrome (22 [61.1%]), arrhythmia (16 [44.4%]), and shock (11 [30.6%]).
T13 2426-2547 DRI_Outcome denotes The median time from first symptom to dyspnea was 5.0 days, to hospital admission was 7.0 days, and to ARDS was 8.0 days.
T14 2548-2873 DRI_Background denotes Patients treated in the ICU (n = 36), compared with patients not treated in the ICU (n = 102), were older (median age, 66 years vs 51 years), were more likely to have underlying comorbidities (26 [72.2%] vs 38 [37.3%]), and were more likely to have dyspnea (23 [63.9%] vs 20 [19.6%]), and anorexia (24 [66.7%] vs 31 [30.4%]).
T15 2874-3094 DRI_Background denotes Of the 36 cases in the ICU, 4 (11.1%) received high-flow oxygen therapy, 15 (41.7%) received noninvasive ventilation, and 17 (47.2%) received invasive ventilation (4 were switched to extracorporeal membrane oxygenation).
T16 3095-3237 DRI_Outcome denotes As of February 3, 47 patients (34.1%) were discharged and 6 died (overall mortality, 4.3%), but the remaining patients are still hospitalized.
T17 3238-3330 DRI_Approach denotes Among those discharged alive (n = 47), the median hospital stay was 10 days (IQR, 7.0-14.0).
T18 3331-3602 DRI_Background denotes Conclusions and Relevance: In this single-center case series of 138 hospitalized patients with confirmed NCIP in Wuhan, China, presumed hospital-related transmission of 2019-nCoV was suspected in 41% of patients, 26% of patients received ICU care, and mortality was 4.3%.