PubMed:28068934 / 415-779
Annnotations
PubTator4TogoVar
{"project":"PubTator4TogoVar","denotations":[{"id":"28068934_0","span":{"begin":76,"end":82},"obj":"ProteinMutation"},{"id":"28068934_1","span":{"begin":88,"end":94},"obj":"ProteinMutation"}],"attributes":[{"id":"28068934_0_ProteinMutation","pred":"proteinmutation","subj":"28068934_0","obj":"rs121913279"},{"id":"28068934_1_ProteinMutation","pred":"proteinmutation","subj":"28068934_1","obj":"rs121913279"}],"text":"We examined five hotspot mutations in the PIK3CA gene (E542K, E545K, E546K, H1047R, and H1047L) in formalin-fixed and paraffin-embedded tissue sections of paired endoscopic biopsy and surgically resected specimens from 181 patients undergoing curative resection for ESCC between 2000 and 2011 using a Luminex technology-based multiplex gene mutation detection kit."}
LitCoin-sentences
{"project":"LitCoin-sentences","denotations":[{"id":"T5","span":{"begin":0,"end":364},"obj":"Sentence"}],"text":"We examined five hotspot mutations in the PIK3CA gene (E542K, E545K, E546K, H1047R, and H1047L) in formalin-fixed and paraffin-embedded tissue sections of paired endoscopic biopsy and surgically resected specimens from 181 patients undergoing curative resection for ESCC between 2000 and 2011 using a Luminex technology-based multiplex gene mutation detection kit."}
LitCoin-entities
{"project":"LitCoin-entities","denotations":[{"id":"12043","span":{"begin":42,"end":48},"obj":"GeneOrGeneProduct"},{"id":"12044","span":{"begin":55,"end":60},"obj":"SequenceVariant"},{"id":"12045","span":{"begin":62,"end":67},"obj":"SequenceVariant"},{"id":"12046","span":{"begin":69,"end":74},"obj":"SequenceVariant"},{"id":"12047","span":{"begin":76,"end":82},"obj":"SequenceVariant"},{"id":"12048","span":{"begin":88,"end":94},"obj":"SequenceVariant"},{"id":"12049","span":{"begin":99,"end":107},"obj":"ChemicalEntity"},{"id":"12050","span":{"begin":118,"end":126},"obj":"ChemicalEntity"},{"id":"12051","span":{"begin":223,"end":231},"obj":"OrganismTaxon"},{"id":"12052","span":{"begin":266,"end":270},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A7","pred":"db_id","subj":"12043","obj":"NCBIGene:5290"},{"id":"A8","pred":"db_id","subj":"12044","obj":"DBSNP:rs121913273"},{"id":"A9","pred":"db_id","subj":"12045","obj":"DBSNP:rs104886003"},{"id":"A10","pred":"db_id","subj":"12046","obj":"p|SUB|E|546|K"},{"id":"A11","pred":"db_id","subj":"12047","obj":"DBSNP:rs121913279"},{"id":"A12","pred":"db_id","subj":"12048","obj":"DBSNP:rs121913279"},{"id":"A13","pred":"db_id","subj":"12049","obj":"MESH:D005557"},{"id":"A14","pred":"db_id","subj":"12050","obj":"MESH:D010232"},{"id":"A15","pred":"db_id","subj":"12051","obj":"NCBITaxon:9606"},{"id":"A16","pred":"db_id","subj":"12052","obj":"MESH:D000077277"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}],"text":"We examined five hotspot mutations in the PIK3CA gene (E542K, E545K, E546K, H1047R, and H1047L) in formalin-fixed and paraffin-embedded tissue sections of paired endoscopic biopsy and surgically resected specimens from 181 patients undergoing curative resection for ESCC between 2000 and 2011 using a Luminex technology-based multiplex gene mutation detection kit."}
LitCoin-SeqVar
{"project":"LitCoin-SeqVar","denotations":[{"id":"T1","span":{"begin":55,"end":60},"obj":"SequenceVariant"},{"id":"T2","span":{"begin":62,"end":67},"obj":"SequenceVariant"},{"id":"T3","span":{"begin":69,"end":74},"obj":"SequenceVariant"},{"id":"T4","span":{"begin":76,"end":82},"obj":"SequenceVariant"},{"id":"T5","span":{"begin":88,"end":94},"obj":"SequenceVariant"}],"text":"We examined five hotspot mutations in the PIK3CA gene (E542K, E545K, E546K, H1047R, and H1047L) in formalin-fixed and paraffin-embedded tissue sections of paired endoscopic biopsy and surgically resected specimens from 181 patients undergoing curative resection for ESCC between 2000 and 2011 using a Luminex technology-based multiplex gene mutation detection kit."}
LitCoin-GeneOrGeneProduct-v0
{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T11","span":{"begin":25,"end":34},"obj":"GeneOrGeneProduct"},{"id":"T12","span":{"begin":42,"end":48},"obj":"GeneOrGeneProduct"},{"id":"T13","span":{"begin":155,"end":161},"obj":"GeneOrGeneProduct"},{"id":"T14","span":{"begin":266,"end":270},"obj":"GeneOrGeneProduct"},{"id":"T15","span":{"begin":320,"end":325},"obj":"GeneOrGeneProduct"},{"id":"T16","span":{"begin":341,"end":349},"obj":"GeneOrGeneProduct"}],"text":"We examined five hotspot mutations in the PIK3CA gene (E542K, E545K, E546K, H1047R, and H1047L) in formalin-fixed and paraffin-embedded tissue sections of paired endoscopic biopsy and surgically resected specimens from 181 patients undergoing curative resection for ESCC between 2000 and 2011 using a Luminex technology-based multiplex gene mutation detection kit."}
LitCoin-GeneOrGeneProduct-v2
{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T6","span":{"begin":42,"end":48},"obj":"GeneOrGeneProduct"},{"id":"T7","span":{"begin":155,"end":161},"obj":"GeneOrGeneProduct"}],"text":"We examined five hotspot mutations in the PIK3CA gene (E542K, E545K, E546K, H1047R, and H1047L) in formalin-fixed and paraffin-embedded tissue sections of paired endoscopic biopsy and surgically resected specimens from 181 patients undergoing curative resection for ESCC between 2000 and 2011 using a Luminex technology-based multiplex gene mutation detection kit."}
LitCoin-Disease-MeSH
{"project":"LitCoin-Disease-MeSH","denotations":[{"id":"T4","span":{"begin":266,"end":270},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A4","pred":"originalLabel","subj":"T4","obj":"D000077277"}],"text":"We examined five hotspot mutations in the PIK3CA gene (E542K, E545K, E546K, H1047R, and H1047L) in formalin-fixed and paraffin-embedded tissue sections of paired endoscopic biopsy and surgically resected specimens from 181 patients undergoing curative resection for ESCC between 2000 and 2011 using a Luminex technology-based multiplex gene mutation detection kit."}
LitCoin-GeneOrGeneProduct-v3
{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T4","span":{"begin":42,"end":48},"obj":"GeneOrGeneProduct"}],"text":"We examined five hotspot mutations in the PIK3CA gene (E542K, E545K, E546K, H1047R, and H1047L) in formalin-fixed and paraffin-embedded tissue sections of paired endoscopic biopsy and surgically resected specimens from 181 patients undergoing curative resection for ESCC between 2000 and 2011 using a Luminex technology-based multiplex gene mutation detection kit."}
LitCoin_Mondo_095
{"project":"LitCoin_Mondo_095","denotations":[{"id":"T4","span":{"begin":266,"end":270},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A4","pred":"mondo_id","subj":"T4","obj":"0005580"}],"text":"We examined five hotspot mutations in the PIK3CA gene (E542K, E545K, E546K, H1047R, and H1047L) in formalin-fixed and paraffin-embedded tissue sections of paired endoscopic biopsy and surgically resected specimens from 181 patients undergoing curative resection for ESCC between 2000 and 2011 using a Luminex technology-based multiplex gene mutation detection kit."}
LitCoin-MeSH-Disease-2
{"project":"LitCoin-MeSH-Disease-2","denotations":[{"id":"T4","span":{"begin":266,"end":270},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A4","pred":"ID:","subj":"T4","obj":"D000077277"}],"text":"We examined five hotspot mutations in the PIK3CA gene (E542K, E545K, E546K, H1047R, and H1047L) in formalin-fixed and paraffin-embedded tissue sections of paired endoscopic biopsy and surgically resected specimens from 181 patients undergoing curative resection for ESCC between 2000 and 2011 using a Luminex technology-based multiplex gene mutation detection kit."}
LitCoin-NCBITaxon-2
{"project":"LitCoin-NCBITaxon-2","denotations":[{"id":"T1","span":{"begin":223,"end":231},"obj":"OrganismTaxon"}],"text":"We examined five hotspot mutations in the PIK3CA gene (E542K, E545K, E546K, H1047R, and H1047L) in formalin-fixed and paraffin-embedded tissue sections of paired endoscopic biopsy and surgically resected specimens from 181 patients undergoing curative resection for ESCC between 2000 and 2011 using a Luminex technology-based multiplex gene mutation detection kit."}
LitCoin-MONDO_bioort2019
{"project":"LitCoin-MONDO_bioort2019","denotations":[{"id":"T4","span":{"begin":266,"end":270},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A4","pred":"#label","subj":"T4","obj":"D000077277"}],"text":"We examined five hotspot mutations in the PIK3CA gene (E542K, E545K, E546K, H1047R, and H1047L) in formalin-fixed and paraffin-embedded tissue sections of paired endoscopic biopsy and surgically resected specimens from 181 patients undergoing curative resection for ESCC between 2000 and 2011 using a Luminex technology-based multiplex gene mutation detection kit."}
LitCoin-Chemical-MeSH-CHEBI
{"project":"LitCoin-Chemical-MeSH-CHEBI","denotations":[{"id":"T1","span":{"begin":99,"end":107},"obj":"ChemicalEntity"},{"id":"T2","span":{"begin":118,"end":126},"obj":"ChemicalEntity"}],"attributes":[{"id":"A1","pred":"ID:","subj":"T1","obj":"D005557"},{"id":"A2","pred":"ID:","subj":"T2","obj":"D010232"},{"id":"A3","pred":"ID:","subj":"T2","obj":"ChemicalEntity"}],"text":"We examined five hotspot mutations in the PIK3CA gene (E542K, E545K, E546K, H1047R, and H1047L) in formalin-fixed and paraffin-embedded tissue sections of paired endoscopic biopsy and surgically resected specimens from 181 patients undergoing curative resection for ESCC between 2000 and 2011 using a Luminex technology-based multiplex gene mutation detection kit."}
LitCoin-training-merged
{"project":"LitCoin-training-merged","denotations":[{"id":"T2","span":{"begin":118,"end":126},"obj":"ChemicalEntity"},{"id":"T1","span":{"begin":99,"end":107},"obj":"ChemicalEntity"},{"id":"T4","span":{"begin":42,"end":48},"obj":"GeneOrGeneProduct"},{"id":"T76861","span":{"begin":266,"end":270},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T58424","span":{"begin":223,"end":231},"obj":"OrganismTaxon"},{"id":"T74027","span":{"begin":88,"end":94},"obj":"SequenceVariant"},{"id":"T42809","span":{"begin":76,"end":82},"obj":"SequenceVariant"},{"id":"T3154","span":{"begin":69,"end":74},"obj":"SequenceVariant"},{"id":"T72399","span":{"begin":62,"end":67},"obj":"SequenceVariant"},{"id":"T23816","span":{"begin":55,"end":60},"obj":"SequenceVariant"}],"attributes":[{"id":"A3","pred":"ID:","subj":"T2","obj":"ChemicalEntity"},{"id":"A2","pred":"ID:","subj":"T2","obj":"D010232"},{"id":"A1","pred":"ID:","subj":"T1","obj":"D005557"},{"id":"A4","pred":"#label","subj":"T76861","obj":"D000077277"}],"text":"We examined five hotspot mutations in the PIK3CA gene (E542K, E545K, E546K, H1047R, and H1047L) in formalin-fixed and paraffin-embedded tissue sections of paired endoscopic biopsy and surgically resected specimens from 181 patients undergoing curative resection for ESCC between 2000 and 2011 using a Luminex technology-based multiplex gene mutation detection kit."}