PubMed:16574813 / 465-875
Annnotations
PubmedHPO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T3 | 143-148 | HP_0002664 | denotes | tumor |
uniprot-human
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 217-221 | http://www.uniprot.org/uniprot/P60484 | denotes | PTEN |
| T7 | 160-190 | http://www.uniprot.org/uniprot/P60484 | denotes | phosphatase and tensin homolog |
| T29 | 303-305 | http://www.uniprot.org/uniprot/Q86U18 | denotes | PI |
| T34 | 303-305 | http://www.uniprot.org/uniprot/P01298 | denotes | PI |
| T38 | 29-33 | http://www.uniprot.org/uniprot/Q13301 | denotes | MDM2 |
| T39 | 348-352 | http://www.uniprot.org/uniprot/Q13301 | denotes | MDM2 |
| T40 | 397-401 | http://www.uniprot.org/uniprot/Q13301 | denotes | MDM2 |
uniprot-mouse
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T19 | 160-190 | http://www.uniprot.org/uniprot/O08586 | denotes | phosphatase and tensin homolog |
GlycoBiology-NCBITAXON
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T4 | 127-137 | http://purl.bioontology.org/ontology/NCBITAXON/127244 | denotes | mechanisms |
GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 143-159 | http://purl.obolibrary.org/obo/GO_0051726 | denotes | tumor suppressor |
| T14 | 160-171 | http://purl.obolibrary.org/obo/GO_0016791 | denotes | phosphatase |
| T15 | 243-254 | http://purl.obolibrary.org/obo/GO_0016791 | denotes | phosphatase |
| T16 | 310-323 | http://purl.obolibrary.org/obo/GO_0043491 | denotes | AKT signaling |
| T19 | 314-323 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
GO-CC
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T8 | 160-190 | http://purl.obolibrary.org/obo/GO_1990455 | denotes | phosphatase and tensin homolog |
| T9 | 202-212 | http://purl.obolibrary.org/obo/GO_0005694 | denotes | chromosome |
EDAM-topics
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T9 | 9-16 | http://edamontology.org/topic_3678 | denotes | studies |
| T10 | 202-212 | http://edamontology.org/topic_0624 | denotes | chromosome |
| T11 | 202-212 | http://edamontology.org/topic_0654 | denotes | chromosome |
| T12 | 402-409 | http://edamontology.org/topic_0078 | denotes | protein |
EDAM-DFO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 402-409 | http://edamontology.org/data_1467 | denotes | protein |
| T3 | 402-409 | http://edamontology.org/format_1208 | denotes | protein |
DisGeNET5_gene_disease
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 16574813-3#29#33#gene4193 | 29-33 | gene4193 | denotes | MDM2 |
| 16574813-3#66#79#diseaseC0596263 | 66-79 | diseaseC0596263 | denotes | tumorigenesis |
| 29#33#gene419366#79#diseaseC0596263 | 16574813-3#29#33#gene4193 | 16574813-3#66#79#diseaseC0596263 | associated_with | MDM2,tumorigenesis |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T4 | 0-410 | Sentence | denotes | Previous studies showed that MDM2 is an oncoprotein that controls tumorigenesis through both p53-dependent and p53-independent mechanisms, and tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a dual-specificity phosphatase that antagonizes phosphatidylinositol 3-kinase (PI-3K)/AKT signaling, is capable of blocking MDM2 nuclear translocation and destabilizing the MDM2 protein. |
| T4 | 0-410 | Sentence | denotes | Previous studies showed that MDM2 is an oncoprotein that controls tumorigenesis through both p53-dependent and p53-independent mechanisms, and tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a dual-specificity phosphatase that antagonizes phosphatidylinositol 3-kinase (PI-3K)/AKT signaling, is capable of blocking MDM2 nuclear translocation and destabilizing the MDM2 protein. |
| T4 | 0-410 | Sentence | denotes | Previous studies showed that MDM2 is an oncoprotein that controls tumorigenesis through both p53-dependent and p53-independent mechanisms, and tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a dual-specificity phosphatase that antagonizes phosphatidylinositol 3-kinase (PI-3K)/AKT signaling, is capable of blocking MDM2 nuclear translocation and destabilizing the MDM2 protein. |
DisGeNET
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T0 | 29-33 | gene:4193 | denotes | MDM2 |
| T1 | 66-79 | disease:C0596263 | denotes | tumorigenesis |
| R1 | T0 | T1 | associated_with | MDM2,tumorigenesis |
mondo_disease
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T4 | 143-148 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
GlyCosmos15-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T4 | 143-148 | Phenotype | denotes | tumor | HP:0002664 |
GlyCosmos15-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T4 | 143-148 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
GlyCosmos15-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T2 | 202-212 | Body_part | denotes | chromosome | http://purl.obolibrary.org/obo/GO_0005694 |
sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| TextSentencer_T4 | 0-410 | Sentence | denotes | Previous studies showed that MDM2 is an oncoprotein that controls tumorigenesis through both p53-dependent and p53-independent mechanisms, and tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a dual-specificity phosphatase that antagonizes phosphatidylinositol 3-kinase (PI-3K)/AKT signaling, is capable of blocking MDM2 nuclear translocation and destabilizing the MDM2 protein. |
| T4 | 0-410 | Sentence | denotes | Previous studies showed that MDM2 is an oncoprotein that controls tumorigenesis through both p53-dependent and p53-independent mechanisms, and tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a dual-specificity phosphatase that antagonizes phosphatidylinositol 3-kinase (PI-3K)/AKT signaling, is capable of blocking MDM2 nuclear translocation and destabilizing the MDM2 protein. |
| T4 | 0-410 | Sentence | denotes | Previous studies showed that MDM2 is an oncoprotein that controls tumorigenesis through both p53-dependent and p53-independent mechanisms, and tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a dual-specificity phosphatase that antagonizes phosphatidylinositol 3-kinase (PI-3K)/AKT signaling, is capable of blocking MDM2 nuclear translocation and destabilizing the MDM2 protein. |
GlyCosmos15-Sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T4 | 0-410 | Sentence | denotes | Previous studies showed that MDM2 is an oncoprotein that controls tumorigenesis through both p53-dependent and p53-independent mechanisms, and tumor suppressor phosphatase and tensin homolog deleted on chromosome 10 (PTEN), a dual-specificity phosphatase that antagonizes phosphatidylinositol 3-kinase (PI-3K)/AKT signaling, is capable of blocking MDM2 nuclear translocation and destabilizing the MDM2 protein. |
Anatomy-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T2 | 202-212 | Body_part | denotes | chromosome | http://purl.obolibrary.org/obo/GO_0005694 |
HP-phenotype
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T4 | 143-148 | Phenotype | denotes | tumor | HP:0002664 |