PubMed:22711886 / 1748-2102 JSONTXT

{"project":"LitCoin-entities-OrganismTaxon-PD","denotations":[{"id":"T9","span":{"begin":148,"end":152},"obj":"OrganismTaxon"}],"attributes":[{"id":"A9","pred":"db_id","subj":"T9","obj":"NCBItxid:10095"},{"id":"A10","pred":"db_id","subj":"T9","obj":"NCBItxid:10088"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}

{"project":"LitCoin-sentences","denotations":[{"id":"T18","span":{"begin":0,"end":354},"obj":"Sentence"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}

{"project":"LitCoin-entities","denotations":[{"id":"9013","span":{"begin":37,"end":42},"obj":"GeneOrGeneProduct"},{"id":"9014","span":{"begin":70,"end":75},"obj":"GeneOrGeneProduct"},{"id":"9015","span":{"begin":89,"end":117},"obj":"DiseaseOrPhenotypicFeature"},{"id":"9016","span":{"begin":118,"end":144},"obj":"DiseaseOrPhenotypicFeature"},{"id":"9017","span":{"begin":148,"end":152},"obj":"OrganismTaxon"},{"id":"9018","span":{"begin":235,"end":266},"obj":"GeneOrGeneProduct"},{"id":"9019","span":{"begin":316,"end":340},"obj":"GeneOrGeneProduct"}],"attributes":[{"id":"A40","pred":"db_id","subj":"9013","obj":"NCBIGene:22030"},{"id":"A41","pred":"db_id","subj":"9014","obj":"NCBIGene:596"},{"id":"A42","pred":"db_id","subj":"9015","obj":"MESH:D015451"},{"id":"A43","pred":"db_id","subj":"9016","obj":"MESH:D015451"},{"id":"A44","pred":"db_id","subj":"9017","obj":"NCBITaxon:10090"},{"id":"A45","pred":"db_id","subj":"9018","obj":"NCBIGene:11798"},{"id":"A46","pred":"db_id","subj":"9019","obj":"NCBIGene:24099"}],"namespaces":[{"prefix":"_base","uri":"https://w3id.org/biolink/vocab/"},{"prefix":"MESH","uri":"http://id.nlm.nih.gov/mesh/"},{"prefix":"NCBITaxon","uri":"https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?id="},{"prefix":"NCBIGene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"OMIM","uri":"https://www.omim.org/entry/"},{"prefix":"DBSNP","uri":"https://www.ncbi.nlm.nih.gov/snp/"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}

{"project":"LitCoin_Mondo","denotations":[{"id":"T6","span":{"begin":89,"end":144},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T7","span":{"begin":109,"end":117},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T8","span":{"begin":136,"end":144},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A6","pred":"mondo_id","subj":"T6","obj":"0003864"},{"id":"A7","pred":"mondo_id","subj":"T7","obj":"0005059"},{"id":"A8","pred":"mondo_id","subj":"T8","obj":"0005062"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}

{"project":"LitCoin-GeneOrGeneProduct-v0","denotations":[{"id":"T70","span":{"begin":37,"end":42},"obj":"GeneOrGeneProduct"},{"id":"T71","span":{"begin":70,"end":75},"obj":"GeneOrGeneProduct"},{"id":"T72","span":{"begin":97,"end":108},"obj":"GeneOrGeneProduct"},{"id":"T73","span":{"begin":118,"end":123},"obj":"GeneOrGeneProduct"},{"id":"T74","span":{"begin":124,"end":135},"obj":"GeneOrGeneProduct"},{"id":"T75","span":{"begin":148,"end":152},"obj":"GeneOrGeneProduct"},{"id":"T76","span":{"begin":189,"end":197},"obj":"GeneOrGeneProduct"},{"id":"T77","span":{"begin":205,"end":209},"obj":"GeneOrGeneProduct"},{"id":"T78","span":{"begin":235,"end":266},"obj":"GeneOrGeneProduct"},{"id":"T79","span":{"begin":295,"end":300},"obj":"GeneOrGeneProduct"},{"id":"T80","span":{"begin":316,"end":340},"obj":"GeneOrGeneProduct"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}

{"project":"LitCoin-GeneOrGeneProduct-v2","denotations":[{"id":"T40","span":{"begin":37,"end":42},"obj":"GeneOrGeneProduct"},{"id":"T41","span":{"begin":70,"end":75},"obj":"GeneOrGeneProduct"},{"id":"T42","span":{"begin":118,"end":123},"obj":"GeneOrGeneProduct"},{"id":"T43","span":{"begin":205,"end":209},"obj":"GeneOrGeneProduct"},{"id":"T44","span":{"begin":235,"end":266},"obj":"GeneOrGeneProduct"},{"id":"T45","span":{"begin":316,"end":340},"obj":"GeneOrGeneProduct"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}

{"project":"LitCoin-Disease-MeSH","denotations":[{"id":"T5","span":{"begin":89,"end":117},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":118,"end":144},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A5","pred":"originalLabel","subj":"T5","obj":"D015451"},{"id":"A6","pred":"originalLabel","subj":"T6","obj":"D015451"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}

{"project":"LitCoin-GeneOrGeneProduct-v3","denotations":[{"id":"T27","span":{"begin":37,"end":42},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":70,"end":75},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":235,"end":266},"obj":"GeneOrGeneProduct"},{"id":"T30","span":{"begin":316,"end":340},"obj":"GeneOrGeneProduct"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}

{"project":"LitCoin_Mondo_095","denotations":[{"id":"T5","span":{"begin":89,"end":144},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A5","pred":"mondo_id","subj":"T5","obj":"0003864"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}

{"project":"LitCoin-MeSH-Disease-2","denotations":[{"id":"T5","span":{"begin":89,"end":117},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":118,"end":144},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A5","pred":"ID:","subj":"T5","obj":"D015451"},{"id":"A6","pred":"ID:","subj":"T6","obj":"D015451"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}

{"project":"LitCoin-MONDO_bioort2019","denotations":[{"id":"T5","span":{"begin":89,"end":117},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T6","span":{"begin":118,"end":144},"obj":"DiseaseOrPhenotypicFeature"}],"attributes":[{"id":"A5","pred":"#label","subj":"T5","obj":"D015451"},{"id":"A6","pred":"#label","subj":"T6","obj":"D015451"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}

{"project":"LitCoin-NCBITaxon-2","denotations":[{"id":"T5","span":{"begin":148,"end":152},"obj":"OrganismTaxon"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}

{"project":"LitCoin-training-merged","denotations":[{"id":"T30","span":{"begin":316,"end":340},"obj":"GeneOrGeneProduct"},{"id":"T29","span":{"begin":235,"end":266},"obj":"GeneOrGeneProduct"},{"id":"T28","span":{"begin":70,"end":75},"obj":"GeneOrGeneProduct"},{"id":"T27","span":{"begin":37,"end":42},"obj":"GeneOrGeneProduct"},{"id":"T12342","span":{"begin":118,"end":144},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T79355","span":{"begin":89,"end":117},"obj":"DiseaseOrPhenotypicFeature"},{"id":"T96215","span":{"begin":148,"end":152},"obj":"OrganismTaxon"}],"attributes":[{"id":"A6","pred":"#label","subj":"T12342","obj":"D015451"},{"id":"A5","pred":"#label","subj":"T79355","obj":"D015451"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}

{"project":"DisGeNET","denotations":[{"id":"T0","span":{"begin":37,"end":42},"obj":"gene:10010"},{"id":"T1","span":{"begin":89,"end":144},"obj":"disease:C1302547"},{"id":"T2","span":{"begin":37,"end":42},"obj":"gene:7186"},{"id":"T3","span":{"begin":89,"end":144},"obj":"disease:C1302547"},{"id":"T4","span":{"begin":70,"end":75},"obj":"gene:596"},{"id":"T5","span":{"begin":89,"end":144},"obj":"disease:C1302547"},{"id":"T6","span":{"begin":316,"end":340},"obj":"gene:10673"},{"id":"T7","span":{"begin":89,"end":144},"obj":"disease:C1302547"}],"relations":[{"id":"R1","pred":"associated_with","subj":"T0","obj":"T1"},{"id":"R2","pred":"associated_with","subj":"T2","obj":"T3"},{"id":"R3","pred":"associated_with","subj":"T4","obj":"T5"},{"id":"R4","pred":"associated_with","subj":"T6","obj":"T7"}],"namespaces":[{"prefix":"gene","uri":"http://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"disease","uri":"http://purl.bioontology.org/ontology/MEDLINEPLUS/"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}

{"project":"PubmedHPO","denotations":[{"id":"T5","span":{"begin":89,"end":117},"obj":"HP_0005550"},{"id":"T6","span":{"begin":109,"end":117},"obj":"HP_0001909"},{"id":"T7","span":{"begin":136,"end":144},"obj":"HP_0002665"},{"id":"T8","span":{"begin":235,"end":243},"obj":"HP_0001417"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}

{"project":"DisGeNET5_gene_disease","denotations":[{"id":"22711886-10#37#42#gene7186","span":{"begin":37,"end":42},"obj":"gene7186"},{"id":"22711886-10#70#75#gene596","span":{"begin":70,"end":75},"obj":"gene596"},{"id":"22711886-10#316#340#gene10673","span":{"begin":316,"end":340},"obj":"gene10673"},{"id":"22711886-10#89#144#diseaseC1302547","span":{"begin":89,"end":144},"obj":"diseaseC1302547"}],"relations":[{"id":"37#42#gene718689#144#diseaseC1302547","pred":"associated_with","subj":"22711886-10#37#42#gene7186","obj":"22711886-10#89#144#diseaseC1302547"},{"id":"70#75#gene59689#144#diseaseC1302547","pred":"associated_with","subj":"22711886-10#70#75#gene596","obj":"22711886-10#89#144#diseaseC1302547"},{"id":"316#340#gene1067389#144#diseaseC1302547","pred":"associated_with","subj":"22711886-10#316#340#gene10673","obj":"22711886-10#89#144#diseaseC1302547"}],"text":"Altogether, our results suggest that TRAF2 deficiency cooperates with BCL-2 in promoting chronic lymphocytic leukemia/small lymphocytic lymphoma in mice, possibly by specifically enforcing marginal zone B cell accumulation, increasing X-linked inhibitor of apoptosis expression, and rendering B cells independent of B cell activating factor for survival."}