PubMed:23035012 / 887-1215 JSONTXT

{"project":"CL-cell","denotations":[{"id":"T18","span":{"begin":47,"end":56},"obj":"Cell"},{"id":"T20","span":{"begin":145,"end":154},"obj":"Cell"},{"id":"T22","span":{"begin":155,"end":166},"obj":"Cell"},{"id":"T24","span":{"begin":171,"end":183},"obj":"Cell"}],"attributes":[{"id":"A18","pred":"cl_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/CL:0000576"},{"id":"A19","pred":"cl_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/CL:0001054"},{"id":"A20","pred":"cl_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CL:0000576"},{"id":"A21","pred":"cl_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CL:0001054"},{"id":"A22","pred":"cl_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/CL:0000235"},{"id":"A23","pred":"cl_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/CL:0000394"},{"id":"A24","pred":"cl_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/CL:0001064"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"Glycosmos6-MAT","denotations":[{"id":"T1","span":{"begin":89,"end":93},"obj":"http://purl.obolibrary.org/obo/MAT_0000135"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"sentences","denotations":[{"id":"TextSentencer_T6","span":{"begin":0,"end":328},"obj":"Sentence"},{"id":"T6","span":{"begin":0,"end":328},"obj":"Sentence"},{"id":"T6","span":{"begin":0,"end":328},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"GlycoBiology-FMA","denotations":[{"id":"_T27","span":{"begin":47,"end":56},"obj":"FMAID:167164"},{"id":"_T28","span":{"begin":47,"end":56},"obj":"FMAID:62864"},{"id":"_T29","span":{"begin":67,"end":72},"obj":"FMAID:169002"},{"id":"_T30","span":{"begin":67,"end":72},"obj":"FMAID:68646"},{"id":"_T31","span":{"begin":89,"end":93},"obj":"FMAID:7195"},{"id":"_T32","span":{"begin":89,"end":93},"obj":"FMAID:93670"},{"id":"_T33","span":{"begin":89,"end":93},"obj":"FMAID:169341"},{"id":"_T34","span":{"begin":105,"end":110},"obj":"FMAID:68646"},{"id":"_T35","span":{"begin":105,"end":110},"obj":"FMAID:169002"},{"id":"_T36","span":{"begin":145,"end":154},"obj":"FMAID:167164"},{"id":"_T37","span":{"begin":145,"end":154},"obj":"FMAID:62864"},{"id":"_T38","span":{"begin":155,"end":166},"obj":"FMAID:63261"},{"id":"_T39","span":{"begin":155,"end":166},"obj":"FMAID:167685"},{"id":"_T40","span":{"begin":178,"end":183},"obj":"FMAID:169002"},{"id":"_T41","span":{"begin":178,"end":183},"obj":"FMAID:68646"},{"id":"_T42","span":{"begin":263,"end":268},"obj":"FMAID:68646"},{"id":"_T43","span":{"begin":263,"end":268},"obj":"FMAID:169002"},{"id":"_T44","span":{"begin":322,"end":327},"obj":"FMAID:169002"},{"id":"_T45","span":{"begin":322,"end":327},"obj":"FMAID:68646"}],"namespaces":[{"prefix":"FMAID","uri":"http://purl.org/sig/ont/fma/fma"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"uniprot-human","denotations":[{"id":"T5","span":{"begin":236,"end":245},"obj":"http://www.uniprot.org/uniprot/Q6ZMC9"},{"id":"T16","span":{"begin":34,"end":37},"obj":"http://www.uniprot.org/uniprot/P10070"},{"id":"T17","span":{"begin":257,"end":260},"obj":"http://www.uniprot.org/uniprot/P10070"},{"id":"T19","span":{"begin":34,"end":37},"obj":"http://www.uniprot.org/uniprot/P07911"},{"id":"T20","span":{"begin":257,"end":260},"obj":"http://www.uniprot.org/uniprot/P07911"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"uniprot-mouse","denotations":[{"id":"T2","span":{"begin":34,"end":37},"obj":"http://www.uniprot.org/uniprot/Q91X17"},{"id":"T3","span":{"begin":257,"end":260},"obj":"http://www.uniprot.org/uniprot/Q91X17"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"GlycoBiology-NCBITAXON","denotations":[{"id":"T6","span":{"begin":14,"end":16},"obj":"http://purl.bioontology.org/ontology/NCBITAXON/13893"},{"id":"T7","span":{"begin":67,"end":72},"obj":"http://purl.bioontology.org/ontology/STY/T025"},{"id":"T8","span":{"begin":94,"end":103},"obj":"http://purl.bioontology.org/ontology/NCBITAXON/166034"},{"id":"T9","span":{"begin":105,"end":110},"obj":"http://purl.bioontology.org/ontology/STY/T025"},{"id":"T10","span":{"begin":171,"end":177},"obj":"http://purl.bioontology.org/ontology/NCBITAXON/6754"},{"id":"T11","span":{"begin":178,"end":183},"obj":"http://purl.bioontology.org/ontology/STY/T025"},{"id":"T12","span":{"begin":263,"end":268},"obj":"http://purl.bioontology.org/ontology/STY/T025"},{"id":"T13","span":{"begin":322,"end":327},"obj":"http://purl.bioontology.org/ontology/STY/T025"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"GO-BP","denotations":[{"id":"T7","span":{"begin":276,"end":284},"obj":"http://purl.obolibrary.org/obo/GO_0007349"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"GO-CC","denotations":[{"id":"T4","span":{"begin":67,"end":72},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T5","span":{"begin":105,"end":110},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T6","span":{"begin":178,"end":183},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T7","span":{"begin":263,"end":268},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T8","span":{"begin":322,"end":327},"obj":"http://purl.obolibrary.org/obo/GO_0005623"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"UBERON-AE","denotations":[{"id":"T2","span":{"begin":89,"end":93},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"PubmedHPO","denotations":[{"id":"T5","span":{"begin":57,"end":65},"obj":"HP_0001909"},{"id":"T6","span":{"begin":171,"end":177},"obj":"HP_0002664"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"GlycoBiology-MAT","denotations":[{"id":"T1","span":{"begin":89,"end":93},"obj":"http://purl.obolibrary.org/obo/MAT_0000135"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"performance-test","denotations":[{"id":"PD-UBERON-AE-B_T2","span":{"begin":89,"end":93},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"mondo_disease","denotations":[{"id":"T6","span":{"begin":47,"end":65},"obj":"Disease"},{"id":"T8","span":{"begin":89,"end":103},"obj":"Disease"},{"id":"T9","span":{"begin":171,"end":177},"obj":"Disease"}],"attributes":[{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0004600"},{"id":"A7","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0007896"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0005138"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0004992"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"Anatomy-MAT","denotations":[{"id":"T1","span":{"begin":89,"end":93},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"mat_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MAT_0000135"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"GlyCosmos15-HP","denotations":[{"id":"T6","span":{"begin":57,"end":65},"obj":"Phenotype"},{"id":"T7","span":{"begin":94,"end":103},"obj":"Phenotype"},{"id":"T8","span":{"begin":171,"end":177},"obj":"Phenotype"}],"attributes":[{"id":"A6","pred":"hp_id","subj":"T6","obj":"HP:0001909"},{"id":"A7","pred":"hp_id","subj":"T7","obj":"HP:0030731"},{"id":"A8","pred":"hp_id","subj":"T8","obj":"HP:0002664"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"GlyCosmos15-MONDO","denotations":[{"id":"T6","span":{"begin":47,"end":65},"obj":"Disease"},{"id":"T8","span":{"begin":89,"end":103},"obj":"Disease"},{"id":"T9","span":{"begin":171,"end":177},"obj":"Disease"}],"attributes":[{"id":"A6","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0004600"},{"id":"A7","pred":"mondo_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/MONDO_0007896"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/MONDO_0005138"},{"id":"A9","pred":"mondo_id","subj":"T9","obj":"http://purl.obolibrary.org/obo/MONDO_0004992"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"GlyCosmos15-NCBITAXON","denotations":[{"id":"T2","span":{"begin":41,"end":46},"obj":"OrganismTaxon"},{"id":"T3","span":{"begin":83,"end":88},"obj":"OrganismTaxon"}],"attributes":[{"id":"A2","pred":"db_id","subj":"T2","obj":"9606"},{"id":"A3","pred":"db_id","subj":"T3","obj":"9606"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"GlyCosmos15-CL","denotations":[{"id":"T18","span":{"begin":47,"end":56},"obj":"Cell"},{"id":"T20","span":{"begin":145,"end":154},"obj":"Cell"},{"id":"T22","span":{"begin":155,"end":166},"obj":"Cell"},{"id":"T24","span":{"begin":171,"end":183},"obj":"Cell"}],"attributes":[{"id":"A18","pred":"cl_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/CL:0000576"},{"id":"A19","pred":"cl_id","subj":"T18","obj":"http://purl.obolibrary.org/obo/CL:0001054"},{"id":"A20","pred":"cl_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CL:0000576"},{"id":"A21","pred":"cl_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/CL:0001054"},{"id":"A22","pred":"cl_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/CL:0000235"},{"id":"A23","pred":"cl_id","subj":"T22","obj":"http://purl.obolibrary.org/obo/CL:0000394"},{"id":"A24","pred":"cl_id","subj":"T24","obj":"http://purl.obolibrary.org/obo/CL:0001064"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"GlyCosmos15-UBERON","denotations":[{"id":"T11","span":{"begin":89,"end":93},"obj":"Body_part"},{"id":"T12","span":{"begin":145,"end":154},"obj":"Body_part"},{"id":"T14","span":{"begin":155,"end":166},"obj":"Body_part"}],"attributes":[{"id":"A11","pred":"uberon_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A12","pred":"uberon_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"A13","pred":"uberon_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CL_0001054"},{"id":"A14","pred":"uberon_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CL_0000235"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"GlyCosmos15-MAT","denotations":[{"id":"T1","span":{"begin":89,"end":93},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"mat_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/MAT_0000135"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"sentences","denotations":[{"id":"TextSentencer_T6","span":{"begin":0,"end":328},"obj":"Sentence"},{"id":"T6","span":{"begin":0,"end":328},"obj":"Sentence"},{"id":"T6","span":{"begin":0,"end":328},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"GlyCosmos15-Sentences","blocks":[{"id":"T6","span":{"begin":0,"end":328},"obj":"Sentence"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"NCBITAXON","denotations":[{"id":"T2","span":{"begin":41,"end":46},"obj":"OrganismTaxon"},{"id":"T3","span":{"begin":83,"end":88},"obj":"OrganismTaxon"}],"attributes":[{"id":"A2","pred":"db_id","subj":"T2","obj":"9606"},{"id":"A3","pred":"db_id","subj":"T3","obj":"9606"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"Anatomy-UBERON","denotations":[{"id":"T11","span":{"begin":89,"end":93},"obj":"Body_part"},{"id":"T12","span":{"begin":145,"end":154},"obj":"Body_part"},{"id":"T14","span":{"begin":155,"end":166},"obj":"Body_part"}],"attributes":[{"id":"A11","pred":"uberon_id","subj":"T11","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A12","pred":"uberon_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CL_0000576"},{"id":"A13","pred":"uberon_id","subj":"T12","obj":"http://purl.obolibrary.org/obo/CL_0001054"},{"id":"A14","pred":"uberon_id","subj":"T14","obj":"http://purl.obolibrary.org/obo/CL_0000235"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}

{"project":"HP-phenotype","denotations":[{"id":"T6","span":{"begin":57,"end":65},"obj":"Phenotype"},{"id":"T7","span":{"begin":94,"end":103},"obj":"Phenotype"},{"id":"T8","span":{"begin":171,"end":177},"obj":"Phenotype"}],"attributes":[{"id":"A6","pred":"hp_id","subj":"T6","obj":"HP:0001909"},{"id":"A7","pred":"hp_id","subj":"T7","obj":"HP:0030731"},{"id":"A8","pred":"hp_id","subj":"T8","obj":"HP:0002664"}],"namespaces":[{"prefix":"HP","uri":"http://purl.obolibrary.org/obo/HP_"}],"text":"We designed a co-culture model of THP-1 (human monocytic leukemia) cells and H157 (human lung carcinoma) cells mimicking the interaction between monocytes/macrophages and cancer cells that recapitulated the enhanced TGF-β production in Siglec-15 expressing THP-1 cells by the cellular interaction with sTn expressing H157 cells."}