PubMed:18674790 / 0-563
Annnotations
LitCoin-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-88 | Sentence | denotes | High fat diet-fed obese rats are highly sensitive to doxorubicin-induced cardiotoxicity. |
| T2 | 89-222 | Sentence | denotes | Often, chemotherapy by doxorubicin (Adriamycin) is limited due to life threatening cardiotoxicity in patients during and posttherapy. |
| T3 | 223-341 | Sentence | denotes | Recently, we have shown that moderate diet restriction remarkably protects against doxorubicin-induced cardiotoxicity. |
| T4 | 342-528 | Sentence | denotes | This cardioprotection is accompanied by decreased cardiac oxidative stress and triglycerides and increased cardiac fatty-acid oxidation, ATP synthesis, and upregulated JAK/STAT3 pathway. |
LitCoin-entities-OrganismTaxon-PD
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| T1 | 24-28 | OrganismTaxon | denotes | rats | NCBItxid:10118|NCBItxid:10116|NCBItxid:10114 |
LitCoin-entities
| Id | Subject | Object | Predicate | Lexical cue | db_id |
|---|---|---|---|---|---|
| 5381 | 5-8 | ChemicalEntity | denotes | fat | MESH:D004041 |
| 5382 | 18-23 | DiseaseOrPhenotypicFeature | denotes | obese | MESH:D009765 |
| 5383 | 24-28 | OrganismTaxon | denotes | rats | NCBITaxon:10116 |
| 5384 | 53-64 | ChemicalEntity | denotes | doxorubicin | MESH:D004317 |
| 5385 | 73-87 | DiseaseOrPhenotypicFeature | denotes | cardiotoxicity | MESH:D066126 |
| 5386 | 112-123 | ChemicalEntity | denotes | doxorubicin | MESH:D004317 |
| 5387 | 125-135 | ChemicalEntity | denotes | Adriamycin | MESH:D004317 |
| 5388 | 172-186 | DiseaseOrPhenotypicFeature | denotes | cardiotoxicity | MESH:D066126 |
| 5389 | 306-317 | ChemicalEntity | denotes | doxorubicin | MESH:D004317 |
| 5390 | 326-340 | DiseaseOrPhenotypicFeature | denotes | cardiotoxicity | MESH:D066126 |
| 5391 | 421-434 | ChemicalEntity | denotes | triglycerides | MESH:D014280 |
| 5392 | 457-467 | ChemicalEntity | denotes | fatty-acid | MESH:D005227 |
| 5393 | 479-482 | ChemicalEntity | denotes | ATP | MESH:D000255 |
| 5394 | 510-513 | GeneOrGeneProduct | denotes | JAK | NCBIGene:84598 |
| 5395 | 514-519 | GeneOrGeneProduct | denotes | STAT3 | NCBIGene:25125 |
LitCoin-GeneOrGeneProduct-v2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 18-23 | GeneOrGeneProduct | denotes | obese |
| T2 | 140-147 | GeneOrGeneProduct | denotes | limited |
| T3 | 421-434 | GeneOrGeneProduct | denotes | triglycerides |
| T4 | 463-467 | GeneOrGeneProduct | denotes | acid |
| T5 | 514-519 | GeneOrGeneProduct | denotes | STAT3 |
LitCoin-GeneOrGeneProduct-v0
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 0-4 | GeneOrGeneProduct | denotes | High |
| T2 | 18-23 | GeneOrGeneProduct | denotes | obese |
| T3 | 33-39 | GeneOrGeneProduct | denotes | highly |
| T4 | 65-72 | GeneOrGeneProduct | denotes | induced |
| T5 | 140-147 | GeneOrGeneProduct | denotes | limited |
| T6 | 318-325 | GeneOrGeneProduct | denotes | induced |
| T7 | 421-434 | GeneOrGeneProduct | denotes | triglycerides |
| T8 | 457-462 | GeneOrGeneProduct | denotes | fatty |
| T9 | 463-467 | GeneOrGeneProduct | denotes | acid |
| T10 | 479-482 | GeneOrGeneProduct | denotes | ATP |
| T11 | 514-519 | GeneOrGeneProduct | denotes | STAT3 |
LitCoin-Disease-MeSH
| Id | Subject | Object | Predicate | Lexical cue | originalLabel |
|---|---|---|---|---|---|
| T1 | 18-23 | DiseaseOrPhenotypicFeature | denotes | obese | DISEASE |
| T2 | 73-87 | DiseaseOrPhenotypicFeature | denotes | cardiotoxicity | D066126 |
| T3 | 172-186 | DiseaseOrPhenotypicFeature | denotes | cardiotoxicity | D066126 |
| T4 | 326-340 | DiseaseOrPhenotypicFeature | denotes | cardiotoxicity | D066126 |
LitCoin-GeneOrGeneProduct-v3
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 514-519 | GeneOrGeneProduct | denotes | STAT3 |
LitCoin_Mondo_095
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T1 | 14-17 | DiseaseOrPhenotypicFeature | denotes | fed | 0007620 |
| T2 | 40-49 | DiseaseOrPhenotypicFeature | denotes | sensitive | 0000605 |
LitCoin-MeSH-Disease-2
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 18-23 | DiseaseOrPhenotypicFeature | denotes | obese | DISEASE |
| T2 | 73-87 | DiseaseOrPhenotypicFeature | denotes | cardiotoxicity | D066126 |
| T3 | 172-186 | DiseaseOrPhenotypicFeature | denotes | cardiotoxicity | D066126 |
| T4 | 326-340 | DiseaseOrPhenotypicFeature | denotes | cardiotoxicity | D066126 |
LitCoin-MONDO_bioort2019
| Id | Subject | Object | Predicate | Lexical cue | #label |
|---|---|---|---|---|---|
| T1 | 18-23 | DiseaseOrPhenotypicFeature | denotes | obese | DISEASE |
| T2 | 73-87 | DiseaseOrPhenotypicFeature | denotes | cardiotoxicity | D066126 |
| T3 | 172-186 | DiseaseOrPhenotypicFeature | denotes | cardiotoxicity | D066126 |
| T4 | 326-340 | DiseaseOrPhenotypicFeature | denotes | cardiotoxicity | D066126 |
LitCoin-Chemical-MeSH-CHEBI
| Id | Subject | Object | Predicate | Lexical cue | ID: |
|---|---|---|---|---|---|
| T1 | 53-64 | ChemicalEntity | denotes | doxorubicin | D004317|http://purl.obolibrary.org/obo/CHEBI_64816|http://purl.obolibrary.org/obo/CHEBI_28748 |
| T4 | 112-123 | ChemicalEntity | denotes | doxorubicin | D004317|http://purl.obolibrary.org/obo/CHEBI_64816|http://purl.obolibrary.org/obo/CHEBI_28748 |
| T7 | 125-135 | ChemicalEntity | denotes | Adriamycin | http://purl.obolibrary.org/obo/CHEBI_28748 |
| T8 | 306-317 | ChemicalEntity | denotes | doxorubicin | D004317|http://purl.obolibrary.org/obo/CHEBI_64816|http://purl.obolibrary.org/obo/CHEBI_28748 |
| T11 | 421-434 | ChemicalEntity | denotes | triglycerides | D014280|http://purl.obolibrary.org/obo/CHEBI_17855 |
| T13 | 479-482 | ChemicalEntity | denotes | ATP | http://purl.obolibrary.org/obo/CHEBI_30616|http://purl.obolibrary.org/obo/CHEBI_15422 |
LitCoin-NCBITaxon-2
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 24-28 | OrganismTaxon | denotes | rats |
| T2 | 190-198 | OrganismTaxon | denotes | patients |
LitCoin-training-merged
| Id | Subject | Object | Predicate | Lexical cue | #label | ID: |
|---|---|---|---|---|---|---|
| T13 | 479-482 | ChemicalEntity | denotes | ATP | http://purl.obolibrary.org/obo/CHEBI_15422|http://purl.obolibrary.org/obo/CHEBI_30616 | |
| T11 | 421-434 | ChemicalEntity | denotes | triglycerides | http://purl.obolibrary.org/obo/CHEBI_17855|D014280 | |
| T8 | 306-317 | ChemicalEntity | denotes | doxorubicin | http://purl.obolibrary.org/obo/CHEBI_28748|http://purl.obolibrary.org/obo/CHEBI_64816|D004317 | |
| T7 | 125-135 | ChemicalEntity | denotes | Adriamycin | http://purl.obolibrary.org/obo/CHEBI_28748 | |
| T4 | 112-123 | ChemicalEntity | denotes | doxorubicin | http://purl.obolibrary.org/obo/CHEBI_28748|http://purl.obolibrary.org/obo/CHEBI_64816|D004317 | |
| T1 | 53-64 | ChemicalEntity | denotes | doxorubicin | http://purl.obolibrary.org/obo/CHEBI_28748|http://purl.obolibrary.org/obo/CHEBI_64816|D004317 | |
| T7633 | 514-519 | GeneOrGeneProduct | denotes | STAT3 | ||
| T93175 | 326-340 | DiseaseOrPhenotypicFeature | denotes | cardiotoxicity | D066126 | |
| T4968 | 172-186 | DiseaseOrPhenotypicFeature | denotes | cardiotoxicity | D066126 | |
| T50358 | 73-87 | DiseaseOrPhenotypicFeature | denotes | cardiotoxicity | D066126 | |
| T92405 | 18-23 | DiseaseOrPhenotypicFeature | denotes | obese | DISEASE | |
| T88270 | 190-198 | OrganismTaxon | denotes | patients | ||
| T37219 | 24-28 | OrganismTaxon | denotes | rats |