LitCovid-ArguminSci  

PubMed:32026671 JSONTXT 37 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1 0-85 DRI_Background denotes [Analysis of clinical features of 29 patients with 2019 novel coronavirus pneumonia].
T2 86-285 DRI_Background denotes Objective: To analyze the clinical characteristics of 2019 novel coronavirus (2019-nCoV) pneumonia and to investigate the correlation between serum inflammatory cytokines and severity of the disease.
T3 286-510 DRI_Background denotes Methods: 29 patients with 2019-ncov admitted to the isolation ward of Tongji hospital affiliated to Tongji medical college of Huazhong University of Science and Technology in January 2020 were selected as the study subjects.
T4 511-644 DRI_Background denotes Clinical data were collected and the general information, clinical symptoms, blood test and CT imaging characteristics were analyzed.
T5 645-794 DRI_Background denotes According to the relevant diagnostic criteria, the patients were divided into three groups: mild (15 cases), severe (9 cases) and critical (5 cases).
T6 795-1065 DRI_Approach denotes The expression levels of inflammatory cytokines and other markers in the serum of each group were detected, and the changes of these indicators of the three groups were compared and analyzed, as well as their relationship with the clinical classification of the disease.
T7 1066-1194 DRI_Challenge denotes Results: (1) The main symptoms of 2019-nCoV pneumonia was fever (28/29) with or without respiratory and other systemic symptoms.
T8 1195-1278 DRI_Background denotes Two patients died with underlying disease and co-bacterial infection, respectively.
T9 1279-1496 DRI_Approach denotes (2) The blood test of the patients showed normal or decreased white blood cell count (23/29), decreased lymphocyte count (20/29), increased hypersensitive C reactive protein (hs-CRP) (27/29), and normal procalcitonin.
T10 1497-1620 DRI_Background denotes In most patients,serum lactate dehydrogenase (LDH) was significantly increased (20/29), while albumin was decreased(15/29).
T11 1781-1899 DRI_Background denotes (3) CT findings of typical cases were single or multiple patchy ground glass shadows accompanied by septal thickening.
T12 1900-2053 DRI_Outcome denotes When the disease progresses, the lesion increases and the scope expands, and the ground glass shadow coexists with the solid shadow or the stripe shadow.
T13 2334-2535 DRI_Background denotes However, there were no statistically significant differences in serum levels of tumor necrosis factor-alpha (TNF-α), IL-1, IL-8, IL-10, hs-CRP, lymphocyte count and LDH among the three groups (P>0.05).
T14 2536-2647 DRI_Challenge denotes Conclusion: The clinical characteristics of 2019-nCoV pneumonia are similar to those of common viral pneumonia.
T15 2648-2731 DRI_Approach denotes High resolution CT is of great value in the differential diagnosis of this disease.
T16 2732-2877 DRI_Challenge denotes The increased expression of IL-2R and IL-6 in serum is expected to predict the severity of the 2019-nCoV pneumonia and the prognosis of patients.