Covid19_manual_annotation  

PubMed:32807241 JSONTXT 22 Projects

Annnotations TAB TSV DIC JSON TextAE

Id Subject Object Predicate Lexical cue ForCovid19 correct word correct/standard/original word details tao:has_database_id typo
T142 0-12 TrialDesign denotes Multi-centre
T143 14-23 TrialDesign denotes three arm
T144 25-46 TrialDesign denotes randomized controlled
6 67-85 Chemical denotes methylprednisolone drug MESH:D008775
7 90-112 Chemical denotes unfractionated heparin drug MESH:D006493
T64 116-130 Severity denotes critically ill
T145 131-141 Therapy denotes ventilated
9 142-150 Species denotes patients Tax:9606
10 156-165 Disease denotes pneumonia MESH:D011014
11 171-181 Disease denotes SARS-CoV-2 MESH:D000086382
T147 182-191 Disease denotes infection MESH:MESH:D007239
T146 240-261 TrialDesign denotes randomised controlled
T151 314-324 Type denotes adjunctive
T150 325-332 Therapy denotes therapy
T152 325-332 Therapy denotes therapy
T155 325-332 Therapy denotes therapy
122 338-356 Chemical denotes methylprednisolone drug MESH:D008775
123 361-383 Chemical denotes unfractionated heparin drug MESH:D006493
124 385-388 Chemical denotes UFH drug MESH:D006493
125 398-416 Chemical denotes methylprednisolone drug MESH:D008775
126 421-449 Chemical denotes low molecular weight heparin drug MESH:D006495
127 451-455 Chemical denotes LMWH drug MESH:D006495
T154 461-465 PositiveRegulation denotes more
T153 479-487 Decrease denotes reducing
128 498-507 Die denotes mortality MESH:D009026
T65 511-525 Severity denotes critically-ill
T149 526-536 Therapy denotes ventilated
130 537-545 Species denotes patients Tax:9606
131 551-560 Disease denotes pneumonia MESH:D011014
132 566-576 Disease denotes SARS-CoV-2 MESH:D000086382
T148 577-586 Disease denotes infection MESH:MESH:D007239
133 599-603 Chemical denotes LMWH drug MESH:D006495
T156 652-664 TrialDesign denotes multi-centre
T157 666-680 TrialDesign denotes interventional
T158 682-696 TrialDesign denotes parallel group
T159 698-709 TrialDesign denotes superiority
T160 711-721 TrialDesign denotes randomized
T161 723-745 TrialDesign denotes investigator sponsored
T162 747-757 TrialDesign denotes three arms
134 765-773 Species denotes Patients Tax:9606
T163 845-853 TrialDesign denotes randomly
T165 911-916 Ratio denotes 1:1:1
135 918-930 Species denotes PARTICIPANTS Tax:9606
T69 968-975 Area denotes Italian
136 1070-1080 Species denotes SARS-CoV-2 Tax:2697049
T166 1096-1111 Method denotes pharyngeal swab
T167 1115-1136 Biological denotes deep airways material
T70 1150-1170 Therapy denotes pressure ventilation trial criteria
T71 1179-1191 Type denotes non-invasive trial criteria
T75 1195-1203 Type denotes invasive trial criteria
T84 1210-1220 Period denotes > 24 hours trial criteria
T169 1224-1232 Type denotes Invasive trial criteria
T168 1233-1243 Type denotes mechanical trial criteria
T85 1244-1255 Therapy denotes ventilation trial criteria
T86 1261-1271 Period denotes < 96 hours trial criteria
T89 1275-1290 Index denotes PaO2/FiO2 ratio trial criteria
T87 1291-1310 Value denotes lower than 150 mmHg trial criteria
T68 1314-1321 Index denotes D-dimer trial criteria MESH:C036309
T88 1328-1337 Times denotes > 6 times trial criteria
T170 1338-1379 Value denotes the upper limit of normal reference range trial criteria
137 1383-1401 Gene denotes C-reactive Protein trial criteria Gene:1401
T90 1402-1410 Detail denotes > 6-fold trial criteria
T171 1411-1452 Value denotes upper the limit of normal reference range trial criteria
T135 1480-1490 Age denotes < 18 years trial criteria|exclude
T92 1503-1512 Therapy denotes treatment exclude
T174 1518-1537 Chemical denotes anticoagulant drugs notCovid19|drug
T136 1541-1549 Biological denotes Platelet trial criteria|exclude
T172 1550-1555 Number denotes count trial criteria|exclude
T137 1556-1569 Value denotes < 100.000/mm3 trial criteria|exclude
138 1584-1591 Chemical denotes heparin MESH:D006493
T173 1592-1599 Induce denotes induced
T140 1600-1616 Disease denotes thrombocytopenia history|exclude MESH:D013921
T96 1620-1627 Disease denotes Allergy exclude http://purl.obolibrary.org/obo/HP_0012393
140 1631-1648 Chemical denotes sodium enoxaparin
141 1658-1662 Chemical denotes LMWH MESH:D006495
142 1664-1667 Chemical denotes UFH MESH:D006493
143 1671-1689 Chemical denotes methylprednisolone MESH:D008775
T98 1693-1699 Condition denotes Active exclude
144 1700-1708 Disease denotes bleeding exclude MESH:D006470
T176 1750-1759 BecomeSevere denotes high risk
145 1763-1771 Disease denotes bleeding exclude MESH:D006470
T175 1772-1788 Negative denotes contraindicating
T97 1789-1812 Therapy denotes anticoagulant treatment exclude
T177 1831-1843 Period denotes last 1 month
T100 1868-1873 Biological denotes brain
T101 1875-1881 Biological denotes spinal
T102 1885-1895 Biological denotes ophthalmic
T99 1896-1903 Therapy denotes surgery exclude
T105 1907-1914 Therapy denotes Chronic exclude
T104 1929-1949 Chemical denotes oral corticosteroids exclude|drug
T178 1934-1949 Therapy denotes corticosteroids exclude
T106 1953-1962 Condition denotes Pregnancy exclude
T107 1966-1979 Condition denotes breastfeeding exclude
T179 1983-1991 Positive denotes positive
T108 1992-2006 Method denotes pregnancy test exclude
146 2028-2033 Species denotes women exclude Tax:9606
T109 2055-2069 Method denotes pregnancy test exclude
T180 2139-2154 Status_of_Care denotes life-sustaining
T110 2155-2164 Therapy denotes treatment exclude
T111 2169-2177 Condition denotes too sick exclude
T181 2212-2218 Severity denotes severe
T112 2219-2227 Disease denotes diseases exclude
147 2260-2268 Species denotes patients Tax:9606
T182 2423-2433 TrialDesign denotes LMWH group
149 2435-2443 Species denotes patients Tax:9606
150 2479-2489 Chemical denotes enoxaparin drug MESH:D017984
T3 2493-2521 Dose denotes standard prophylactic dosage
T188 2525-2545 TrialDesign denotes LMWH + steroid group
153 2547-2555 Species denotes patients Tax:9606
154 2583-2593 Chemical denotes enoxaparin drug MESH:D017984
T4 2597-2625 Dose denotes standard prophylactic dosage
155 2630-2648 Chemical denotes methylprednisolone drug MESH:D008775
T191 2652-2671 Chemical denotes UFH + steroid group
158 2673-2681 Species denotes patients Tax:9606
159 2709-2712 Chemical denotes UFH drug MESH:D006493
T5 2716-2735 Dose denotes therapeutic dosages
160 2740-2758 Chemical denotes methylprednisolone drug MESH:D008775
161 2760-2763 Chemical denotes UFH drug MESH:D006493
T7 2772-2784 Method denotes administered
T193 2785-2798 Biological denotes intravenously
T192 2802-2821 Chemical denotes UFH + steroid group
T6 2825-2842 Dose denotes therapeutic doses
T194 2879-2892 Index denotes infusion rate
T8 2896-2909 Amount denotes 18 UI/kg/hour
T196 2919-2927 Change denotes modified
T9 2938-2948 Index denotes aPTT Ratio
T195 2973-2980 Ratio denotes 1.5-2.0
T197 3029-3052 Interval denotes no longer than 12 hours
164 3073-3076 Chemical denotes UFH drug MESH:D006493
T10 3098-3117 Period denotes up to ICU discharge
T201 3119-3138 Timing denotes After ICU discharge
T198 3139-3160 Therapy denotes anticoagulant therapy
T199 3168-3179 Interrupt denotes interrupted
T200 3183-3191 Change denotes switched
165 3212-3216 Chemical denotes LMWH drug MESH:D006495
166 3294-3304 Chemical denotes Enoxaparin drug MESH:D017984
T183 3334-3344 TrialDesign denotes LMWH group
T189 3349-3369 TrialDesign denotes LMWH + steroid group
T11 3373-3399 Dose denotes standard prophylactic dose
T204 3373-3399 Dose denotes standard prophylactic dose
T125 3407-3414 Amount denotes 4000 UI
T126 3415-3423 Interval denotes once day
T124 3438-3445 Amount denotes 6000 UI
T127 3446-3454 Interval denotes once day
170 3459-3467 Species denotes patients Tax:9606
T203 3468-3477 Index denotes weighting
T202 3478-3493 Value denotes more than 90 kg
T14 3518-3530 Method denotes administered
T205 3531-3545 Biological denotes subcutaneously
T15 3546-3556 Interval denotes once a day
T13 3557-3576 Period denotes up to ICU discharge
171 3710-3728 Chemical denotes Methylprednisolone drug MESH:D008775
T210 3737-3749 Dose denotes administered
T211 3737-3749 Dose denotes administered
T212 3737-3749 Dose denotes administered
T213 3737-3749 Dose denotes administered
T190 3758-3778 TrialDesign denotes LMWH + steroid group
T206 3783-3802 TrialDesign denotes UHF + steroid group UFH + steroid group t
T16 3803-3816 Method denotes intravenously
T17 3825-3838 Timing denotes initial bolus
T209 3842-3851 Amount denotes 0,5 mg/kg
T131 3882-3891 Amount denotes 0,5 mg/kg
T18 3892-3905 Interval denotes 4 times daily
T19 3906-3916 Timing denotes for 7 days
T132 3918-3927 Amount denotes 0,5 mg/kg
T21 3928-3941 Interval denotes 3 times daily
T22 3942-3962 Timing denotes from day 8 to day 10
T133 3964-3973 Amount denotes 0,5 mg/kg
T24 3974-3987 Interval denotes 2 times daily
T25 3988-4005 Timing denotes at days 11 and 12
T134 4010-4019 Amount denotes 0,5 mg/kg
T27 4020-4030 Interval denotes once daily
T28 4031-4048 Timing denotes at days 13 and 14
176 4102-4111 Die denotes mortality MESH:D009026
T113 4154-4165 Therapy denotes Ventilation
T214 4166-4170 Prevent denotes free
178 4235-4242 Species denotes patient Tax:9606
T216 4256-4260 Prevent denotes free
T115 4264-4275 Therapy denotes ventilation
T77 4284-4292 Type denotes invasive
T72 4296-4308 Type denotes non-invasive
T217 4394-4408 Chemical denotes administration
T31 4412-4421 Amount denotes high-dose
179 4422-4430 Chemical denotes steroids drug MESH:D013256
T30 4434-4457 Chemical denotes immune-modulatory drugs drug
T73 4487-4499 Type denotes non-invasive
T219 4503-4522 Type denotes invasive mechanical
T116 4512-4522 Type denotes mechanical
T218 4523-4534 Therapy denotes ventilation
T221 4574-4586 Type denotes non-invasive
T74 4587-4598 Therapy denotes ventilation
T220 4612-4620 Type denotes invasive
T82 4621-4632 Therapy denotes ventilation
180 4646-4655 Die denotes mortality MESH:D009026
182 4821-4831 Disease denotes infections MESH:D007239
183 4872-4882 Disease denotes infections MESH:D007239
T34 4886-4893 Species denotes Candida Tax:1535326
T35 4886-4893 Species denotes Candida Tax:5475
T37 4895-4906 Species denotes Aspergillus Tax:5052
184 4908-4918 Species denotes Adenovirus Tax:10508
T38 4920-4950 Species denotes Herpes Virus e Cytomegalovirus
185 4971-4988 Disease denotes organ dysfunction
186 5055-5077 Disease denotes venous thromboembolism MESH:D054556
187 5079-5085 Disease denotes stroke MESH:D020521
188 5089-5110 Disease denotes myocardial infarction MESH:D009203
189 5152-5160 Disease denotes bleeding MESH:D006470
T41 5173-5184 Method denotes transfusion
T43 5188-5213 Amount denotes 2 or more units of packed
T44 5214-5229 Biological denotes red blood cells
T42 5230-5238 Timing denotes in a day
190 5240-5248 Disease denotes bleeding MESH:D020300
T121 5240-5248 Disease denotes bleeding
T45 5310-5322 Disease denotes intracranial
T46 5324-5336 Biological denotes intra-spinal
191 5338-5349 Biological denotes intraocular
T122 5376-5379 Biological denotes eye
T123 5389-5407 Disease denotes conjunctival bleed
T222 5411-5414 Negative denotes not
T49 5438-5449 Biological denotes pericardial
T51 5451-5466 Biological denotes intra-articular
T52 5468-5481 Biological denotes intramuscular
194 5487-5507 Disease denotes compartment syndrome MESH:D003161
T119 5499-5507 Disease denotes syndrome
T120 5512-5527 Biological denotes retroperitoneal
195 5530-5538 Disease denotes bleeding
T55 5557-5578 Therapy denotes surgical intervention
196 5583-5591 Disease denotes bleeding lethal
197 5620-5628 Disease denotes bleeding MESH:D006470
198 5665-5670 Die denotes death MESH:D003643
199 5698-5703 Die denotes death MESH:D003643
200 5742-5760 Disease denotes non-major bleeding
201 5773-5804 Disease denotes acute clinically overt bleeding
202 5867-5900 Disease denotes bleeding compromising hemodynamic
203 5902-5922 Disease denotes spontaneous hematoma HP:0007420
T57 5923-5941 Detail denotes larger than 25 cm2
204 5943-5965 Disease denotes intramuscular hematoma HP:0012233
205 5997-6007 Disease denotes haematuria MESH:D006417
T59 6109-6120 Disease denotes haemoptysis Hemoptysis synonym MESH:D006469
206 6122-6133 Disease denotes hematemesis MESH:D006396
207 6137-6164 Disease denotes spontaneous rectal bleeding
208 6218-6236 Disease denotes any other bleeding
T60 6247-6282 Disease denotes temporary cessation of a study drug
209 6698-6710 Species denotes Participants Tax:9606
T61 6876-6879 Chemical denotes UHF drug UFH MESH:D006493 t
211 6884-6891 Chemical denotes steroid drug MESH:D013256
T184 6903-6913 TrialDesign denotes LMWH group
213 6952-6957 Die denotes death MESH:D003643
214 7068-7076 Species denotes patients Tax:9606
215 7135-7144 Die denotes mortality MESH:D009026
T185 7153-7163 TrialDesign denotes LMWH group
217 7213-7221 Species denotes patients Tax:9606
218 7316-7321 Die denotes death MESH:D003643
219 7341-7348 Chemical denotes steroid MESH:D013256
T186 7359-7369 TrialDesign denotes LMWH group
T207 7376-7395 TrialDesign denotes UHF + steroid group UFH + steroid group t
T187 7400-7410 TrialDesign denotes LMWH group
224 7474-7478 Chemical denotes LMHW
225 7481-7488 Chemical denotes steroid MESH:D013256
T208 7499-7518 TrialDesign denotes UHF + steroid group UFH + steroid group t
228 7781-7789 Species denotes patients Tax:9606
229 7815-7823 Species denotes patients Tax:9606
230 7863-7871 Species denotes patients Tax:9606
T141 7901-7904 Number denotes 210 trial criteria
231 7905-7917 Species denotes participants Tax:9606
R100 125 T152 using methylprednisolone,therapy
R101 126 T152 using low molecular weight heparin,therapy
R102 T152 T154 is_a therapy,more
R103 T150 T154 is_a therapy,more
R104 T154 T153 is_a more,reducing
R105 T153 128 is_a reducing,mortality
R106 128 130 is_a mortality,patients
R107 T151 T152 of_a adjunctive,therapy
R108 T151 T155 of_a adjunctive,therapy
R109 133 T155 using LMWH,therapy
R110 T155 T154 against therapy,more
R111 T165 T163 of_a 1:1:1,randomly
R112 T84 T70 in > 24 hours,pressure ventilation
R113 T71 T70 of_a non-invasive,pressure ventilation
R114 T75 T70 of_a invasive,pressure ventilation
R115 T167 T166 of_a deep airways material,pharyngeal swab
R116 T169 T85 of_a Invasive,ventilation
R119 T86 T85 in < 96 hours,ventilation
R120 T170 T88 of_a the upper limit of normal reference range,> 6 times
R121 T171 T90 of_a upper the limit of normal reference range,> 6-fold
R122 T172 T137 of_a count,< 100.000/mm3
R123 T136 T172 of_a Platelet,count
R124 T173 T140 is_a induced,thrombocytopenia
R125 138 T173 is_a heparin,induced
R126 T96 140 to Allergy,sodium enoxaparin
R127 T96 141 to Allergy,LMWH
R128 T96 142 to Allergy,UFH
R129 T96 143 to Allergy,methylprednisolone
R130 T174 T92 using anticoagulant drugs,treatment
R131 T98 144 of_a Active,bleeding
R132 T175 T97 is_a contraindicating,anticoagulant treatment
R133 T176 145 is_a high risk,bleeding
R134 T97 T176 is_a anticoagulant treatment,high risk
R135 T177 T99 in last 1 month,surgery
R136 T105 T178 - Chronic,corticosteroids
R137 T108 T179 using pregnancy test,positive
R138 T109 146 has_a pregnancy test,women
R139 T110 T180 has_status treatment,life-sustaining
R14 166 T11 of_a Enoxaparin,standard prophylactic dose
R140 T181 T112 of_a severe,diseases
R141 T182 T3 of_a LMWH group,standard prophylactic dosage
R144 T7 159 using administered,UFH
R145 T193 T7 into intravenously,administered
R146 T195 T9 of_a 1.5-2.0,aPTT Ratio
R147 T8 T194 of_a 18 UI/kg/hour,infusion rate
R148 T194 T7 at infusion rate,administered
R149 T194 T196 is_a infusion rate,modified
R150 T196 T9 is_a modified,aPTT Ratio
R151 T197 T196 of_a no longer than 12 hours,modified
R152 164 T200 is_a UFH,switched
R153 T200 165 to switched,LMWH
R154 T198 T199 is_a anticoagulant therapy,interrupted
R155 T201 T199 of_a After ICU discharge,interrupted
R156 T201 T200 of_a After ICU discharge,switched
R157 153 T4 of_a patients,standard prophylactic dosage
R158 T188 153 in LMWH + steroid group,patients
R159 158 T5 of_a patients,therapeutic dosages
R160 T191 158 in UFH + steroid group,patients
R161 T183 T11 of_a LMWH group,standard prophylactic dose
R162 T189 T11 of_a LMWH + steroid group,standard prophylactic dose
R163 T125 T11 of_a 4000 UI,standard prophylactic dose
R164 T202 T203 of_a more than 90 kg,weighting
R165 T203 170 of_a weighting,patients
R166 166 T204 of_a Enoxaparin,standard prophylactic dose
R167 T183 T204 of_a LMWH group,standard prophylactic dose
R168 T189 T204 of_a LMWH + steroid group,standard prophylactic dose
R169 T124 T204 of_a 6000 UI,standard prophylactic dose
R170 170 T204 of_a patients,standard prophylactic dose
R171 T14 166 using administered,Enoxaparin
R172 T205 T14 into subcutaneously,administered
R173 T13 T14 of_a up to ICU discharge,administered
R174 T15 T14 of_a once a day,administered
R175 T126 T11 of_a once day,standard prophylactic dose
R176 T127 T204 of_a once day,standard prophylactic dose
R177 T190 T210 of_a LMWH + steroid group,administered
R178 T206 T210 of_a UHF + steroid group,administered
R179 171 T210 of_a Methylprednisolone,administered
R180 T16 171 using intravenously,Methylprednisolone
R182 T131 T210 of_a "0,5 mg/kg",administered
R183 T18 T210 of_a 4 times daily,administered
R184 T19 T210 of_a for 7 days,administered
R185 T17 T210 of_a initial bolus,administered
R186 171 T211 of_a Methylprednisolone,administered
R187 T190 T211 of_a LMWH + steroid group,administered
R188 T206 T211 of_a UHF + steroid group,administered
R189 T132 T211 of_a "0,5 mg/kg",administered
R190 T21 T211 of_a 3 times daily,administered
R191 T22 T211 of_a from day 8 to day 10,administered
R192 171 T212 of_a Methylprednisolone,administered
R193 T190 T212 of_a LMWH + steroid group,administered
R194 T206 T212 of_a UHF + steroid group,administered
R195 T133 T212 of_a "0,5 mg/kg",administered
R196 T24 T212 of_a 2 times daily,administered
R197 T25 T212 of_a at days 11 and 12,administered
R198 171 T213 of_a Methylprednisolone,administered
R199 T190 T213 of_a LMWH + steroid group,administered
R2 150 T3 of_a enoxaparin,standard prophylactic dosage
R200 T206 T213 of_a UHF + steroid group,administered
R201 T134 T213 of_a "0,5 mg/kg",administered
R202 T27 T213 of_a once daily,administered
R203 T28 T213 of_a at days 13 and 14,administered
R204 T214 T113 is_a free,Ventilation
R205 T77 T115 of_a invasive,ventilation
R206 T72 T115 of_a non-invasive,ventilation
R207 T219 T218 of_a invasive mechanical,ventilation
R208 T73 T218 of_a non-invasive,ventilation
R209 T221 T74 of_a non-invasive,ventilation
R210 T220 T82 of_a invasive,ventilation
R211 T34 183 by Candida,infections
R212 T35 183 by Candida,infections
R213 T38 183 by Herpes Virus e Cytomegalovirus,infections
R214 T37 183 by Aspergillus,infections
R215 184 183 by Adenovirus,infections
R216 191 T121 in intraocular,bleeding
R217 T49 T121 in pericardial,bleeding
R218 T51 T121 in intra-articular,bleeding
R219 T52 T121 in intramuscular,bleeding
R220 T46 T121 in intra-spinal,bleeding
R221 T122 191 of_a eye,intraocular
R222 T222 T123 is_a not,conjunctival bleed
R223 T120 T119 of_a retroperitoneal,syndrome
R24 179 T31 of_a steroids,high-dose
R3 154 T4 of_a enoxaparin,standard prophylactic dosage
R34 190 T45 - bleeding,intracranial
R4 155 T4 of_a methylprednisolone,standard prophylactic dosage
R41 195 T55 has_a bleeding,surgical intervention
R42 203 T57 of_a spontaneous hematoma,larger than 25 cm2
R43 208 T60 - any other bleeding,temporary cessation of a study drug
R5 159 T5 of_a UFH,therapeutic dosages
R52 T89 T87 of_a PaO2/FiO2 ratio,lower than 150 mmHg
R54 T68 T88 of_a D-dimer,> 6 times
R55 137 T90 of_a C-reactive Protein,> 6-fold
R6 160 T5 of_a methylprednisolone,therapeutic dosages
R63 T99 T102 of_a surgery,ophthalmic
R64 T99 T101 of_a surgery,spinal
R65 T99 T100 of_a surgery,brain
R69 T30 T31 of_a immune-modulatory drugs,high-dose
R70 T73 T116 - non-invasive,mechanical
R77 T121 194 with bleeding,compartment syndrome
R78 T121 T119 with bleeding,syndrome
R84 231 T141 of_a participants,210
R85 10 9 has_a pneumonia,patients
R86 11 T147 of_a SARS-CoV-2,infection
R87 132 T148 of_a SARS-CoV-2,infection
R88 124 123 abbreviation UFH,unfractionated heparin
R89 127 126 abbreviation LMWH,low molecular weight heparin
R90 T147 9 has_a infection,patients
R91 T64 10 of_a critically ill,pneumonia
R92 T145 10 for ventilated,pneumonia
R93 T148 130 has_a infection,patients
R94 131 130 has_a pneumonia,patients
R95 T149 131 for ventilated,pneumonia
R96 T65 131 of_a critically-ill,pneumonia
R97 T151 T150 of_a adjunctive,therapy
R98 122 T150 using methylprednisolone,therapy
R99 123 T150 using unfractionated heparin,therapy