Id |
Subject |
Object |
Predicate |
Lexical cue |
T1 |
0-78 |
Sentence |
denotes |
Structure-activity relationships of a series of novel topical corticosteroids. |
T1 |
0-78 |
Sentence |
denotes |
Structure-activity relationships of a series of novel topical corticosteroids. |
T2 |
79-183 |
Sentence |
denotes |
The effect of various heteroaroyl groups in the 17-position of topical corticosteroids has been studied. |
T2 |
79-183 |
Sentence |
denotes |
The effect of various heteroaroyl groups in the 17-position of topical corticosteroids has been studied. |
T3 |
184-329 |
Sentence |
denotes |
The corticosteroids esterified at C17 were of 9 alpha,11 beta-dichloro, 9 alpha-chloro 11 beta-hydroxy and 9 alpha-fluoro 11 beta-hydroxy series. |
T3 |
184-329 |
Sentence |
denotes |
The corticosteroids esterified at C17 were of 9 alpha,11 beta-dichloro, 9 alpha-chloro 11 beta-hydroxy and 9 alpha-fluoro 11 beta-hydroxy series. |
T4 |
330-474 |
Sentence |
denotes |
Among the 17-acyl groups 2'-furoates were most extensively investigated, although 2'-thenoates, 3'-thenoates and 3'-furoates were also examined. |
T4 |
330-474 |
Sentence |
denotes |
Among the 17-acyl groups 2'-furoates were most extensively investigated, although 2'-thenoates, 3'-thenoates and 3'-furoates were also examined. |
T5 |
475-551 |
Sentence |
denotes |
Many of these esters exhibited enhanced topical anti-inflammatory potencies. |
T5 |
475-551 |
Sentence |
denotes |
Many of these esters exhibited enhanced topical anti-inflammatory potencies. |
T6 |
552-714 |
Sentence |
denotes |
The most potent compounds investigated were the 21-chloro 17(2'-furoates) either in the 9 alpha,11 beta-dichloro, or in the 9 alpha-chloro 11 beta-hydroxy series. |
T6 |
552-714 |
Sentence |
denotes |
The most potent compounds investigated were the 21-chloro 17(2'-furoates) either in the 9 alpha,11 beta-dichloro, or in the 9 alpha-chloro 11 beta-hydroxy series. |
T7 |
715-792 |
Sentence |
denotes |
These compounds were at least 6 times as potent as betamethasone 17-valerate. |
T7 |
715-792 |
Sentence |
denotes |
These compounds were at least 6 times as potent as betamethasone 17-valerate. |
T8 |
793-873 |
Sentence |
denotes |
Among 16-substituents studied 16 alpha-methyl compounds had the highest potency. |
T8 |
793-873 |
Sentence |
denotes |
Among 16-substituents studied 16 alpha-methyl compounds had the highest potency. |
T9 |
874-992 |
Sentence |
denotes |
Topical anti-inflammatory potencies were determined by using a 5-day modification of the croton oil ear assay in mice. |
T9 |
874-992 |
Sentence |
denotes |
Topical anti-inflammatory potencies were determined by using a 5-day modification of the croton oil ear assay in mice. |
T10 |
993-1107 |
Sentence |
denotes |
The more potent compounds were also evaluated in the P. ovale induced chronic psoriaform lesion in the guinea-pig. |
T10 |
993-1107 |
Sentence |
denotes |
The more potent compounds were also evaluated in the P. ovale induced chronic psoriaform lesion in the guinea-pig. |