PubMed:9989503
Annnotations
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 26-29 | protein | denotes | Nmi |
| T2 | 35-40 | protein | denotes | Stat5 |
| T3 | 45-50 | protein | denotes | Stat1 |
| T4 | 54-58 | protein | denotes | IL-2 |
| T5 | 64-72 | protein | denotes | IFNgamma |
| T6 | 125-131 | protein | denotes | Stat5b |
| T7 | 207-210 | protein | denotes | Nmi |
| T8 | 268-273 | protein | denotes | N-Myc |
| T9 | 307-310 | protein | denotes | Nmi |
| T10 | 330-335 | protein | denotes | STATs |
| T11 | 343-348 | protein | denotes | Stat2 |
| T12 | 385-389 | protein | denotes | IL-2 |
| T13 | 394-402 | protein | denotes | IFNgamma |
| T14 | 425-428 | protein | denotes | Nmi |
| T15 | 438-442 | protein | denotes | STAT |
| T16 | 487-496 | protein | denotes | cytokines |
| T17 | 513-516 | protein | denotes | Nmi |
| T18 | 536-569 | protein | denotes | transcriptional activation domain |
| T19 | 580-583 | protein | denotes | Nmi |
| T20 | 612-641 | protein | denotes | CBP/p300 coactivator proteins |
| T21 | 647-652 | protein | denotes | Stat1 |
| T22 | 657-662 | protein | denotes | Stat5 |
| T23 | 682-690 | protein | denotes | CBP/p300 |
| T24 | 788-791 | protein | denotes | Nmi |
| T25 | 807-811 | protein | denotes | STAT |
| T26 | 945-984 | protein | denotes | sequence-specific transcription factors |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-92 | Sentence | denotes | Functional association of Nmi with Stat5 and Stat1 in IL-2- and IFNgamma-mediated signaling. |
| S2 | 93-285 | Sentence | denotes | Using the coiled-coil region of Stat5b as the bait in a yeast two-hybrid screen, we identified the association of Nmi, a protein of unknown function previously reported as an N-Myc interactor. |
| S3 | 286-349 | Sentence | denotes | We further show that Nmi interacts with all STATs except Stat2. |
| S4 | 350-497 | Sentence | denotes | We evaluated two cytokine systems, IL-2 and IFNgamma, and demonstrate that Nmi augments STAT-mediated transcription in response to these cytokines. |
| S5 | 498-746 | Sentence | denotes | Interestingly, Nmi lacks an intrinsic transcriptional activation domain; instead, Nmi enhances the association of CBP/p300 coactivator proteins with Stat1 and Stat5, and together with CBP/p300 can augment IL-2- and IFNgamma-dependent transcription. |
| S6 | 747-985 | Sentence | denotes | Therefore, our data not only reveal that Nmi can potentiate STAT-dependent transcription, but also suggest that it can augment coactivator protein recruitment to at least some members of a group of sequence-specific transcription factors. |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C1 | 26-29 | NP | denotes | Nmi |
| C2 | 35-50 | NP | denotes | Stat5 and Stat1 |
| C3 | 207-210 | NP | denotes | Nmi |
| C4 | 212-284 | NP | denotes | a protein of unknown function previously reported as an N-Myc interactor |
| C5 | 307-310 | NP | denotes | Nmi |
| C6 | 363-383 | NP | denotes | two cytokine systems |
| C7 | 385-402 | NP | denotes | IL-2 and IFNgamma |
| C8 | 425-428 | NP | denotes | Nmi |
| C9 | 481-496 | NP | denotes | these cytokines |
| C10 | 513-516 | NP | denotes | Nmi |
| C11 | 580-583 | NP | denotes | Nmi |
| C12 | 612-641 | NP | denotes | CBP/p300 coactivator proteins |
| C13 | 647-662 | NP | denotes | Stat1 and Stat5 |
| C14 | 682-690 | NP | denotes | CBP/p300 |
| C15 | 788-791 | NP | denotes | Nmi |
| C16 | 859-861 | NP | denotes | it |
| R1 | C3 | C1 | coref-ident | Nmi,Nmi |
| R2 | C4 | C3 | coref-appos | a protein of unknown function previously reported as an N-Myc interactor,Nmi |
| R3 | C5 | C3 | coref-ident | Nmi,Nmi |
| R4 | C7 | C6 | coref-appos | IL-2 and IFNgamma,two cytokine systems |
| R5 | C8 | C5 | coref-ident | Nmi,Nmi |
| R6 | C9 | C6 | coref-ident | these cytokines,two cytokine systems |
| R7 | C10 | C8 | coref-ident | Nmi,Nmi |
| R8 | C11 | C10 | coref-ident | Nmi,Nmi |
| R9 | C13 | C2 | coref-ident | Stat1 and Stat5,Stat5 and Stat1 |
| R10 | C14 | C12 | coref-ident | CBP/p300,CBP/p300 coactivator proteins |
| R11 | C15 | C11 | coref-ident | Nmi,Nmi |
| R12 | C16 | C15 | coref-pron | it,Nmi |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 26-29 | protein_molecule | denotes | Nmi |
| T2 | 35-40 | protein_molecule | denotes | Stat5 |
| T3 | 45-50 | protein_molecule | denotes | Stat1 |
| T4 | 54-58 | protein_molecule | denotes | IL-2 |
| T5 | 64-72 | protein_molecule | denotes | IFNgamma |
| T6 | 125-131 | protein_molecule | denotes | Stat5b |
| T7 | 149-154 | mono_cell | denotes | yeast |
| T8 | 207-210 | protein_molecule | denotes | Nmi |
| T9 | 268-273 | protein_molecule | denotes | N-Myc |
| T10 | 307-310 | protein_molecule | denotes | Nmi |
| T11 | 330-335 | protein_family_or_group | denotes | STATs |
| T12 | 343-348 | protein_molecule | denotes | Stat2 |
| T13 | 385-389 | protein_molecule | denotes | IL-2 |
| T14 | 394-402 | protein_molecule | denotes | IFNgamma |
| T15 | 425-428 | protein_molecule | denotes | Nmi |
| T16 | 438-442 | protein_family_or_group | denotes | STAT |
| T17 | 487-496 | protein_family_or_group | denotes | cytokines |
| T18 | 513-516 | protein_molecule | denotes | Nmi |
| T19 | 536-569 | protein_domain_or_region | denotes | transcriptional activation domain |
| T20 | 580-583 | protein_molecule | denotes | Nmi |
| T21 | 612-641 | protein_family_or_group | denotes | CBP/p300 coactivator proteins |
| T22 | 647-652 | protein_molecule | denotes | Stat1 |
| T23 | 657-662 | protein_molecule | denotes | Stat5 |
| T24 | 682-690 | protein_molecule | denotes | CBP/p300 |
| T25 | 788-791 | protein_molecule | denotes | Nmi |
| T26 | 807-811 | protein_family_or_group | denotes | STAT |
| T27 | 945-984 | protein_family_or_group | denotes | sequence-specific transcription factors |
bionlp-st-gro-2013-development
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 26-29 | Protein | denotes | Nmi |
| T2 | 35-40 | Protein | denotes | Stat5 |
| T3 | 45-50 | Protein | denotes | Stat1 |
| T4 | 54-58 | Protein | denotes | IL-2 |
| T5 | 64-72 | Protein | denotes | IFNgamma |
| T8 | 125-131 | Protein | denotes | Stat5b |
| T9 | 207-210 | Protein | denotes | Nmi |
| T10 | 214-221 | Protein | denotes | protein |
| T11 | 268-273 | Protein | denotes | N-Myc |
| T12 | 307-310 | Protein | denotes | Nmi |
| T14 | 330-335 | Protein | denotes | STATs |
| T15 | 367-375 | Protein | denotes | cytokine |
| T16 | 385-389 | Protein | denotes | IL-2 |
| T17 | 394-402 | Protein | denotes | IFNgamma |
| T18 | 425-428 | Protein | denotes | Nmi |
| T20 | 438-442 | Protein | denotes | STAT |
| T24 | 487-496 | Protein | denotes | cytokines |
| T25 | 513-516 | Protein | denotes | Nmi |
| T29 | 580-583 | Protein | denotes | Nmi |
| T32 | 612-641 | TranscriptionCoactivator | denotes | CBP/p300 coactivator proteins |
| T33 | 647-652 | Protein | denotes | Stat1 |
| T34 | 657-662 | Protein | denotes | Stat5 |
| T35 | 682-690 | Protein | denotes | CBP/p300 |
| T37 | 703-707 | Protein | denotes | IL-2 |
| T38 | 713-721 | Protein | denotes | IFNgamma |
| T40 | 788-791 | Protein | denotes | Nmi |
| T42 | 807-811 | Protein | denotes | STAT |
| T45 | 874-893 | TranscriptionCoactivator | denotes | coactivator protein |
| T47 | 963-984 | TranscriptionFactor | denotes | transcription factors |
| T26 | 536-569 | ProteinDomain | denotes | transcriptional activation domain |
| E1 | 73-81 | RegulatoryProcess | denotes | mediated |
| E2 | 82-91 | SignalingPathway | denotes | signaling |
| E3 | 311-320 | BindingToProtein | denotes | interacts |
| E4 | 429-437 | PositiveRegulation | denotes | augments |
| E5 | 443-451 | RegulatoryProcess | denotes | mediated |
| E6 | 452-465 | Transcription | denotes | transcription |
| E7 | 469-477 | ResponseProcess | denotes | response |
| E10 | 584-592 | PositiveRegulation | denotes | enhances |
| E11 | 597-608 | BindingToProtein | denotes | association |
| E12 | 695-702 | PositiveRegulation | denotes | augment |
| E13 | 732-745 | Transcription | denotes | transcription |
| E14 | 796-806 | PositiveRegulation | denotes | potentiate |
| E15 | 822-835 | Transcription | denotes | transcription |
| E16 | 866-873 | PositiveRegulation | denotes | augment |
| E17 | 894-905 | Transport | denotes | recruitment |
| E18 | 192-203 | BindingToProtein | denotes | association |
| E8 | 73-81 | RegulatoryProcess | denotes | mediated |
| R1 | T4 | E1 | hasAgent | IL-2,mediated |
| R2 | E2 | E1 | hasPatient | signaling,mediated |
| R3 | T14 | E3 | hasPatient | STATs,interacts |
| R4 | T12 | E3 | hasPatient | Nmi,interacts |
| R5 | T18 | E4 | hasAgent | Nmi,augments |
| R6 | E6 | E4 | hasPatient | transcription,augments |
| R7 | T20 | E5 | hasAgent | STAT,mediated |
| R8 | E6 | E5 | hasPatient | transcription,mediated |
| R9 | T24 | E7 | hasAgent | cytokines,response |
| R10 | T29 | E10 | hasAgent | Nmi,enhances |
| R11 | E11 | E10 | hasPatient | association,enhances |
| R12 | T33 | E11 | hasPatient | Stat1,association |
| R13 | T34 | E11 | hasPatient | Stat5,association |
| R14 | T32 | E11 | hasPatient | CBP/p300 coactivator proteins,association |
| R15 | T35 | E12 | hasAgent | CBP/p300,augment |
| R16 | E13 | E12 | hasPatient | transcription,augment |
| R17 | T40 | E14 | hasAgent | Nmi,potentiate |
| R18 | E15 | E14 | hasPatient | transcription,potentiate |
| R19 | T40 | E16 | hasAgent | Nmi,augment |
| R20 | E17 | E16 | hasPatient | recruitment,augment |
| R21 | T45 | E17 | hasPatient | coactivator protein,recruitment |
| R22 | T8 | E18 | hasPatient | Stat5b,association |
| R23 | T9 | E18 | hasPatient | Nmi,association |
| R24 | T5 | E8 | hasAgent | IFNgamma,mediated |
| R25 | E2 | E8 | hasPatient | signaling,mediated |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 612-615 | Disease | denotes | CBP | http://purl.obolibrary.org/obo/MONDO_0010565 |
| T2 | 682-685 | Disease | denotes | CBP | http://purl.obolibrary.org/obo/MONDO_0010565 |