PubMed:2088505 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T1	8-30	protein	denotes	T-cell trans-activator
T2	49-80	DNA	denotes	phorbol ester-inducible element
T3	88-110	DNA	denotes	interleukin-2 promoter
T4	116-150	DNA	denotes	interleukin 2 (IL-2) gene promoter
T5	176-236	protein	denotes	cell-type-specific and ubiquitous transcriptional regulators
T6	316-320	protein	denotes	IL-2
T7	336-342	cell_type	denotes	T-cell
T8	472-519	protein	denotes	novel T-cell-specific transcriptional activator
T9	520-525	protein	denotes	TCF-1
T10	531-546	protein	denotes	T-Cell Factor-1
T11	568-600	DNA	denotes	T-cell-specific response element
T12	602-605	DNA	denotes	TCE
T13	626-639	DNA	denotes	IL-2 promoter
T14	654-657	DNA	denotes	TCE
T15	686-711	DNA	denotes	consensus NF kappa B site
T16	744-749	protein	denotes	TCF-1
T17	767-777	protein	denotes	NF kappa B
T18	793-803	protein	denotes	NF kappa B
T19	805-810	protein	denotes	TCF-1

Id	Subject	Object	Predicate	Lexical cue
S1	0-111	Sentence	denotes	A novel T-cell trans-activator that recognizes a phorbol ester-inducible element of the interleukin-2 promoter.
S2	112-354	Sentence	denotes	The interleukin 2 (IL-2) gene promoter is recognized by several cell-type-specific and ubiquitous transcriptional regulators that integrate information transmitted by various signaling systems leading to IL-2 production and T-cell activation.
S3	355-640	Sentence	denotes	Using a combination of transfection, protein-DNA binding, and in vitro transcription methods, we have discovered the novel T-cell-specific transcriptional activator TCF-1 (for T-Cell Factor-1), which recognizes a T-cell-specific response element (TCE) located within the IL-2 promoter.
S4	641-778	Sentence	denotes	Although the TCE is similar in sequence to a consensus NF kappa B site, several criteria indicate that TCF-1 is distinct from NF kappa B.
S5	779-877	Sentence	denotes	However, like NF kappa B, TCF-1 activity is induced by phorbol esters and other T-cell activators.

Id	Subject	Object	Predicate	Lexical cue
C1	0-30	NP	denotes	A novel T-cell trans-activator
C2	31-35	NP	denotes	that
C3	84-110	NP	denotes	the interleukin-2 promoter
C4	112-150	NP	denotes	The interleukin 2 (IL-2) gene promoter
C5	168-236	NP	denotes	several cell-type-specific and ubiquitous transcriptional regulators
C6	237-241	NP	denotes	that
C7	468-547	NP	denotes	the novel T-cell-specific transcriptional activator TCF-1 (for T-Cell Factor-1)
C8	549-554	NP	denotes	which
C9	566-606	NP	denotes	a T-cell-specific response element (TCE)
C10	622-639	NP	denotes	the IL-2 promoter
C11	650-657	NP	denotes	the TCE
C12	744-749	NP	denotes	TCF-1
C13	767-777	NP	denotes	NF kappa B
C14	793-803	NP	denotes	NF kappa B
R1	C2	C1	coref-relat	that,A novel T-cell trans-activator
R2	C4	C3	coref-relat	The interleukin 2 (IL-2) gene promoter,the interleukin-2 promoter
R3	C6	C5	coref-relat	that,several cell-type-specific and ubiquitous transcriptional regulators
R4	C8	C7	coref-relat	which,the novel T-cell-specific transcriptional activator TCF-1 (for T-Cell Factor-1)
R5	C10	C3	coref-ident	the IL-2 promoter,the interleukin-2 promoter
R6	C11	C9	coref-ident	the TCE,a T-cell-specific response element (TCE)
R7	C12	C7	coref-ident	TCF-1,the novel T-cell-specific transcriptional activator TCF-1 (for T-Cell Factor-1)
R8	C14	C13	coref-ident	NF kappa B,NF kappa B

Id	Subject	Object	Predicate	Lexical cue
T1	8-30	protein_family_or_group	denotes	T-cell trans-activator
T2	49-80	DNA_domain_or_region	denotes	phorbol ester-inducible element
T3	88-101	protein_molecule	denotes	interleukin-2
T4	116-129	protein_molecule	denotes	interleukin 2
T5	131-135	protein_molecule	denotes	IL-2
T6	316-320	protein_molecule	denotes	IL-2
T7	336-342	cell_type	denotes	T-cell
T8	378-390	other_name	denotes	transfection
T9	417-447	other_name	denotes	in vitro transcription methods
T10	472-519	protein_family_or_group	denotes	novel T-cell-specific transcriptional activator
T11	520-525	protein_molecule	denotes	TCF-1
T12	531-546	protein_molecule	denotes	T-Cell Factor-1
T13	568-600	DNA_domain_or_region	denotes	T-cell-specific response element
T14	602-605	DNA_domain_or_region	denotes	TCE
T15	626-630	protein_molecule	denotes	IL-2
T16	654-657	DNA_domain_or_region	denotes	TCE
T17	686-695	DNA_domain_or_region	denotes	consensus
T18	696-706	protein_molecule	denotes	NF kappa B
T19	744-749	protein_molecule	denotes	TCF-1
T20	767-777	protein_molecule	denotes	NF kappa B
T21	793-803	protein_molecule	denotes	NF kappa B
T22	805-810	protein_molecule	denotes	TCF-1
T23	834-848	other_organic_compound	denotes	phorbol esters
T24	859-876	other_name	denotes	T-cell activators