Id |
Subject |
Object |
Predicate |
Lexical cue |
T1 |
0-33 |
Epistemic_statement |
denotes |
Section I: General Considerations |
T2 |
46-185 |
Epistemic_statement |
denotes |
encourage and educate potential breeders on their responsibility to choose healthy, quality bitches and queens for their breeding programs. |
T3 |
291-538 |
Epistemic_statement |
denotes |
The practitioner should counsel prospective breeders regarding the ethical considerations involved in breeding, including the difficulty in placing puppies and kittens in permanent homes and the responsibility incurred in creating these new lives. |
T4 |
539-717 |
Epistemic_statement |
denotes |
Bitches selected for breeding should be mature enough to have genetic clearances for their appropriate breed and young enough to produce reasonable litter size and survivability. |
T5 |
718-793 |
Epistemic_statement |
denotes |
A bitch is at her peak reproductive potential between 2 and 4 years of age. |
T6 |
1146-1244 |
Epistemic_statement |
denotes |
The bitch should be presented to the clinician during proestrus of the anticipated breeding cycle. |
T7 |
1245-1411 |
Epistemic_statement |
denotes |
A complete physical examination should include a rectal examination to evaluate the bony pelvis and a digital vaginal examination to detect any vaginal abnormalities. |
T8 |
1412-1492 |
Epistemic_statement |
denotes |
Brucella canis serology using the rapid-slide agglutination test should be done. |
T9 |
1620-1758 |
Epistemic_statement |
denotes |
Any positive result requires additional testing and should cause a delay in breeding during the cycle in which test results are confirmed. |
T10 |
1759-1892 |
Epistemic_statement |
denotes |
Regardless of previous breeding history, all bitches should be evaluated because the disease is spread orally, as well as venereally. |
T11 |
1893-2113 |
Epistemic_statement |
denotes |
Serologic testing for canine herpes virus should be performed on virgin bitches or in Prenatal care for bitches and queens should begin with the selection of the most desirable members of a potential breeding population. |
T12 |
2114-2280 |
Epistemic_statement |
denotes |
The resources of the important registration bodies and the available databases for evaluation of inherited genetic diseases should be used to select desirable traits. |
T13 |
3067-3169 |
Epistemic_statement |
denotes |
Participation in any health database is voluntary but should be encouraged by practitioners (Box 1-1). |
T14 |
4015-4145 |
Epistemic_statement |
denotes |
Certainly, not every bitch or queen is worthy of reproduction and the practitioner should bitches with a previously negative test. |
T15 |
4231-4311 |
Epistemic_statement |
denotes |
More detailed information pertaining to herpes virus can be found in Chapter 16. |
T16 |
4312-4417 |
Epistemic_statement |
denotes |
Isolation from other canids for 3 weeks before whelping to 3 weeks after whelping should prevent disease. |
T17 |
4470-4557 |
Epistemic_statement |
denotes |
Vaginal cytology should be obtained and stained to assess the epithelial cells present. |
T18 |
4558-4678 |
Epistemic_statement |
denotes |
The bitch should either have her vaccinations brought up to date or have titers performed to assess her antibody levels. |
T19 |
4679-4798 |
Epistemic_statement |
denotes |
The bitch should be well protected against canine distemper and canine parvovirus to maximize maternal antibody levels. |
T20 |
5203-5315 |
Epistemic_statement |
denotes |
The bitch should have baseline laboratory tests performed to assess her suitability for pregnancy and lactation. |
T21 |
5316-5437 |
Epistemic_statement |
denotes |
A bitch with total plasma protein levels of less than 5.0 gm/dl is unlikely to whelp a litter of strong, healthy puppies. |
T22 |
5526-5662 |
Epistemic_statement |
denotes |
If the bitch has a history of infertility or pregnancy loss, a vaginal culture should be performed during the first 5 days of proestrus. |
T23 |
5663-5829 |
Epistemic_statement |
denotes |
Although the value of vaginal cultures is controversial, most clinicians consider a pure culture in significant numbers of a known pathogen to be worthy of treatment. |
T24 |
5830-5963 |
Epistemic_statement |
denotes |
The vaginal culture should be interpreted within the context of patient history, physical examination findings, and vaginal cytology. |
T25 |
6030-6091 |
Epistemic_statement |
denotes |
B. canis is rarely treated in any kennel or colony situation. |
T26 |
6241-6337 |
Epistemic_statement |
denotes |
Antibiotic choice and duration of treatment should be based on safety and efficacy in pregnancy. |
T27 |
6338-6464 |
Epistemic_statement |
denotes |
Bitches that have sustained pregnancy loss may be monitored weekly for hypoluteoidism, which is a poorly documented condition. |
T28 |
6826-6927 |
Epistemic_statement |
denotes |
If the progesterone drops to 10 ng/ml, frequent monitoring of the progesterone levels is recommended. |
T29 |
6928-7030 |
Epistemic_statement |
denotes |
Progesterone values of 5 ng/ml may warrant intervention with an exogenous progestogen supplementation. |
T30 |
7031-7233 |
Epistemic_statement |
denotes |
Exogenous progestogen administration is an extralabel use of any of the available preparations and should always be accompanied by careful client education and a signed release form outlining the risks. |
T31 |
7309-7359 |
Epistemic_statement |
denotes |
The queen should also be examined before breeding. |
T32 |
7360-7511 |
Epistemic_statement |
denotes |
When presented, the queen should have a complete physical examination, including baseline laboratory work, and a fecal examination should be performed. |
T33 |
7512-7613 |
Epistemic_statement |
denotes |
Serology for feline leukemia virus (FeLV) and feline immunodeficiency virus (FIV) should be obtained. |
T34 |
7614-7693 |
Epistemic_statement |
denotes |
Only queens testing negative for these two viruses should be used for breeding. |
T35 |
7744-7861 |
Epistemic_statement |
denotes |
This condition may be avoided by blood typing the queen and breeding to a tom of an appropriate blood type (Box 1-2). |
T36 |
8347-8454 |
Epistemic_statement |
denotes |
The AB blood type is rare and inherited separately as a third allele recessive to A and co-dominant with B. |
T37 |
8832-8973 |
Epistemic_statement |
denotes |
In the case of breedings within catteries, the status of all cats with respect to feline coronavirus (FCOR) should be evaluated (Table 1 -1). |
T38 |
8974-9072 |
Epistemic_statement |
denotes |
To prevent the spread of coronavirus, the tom and the queen should have the same serologic status. |
T39 |
9073-9154 |
Epistemic_statement |
denotes |
The Chlamydia status of cattery members should also be determined using serology. |
T40 |
9155-9335 |
Epistemic_statement |
denotes |
The queen should be vaccinated for feline panleukopenia (FPL), feline herpes virus (FHV), and feline calicivirus (FCV) to prevent clinical disease within the cattery (Table 1 -2). |
T41 |
9336-9403 |
Epistemic_statement |
denotes |
However, vaccination alone may not prevent the spread of infection. |
T42 |
9404-9525 |
Epistemic_statement |
denotes |
Higher levels of maternal antibody may be achieved by boostering the vaccinations just before or at the time of breeding. |
T43 |
9972-10090 |
Epistemic_statement |
denotes |
Thus pregnancy likely involves pregnancy-specific secretion of luteotrophic hormones of placental or pituitary origin. |
T44 |
10091-10213 |
Epistemic_statement |
denotes |
Several studies indicate that prolactin is a major luteotrophic factor in pregnant queens after implantation has occurred. |
T45 |
10214-10264 |
Epistemic_statement |
denotes |
Hypoluteoidism has not been reported in the queen. |
T46 |
10265-10422 |
Epistemic_statement |
denotes |
Progesterone therapy to prevent recurrent pregnancy loss should only be considered when infectious causes of pregnancy loss in the queen have been ruled out. |
T47 |
10491-10712 |
Epistemic_statement |
denotes |
The bitch should be fed a quality, name-brand diet labeled complete for all life stages by the Association of American Feed Control Officials (AAFCO) standards using feeding trials or suitable for pregnancy and lactation. |
T48 |
10794-10966 |
Epistemic_statement |
denotes |
The bitch should be kept in fit condition, and her caloric intake should be appropriate to allow for a weight gain of approximately 36% over her normal prepregnancy weight. |
T49 |
10967-11145 |
Epistemic_statement |
denotes |
The diet should contain a protein level of 25% to 34% and a fat level of at least 18% with a balanced supply of n-6 and n-3 fatty acids, as well as optimum vitamins and minerals. |
T50 |
11146-11231 |
Epistemic_statement |
denotes |
Supplements should be avoided to prevent dietary imbalances and inadvertent toxicity. |
T51 |
11232-11356 |
Epistemic_statement |
denotes |
Calcium supplementation is unnecessary and can result in decreased parathyroid hormone (PTH) stimulation of bone resorption. |
T52 |
11357-11518 |
Epistemic_statement |
denotes |
Eclampsia (puerperal hypocalcemia) can occur when the bitch depends on intestinal calcium absorption rather than on the PTH-stimulated bone calcium mobilization. |
T53 |
11629-11740 |
Epistemic_statement |
denotes |
Immediately after delivery, the bitch or queen should weigh approximately 5% more than her prepregnancy weight. |
T54 |
11814-11975 |
Epistemic_statement |
denotes |
Recently, it has been established that nutrients may influence maternal or fetal gene expression, thereby influencing the metabolic status of an animal for life. |
T55 |
11976-12079 |
Epistemic_statement |
denotes |
It has been established that both prenatal and postnatal nutrition contribute to metabolic programming. |
T56 |
12190-12228 |
Epistemic_statement |
denotes |
This period may be brief or prolonged. |
T57 |
12229-12334 |
Epistemic_statement |
denotes |
The bitch should be encouraged to eat by adding palatable foods to her diet (cooked meat or canned food). |
T58 |
12335-12391 |
Epistemic_statement |
denotes |
If inappetence persists, force feeding may be necessary. |
T59 |
12392-12491 |
Epistemic_statement |
denotes |
Nutritional insufficiency of taurine may result in resorption, abortion, and stillbirth of kittens. |
T60 |
12492-12576 |
Epistemic_statement |
denotes |
Effects of a taurine deficient diet may persist beyond an individual lost pregnancy. |
T61 |
12577-12718 |
Epistemic_statement |
denotes |
This effect is unlikely to be seen in queens who are fed feline commercial diets but may be seen in situations where dog food is fed to cats. |
T62 |
12719-12759 |
Epistemic_statement |
denotes |
Dietary supplements are not recommended. |
T63 |
12760-12860 |
Epistemic_statement |
denotes |
Pregnant and nursing queens may have nutritional needs that are four times maintenance requirements. |
T64 |
12861-12974 |
Epistemic_statement |
denotes |
Canned foods may prove to be more palatable during pregnancy and should be offered if the queen's appetite wanes. |
T65 |
12975-13136 |
Epistemic_statement |
denotes |
It is possible and recommended to treat bitches to prevent transplacental and transmammary transmission of somatic Toxocara canis and Ancylostoma caninum larvae. |
T66 |
13481-13757 |
Epistemic_statement |
denotes |
The Centers for Disease Control (CDC) and the Companion Animal Parasite Council (CAPC) recommend aggressive deworming protocols of pregnant bitches, pregnant queens, and their offspring to prevent environmental contamination with parasite eggs and the potential zoonotic risk. |
T67 |
13758-13893 |
Epistemic_statement |
denotes |
A number of different protocols have been suggested using multiple doses of fenbendazole and ivermectin orally in bitches (Table 1 -3). |
T68 |
13894-14060 |
Epistemic_statement |
denotes |
In both bitches and queens, topical selamectin 6 mg/kg has been shown to greatly reduce worm burdens in both puppies (98%) and kittens (100%) up to 6 and 7 weeks old. |
T69 |
14241-14434 |
Epistemic_statement |
denotes |
Products containing carbaryl should not be used because it may cause brachygnathia, taillessness, extra digits, failure of skeletal formation, and dystocia in bitches caused by uterine inertia. |
T70 |
14435-14585 |
Epistemic_statement |
denotes |
Heartworm preventive should be continued throughout pregnancy and has been proved to have a high margin of safety even in pregnant bitches and queens. |
T71 |
15287-15458 |
Epistemic_statement |
denotes |
Serious insult during the preimplantation phase may result in an all-or-none phenomenon in which implantation does not occur or the cells survive and continue development. |
T72 |
16434-16571 |
Epistemic_statement |
denotes |
Excess vitamin D has been linked with tissue calcinosis, premature closure of fontanelles, enamel hypoplasia, and supravalvular stenosis. |
T73 |
16572-16750 |
Epistemic_statement |
denotes |
Congenital malformations can best be evaluated by careful necropsy of all nonsurviving puppies or kittens with the goal of eliminating the cause of such defects (see Chapter 31). |
T74 |
17022-17149 |
Epistemic_statement |
denotes |
Clinicians should obtain a good drug history, including the use of topical, herbal, and other alternative modalities (Box 1-6). |
T75 |
17150-17247 |
Epistemic_statement |
denotes |
The bitch should have her pregnancy confirmed 25 to 30 days after her first breeding (Table 1-4). |
T76 |
17248-17370 |
Epistemic_statement |
denotes |
In lean relaxed bitches, it may be possible to detect discrete swellings in the uterus as early as 21 days after breeding. |
T77 |
17371-17576 |
Epistemic_statement |
denotes |
However, it is not possible to use palpation to differentiate uterine swellings congenital edema involves generalized subcutaneous edema and varying amounts of fluid in other body cavities ( Figure 1-1) . |
T78 |
17577-17644 |
Epistemic_statement |
denotes |
The condition is known to be heritable likely as a recessive trait. |
T79 |
17811-17884 |
Epistemic_statement |
denotes |
Cleft palates can be caused by genetic traits or by teratogenetic agents. |
T80 |
17885-17986 |
Epistemic_statement |
denotes |
Both griseofulvin and corticosteroids have been implicated as teratogens that can cause cleft palate. |
T81 |
18046-18270 |
Epistemic_statement |
denotes |
In general, all drugs should be avoided in the pregnant bitch or queen, including all live virus vaccines, unless they are necessary to maintain the welfare of the mother and the drug is reported to be safe during pregnancy. |
T82 |
18271-18385 |
Epistemic_statement |
denotes |
associated with uterine pathology (Figures 1-4 and 1-5) from normal uterine development associated with pregnancy. |
T83 |
18507-18688 |
Epistemic_statement |
denotes |
Real-time ultrasonography is valuable in early pregnancy diagnosis, as well as throughout the second half of gestation whenever there is a question of fetal viability or fetal loss. |
T84 |
18977-19137 |
Epistemic_statement |
denotes |
If the LH peak is unknown, ultrasonography for pregnancy detection should be performed at approximately 30 days after the last known breeding (see Figure 1-4) . |
T85 |
19256-19343 |
Epistemic_statement |
denotes |
In addition to pregnancy diagnosis, ultrasonography can be used to identify fetal loss. |
T86 |
19438-19606 |
Epistemic_statement |
denotes |
This size disparity appears to be accompanied by low volume of embryonic fluid, cessation of fetal heart beat in the smaller sacs, shrinkage, and ultimately resorption. |
T87 |
19607-19680 |
Epistemic_statement |
denotes |
Ultrasound has not been proved reliable for determination of litter size. |
T88 |
19681-19854 |
Epistemic_statement |
denotes |
Determination of fetal age involves multiple measurements of the biparietal or trunk diameter and must take into consideration differences relative to breed and litter size. |
T89 |
19855-19941 |
Epistemic_statement |
denotes |
Embryonic vesicles may be detected earlier in the queen than in the bitch (Table 1-5). |
T90 |
20046-20098 |
Epistemic_statement |
denotes |
Fetal heartbeats may be detected as early as day 16. |
T91 |
20099-20220 |
Epistemic_statement |
denotes |
Embryonic vesicles closest to the uterine bifurcation are detected earliest, and early examination may miss some fetuses. |
T92 |
20221-20303 |
Epistemic_statement |
denotes |
The ultrasound should be repeated 5 to 7 days later if no fetal vesicles are seen. |
T93 |
20304-20413 |
Epistemic_statement |
denotes |
Ultrasound in the queen can be used to detect fetal loss and may be used in an attempt to estimate fetal age. |
T94 |
20467-20561 |
Epistemic_statement |
denotes |
In the bitch, progesterone elevations are not different whether a bitch is or is not pregnant. |
T95 |
20562-20633 |
Epistemic_statement |
denotes |
Progesterone levels, however, can be used to confirm ovulation failure. |
T96 |
20634-20751 |
Epistemic_statement |
denotes |
In the queen, progesterone levels may be used 40 days after breeding to differentiate pseudopregnancy from pregnancy. |
T97 |
20899-21020 |
Epistemic_statement |
denotes |
Prolactin levels increase in both the pregnant bitch and the pregnant queen; however, a commercial test is not available. |
T98 |
21368-21427 |
Epistemic_statement |
denotes |
At this visit, the physical examination should be repeated. |
T99 |
21428-21540 |
Epistemic_statement |
denotes |
The body condition of the bitch or queen should be assessed, and recommendations made for adjustments as needed. |
T100 |
21541-21678 |
Epistemic_statement |
denotes |
If the bitch or queen has previously been on a maintenance diet, she should be switched to a ration suitable for pregnancy and lactation. |
T101 |
21679-21807 |
Epistemic_statement |
denotes |
In cases where the bitch or queen is underweight and anorectic, a balanced multivitamin, such as Pet-Tabs, should be considered. |
T102 |
22004-22078 |
Epistemic_statement |
denotes |
Pregnancy may be accompanied by toxemia in bitches carrying large litters. |
T103 |
22079-22202 |
Epistemic_statement |
denotes |
Ketosis can develop in bitches not meeting the nutritional demands of pregnancy, and a negative energy balance can develop. |
T104 |
22203-22289 |
Epistemic_statement |
denotes |
Anorexia in late pregnancy must be corrected by force feeding or parenteral nutrition. |
T105 |
22290-22482 |
Epistemic_statement |
denotes |
The owner should be questioned about any changes in behavior or appetite, increases or decreases in water consumption, extent of mammary development, and the presence of any vaginal discharge. |
T106 |
22483-22610 |
Epistemic_statement |
denotes |
If the bitch or queen is found to be nonpregnant at this visit, a diagnostic workup for conception failure should be discussed. |
T107 |
22696-22866 |
Epistemic_statement |
denotes |
The bitch or queen should remain in the home, kennel, or cattery environment and should not share housing or exercise areas with animals still in competition or training. |
T108 |
22944-23042 |
Epistemic_statement |
denotes |
There are numerous viral and bacterial diseases that have potential risks for the pregnant animal. |
T109 |
23043-23173 |
Epistemic_statement |
denotes |
Training classes and competitive field events should be discontinued because the effect of stress on the bitch can be significant. |
T110 |
23368-23441 |
Epistemic_statement |
denotes |
Before term the bitch or queen should be introduced to her delivery area. |
T111 |
23442-23579 |
Epistemic_statement |
denotes |
This area should be safe and quiet and provide the privacy and comfort needed for the dam to become acclimated and ready for parturition. |
T112 |
23580-23684 |
Epistemic_statement |
denotes |
The bitch should be Figure 1-6 The lateral abdominal radiograph can be used to assess number of fetuses. |
T113 |
23685-23781 |
Epistemic_statement |
denotes |
Six puppies can be seen on this film of a Labrador retriever bitch taken 6 days before whelping. |
T114 |
23863-23940 |
Epistemic_statement |
denotes |
It can be used to assess fetal heart beats, as well as movement of the fetus. |
T115 |
24188-24349 |
Epistemic_statement |
denotes |
The bitch or queen should have a lateral abdominal radiograph (Figure 1-6 ) taken 5 to 10 days before the expected delivery date to assess the number of fetuses. |
T116 |
24350-24479 |
Epistemic_statement |
denotes |
Radiography is an accurate method for determination of fetal numbers but can underestimate the litter size in very large litters. |
T117 |
25211-25364 |
Epistemic_statement |
denotes |
During the prenatal visit, it is prudent to evaluate the dam's blood glucose and serum calcium (ionized calcium preferred) levels and packed cell volume. |
T118 |
25365-25549 |
Epistemic_statement |
denotes |
The physical examination should include a digital vaginal examination to detect any soft tissue obstructions (stricture or masses) and to evaluate the vaginal area for excessive edema. |
T119 |
25761-25957 |
Epistemic_statement |
denotes |
The client should be given verbal and written instructions on the management of parturition and should be encouraged to inform the clinician of any change in rectal temperature (Boxes 1-7 and 1-8 |
T120 |
25958-26031 |
Epistemic_statement |
denotes |
Begin preparations for delivery of puppies before the female gives birth. |
T121 |
26151-26285 |
Epistemic_statement |
denotes |
This box should be only slightly bigger than the mother, with sides 6 to 8 inches high to keep the pups from crawling out of the nest. |
T122 |
26405-26549 |
Epistemic_statement |
denotes |
Newspapers make excellent bedding because they can be changed easily, are absorbent, and can be shredded by the mother as she makes her "nest. " |
T123 |
27004-27069 |
Epistemic_statement |
denotes |
Labor in the female dog (bitch) can be divided into three stages. |
T124 |
27141-27244 |
Epistemic_statement |
denotes |
During the first stage, the mother seems extremely restless and very nervous and often seeks seclusion. |
T125 |
27245-27301 |
Epistemic_statement |
denotes |
She may refuse food even if offered her favorite treats. |
T126 |
27302-27336 |
Epistemic_statement |
denotes |
This stage may last 6 to 24 hours. |
T127 |
27696-27765 |
Epistemic_statement |
denotes |
About one-third of all puppies, however, are born hindquarters first. |
T128 |
27910-27986 |
Epistemic_statement |
denotes |
You may have to perform these functions for the mother (see Obstetric Care). |
T129 |
28233-28323 |
Epistemic_statement |
denotes |
This stage usually lasts 10 to 30 minutes, but it may range from a few seconds to an hour. |
T130 |
28538-28618 |
Epistemic_statement |
denotes |
After a few minutes of rubbing, the puppy should begin to squirm and cry loudly. |
T131 |
28619-28763 |
Epistemic_statement |
denotes |
The umbilical cord should be tied about an inch from the puppy's body with fine thread and then cut on the side of the knot away from the puppy. |
T132 |
28822-28933 |
Epistemic_statement |
denotes |
If a puppy seems to be lodged in the birth canal and the mother cannot expel it, rapid assistance is necessary. |
T133 |
28934-29007 |
Epistemic_statement |
denotes |
There may not be time to call the veterinarian and drive to the hospital. |
T134 |
29106-29163 |
Epistemic_statement |
denotes |
Traction may have to be applied for as long as 5 minutes. |
T135 |
29434-29556 |
Epistemic_statement |
denotes |
• It has been more than 3 hours since the delivery of the last pup, and it is probable that more puppies are still inside. |
T136 |
29648-29755 |
Epistemic_statement |
denotes |
The greenish-black color is normal, but the discharge should be followed very soon by delivery of the pups. |
T137 |
29988-30099 |
Epistemic_statement |
denotes |
The queen may experience a similar decrease in rectal temperature, although it is seldom reported by the owner. |
T138 |
30183-30316 |
Epistemic_statement |
denotes |
During late pregnancy, the pattern of uterine electrical activity changes, which correlates with the decrease in plasma progesterone. |
T139 |
30317-30416 |
Epistemic_statement |
denotes |
This suggests that progesterone plays an important role in the process of parturition in the bitch. |
T140 |
30417-30557 |
Epistemic_statement |
denotes |
The client should be counseled to seek veterinary attention if labor is not initiated within 24 hours of the decrease in rectal temperature. |
T141 |
30558-30723 |
Epistemic_statement |
denotes |
The client should be given after-hours contact information if the clinician will be providing after-hours care or contact information for appropriate emergency care. |