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PMC:3218875 JSONTXT 30 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue
T1382 1707-1711 Protein denotes p100
T1386 1715-1721 Protein denotes NF-κB2
T1387 1723-1727 Protein denotes p105
T1388 1731-1737 Protein denotes NF-κB1
T1389 1739-1742 Protein denotes p65
T1390 1746-1750 Protein denotes RelA
T1391 1752-1756 Protein denotes RelB
T1392 1758-1763 Protein denotes c-Rel
T1402 1823-1831 Regulation denotes regulate
T1401 1836-1846 Gene_expression denotes expression
T1393 1884-1887 Protein denotes TNF
T1383 1895-1899 Protein denotes IL-6
T1384 1901-1918 Protein denotes cyclo-oxygenase-2
T1385 1932-1963 Protein denotes inducible nitric oxide synthase
T1394 2035-2038 Protein denotes TNF
T1404 2629-2638 Positive_regulation denotes mediating
T1403 2643-2650 Regulation denotes effects
T1395 2654-2688 Protein denotes receptor activator of NF-κB ligand
T1396 2690-2695 Protein denotes RANKL
T1397 2940-2944 Protein denotes CD40
T1398 2946-2951 Protein denotes TRAF1
T1399 2953-2960 Protein denotes TNFAIP3
T1400 2966-2971 Protein denotes c-REL
T3360 3316-3319 Protein denotes TNF
T3361 3375-3378 Protein denotes TNF
T3362 3450-3453 Protein denotes TNF
T3390 3650-3660 Positive_regulation denotes activation
T3363 3664-3691 Protein denotes receptor activator of NF-κB
T3364 3693-3697 Protein denotes RANK
T3365 3789-3793 Protein denotes RANK
T3366 3903-3907 Protein denotes CD40
T3367 3919-3945 Protein denotes TNF receptor family member
T3391 3967-3976 Gene_expression denotes expressed
T3392 4146-4157 Positive_regulation denotes upregulated
T3368 4197-4200 Protein denotes TNF
T3393 4207-4214 Binding denotes Binding
T3369 4222-4233 Protein denotes CD40 ligand
T3370 4235-4240 Protein denotes CD154
T3394 4264-4273 Gene_expression denotes expressed
T3371 4302-4305 Protein denotes CD4
T3372 4576-4580 Protein denotes CD40
T3396 4756-4764 Positive_regulation denotes Enhanced
T3395 4765-4775 Gene_expression denotes expression
T3373 4810-4834 Protein denotes B-cell activating factor
T3374 4836-4840 Protein denotes BAFF
T3375 4957-4961 Protein denotes BAFF
T3376 5011-5033 Protein denotes lymphotoxin β receptor
T3377 5880-5925 Protein denotes High mobility group box chromosomal protein 1
T3378 5927-5932 Protein denotes HMGB1
T3379 5954-5973 Protein denotes chromatin component
T3397 5995-6003 Localization denotes secreted
T3398 6032-6040 Localization denotes released
T3380 6099-6111 Protein denotes TLR4 ligands
T3381 6138-6143 Protein denotes HMGB1
T3399 6147-6156 Positive_regulation denotes increased
T3382 6183-6188 Protein denotes HMGB1
T3383 6248-6253 Protein denotes HMGB1
T3384 6311-6336 Protein denotes Myeloid-related protein 8
T3385 6341-6367 Protein denotes myeloid-related protein 14
T3386 6565-6569 Protein denotes TLR4
T3400 6570-6577 Positive_regulation denotes induced
T3387 6736-6747 Protein denotes fibronectin
T3388 6749-6757 Protein denotes biglycan
T3389 6759-6769 Protein denotes tenascin C
T7084 7259-7263 Protein denotes IκBα
T7085 7265-7269 Protein denotes IκBβ
T7086 7271-7275 Protein denotes IκBε
T7087 7277-7281 Protein denotes p105
T7088 7297-7303 Protein denotes NF-κB1
T7089 7306-7310 Protein denotes p100
T7090 7326-7332 Protein denotes NF-κB2
T7091 7365-7369 Protein denotes IκBξ
T7092 7374-7379 Protein denotes Bcl-3
T7093 7437-7441 Protein denotes p100
T7094 7446-7450 Protein denotes p105
T7095 7473-7476 Protein denotes p52
T7096 7481-7484 Protein denotes p50
T7097 7808-7811 Protein denotes TNF
T7098 7830-7835 Protein denotes RANKL
T7099 8275-8279 Protein denotes IKK1
T7100 8284-8288 Protein denotes IKK2
T7101 8304-8308 Protein denotes IKKα
T7102 8313-8317 Protein denotes IKKβ
T7103 8346-8371 Protein denotes NF-κB essential modulator
T7104 8373-8377 Protein denotes NEMO
T7105 8394-8398 Protein denotes IKKγ
T7106 8451-8455 Protein denotes IKK2
T7107 8460-8464 Protein denotes NEMO
T7108 8474-8478 Protein denotes IKK1
T7195 8484-8492 Positive_regulation denotes required
T20660 8649-8654 Protein denotes TNFR1
T20669 8656-8660 Protein denotes CD40
T20670 8662-8666 Protein denotes RANK
T20671 8672-8676 Protein denotes TLR4
T20672 8731-8777 Protein denotes TNF receptor 1-associated death domain protein
T20673 8779-8784 Protein denotes TRADD
T20674 8787-8792 Protein denotes MyD88
T20675 8794-8797 Protein denotes MAL
T20676 8799-8842 Protein denotes TIR domain-containing adaptor-inducing IFNβ
T20661 8844-8848 Protein denotes TRIF
T20662 8861-8865 Protein denotes RIP1
T20663 8867-8872 Protein denotes IRAK1
T20664 8874-8879 Protein denotes IRAK4
T20665 8905-8910 Protein denotes TRAF2
T20666 8912-8917 Protein denotes TRAF6
T20667 8919-8924 Protein denotes cIAP1
T20668 8926-8931 Protein denotes cIAP2
T20716 8961-8979 Ubiquitination denotes polyubiquitination
T20677 8990-8994 Protein denotes RIP1
T20678 8999-9004 Protein denotes IRAK1
T20679 9023-9027 Protein denotes NEMO
T20717 9063-9074 Binding denotes recruitment
T20718 9079-9089 Positive_regulation denotes activation
T20680 9106-9110 Protein denotes IKK2
T20681 9115-9119 Protein denotes TAK1
T20682 9121-9125 Protein denotes TAK1
T20719 9150-9159 Positive_regulation denotes activates
T20683 9160-9164 Protein denotes IKK2
T20720 9180-9194 Phosphorylation denotes phosphorylates
T20684 9195-9199 Protein denotes IκBα
T20721 9306-9317 Binding denotes heterodimer
T20685 9321-9324 Protein denotes p65
T20686 9329-9332 Protein denotes p50
T20687 9400-9405 Protein denotes TRAF1
T20688 9534-9537 Protein denotes A20
T20689 9542-9546 Protein denotes CYLD
T20690 9658-9662 Protein denotes RIP1
T20691 9667-9672 Protein denotes TRAF6
T20722 9692-9701 Binding denotes recruited
T20692 9760-9766 Protein denotes ABIN-1
T20693 9771-9774 Protein denotes p62
T20724 9836-9846 Negative_regulation denotes inhibiting
T20723 9847-9857 Gene_expression denotes expression
T20694 9861-9866 Protein denotes IRAK1
T20695 9871-9876 Protein denotes TRAF6
T20696 9953-9959 Protein denotes SIGIRR
T20725 9988-9995 Binding denotes compete
T20697 10001-10005 Protein denotes TLR4
T20726 10010-10017 Binding denotes binding
T20698 10021-10026 Protein denotes IRAK1
T20699 10031-10036 Protein denotes TRAF6
T20700 10194-10198 Protein denotes ABIN
T20701 10200-10230 Protein denotes A20-binding inhibitor of NF-κB
T20702 10271-10275 Protein denotes CYLD
T20703 10277-10292 Protein denotes cylindromatosis
T20704 10367-10372 Protein denotes MyD88
T20705 10374-10422 Protein denotes myeloid differentiation primary response gene 88
T20706 10424-10428 Protein denotes NEMO
T20707 10430-10455 Protein denotes NF-κB essential modulator
T20708 10477-10481 Protein denotes RANK
T20709 10483-10510 Protein denotes receptor activator of NF-κB
T20710 10512-10516 Protein denotes RIP1
T20711 10518-10548 Protein denotes receptor interacting protein 1
T20712 10550-10556 Protein denotes SIGIRR
T20713 10558-10600 Protein denotes single-immunoglobulinIL-1 receptor-related
T20714 10696-10699 Protein denotes TNF
T20715 10701-10723 Protein denotes tumour necrosis factor
T7109 10782-10785 Protein denotes TNF
T7110 10795-10798 Protein denotes TNF
T7196 10826-10837 Binding denotes recruitment
T7111 10841-10879 Protein denotes TNF receptor-1-associated death domain
T7112 10881-10886 Protein denotes TRADD
T7113 10903-10933 Protein denotes receptor interacting protein 1
T7114 10935-10939 Protein denotes RIP1
T7115 11006-11045 Protein denotes TNF receptor-associated factor (TRAF) 2
T7116 11050-11055 Protein denotes TRAF5
T7197 11071-11075 Binding denotes bind
T7117 11101-11141 Protein denotes cellular inhibitor of apoptosis (cIAP) 1
T7118 11146-11151 Protein denotes cIAP2
T7119 11167-11170 Protein denotes TNF
T7198 11171-11182 Positive_regulation denotes stimulation
T7120 11203-11207 Protein denotes RIP1
T7199 11219-11227 Positive_regulation denotes modified
T7121 11264-11269 Protein denotes TRAF2
T7122 11270-11271 Protein denotes 5
T7123 11276-11281 Protein denotes cIAP1
T7124 11282-11283 Protein denotes 2
T7125 11308-11312 Protein denotes RIP1
T7200 11313-11327 Binding denotes ubiquitination
T7126 11405-11409 Protein denotes RIP1
T7201 11447-11454 Binding denotes recruit
T7127 11467-11471 Protein denotes TAK1
T7202 11488-11505 Binding denotes ubiquitin-binding
T7128 11515-11519 Protein denotes NEMO
T7129 11524-11528 Protein denotes TAB1
T7130 11529-11530 Protein denotes 2
T7131 11621-11625 Protein denotes NEMO
T7132 11680-11683 Protein denotes TNF
T7203 11893-11901 Positive_regulation denotes activate
T7133 11906-11910 Protein denotes TAK1
T7134 11994-11998 Protein denotes TLR4
T7206 12033-12040 Positive_regulation denotes induces
T7204 12045-12056 Binding denotes recruitment
T7135 12060-12094 Protein denotes Toll/IL-1 receptor adaptor protein
T7136 12116-12118 Protein denotes Ma
T7137 12125-12154 Protein denotes TRIF-related adaptor molecule
T7138 12156-12160 Protein denotes TRAM
T7205 12212-12219 Binding denotes recruit
T7139 12220-12268 Protein denotes myeloid differentiation primary response gene 88
T7140 12270-12275 Protein denotes MyD88
T7141 12281-12324 Protein denotes TIR domain-containing adaptor-inducing IFNβ
T7142 12326-12330 Protein denotes TRIF
T7143 12347-12352 Protein denotes MyD88
T7207 12361-12369 Binding denotes recruits
T7144 12427-12432 Protein denotes TRAF6
T7209 12434-12441 Positive_regulation denotes leading
T7208 12445-12460 Binding denotes oligomerisation
T7145 12487-12492 Protein denotes TRAF6
T7146 12499-12503 Protein denotes TRIF
T7210 12509-12517 Binding denotes recruits
T7147 12518-12523 Protein denotes TRAF6
T7148 12533-12537 Protein denotes RIP1
T7211 12556-12567 Binding denotes interaction
T7212 12588-12596 Positive_regulation denotes activate
T7149 12597-12601 Protein denotes TAK1
T7213 12615-12639 Regulation denotes ubiquitination-dependent
T7150 12662-12665 Protein denotes TNF
T7151 12741-12763 Protein denotes lymphotoxin β receptor
T7152 12765-12778 Protein denotes BAFF receptor
T7153 12780-12784 Protein denotes CD40
T7154 12790-12794 Protein denotes RANK
T7155 12824-12828 Protein denotes p100
T7214 12832-12841 Binding denotes processed
T7156 12863-12866 Protein denotes p52
T7157 12892-12896 Protein denotes RelB
T7158 13107-13111 Protein denotes IKK1
T7215 13122-13131 Positive_regulation denotes activated
T7159 13156-13177 Protein denotes NF-κB inducing kinase
T7160 13179-13182 Protein denotes NIK
T7161 13185-13188 Protein denotes NIK
T7216 13206-13215 Regulation denotes regulated
T7163 13330-13333 Protein denotes NIK
T7164 13371-13376 Protein denotes TRAF2
T7165 13378-13383 Protein denotes TRAF3
T7166 13389-13394 Protein denotes cIAP1
T7167 13395-13396 Protein denotes 2
T7162 13426-13429 Protein denotes NIK
T7218 13431-13438 Positive_regulation denotes leading
T7217 13457-13468 Protein_catabolism denotes degradation
T7219 13533-13539 Negative_regulation denotes remove
T7168 13540-13545 Protein denotes TRAF3
T7220 13610-13617 Binding denotes attract
T7169 13618-13623 Protein denotes TRAF2
T7170 13628-13633 Protein denotes cIAP1
T7171 13634-13635 Protein denotes 2
T7222 13647-13656 Positive_regulation denotes essential
T7172 13672-13677 Protein denotes TRAF3
T7221 13678-13689 Protein_catabolism denotes degradation
T7227 13700-13711 Positive_regulation denotes contributes
T7223 13715-13724 Localization denotes releasing
T7173 13725-13728 Protein denotes NIK
T7224 13751-13762 Protein_catabolism denotes degradation
T7228 13764-13773 Positive_regulation denotes resulting
T7174 13777-13780 Protein denotes NIK
T7225 13781-13793 Localization denotes accumulation
T7175 13798-13802 Protein denotes IKK1
T7226 13803-13818 Phosphorylation denotes phosphorylation
T22156 13880-13884 Protein denotes CD40
T22157 13889-13893 Protein denotes RANK
T22191 13946-13955 Regulation denotes dependent
T22158 13959-13980 Protein denotes NF-κB inducing kinase
T22159 13982-13985 Protein denotes NIK
T22190 13987-13997 Gene_expression denotes expression
T22162 14028-14031 Protein denotes NIK
T22163 14085-14090 Protein denotes TRAF2
T22164 14092-14097 Protein denotes TRAF3
T22165 14102-14107 Protein denotes cIAP1
T22166 14108-14109 Protein denotes 2
T22195 14117-14128 Positive_regulation denotes facilitates
T22192 14144-14162 Binding denotes polyubiquitination
T22193 14179-14190 Protein_catabolism denotes degradation
T22160 14194-14197 Protein denotes NIK
T22161 14207-14210 Protein denotes NIK
T22194 14218-14221 Positive_regulation denotes low
T22167 14244-14249 Protein denotes TRAF3
T22196 14253-14262 Binding denotes recruited
T22168 14286-14291 Protein denotes TRAF2
T22199 14292-14299 Negative_regulation denotes directs
T22197 14300-14314 Protein_catabolism denotes nondegradative
T22198 14326-14344 Positive_regulation denotes polyubiquitination
T22169 14348-14353 Protein denotes cIAP1
T22170 14354-14355 Protein denotes 2
T22171 14401-14406 Protein denotes cIAP1
T22172 14407-14408 Protein denotes 2
T22200 14432-14450 Binding denotes polyubiquitination
T22173 14454-14459 Protein denotes TRAF3
T22174 14473-14476 Protein denotes NIK
T22175 14491-14496 Protein denotes TRAF3
T22201 14500-14508 Protein_catabolism denotes degraded
T22176 14513-14516 Protein denotes NIK
T22202 14520-14530 Positive_regulation denotes stabilised
T22203 14532-14541 Positive_regulation denotes resulting
T22204 14545-14554 Positive_regulation denotes increased
T22177 14555-14558 Protein denotes NIK
T22178 14579-14582 Protein denotes NIK
T22205 14607-14616 Positive_regulation denotes activates
T22179 14617-14621 Protein denotes IKK1
T22206 14629-14637 Positive_regulation denotes mediates
T22180 14644-14648 Protein denotes p100
T22207 14649-14664 Phosphorylation denotes phosphorylation
T22208 14740-14751 Protein_catabolism denotes degradation
T22181 14755-14759 Protein denotes p100
T22182 14763-14766 Protein denotes p52
T22209 14782-14793 Binding denotes heterodimer
T22183 14799-14803 Protein denotes RelB
T22184 14839-14844 Protein denotes TRAF3
T22185 14846-14851 Protein denotes TRAF1
T22210 14891-14900 Regulation denotes regulator
T22211 15004-15013 Negative_regulation denotes inhibitor
T22186 15065-15069 Protein denotes RANK
T22187 15071-15098 Protein denotes receptor activator of NF-κB
T22188 15138-15141 Protein denotes TNF
T22189 15143-15165 Protein denotes tumour necrosis factor
T7176 15195-15199 Protein denotes CD40
T7177 15201-15223 Protein denotes lymphotoxin β receptor
T7178 15228-15232 Protein denotes RANK
T7229 15323-15330 Binding denotes binding
T7179 15348-15352 Protein denotes CD40
T7180 15357-15361 Protein denotes RANK
T7181 15408-15413 Protein denotes TRAF1
T7182 15415-15420 Protein denotes TRAF2
T7183 15422-15427 Protein denotes TRAF3
T7184 15429-15434 Protein denotes TRAF5
T7185 15440-15445 Protein denotes TRAF6
T7186 15489-15494 Protein denotes TRAF2
T7187 15499-15504 Protein denotes TRAF3
T7188 15676-15680 Protein denotes CD40
T7230 15681-15689 Positive_regulation denotes mediated
T7189 15725-15730 Protein denotes TRAF6
T7232 15734-15742 Positive_regulation denotes required
T7190 15747-15751 Protein denotes CD40
T7233 15752-15760 Positive_regulation denotes mediated
T7191 15780-15784 Protein denotes IL-6
T7231 15785-15795 Gene_expression denotes production
T7192 15803-15808 Protein denotes TRAF2
T7193 15850-15855 Protein denotes TRAF3
T7194 15890-15894 Protein denotes CD40
T9149 16895-16901 Protein denotes MyD88s
T9150 16903-16909 Protein denotes IRAK-M
T9151 16915-16921 Protein denotes TOLLIP
T9152 17069-17073 Protein denotes IKK1
T9153 17297-17301 Protein denotes IKK1
T9162 17302-17311 Negative_regulation denotes deficient
T9163 17333-17343 Gene_expression denotes expressing
T9164 17344-17352 Positive_regulation denotes inactive
T9154 17353-17357 Protein denotes IKK1
T9167 17418-17424 Positive_regulation denotes result
T9168 17428-17436 Positive_regulation denotes enhanced
T9155 17437-17441 Protein denotes IKK2
T9165 17442-17452 Positive_regulation denotes activation
T9156 17457-17461 Protein denotes IκBα
T9166 17462-17473 Protein_catabolism denotes degradation
T9158 17480-17484 Protein denotes IKK1
T9169 17580-17595 Phosphorylation denotes phosphorylating
T9157 17596-17601 Protein denotes STAT1
T9159 17660-17664 Protein denotes IKK1
T9170 17665-17679 Phosphorylation denotes phosphorylates
T9160 17680-17683 Protein denotes NIK
T9161 17781-17785 Protein denotes IKK1
T11834 17941-17944 Protein denotes A20
T11835 17953-17956 Protein denotes A20
T11836 17972-17979 Protein denotes TNFAIP3
T11837 17986-18011 Protein denotes ubiquitin-editing protein
T11838 18038-18043 Protein denotes NF-κB
T11839 18132-18135 Protein denotes TNF
T11842 18275-18278 Protein denotes A20
T11843 18382-18386 Protein denotes RIP1
T11844 18388-18392 Protein denotes RIP2
T11840 18394-18399 Protein denotes TRAF6
T11841 18404-18409 Protein denotes MALT1
T11845 18567-18572 Protein denotes Ubc13
T11846 18577-18583 Protein denotes Ubc5hc
T11847 18611-18616 Protein denotes TRAF6
T11848 18618-18623 Protein denotes TRAF2
T11849 18628-18633 Protein denotes cIAP1
T11850 18634-18635 Protein denotes 2
T11851 18691-18694 Protein denotes A20
T11896 18738-18749 Binding denotes association
T11852 18753-18756 Protein denotes A20
T11897 18766-18773 Regulation denotes targets
T11899 18774-18782 Positive_regulation denotes requires
T11898 18792-18809 Binding denotes ubiquitin-binding
T11853 18838-18877 Protein denotes A20-binding inhibitor of NF-κB (ABIN) 1
T11854 18882-18904 Protein denotes Tax1-binding protein 1
T11855 18964-18967 Protein denotes A20
T11900 18985-18994 Negative_regulation denotes inhibitor
T11856 19062-19065 Protein denotes A20
T11857 19126-19129 Protein denotes A20
T11901 19130-19139 Negative_regulation denotes deficient
T11858 19311-19314 Protein denotes A20
T11902 19315-19324 Negative_regulation denotes deficient
T11859 19360-19363 Protein denotes TNF
T11903 19475-19482 Negative_regulation denotes lacking
T11860 19483-19486 Protein denotes A20
T11861 19643-19646 Protein denotes TNF
T11862 19677-19680 Protein denotes A20
T11904 19790-19797 Negative_regulation denotes lacking
T11863 19798-19801 Protein denotes A20
T11864 19929-19932 Protein denotes A20
T11905 19933-19943 Gene_expression denotes expression
T11865 20106-20109 Protein denotes A20
T11906 20110-20120 Gene_expression denotes expression
T11907 20131-20140 Regulation denotes regulated
T11866 20168-20171 Protein denotes A20
T11867 20271-20274 Protein denotes A20
T11908 20275-20285 Gene_expression denotes expressing
T11868 20499-20502 Protein denotes A20
T11909 20503-20513 Gene_expression denotes expression
T11910 20586-20595 Negative_regulation denotes decreased
T11869 20606-20609 Protein denotes TNF
T11870 20611-20616 Protein denotes IL-1β
T11871 20618-20622 Protein denotes IL-6
T11872 20632-20637 Protein denotes RANKL
T11873 20639-20674 Protein denotes monocyte chemo-attractant protein 1
T11874 20703-20706 Protein denotes A20
T11875 20861-20864 Protein denotes TNF
T11876 20869-20874 Protein denotes IL-1β
T11911 20970-20979 Negative_regulation denotes decreased
T11877 20996-20999 Protein denotes TNF
T11878 21004-21009 Protein denotes IL-1β
T11879 21013-21016 Protein denotes A20
T11912 21017-21027 Gene_expression denotes transduced
T11880 21162-21165 Protein denotes A20
T11913 21166-21180 Positive_regulation denotes overexpression
T11881 21257-21260 Protein denotes A20
T11914 21456-21460 Negative_regulation denotes lack
T11882 21461-21464 Protein denotes A20
T11883 21607-21610 Protein denotes A20
T11915 21791-21802 Binding denotes association
T11916 21811-21820 Negative_regulation denotes mutations
T11884 21828-21831 Protein denotes A20
T11885 21982-21985 Protein denotes A20
T11886 22029-22032 Protein denotes A20
T11887 22116-22119 Protein denotes A20
T11888 22151-22154 Protein denotes TNF
T11889 22176-22179 Protein denotes TNF
T11890 22208-22216 Protein denotes cytokine
T11891 22246-22249 Protein denotes A20
T11917 22313-22319 Regulation denotes affect
T11892 22327-22330 Protein denotes A20
T11893 22507-22510 Protein denotes A20
T11919 22545-22554 Negative_regulation denotes repressed
T11894 22555-22558 Protein denotes A20
T11918 22559-22572 Transcription denotes transcription
T11895 22791-22794 Protein denotes A20
T13675 22866-22869 Protein denotes A20
T13706 22870-22877 Binding denotes binding
T13707 22878-22888 Negative_regulation denotes inhibitors
T13676 22898-22904 Protein denotes ABIN-1
T13677 22906-22912 Protein denotes ABIN-2
T13678 22917-22923 Protein denotes ABIN-3
T13679 22939-22945 Protein denotes TNIP-1
T13680 22947-22953 Protein denotes TNIP-2
T13681 22959-22965 Protein denotes TNIP-3
T13708 22999-23008 Gene_expression denotes expressed
T13682 23009-23012 Protein denotes A20
T13709 23013-23024 Binding denotes interacting
T13683 23080-23083 Protein denotes TNF
T13710 23229-23235 Binding denotes target
T13684 23236-23239 Protein denotes A20
T13685 23292-23295 Protein denotes A20
T13686 23297-23303 Protein denotes ABIN-1
T13687 23308-23314 Protein denotes ABIN-3
T13711 23315-23325 Gene_expression denotes expression
T13712 23335-23344 Regulation denotes dependent
T13688 23383-23386 Protein denotes A20
T13689 23495-23501 Protein denotes ABIN-1
T13713 23502-23511 Negative_regulation denotes deficient
T13690 23516-23522 Protein denotes ABIN-2
T13714 23523-23532 Negative_regulation denotes deficient
T13691 23707-23713 Protein denotes ABIN-3
T13715 23717-23726 Gene_expression denotes expressed
T13716 23752-23759 Gene_expression denotes express
T13692 23762-23789 Protein denotes truncated and inactive form
T13718 23790-23797 Negative_regulation denotes lacking
T13717 23810-23827 Binding denotes ubiquitin-binding
T13693 23848-23851 Protein denotes A20
T13694 23853-23859 Protein denotes ABIN-1
T13719 23874-23882 Negative_regulation denotes inhibits
T13695 23883-23886 Protein denotes TNF
T13696 23915-23921 Protein denotes ABIN-1
T13720 23922-23931 Negative_regulation denotes deficient
T13697 23962-23965 Protein denotes TNF
T13698 24048-24054 Protein denotes ABIN-1
T13699 24076-24079 Protein denotes TNF
T13700 24136-24142 Protein denotes ABIN-1
T13701 24217-24223 Protein denotes ABIN-1
T13702 24239-24242 Protein denotes A20
T13722 24468-24474 Regulation denotes depend
T13721 24482-24492 Gene_expression denotes expression
T13703 24526-24532 Protein denotes ABIN-3
T13704 24537-24540 Protein denotes A20
T13705 24679-24685 Protein denotes ABIN-1
T15072 25238-25253 Protein denotes Cylindromatosis
T15073 25262-25277 Protein denotes Cylindromatosis
T15074 25279-25283 Protein denotes CYLD
T15075 25385-25389 Protein denotes CYLD
T15080 25578-25582 Protein denotes CYLD
T15081 25588-25611 Protein denotes deubiquitinating enzyme
T15082 25674-25678 Protein denotes RANK
T15083 25807-25811 Protein denotes NEMO
T15084 25813-25818 Protein denotes TRAF2
T15076 25820-25825 Protein denotes TRAF6
T15077 25827-25832 Protein denotes TRAF7
T15078 25834-25838 Protein denotes RIP1
T15079 25843-25847 Protein denotes TAK1
T15085 25884-25887 Protein denotes A20
T15086 25933-25936 Protein denotes A20
T15087 25948-25952 Protein denotes CYLD
T15088 25985-25988 Protein denotes A20
T15106 25997-26006 Gene_expression denotes expressed
T15089 26143-26147 Protein denotes CYLD
T15090 26290-26294 Protein denotes CYLD
T15091 26333-26337 Protein denotes RANK
T15107 26406-26416 Negative_regulation denotes deficiency
T15092 26420-26424 Protein denotes CYLD
T15093 26559-26564 Protein denotes RANKL
T15094 26630-26634 Protein denotes CYLD
T15108 26635-26645 Gene_expression denotes expression
T15109 26658-26669 Positive_regulation denotes upregulated
T15095 26690-26695 Protein denotes RANKL
T15110 26730-26739 Binding denotes recruited
T15111 26743-26756 Positive_regulation denotes ubiquitinated
T15096 26757-26762 Protein denotes TRAF6
T15097 26771-26780 Protein denotes ubiquitin
T15112 26781-26788 Binding denotes binding
T15098 26805-26808 Protein denotes p62
T15099 26824-26838 Protein denotes sequestosome 1
T15100 26862-26866 Protein denotes CYLD
T15113 26876-26892 Negative_regulation denotes deubiquitination
T15101 26896-26901 Protein denotes TRAF6
T15114 26964-26974 Gene_expression denotes expressing
T15102 26993-26996 Protein denotes p62
T15103 27106-27110 Protein denotes CYLD
T15104 27135-27139 Protein denotes RANK
T15105 27244-27248 Protein denotes CYLD
T16084 27336-27379 Protein denotes Single-immunoglobulin IL-1 receptor-related
T16085 27388-27431 Protein denotes Single-immunoglobulin IL-1 receptor-related
T16086 27433-27439 Protein denotes SIGIRR
T16087 27464-27469 Protein denotes TIR-8
T16101 27553-27562 Negative_regulation denotes inhibitor
T16088 27566-27571 Protein denotes IL-1R
T16102 27616-27627 Binding denotes interaction
T16089 27650-27655 Protein denotes MyD88
T16090 27657-27662 Protein denotes IRAK1
T16091 27666-27671 Protein denotes TRAF6
T16093 27717-27722 Protein denotes IL-1R
T16092 27813-27819 Protein denotes SIGIRR
T16094 27843-27849 Protein denotes SIGIRR
T16103 27872-27882 Gene_expression denotes expression
T16104 27898-27907 Gene_expression denotes expressed
T16095 28019-28025 Protein denotes SIGIRR
T16105 28026-28040 Positive_regulation denotes overexpression
T16096 28168-28174 Protein denotes SIGIRR
T16097 28212-28218 Protein denotes SIGIRR
T16106 28219-28228 Negative_regulation denotes deficient
T16107 28391-28401 Gene_expression denotes expression
T16098 28405-28411 Protein denotes SIGIRR
T16099 28510-28516 Protein denotes SIGIRR
T16108 28520-28531 Negative_regulation denotes compromised
T16109 28574-28584 Gene_expression denotes expression
T16100 28594-28600 Protein denotes SIGIRR
T17041 28655-28687 Protein denotes TNF receptor-associated factor 1
T17042 28688-28693 Protein denotes TRAF1
T17043 28798-28807 Protein denotes ubiquitin
T17044 28862-28867 Protein denotes TRAF1
T17062 29015-29025 Gene_expression denotes Expression
T17045 29029-29034 Protein denotes TRAF1
T17063 29038-29047 Positive_regulation denotes inducible
T17046 29051-29054 Protein denotes TNF
T17064 29059-29073 Positive_regulation denotes overexpression
T17047 29077-29082 Protein denotes TRAF1
T17048 29092-29095 Protein denotes TNF
T17050 29122-29127 Protein denotes TRAF1
T17065 29128-29137 Negative_regulation denotes deficient
T17049 29170-29173 Protein denotes TNF
T17051 29251-29256 Protein denotes TRAF1
T17052 29299-29303 Protein denotes CD40
T17053 29330-29335 Protein denotes TRAF1
T17066 29336-29345 Negative_regulation denotes deficient
T17054 29426-29431 Protein denotes TRAF2
T17055 29528-29533 Protein denotes TRAF1
T17056 29595-29600 Protein denotes TRAF1
T17067 29639-29646 Binding denotes binding
T17057 29708-29713 Protein denotes TRAF1
T17068 29720-29727 Binding denotes recruit
T17058 29728-29731 Protein denotes A20
T17069 29761-29769 Binding denotes interact
T17059 29955-29960 Protein denotes TRAF1
T17060 30057-30062 Protein denotes TRAF1
T17070 30171-30182 Binding denotes association
T17061 30190-30195 Protein denotes TRAF1
T18551 30575-30583 Protein denotes miR-146a
T18552 30584-30585 Protein denotes b
T18553 30590-30597 Protein denotes miR-155
T18554 30729-30734 Protein denotes IL-1β
T18555 30736-30739 Protein denotes TNF
T18556 30771-30779 Protein denotes miR-146a
T18581 30786-30801 Regulation denotes NF-κB-dependent
T18557 30843-30848 Protein denotes IRAK1
T18558 30853-30858 Protein denotes TRAF6
T18559 30894-30902 Protein denotes miR-146a
T18560 30931-30938 Protein denotes miR-155
T18561 31006-31010 Protein denotes IKKε
T18562 31015-31019 Protein denotes RIP1
T18563 31055-31062 Protein denotes miR-155
T18582 31067-31076 Gene_expression denotes expressed
T18564 31220-31228 Protein denotes miR-146a
T18583 31237-31250 Gene_expression denotes overexpressed
T18565 31254-31257 Protein denotes CD4
T18566 31263-31268 Protein denotes IL-17
T18584 31269-31278 Gene_expression denotes producing
T18567 31364-31372 Protein denotes miR-146a
T18568 31450-31457 Protein denotes miR-155
T18585 31458-31472 Positive_regulation denotes overexpression
T18569 31651-31658 Protein denotes miR-155
T18587 31672-31679 Positive_regulation denotes promote
T18570 31680-31683 Protein denotes TNF
T18586 31684-31694 Gene_expression denotes production
T18571 31754-31761 Protein denotes miR-155
T18572 32152-32159 Protein denotes miR-155
T18573 32324-32332 Protein denotes miR-124a
T18588 32341-32350 Regulation denotes regulator
T18574 32368-32402 Protein denotes monocyte chemoattractant protein 1
T18589 32421-32430 Negative_regulation denotes decreased
T18575 32500-32507 Protein denotes miR-203
T18591 32510-32517 Positive_regulation denotes leading
T18592 32521-32530 Positive_regulation denotes increased
T18590 32531-32540 Localization denotes secretion
T18576 32544-32570 Protein denotes matrix metalloproteinase-1
T18577 32575-32579 Protein denotes IL-6
T18578 32638-32644 Protein denotes miR-16
T18579 32646-32653 Protein denotes miR-132
T18580 32659-32666 Protein denotes miR-223
T18593 32702-32712 Gene_expression denotes expression
R10051 T15088 T15106 themeOf A20,expressed
R10052 T15092 T15107 themeOf CYLD,deficiency
R10053 T15094 T15108 themeOf CYLD,expression
R10054 T15096 T15110 themeOf TRAF6,recruited
R10055 T15096 T15111 themeOf TRAF6,ubiquitinated
R10056 T15097 T15112 themeOf ubiquitin,binding
R10057 T15098 T15110 themeOf p62,recruited
R10058 T15098 T15112 themeOf p62,binding
R10059 T15101 T15113 themeOf TRAF6,deubiquitination
R10060 T15102 T15114 themeOf p62,expressing
R10061 T15108 T15109 themeOf expression,upregulated
R10677 T16085 T16102 themeOf Single-immunoglobulin IL-1 receptor-related,interaction
R10678 T16086 T16102 themeOf SIGIRR,interaction
R10679 T16087 T16102 themeOf TIR-8,interaction
R10680 T16088 T16101 themeOf IL-1R,inhibitor
R10681 T16088 T16102 themeOf IL-1R,interaction
R10682 T16088 T16102 themeOf IL-1R,interaction
R10683 T16088 T16102 themeOf IL-1R,interaction
R10684 T16089 T16101 themeOf MyD88,inhibitor
R10685 T16090 T16101 themeOf IRAK1,inhibitor
R10686 T16091 T16101 themeOf TRAF6,inhibitor
R10687 T16094 T16103 themeOf SIGIRR,expression
R10688 T16094 T16104 themeOf SIGIRR,expressed
R10689 T16095 T16105 themeOf SIGIRR,overexpression
R10690 T16097 T16106 themeOf SIGIRR,deficient
R10691 T16098 T16107 themeOf SIGIRR,expression
R10692 T16099 T16108 themeOf SIGIRR,compromised
R10693 T16100 T16109 themeOf SIGIRR,expression
R10694 T16102 T16101 themeOf interaction,inhibitor
R10695 T16102 T16101 themeOf interaction,inhibitor
R10696 T16102 T16101 themeOf interaction,inhibitor
R1113 T1382 T1402 causeOf p100,regulate
R1114 T1382 T1402 causeOf p100,regulate
R1115 T1382 T1402 causeOf p100,regulate
R1116 T1382 T1402 causeOf p100,regulate
R1117 T1383 T1401 themeOf IL-6,expression
R1118 T1384 T1401 themeOf cyclo-oxygenase-2,expression
R1119 T1385 T1401 themeOf inducible nitric oxide synthase,expression
R1120 T1393 T1401 themeOf TNF,expression
R1121 T1395 T1403 themeOf receptor activator of NF-κB ligand,effects
R1122 T1401 T1402 themeOf expression,regulate
R1123 T1401 T1402 themeOf expression,regulate
R1124 T1401 T1402 themeOf expression,regulate
R1125 T1401 T1402 themeOf expression,regulate
R1126 T1403 T1404 themeOf effects,mediating
R11292 T17045 T17062 themeOf TRAF1,Expression
R11293 T17046 T17063 causeOf TNF,inducible
R11294 T17047 T17064 themeOf TRAF1,overexpression
R11295 T17050 T17065 themeOf TRAF1,deficient
R11296 T17053 T17066 themeOf TRAF1,deficient
R11297 T17056 T17067 themeOf TRAF1,binding
R11298 T17057 T17068 themeOf TRAF1,recruit
R11299 T17058 T17068 themeOf A20,recruit
R11300 T17058 T17069 themeOf A20,interact
R11301 T17061 T17070 themeOf TRAF1,association
R11302 T17062 T17063 themeOf Expression,inducible
R12374 T18556 T18581 themeOf miR-146a,NF-κB-dependent
R12375 T18563 T18582 themeOf miR-155,expressed
R12376 T18564 T18583 themeOf miR-146a,overexpressed
R12377 T18565 T18584 themeOf CD4,producing
R12378 T18566 T18584 themeOf IL-17,producing
R12379 T18568 T18585 themeOf miR-155,overexpression
R12380 T18569 T18587 causeOf miR-155,promote
R12381 T18570 T18586 themeOf TNF,production
R12382 T18573 T18589 themeOf miR-124a,decreased
R12383 T18574 T18588 themeOf monocyte chemoattractant protein 1,regulator
R12384 T18576 T18590 themeOf matrix metalloproteinase-1,secretion
R12385 T18577 T18590 themeOf IL-6,secretion
R12386 T18578 T18593 themeOf miR-16,expression
R12387 T18579 T18593 themeOf miR-132,expression
R12388 T18580 T18593 themeOf miR-223,expression
R12389 T18586 T18587 themeOf production,promote
R12390 T18590 T18591 themeOf secretion,leading
R12391 T18590 T18592 themeOf secretion,increased
R12392 T18590 T18591 themeOf secretion,leading
R12393 T18590 T18592 themeOf secretion,increased
R13713 T20677 T20716 themeOf RIP1,polyubiquitination
R13714 T20678 T20716 themeOf IRAK1,polyubiquitination
R13715 T20680 T20717 themeOf IKK2,recruitment
R13716 T20681 T20717 themeOf TAK1,recruitment
R13717 T20682 T20719 causeOf TAK1,activates
R13718 T20683 T20719 themeOf IKK2,activates
R13719 T20683 T20720 themeOf IKK2,phosphorylates
R13720 T20684 T20720 themeOf IκBα,phosphorylates
R13721 T20685 T20721 themeOf p65,heterodimer
R13722 T20686 T20721 themeOf p50,heterodimer
R13723 T20690 T20722 themeOf RIP1,recruited
R13724 T20690 T20722 themeOf RIP1,recruited
R13725 T20691 T20722 themeOf TRAF6,recruited
R13726 T20692 T20722 themeOf ABIN-1,recruited
R13727 T20692 T20722 themeOf ABIN-1,recruited
R13728 T20693 T20722 themeOf p62,recruited
R13729 T20694 T20723 themeOf IRAK1,expression
R13730 T20695 T20723 themeOf TRAF6,expression
R13731 T20696 T20725 themeOf SIGIRR,compete
R13732 T20697 T20725 themeOf TLR4,compete
R13733 T20698 T20726 themeOf IRAK1,binding
R13734 T20699 T20726 themeOf TRAF6,binding
R13735 T20717 T20718 themeOf recruitment,activation
R13736 T20723 T20724 themeOf expression,inhibiting
R13737 T20723 T20724 themeOf expression,inhibiting
R14470 T22158 T22190 themeOf NF-κB inducing kinase,expression
R14471 T22159 T22190 themeOf NIK,expression
R14472 T22160 T22192 themeOf NIK,polyubiquitination
R14473 T22160 T22193 themeOf NIK,degradation
R14474 T22161 T22194 themeOf NIK,low
R14475 T22167 T22196 themeOf TRAF3,recruited
R14476 T22168 T22199 causeOf TRAF2,directs
R14477 T22168 T22199 causeOf TRAF2,directs
R14478 T22168 T22199 causeOf TRAF2,directs
R14479 T22168 T22199 causeOf TRAF2,directs
R14480 T22169 T22197 themeOf cIAP1,nondegradative
R14481 T22169 T22198 themeOf cIAP1,polyubiquitination
R14482 T22170 T22197 themeOf 2,nondegradative
R14483 T22170 T22198 themeOf 2,polyubiquitination
R14484 T22171 T22200 themeOf cIAP1,polyubiquitination
R14485 T22173 T22200 themeOf TRAF3,polyubiquitination
R14486 T22175 T22201 themeOf TRAF3,degraded
R14487 T22176 T22202 themeOf NIK,stabilised
R14488 T22177 T22203 themeOf NIK,resulting
R14489 T22177 T22204 themeOf NIK,increased
R14490 T22178 T22205 causeOf NIK,activates
R14491 T22179 T22205 themeOf IKK1,activates
R14492 T22179 T22206 themeOf IKK1,mediates
R14493 T22180 T22207 themeOf p100,phosphorylation
R14494 T22181 T22208 themeOf p100,degradation
R14495 T22182 T22208 themeOf p52,degradation
R14496 T22183 T22209 themeOf RelB,heterodimer
R14497 T22185 T22210 themeOf TRAF1,regulator
R14498 T22186 T22211 themeOf RANK,inhibitor
R14499 T22187 T22211 themeOf receptor activator of NF-κB,inhibitor
R14500 T22188 T22211 themeOf TNF,inhibitor
R14501 T22189 T22211 themeOf tumour necrosis factor,inhibitor
R14502 T22190 T22191 themeOf expression,dependent
R14503 T22190 T22191 themeOf expression,dependent
R14504 T22192 T22195 themeOf polyubiquitination,facilitates
R14505 T22193 T22195 themeOf degradation,facilitates
R14506 T22197 T22198 themeOf nondegradative,polyubiquitination
R14507 T22197 T22198 themeOf nondegradative,polyubiquitination
R14508 T22198 T22199 themeOf polyubiquitination,directs
R14509 T22198 T22199 themeOf polyubiquitination,directs
R14510 T22198 T22199 themeOf polyubiquitination,directs
R14511 T22198 T22199 themeOf polyubiquitination,directs
R14512 T22204 T22203 themeOf increased,resulting
R14513 T22207 T22206 themeOf phosphorylation,mediates
R2683 T3363 T3390 themeOf receptor activator of NF-κB,activation
R2684 T3366 T3391 themeOf CD40,expressed
R2685 T3367 T3392 themeOf TNF receptor family member,upregulated
R2686 T3367 T3391 themeOf TNF receptor family member,expressed
R2687 T3369 T3393 themeOf CD40 ligand,Binding
R2688 T3370 T3393 themeOf CD154,Binding
R2689 T3370 T3394 themeOf CD154,expressed
R2691 T3373 T3395 themeOf B-cell activating factor,expression
R2692 T3374 T3395 themeOf BAFF,expression
R2695 T3379 T3397 themeOf chromatin component,secreted
R2696 T3379 T3398 themeOf chromatin component,released
R2697 T3381 T3399 themeOf HMGB1,increased
R2700 T3386 T3400 themeOf TLR4,induced
R2705 T3395 T3396 themeOf expression,Enhanced
R2706 T3395 T3396 themeOf expression,Enhanced
R4973 T7106 T7195 themeOf IKK2,required
R4974 T7107 T7195 themeOf NEMO,required
R4975 T7108 T7195 causeOf IKK1,required
R4976 T7108 T7195 causeOf IKK1,required
R4978 T7111 T7196 themeOf TNF receptor-1-associated death domain,recruitment
R4979 T7112 T7196 themeOf TRADD,recruitment
R4980 T7112 T7196 themeOf TRADD,recruitment
R4981 T7113 T7196 themeOf receptor interacting protein 1,recruitment
R4982 T7113 T7197 themeOf receptor interacting protein 1,bind
R4983 T7113 T7196 themeOf receptor interacting protein 1,recruitment
R4984 T7113 T7197 themeOf receptor interacting protein 1,bind
R4985 T7113 T7197 themeOf receptor interacting protein 1,bind
R4987 T7114 T7196 themeOf RIP1,recruitment
R4988 T7114 T7197 themeOf RIP1,bind
R4989 T7114 T7197 themeOf RIP1,bind
R4990 T7114 T7197 themeOf RIP1,bind
R4991 T7115 T7197 themeOf TNF receptor-associated factor (TRAF) 2,bind
R4992 T7115 T7197 themeOf TNF receptor-associated factor (TRAF) 2,bind
R4993 T7116 T7197 themeOf TRAF5,bind
R4994 T7116 T7197 themeOf TRAF5,bind
R4995 T7116 T7197 themeOf TRAF5,bind
R4996 T7116 T7197 themeOf TRAF5,bind
R4997 T7117 T7197 themeOf cellular inhibitor of apoptosis (cIAP) 1,bind
R4998 T7117 T7197 themeOf cellular inhibitor of apoptosis (cIAP) 1,bind
R4999 T7117 T7197 themeOf cellular inhibitor of apoptosis (cIAP) 1,bind
R5000 T7117 T7197 themeOf cellular inhibitor of apoptosis (cIAP) 1,bind
R5001 T7118 T7197 themeOf cIAP2,bind
R5002 T7118 T7197 themeOf cIAP2,bind
R5003 T7118 T7197 themeOf cIAP2,bind
R5004 T7118 T7197 themeOf cIAP2,bind
R5005 T7119 T7198 themeOf TNF,stimulation
R5006 T7120 T7199 themeOf RIP1,modified
R5007 T7121 T7200 themeOf TRAF2,ubiquitination
R5009 T7123 T7200 themeOf cIAP1,ubiquitination
R5010 T7125 T7200 themeOf RIP1,ubiquitination
R5011 T7125 T7200 themeOf RIP1,ubiquitination
R5012 T7127 T7201 themeOf TAK1,recruit
R5013 T7127 T7201 themeOf TAK1,recruit
R5014 T7127 T7201 themeOf TAK1,recruit
R5015 T7128 T7201 themeOf NEMO,recruit
R5016 T7128 T7202 themeOf NEMO,ubiquitin-binding
R5017 T7128 T7202 themeOf NEMO,ubiquitin-binding
R5018 T7129 T7202 themeOf TAB1,ubiquitin-binding
R5019 T7129 T7201 themeOf TAB1,recruit
R5020 T7129 T7202 themeOf TAB1,ubiquitin-binding
R5021 T7130 T7201 themeOf 2,recruit
R5022 T7130 T7202 themeOf 2,ubiquitin-binding
R5023 T7130 T7202 themeOf 2,ubiquitin-binding
R5024 T7133 T7203 themeOf TAK1,activate
R5025 T7135 T7204 themeOf Toll/IL-1 receptor adaptor protein,recruitment
R5026 T7135 T7205 themeOf Toll/IL-1 receptor adaptor protein,recruit
R5027 T7135 T7204 themeOf Toll/IL-1 receptor adaptor protein,recruitment
R5028 T7135 T7205 themeOf Toll/IL-1 receptor adaptor protein,recruit
R5029 T7135 T7205 themeOf Toll/IL-1 receptor adaptor protein,recruit
R5030 T7135 T7205 themeOf Toll/IL-1 receptor adaptor protein,recruit
R5032 T7137 T7204 themeOf TRIF-related adaptor molecule,recruitment
R5033 T7137 T7204 themeOf TRIF-related adaptor molecule,recruitment
R5034 T7137 T7205 themeOf TRIF-related adaptor molecule,recruit
R5035 T7137 T7205 themeOf TRIF-related adaptor molecule,recruit
R5036 T7138 T7204 themeOf TRAM,recruitment
R5037 T7138 T7204 themeOf TRAM,recruitment
R5040 T7138 T7205 themeOf TRAM,recruit
R5041 T7138 T7205 themeOf TRAM,recruit
R5042 T7139 T7205 themeOf myeloid differentiation primary response gene 88,recruit
R5043 T7140 T7205 themeOf MyD88,recruit
R5044 T7141 T7205 themeOf TIR domain-containing adaptor-inducing IFNβ,recruit
R5045 T7141 T7205 themeOf TIR domain-containing adaptor-inducing IFNβ,recruit
R5046 T7141 T7205 themeOf TIR domain-containing adaptor-inducing IFNβ,recruit
R5047 T7142 T7205 themeOf TRIF,recruit
R5048 T7142 T7205 themeOf TRIF,recruit
R5049 T7142 T7205 themeOf TRIF,recruit
R5053 T7143 T7207 themeOf MyD88,recruits
R5054 T7144 T7207 themeOf TRAF6,recruits
R5055 T7145 T7208 themeOf TRAF6,oligomerisation
R5056 T7146 T7210 themeOf TRIF,recruits
R5057 T7146 T7211 themeOf TRIF,interaction
R5058 T7146 T7210 themeOf TRIF,recruits
R5059 T7146 T7211 themeOf TRIF,interaction
R5060 T7147 T7210 themeOf TRAF6,recruits
R5061 T7147 T7211 themeOf TRAF6,interaction
R5062 T7147 T7211 themeOf TRAF6,interaction
R5063 T7148 T7210 themeOf RIP1,recruits
R5064 T7148 T7211 themeOf RIP1,interaction
R5065 T7148 T7211 themeOf RIP1,interaction
R5066 T7149 T7212 themeOf TAK1,activate
R5068 T7155 T7214 themeOf p100,processed
R5069 T7156 T7214 themeOf p52,processed
R5070 T7158 T7215 themeOf IKK1,activated
R5071 T7159 T7215 causeOf NF-κB inducing kinase,activated
R5073 T7161 T7216 themeOf NIK,regulated
R5074 T7163 T7217 themeOf NIK,degradation
R5077 T7167 T7217 themeOf 2,degradation
R5078 T7168 T7219 themeOf TRAF3,remove
R5079 T7169 T7220 themeOf TRAF2,attract
R5080 T7169 T7222 causeOf TRAF2,essential
R5081 T7169 T7220 themeOf TRAF2,attract
R5082 T7170 T7220 themeOf cIAP1,attract
R5083 T7170 T7220 themeOf cIAP1,attract
R5084 T7170 T7222 causeOf cIAP1,essential
R5085 T7171 T7220 themeOf 2,attract
R5086 T7171 T7220 themeOf 2,attract
R5087 T7171 T7222 causeOf 2,essential
R5088 T7208 T7209 themeOf oligomerisation,leading
R5089 T7172 T7221 themeOf TRAF3,degradation
R5090 T7173 T7223 themeOf NIK,releasing
R5091 T7173 T7224 themeOf NIK,degradation
R5092 T7174 T7225 themeOf NIK,accumulation
R5093 T7175 T7226 themeOf IKK1,phosphorylation
R5094 T7212 T7213 themeOf activate,ubiquitination-dependent
R5095 T7179 T7229 themeOf CD40,binding
R5096 T7182 T7229 themeOf TRAF2,binding
R5097 T7217 T7218 themeOf degradation,leading
R5098 T7188 T7230 themeOf CD40,mediated
R5099 T7189 T7232 causeOf TRAF6,required
R5100 T7190 T7233 causeOf CD40,mediated
R5101 T7191 T7231 themeOf IL-6,production
R5102 T7217 T7218 themeOf degradation,leading
R5103 T7221 T7222 themeOf degradation,essential
R5104 T7198 T7199 themeOf stimulation,modified
R5105 T7221 T7222 themeOf degradation,essential
R5106 T7221 T7222 themeOf degradation,essential
R5107 T7204 T7206 themeOf recruitment,induces
R5108 T7204 T7206 themeOf recruitment,induces
R5109 T7204 T7206 themeOf recruitment,induces
R5110 T7223 T7227 themeOf releasing,contributes
R5111 T7225 T7228 themeOf accumulation,resulting
R5112 T7226 T7228 themeOf phosphorylation,resulting
R5113 T7231 T7232 themeOf production,required
R5114 T7231 T7233 themeOf production,mediated
R6255 T9153 T9162 themeOf IKK1,deficient
R6256 T9154 T9163 themeOf IKK1,expressing
R6257 T9154 T9164 themeOf IKK1,inactive
R6258 T9155 T9165 themeOf IKK2,activation
R6259 T9156 T9166 themeOf IκBα,degradation
R6260 T9157 T9169 themeOf STAT1,phosphorylating
R6261 T9159 T9170 causeOf IKK1,phosphorylates
R6262 T9160 T9170 themeOf NIK,phosphorylates
R6263 T9165 T9167 themeOf activation,result
R6264 T9165 T9168 themeOf activation,enhanced
R6265 T9166 T9167 themeOf degradation,result
R8100 T11852 T11896 themeOf A20,association
R8102 T11884 T11915 themeOf A20,association
R8103 T11884 T11916 themeOf A20,mutations
R8104 T11853 T11898 themeOf A20-binding inhibitor of NF-κB (ABIN) 1,ubiquitin-binding
R8105 T11853 T11899 causeOf A20-binding inhibitor of NF-κB (ABIN) 1,requires
R8106 T11854 T11898 themeOf Tax1-binding protein 1,ubiquitin-binding
R8107 T11855 T11900 themeOf A20,inhibitor
R8108 T11892 T11917 themeOf A20,affect
R8109 T11894 T11918 themeOf A20,transcription
R8110 T11857 T11901 themeOf A20,deficient
R8111 T11896 T11897 themeOf association,targets
R8112 T11858 T11902 themeOf A20,deficient
R8113 T11898 T11899 themeOf ubiquitin-binding,requires
R8114 T11860 T11903 themeOf A20,lacking
R8115 T11863 T11904 themeOf A20,lacking
R8116 T11906 T11907 themeOf expression,regulated
R8117 T11864 T11905 themeOf A20,expression
R8118 T11865 T11906 themeOf A20,expression
R8119 T11867 T11908 themeOf A20,expressing
R8120 T11915 T11916 themeOf association,mutations
R8121 T11868 T11909 themeOf A20,expression
R8122 T11918 T11919 themeOf transcription,repressed
R8123 T11869 T11910 themeOf TNF,decreased
R8124 T11870 T11910 themeOf IL-1β,decreased
R8125 T11871 T11910 themeOf IL-6,decreased
R8126 T11872 T11910 themeOf RANKL,decreased
R8127 T11873 T11910 themeOf monocyte chemo-attractant protein 1,decreased
R8128 T11877 T11911 themeOf TNF,decreased
R8129 T11878 T11911 themeOf IL-1β,decreased
R8130 T11879 T11912 themeOf A20,transduced
R8132 T11880 T11913 themeOf A20,overexpression
R8137 T11882 T11914 themeOf A20,lack
R9177 T13675 T13706 themeOf A20,binding
R9178 T13677 T13709 themeOf ABIN-2,interacting
R9179 T13678 T13709 themeOf ABIN-3,interacting
R9180 T13682 T13708 themeOf A20,expressed
R9181 T13682 T13709 themeOf A20,interacting
R9182 T13682 T13709 themeOf A20,interacting
R9183 T13684 T13710 themeOf A20,target
R9184 T13685 T13712 causeOf A20,dependent
R9185 T13685 T13712 causeOf A20,dependent
R9186 T13686 T13711 themeOf ABIN-1,expression
R9187 T13686 T13712 causeOf ABIN-1,dependent
R9188 T13686 T13712 causeOf ABIN-1,dependent
R9189 T13687 T13711 themeOf ABIN-3,expression
R9190 T13689 T13713 themeOf ABIN-1,deficient
R9191 T13690 T13714 themeOf ABIN-2,deficient
R9192 T13691 T13715 themeOf ABIN-3,expressed
R9193 T13691 T13717 themeOf ABIN-3,ubiquitin-binding
R9194 T13692 T13716 themeOf truncated and inactive form,express
R9195 T13692 T13717 themeOf truncated and inactive form,ubiquitin-binding
R9196 T13693 T13719 themeOf A20,inhibits
R9197 T13694 T13719 causeOf ABIN-1,inhibits
R9198 T13696 T13720 themeOf ABIN-1,deficient
R9199 T13703 T13721 themeOf ABIN-3,expression
R9200 T13704 T13721 themeOf A20,expression
R9201 T13706 T13707 themeOf binding,inhibitors
R9202 T13711 T13712 themeOf expression,dependent
R9203 T13711 T13712 themeOf expression,dependent
R9204 T13711 T13712 themeOf expression,dependent
R9205 T13711 T13712 themeOf expression,dependent
R9206 T13717 T13718 themeOf ubiquitin-binding,lacking
R9207 T13721 T13722 themeOf expression,depend
R9208 T13721 T13722 themeOf expression,depend