PubMed:2105528 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PubMed/sourceid/2105528","sourcedb":"PubMed","sourceid":"2105528","source_url":"http://www.ncbi.nlm.nih.gov/pubmed/2105528","text":"Two distinct transcription factors that bind the immunoglobulin enhancer microE5/kappa 2 motif.\nActivity of the immunoglobulin heavy and kappa light chain gene enhancers depends on a complex interplay of ubiquitous and developmentally regulated proteins. Two complementary DNAs were isolated that encode proteins, denoted ITF-1 and ITF-2, that are expressed in a variety of cell types and bind the microE5/kappa 2 motif found in both heavy and kappa light chain enhancers. The complementary DNAs are the products of distinct genes, yet both ITF-1 and ITF-2 are structurally and functionally similar. 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