PubMed:25286407 / 154-594
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/25286407","sourcedb":"PubMed","sourceid":"25286407","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/25286407","text":"Analgesic discography (discoblock) can be used to diagnose or treat discogenic low back pain by injecting a small amount of local anesthetics. However, recent in vitro studies have revealed cytotoxic effects of local anesthetics on intervertebral disc (IVD) cells. Here we aimed to investigate the deteriorative effects of lidocaine and bupivacaine on rabbit IVDs using an organotypic culture model and an in vivo long-term follow-up model.","tracks":[{"project":"PubMed_Structured_Abstracts","denotations":[{"id":"T1","span":{"begin":0,"end":440},"obj":"BACKGROUND"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubMed_Structured_Abstracts"}]},{"project":"Goldhamster2_Cellosaurus","denotations":[{"id":"T1","span":{"begin":106,"end":107},"obj":"CVCL_6479|Finite_cell_line|Mus musculus"},{"id":"T2","span":{"begin":270,"end":272},"obj":"CVCL_5M23|Cancer_cell_line|Mesocricetus auratus"},{"id":"T3","span":{"begin":370,"end":372},"obj":"CVCL_8754|Cancer_cell_line|Homo sapiens"},{"id":"T4","span":{"begin":370,"end":372},"obj":"CVCL_H241|Cancer_cell_line|Homo sapiens"},{"id":"T5","span":{"begin":403,"end":405},"obj":"CVCL_8754|Cancer_cell_line|Homo sapiens"},{"id":"T6","span":{"begin":403,"end":405},"obj":"CVCL_H241|Cancer_cell_line|Homo sapiens"}],"attributes":[{"subj":"T1","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T2","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T3","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T4","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T5","pred":"source","obj":"Goldhamster2_Cellosaurus"},{"subj":"T6","pred":"source","obj":"Goldhamster2_Cellosaurus"}]},{"project":"GoldHamster","denotations":[{"id":"T11","span":{"begin":0,"end":9},"obj":"CHEBI:35480"},{"id":"T12","span":{"begin":79,"end":92},"obj":"D017116"},{"id":"T13","span":{"begin":79,"end":92},"obj":"D017116"},{"id":"T16","span":{"begin":88,"end":92},"obj":"PR:Q9W0Y6"},{"id":"T17","span":{"begin":124,"end":141},"obj":"CHEBI:36333"},{"id":"T18","span":{"begin":124,"end":141},"obj":"D000779"},{"id":"T19","span":{"begin":124,"end":141},"obj":"D000779"},{"id":"T23","span":{"begin":211,"end":228},"obj":"CHEBI:36333"},{"id":"T24","span":{"begin":211,"end":228},"obj":"D000779"},{"id":"T25","span":{"begin":211,"end":228},"obj":"D000779"},{"id":"T31","span":{"begin":232,"end":251},"obj":"UBERON:0001066"},{"id":"T29","span":{"begin":232,"end":251},"obj":"C535531"},{"id":"T30","span":{"begin":232,"end":251},"obj":"C535531"},{"id":"T32","span":{"begin":253,"end":256},"obj":"Q9FS87"},{"id":"T33","span":{"begin":253,"end":256},"obj":"Q9SWG0"},{"id":"T34","span":{"begin":253,"end":256},"obj":"P12007"},{"id":"T35","span":{"begin":253,"end":256},"obj":"P26440"},{"id":"T36","span":{"begin":253,"end":256},"obj":"Q3SZI8"},{"id":"T37","span":{"begin":253,"end":256},"obj":"PR:P12007"},{"id":"T38","span":{"begin":253,"end":256},"obj":"P34275"},{"id":"T39","span":{"begin":253,"end":256},"obj":"Q9JHI5"},{"id":"T40","span":{"begin":253,"end":256},"obj":"PR:Q9SWG0"},{"id":"T41","span":{"begin":253,"end":256},"obj":"Q75IM9"},{"id":"T42","span":{"begin":253,"end":256},"obj":"PR:P26440"},{"id":"T43","span":{"begin":253,"end":256},"obj":"Q5RBD5"},{"id":"T44","span":{"begin":253,"end":256},"obj":"PR:000009166"},{"id":"T45","span":{"begin":253,"end":256},"obj":"PR:Q9JHI5"},{"id":"T46","span":{"begin":323,"end":332},"obj":"6387"},{"id":"T47","span":{"begin":323,"end":332},"obj":"D008012"},{"id":"T48","span":{"begin":323,"end":332},"obj":"CHEBI:6456"},{"id":"T49","span":{"begin":323,"end":332},"obj":"D008012"},{"id":"T51","span":{"begin":337,"end":348},"obj":"1815"},{"id":"T50","span":{"begin":337,"end":348},"obj":"D002045"},{"id":"T52","span":{"begin":337,"end":348},"obj":"CHEBI:3215"},{"id":"T53","span":{"begin":337,"end":348},"obj":"CHEBI:60790"},{"id":"T54","span":{"begin":337,"end":348},"obj":"CHEBI:6149"},{"id":"T55","span":{"begin":337,"end":348},"obj":"D002045"},{"id":"T57","span":{"begin":352,"end":358},"obj":"813859"},{"id":"T56","span":{"begin":352,"end":358},"obj":"D011817"},{"id":"T58","span":{"begin":352,"end":358},"obj":"9986"},{"id":"T59","span":{"begin":419,"end":423},"obj":"original_id"}],"attributes":[{"subj":"T11","pred":"source","obj":"GoldHamster"},{"subj":"T12","pred":"source","obj":"GoldHamster"},{"subj":"T13","pred":"source","obj":"GoldHamster"},{"subj":"T16","pred":"source","obj":"GoldHamster"},{"subj":"T17","pred":"source","obj":"GoldHamster"},{"subj":"T18","pred":"source","obj":"GoldHamster"},{"subj":"T19","pred":"source","obj":"GoldHamster"},{"subj":"T23","pred":"source","obj":"GoldHamster"},{"subj":"T24","pred":"source","obj":"GoldHamster"},{"subj":"T25","pred":"source","obj":"GoldHamster"},{"subj":"T31","pred":"source","obj":"GoldHamster"},{"subj":"T29","pred":"source","obj":"GoldHamster"},{"subj":"T30","pred":"source","obj":"GoldHamster"},{"subj":"T32","pred":"source","obj":"GoldHamster"},{"subj":"T33","pred":"source","obj":"GoldHamster"},{"subj":"T34","pred":"source","obj":"GoldHamster"},{"subj":"T35","pred":"source","obj":"GoldHamster"},{"subj":"T36","pred":"source","obj":"GoldHamster"},{"subj":"T37","pred":"source","obj":"GoldHamster"},{"subj":"T38","pred":"source","obj":"GoldHamster"},{"subj":"T39","pred":"source","obj":"GoldHamster"},{"subj":"T40","pred":"source","obj":"GoldHamster"},{"subj":"T41","pred":"source","obj":"GoldHamster"},{"subj":"T42","pred":"source","obj":"GoldHamster"},{"subj":"T43","pred":"source","obj":"GoldHamster"},{"subj":"T44","pred":"source","obj":"GoldHamster"},{"subj":"T45","pred":"source","obj":"GoldHamster"},{"subj":"T46","pred":"source","obj":"GoldHamster"},{"subj":"T47","pred":"source","obj":"GoldHamster"},{"subj":"T48","pred":"source","obj":"GoldHamster"},{"subj":"T49","pred":"source","obj":"GoldHamster"},{"subj":"T51","pred":"source","obj":"GoldHamster"},{"subj":"T50","pred":"source","obj":"GoldHamster"},{"subj":"T52","pred":"source","obj":"GoldHamster"},{"subj":"T53","pred":"source","obj":"GoldHamster"},{"subj":"T54","pred":"source","obj":"GoldHamster"},{"subj":"T55","pred":"source","obj":"GoldHamster"},{"subj":"T57","pred":"source","obj":"GoldHamster"},{"subj":"T56","pred":"source","obj":"GoldHamster"},{"subj":"T58","pred":"source","obj":"GoldHamster"},{"subj":"T59","pred":"source","obj":"GoldHamster"}]},{"project":"PubmedHPO","denotations":[{"id":"T1","span":{"begin":79,"end":92},"obj":"HP_0003419"},{"id":"T2","span":{"begin":83,"end":92},"obj":"HP_0003418"},{"id":"T3","span":{"begin":88,"end":92},"obj":"HP_0012531"}],"attributes":[{"subj":"T1","pred":"source","obj":"PubmedHPO"},{"subj":"T2","pred":"source","obj":"PubmedHPO"},{"subj":"T3","pred":"source","obj":"PubmedHPO"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"PubMed_Structured_Abstracts","color":"#e593ec","default":true},{"id":"Goldhamster2_Cellosaurus","color":"#93eccb"},{"id":"GoldHamster","color":"#ecb193"},{"id":"PubmedHPO","color":"#9793ec"}]}]}}