PubMed:16371368 / 2033-2292
Annnotations
sonoma2
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T-76 | 62-70 | POSREG | denotes | elevated |
T-77 | 71-89 | MPA | denotes | catalytic activity |
T-78 | 103-110 | REG | denotes | changes |
T-79 | 138-150 | INTERACTION | denotes | interactions |
T-80 | 159-162 | POSREG | denotes | GOF |
T-81 | 170-175 | GENE | denotes | SHP-2 |
T-82 | 204-208 | REG | denotes | play |
T-83 | 222-226 | REG | denotes | role |
R-94 | T-81 | T-79 | ThemeOf | SHP-2,interactions |
R-95 | T-83 | T-82 | ThemeOf | role,play |
R-91 | T-77 | T-76 | ThemeOf | catalytic activity,elevated |
R-92 | T-79 | T-78 | ThemeOf | interactions,changes |
R-93 | T-79 | T-80 | ThemeOf | interactions,GOF |
sonoma
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T-81 | 62-70 | POSREG | denotes | elevated |
T-82 | 71-89 | MPA | denotes | catalytic activity |
T-83 | 103-110 | REG | denotes | changes |
T-84 | 163-169 | VAR | denotes | mutant |
T-85 | 170-175 | GENE | denotes | SHP-2 |
T-86 | 204-208 | REG | denotes | play |
T-87 | 222-226 | REG | denotes | role |
T-88 | 230-243 | GENE | denotes | SHP-2-related |
T-89 | 244-258 | DISEASE | denotes | leukemigenesis |
R-151 | T-81 | T-82 | ThemeOf | elevated,catalytic activity |
R-152 | T-81 | T-83 | CauseOf | elevated,changes |
R-153 | T-81 | T-84 | CauseOf | elevated,mutant |
R-154 | T-81 | T-86 | CauseOf | elevated,play |
R-155 | T-82 | T-83 | ThemeOf | catalytic activity,changes |
R-156 | T-83 | T-84 | CauseOf | changes,mutant |
R-157 | T-83 | T-85 | ThemeOf | changes,SHP-2 |
R-158 | T-83 | T-86 | CauseOf | changes,play |
R-159 | T-83 | T-87 | CauseOf | changes,role |
R-160 | T-83 | T-88 | CauseOf | changes,SHP-2-related |
R-161 | T-83 | T-89 | ThemeOf | changes,leukemigenesis |
R-162 | T-84 | T-85 | ThemeOf | mutant,SHP-2 |
R-163 | T-84 | T-86 | CauseOf | mutant,play |
R-164 | T-84 | T-87 | CauseOf | mutant,role |
R-165 | T-85 | T-86 | ThemeOf | SHP-2,play |
R-166 | T-85 | T-87 | ThemeOf | SHP-2,role |
R-167 | T-86 | T-87 | ThemeOf | play,role |
R-168 | T-86 | T-88 | CauseOf | play,SHP-2-related |
R-169 | T-86 | T-89 | ThemeOf | play,leukemigenesis |
R-170 | T-87 | T-88 | ThemeOf | role,SHP-2-related |
R-171 | T-87 | T-89 | ThemeOf | role,leukemigenesis |
sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T12 | 0-259 | Sentence | denotes | Taken together, these studies suggest that in addition to the elevated catalytic activity, fundamental changes in physical and functional interactions between GOF mutant SHP-2 and signaling partners also play an important role in SHP-2-related leukemigenesis. |