PubMed:25372662 / 850-1590
Annnotations
Inflammaging
{"project":"Inflammaging","denotations":[{"id":"T7","span":{"begin":0,"end":740},"obj":"Sentence"},{"id":"T7","span":{"begin":0,"end":740},"obj":"Sentence"}],"text":"We validated three SNPs (rs78142040, rs9605146 and rs3848719) in additional ARDS patients to substantiate their associations with susceptibility, severity and outcome of ARDS. rs78142040 (C\u003eT) occurs within a histone mark (intron 6) of the Arylsulfatase D gene. rs9605146 (G\u003eA) causes a deleterious coding change (proline to leucine) in the XK, Kell blood group complex subunit-related family, member 3 gene. rs3848719 (G\u003eA) is a synonymous SNP in the Zinc-Finger/Leucine-Zipper Co-Transducer NIF1 gene. rs78142040, rs9605146, and rs3848719 are associated significantly with susceptibility to ARDS. rs3848719 is associated with APACHE II score quartile. rs78142040 is associated with 60-day mortality in the overall ARDS patient population."}
DisGeNET5_variant_disease
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1274282"},{"id":"51#60#geners3848719716#720#diseaseC0035222","pred":"associated_with","subj":"25372662-6#51#60#geners3848719","obj":"25372662-6#716#720#diseaseC0035222"}],"text":"We validated three SNPs (rs78142040, rs9605146 and rs3848719) in additional ARDS patients to substantiate their associations with susceptibility, severity and outcome of ARDS. rs78142040 (C\u003eT) occurs within a histone mark (intron 6) of the Arylsulfatase D gene. rs9605146 (G\u003eA) causes a deleterious coding change (proline to leucine) in the XK, Kell blood group complex subunit-related family, member 3 gene. rs3848719 (G\u003eA) is a synonymous SNP in the Zinc-Finger/Leucine-Zipper Co-Transducer NIF1 gene. rs78142040, rs9605146, and rs3848719 are associated significantly with susceptibility to ARDS. rs3848719 is associated with APACHE II score quartile. rs78142040 is associated with 60-day mortality in the overall ARDS patient population."}
DisGeNET5_gene_disease
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validated three SNPs (rs78142040, rs9605146 and rs3848719) in additional ARDS patients to substantiate their associations with susceptibility, severity and outcome of ARDS. rs78142040 (C\u003eT) occurs within a histone mark (intron 6) of the Arylsulfatase D gene. rs9605146 (G\u003eA) causes a deleterious coding change (proline to leucine) in the XK, Kell blood group complex subunit-related family, member 3 gene. rs3848719 (G\u003eA) is a synonymous SNP in the Zinc-Finger/Leucine-Zipper Co-Transducer NIF1 gene. rs78142040, rs9605146, and rs3848719 are associated significantly with susceptibility to ARDS. rs3848719 is associated with APACHE II score quartile. rs78142040 is associated with 60-day mortality in the overall ARDS patient population."}