PubMed:24581344 / 111-729 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/24581344","sourcedb":"PubMed","sourceid":"24581344","source_url":"https://www.ncbi.nlm.nih.gov/pubmed/24581344","text":"Extracellular matrix (ECM) disarray is found in calcific aortic valvular disease (CAVD), yet much remains to be learned about the role of individual ECM components in valvular interstitial cell (VIC) function and dysfunction. Previous clinical analyses have shown that calcification is associated with decreased collagen content, while previous in vitro work has suggested that the presence of collagen attenuates the responsiveness of VICs to pro-calcific stimuli. 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