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PubMed:1520341 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 36-40 protein denotes AP-1
T2 42-52 protein denotes NF-kappa B
T3 58-85 protein denotes tumor necrosis factor-alpha
T4 89-108 cell_type denotes human B lymphocytes
T5 123-142 cell_type denotes human B lymphocytes
T6 206-227 protein denotes phosphatases 1 and 2A
T7 262-282 protein denotes transcription factor
T8 284-288 protein denotes AP-1
T9 314-324 protein denotes NF-kappa B
T10 377-401 protein denotes octamer binding proteins
T11 403-408 protein denotes Oct-1
T12 412-417 protein denotes Oct-2
T13 442-446 protein denotes AP-1
T14 451-461 protein denotes NF-kappa B
T15 521-565 DNA denotes tumor necrosis factor-alpha (TNF-alpha) gene
T16 609-623 RNA denotes TNF-alpha mRNA
T17 695-709 RNA denotes TNF-alpha mRNA
T18 769-778 protein denotes TNF-alpha
T19 878-882 protein denotes AP-1
T20 887-897 protein denotes NF-kappa B
T21 947-961 protein denotes immunoglobulin

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 0-12 NP denotes Okadaic acid
C2 36-40 NP denotes AP-1
C3 42-52 NP denotes NF-kappa B
C4 58-85 NP denotes tumor necrosis factor-alpha
C5 89-108 NP denotes human B lymphocytes
C6 123-142 NP denotes human B lymphocytes
C7 176-188 NP denotes okadaic acid
C8 190-227 NP denotes an inhibitor of phosphatases 1 and 2A
C9 258-282 NP denotes the transcription factor
C10 284-288 NP denotes AP-1
C11 314-324 NP denotes NF-kappa B
C12 373-401 NP denotes the octamer binding proteins
C13 403-417 NP denotes Oct-1 or Oct-2
C14 442-446 NP denotes AP-1
C15 451-461 NP denotes NF-kappa B
C16 521-560 NP denotes tumor necrosis factor-alpha (TNF-alpha)
C17 593-605 NP denotes okadaic acid
C18 609-618 NP denotes TNF-alpha
C19 647-659 NP denotes okadaic acid
C20 695-704 NP denotes TNF-alpha
C21 769-778 NP denotes TNF-alpha
C22 826-838 NP denotes okadaic acid
C23 878-882 NP denotes AP-1
C24 887-897 NP denotes NF-kappa B
C25 898-900 NP denotes it
R1 C6 C5 coref-ident human B lymphocytes,human B lymphocytes
R2 C7 C1 coref-ident okadaic acid,Okadaic acid
R3 C8 C7 coref-appos an inhibitor of phosphatases 1 and 2A,okadaic acid
R4 C9 C2 coref-ident the transcription factor,AP-1
R5 C10 C9 coref-appos AP-1,the transcription factor
R6 C11 C3 coref-ident NF-kappa B,NF-kappa B
R7 C13 C12 coref-appos Oct-1 or Oct-2,the octamer binding proteins
R8 C14 C10 coref-ident AP-1,AP-1
R9 C15 C11 coref-ident NF-kappa B,NF-kappa B
R10 C16 C4 coref-ident tumor necrosis factor-alpha (TNF-alpha),tumor necrosis factor-alpha
R11 C17 C7 coref-ident okadaic acid,okadaic acid
R12 C18 C16 coref-ident TNF-alpha,tumor necrosis factor-alpha (TNF-alpha)
R13 C19 C17 coref-ident okadaic acid,okadaic acid
R14 C20 C18 coref-ident TNF-alpha,TNF-alpha
R15 C21 C20 coref-ident TNF-alpha,TNF-alpha
R16 C22 C19 coref-ident okadaic acid,okadaic acid
R17 C23 C14 coref-ident AP-1,AP-1
R18 C24 C15 coref-ident NF-kappa B,NF-kappa B
R19 C25 C22 coref-pron it,okadaic acid

semrep-sample

Id Subject Object Predicate Lexical cue
E1-ti-1 0-12 cui:C0069389 denotes Okadaic acid
E2-ti-1 18-24 cui:C0237399 denotes potent
E3-ti-1 36-40 cui:C0002059 denotes AP-1
E4-ti-1 42-52 cui:C0079904 denotes NF-kappa B
E5-ti-1 58-85 cui:C1448177 denotes tumor necrosis factor-alpha
E6-ti-1 89-94 cui:C0020114 denotes human
E7-ti-1 95-108 cui:C0004561 denotes B lymphocytes
T1 25-32 STIMULATES denotes inducer
T2 89-108 PART_OF denotes human B lymphocytes
T3 86-88 LOCATION_OF denotes in
T4 86-88 LOCATION_OF denotes in
E1-ab-1 110-119 cui:C0087111 denotes Treatment
E2-ab-1 123-128 cui:C0020114 denotes human
E3-ab-1 129-142 cui:C0004561 denotes B lymphocytes
E4-ab-1 176-188 cui:C0069389 denotes okadaic acid
E5-ab-1 193-202 cui:C0243077 denotes inhibitor
E6-ab-1 206-218 cui:C0031678 denotes phosphatases
E7-ab-1 245-254 cui:C0857127 denotes induction
E8-ab-1 262-282 cui:C0040648 denotes transcription factor
E9-ab-1 284-288 cui:C0002059 denotes AP-1
E10-ab-1 295-301 cui:C0522501 denotes marked
E11-ab-1 302-310 cui:C0442805 denotes increase
E12-ab-1 314-324 cui:C0079904 denotes NF-kappa B
E13-ab-1 325-331 cui:C0441889 denotes levels
T5 123-142 PART_OF denotes human B lymphocytes
T6 245-254 STIMULATES denotes induction
T7 302-310 STIMULATES denotes increase
E1-ab-2 349-355 cui:C1280500 denotes effect
E2-ab-2 363-369 cui:C0441889 denotes levels
E3-ab-2 385-401 cui:C0242210 denotes binding proteins
E4-ab-2 403-408 cui:C1442824 denotes Oct-1
E5-ab-2 412-417 cui:C1442823 denotes Oct-2
E1-ab-3 442-446 cui:C0002059 denotes AP-1
E2-ab-3 451-461 cui:C0079904 denotes NF-kappa B
E3-ab-3 504-513 cui:C0857127 denotes induction
E4-ab-3 543-548 cui:C0439095 denotes alpha
E5-ab-3 521-565 cui:C0812246 denotes tumor necrosis factor-alpha (TNF-alpha) gene
E6-ab-3 582-589 cui:C1280500 denotes effects
E7-ab-3 593-605 cui:C0069389 denotes okadaic acid
E8-ab-3 609-618 cui:C1448177 denotes TNF-alpha
E9-ab-3 619-623 cui:C0035696 denotes mRNA
E10-ab-3 624-630 cui:C0441889 denotes levels
T8 504-513 STIMULATES denotes induction
T9 582-589 INTERACTS_WITH denotes effects
E1-ab-4 632-641 cui:C0087111 denotes Treatment
E2-ab-4 647-659 cui:C0069389 denotes okadaic acid
E3-ab-4 683-691 cui:C0442805 denotes increase
E4-ab-4 695-704 cui:C1448177 denotes TNF-alpha
E5-ab-4 705-709 cui:C0035696 denotes mRNA
E6-ab-4 710-721 cui:C1519595 denotes transcripts
E7-ab-4 736-747 cui:C1292856 denotes stimulation
E8-ab-4 752-757 cui:C0549177 denotes large
E9-ab-4 758-765 cui:C1265611 denotes amounts
E10-ab-4 769-778 cui:C1448177 denotes TNF-alpha
E11-ab-4 802-815 cui:C0010454 denotes culture media
E1-ab-5 826-838 cui:C0069389 denotes okadaic acid
E2-ab-5 850-856 cui:C0237399 denotes potent
E3-ab-5 878-882 cui:C0002059 denotes AP-1
E4-ab-5 887-897 cui:C0079904 denotes NF-kappa B
E5-ab-5 905-908 cui:C1518422 denotes not
E6-ab-5 923-943 cui:C1155008 denotes B cell proliferation
E7-ab-5 947-971 cui:C1327439 denotes immunoglobulin secretion
T10 909-915 CAUSES denotes induce
T11 909-915 CAUSES denotes induce
R1 E1-ti-1 T1 subjectOf Okadaic acid,inducer
R2 E3-ti-1 T1 objectOf AP-1,inducer
R3 E7-ti-1 T2 subjectOf B lymphocytes,human B lymphocytes
R4 E6-ti-1 T2 objectOf human,human B lymphocytes
R5 E7-ti-1 T3 subjectOf B lymphocytes,in
R6 E5-ti-1 T3 objectOf tumor necrosis factor-alpha,in
R7 E7-ti-1 T4 subjectOf B lymphocytes,in
R8 E4-ti-1 T4 objectOf NF-kappa B,in
R9 E3-ab-1 T5 subjectOf B lymphocytes,human B lymphocytes
R10 E2-ab-1 T5 objectOf human,human B lymphocytes
R11 E9-ab-1 T6 subjectOf AP-1,induction
R12 E8-ab-1 T6 objectOf transcription factor,induction
R13 E4-ab-1 T7 subjectOf okadaic acid,increase
R14 E12-ab-1 T7 objectOf NF-kappa B,increase
R15 E2-ab-3 T8 subjectOf NF-kappa B,induction
R16 E5-ab-3 T8 objectOf tumor necrosis factor-alpha (TNF-alpha) gene,induction
R17 E7-ab-3 T9 subjectOf okadaic acid,effects
R18 E8-ab-3 T9 objectOf TNF-alpha,effects
R19 E4-ab-5 T10 subjectOf NF-kappa B,induce
R20 E6-ab-5 T10 objectOf B cell proliferation,induce
R21 E4-ab-5 T11 subjectOf NF-kappa B,induce
R22 E7-ab-5 T11 objectOf immunoglobulin secretion,induce

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-109 Sentence denotes Okadaic acid is a potent inducer of AP-1, NF-kappa B, and tumor necrosis factor-alpha in human B lymphocytes.
S2 110-332 Sentence denotes Treatment of human B lymphocytes with an optimal concentration of okadaic acid, an inhibitor of phosphatases 1 and 2A, resulted in the induction of the transcription factor, AP-1 and a marked increase in NF-kappa B levels.
S3 333-430 Sentence denotes In contrast, no effect on the levels of the octamer binding proteins, Oct-1 or Oct-2, were found.
S4 431-631 Sentence denotes Since both AP-1 and NF-kappa B have been reported to be important in the induction of the tumor necrosis factor-alpha (TNF-alpha) gene we examined the effects of okadaic acid on TNF-alpha mRNA levels.
S5 632-816 Sentence denotes Treatment with okadaic acid resulted in a striking increase in TNF-alpha mRNA transcripts within 1 h of stimulation and large amounts of TNF-alpha were released into the culture media.
S6 817-972 Sentence denotes Although okadaic acid provides a potent inductive signal for AP-1 and NF-kappa B it did not induce either B cell proliferation or immunoglobulin secretion.

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-12 other_organic_compound denotes Okadaic acid
T2 36-40 protein_molecule denotes AP-1
T3 42-52 protein_molecule denotes NF-kappa B
T4 58-85 protein_molecule denotes tumor necrosis factor-alpha
T5 89-108 cell_type denotes human B lymphocytes
T6 123-142 cell_type denotes human B lymphocytes
T7 176-188 other_organic_compound denotes okadaic acid
T8 262-282 protein_family_or_group denotes transcription factor
T9 284-288 protein_molecule denotes AP-1
T10 314-324 protein_molecule denotes NF-kappa B
T11 377-401 protein_family_or_group denotes octamer binding proteins
T12 403-408 protein_molecule denotes Oct-1
T13 412-417 protein_molecule denotes Oct-2
T14 442-446 protein_molecule denotes AP-1
T15 451-461 protein_molecule denotes NF-kappa B
T16 521-548 protein_molecule denotes tumor necrosis factor-alpha
T17 593-605 other_organic_compound denotes okadaic acid
T18 609-623 RNA_molecule denotes TNF-alpha mRNA
T19 647-659 other_organic_compound denotes okadaic acid
T20 695-709 RNA_molecule denotes TNF-alpha mRNA
T21 769-778 protein_molecule denotes TNF-alpha
T22 802-815 other_name denotes culture media
T23 826-838 other_organic_compound denotes okadaic acid
T24 878-882 protein_molecule denotes AP-1
T25 887-897 protein_molecule denotes NF-kappa B
T26 923-943 other_name denotes B cell proliferation
T27 947-961 protein_family_or_group denotes immunoglobulin

metamap-sample

Id Subject Object Predicate Lexical cue
T1 124-129 C0086418 denotes uman
T2 90-95 C0086418 denotes uman
T3 130-143 C0004561 denotes lymphocytes
T4 96-109 C0004561 denotes lymphocytes.
T5 610-619 C1456820 denotes NF-alpha
T6 522-549 C1456820 denotes umor necrosis factor-alpha
T7 879-883 C0085828 denotes P-1
T8 443-447 C0085828 denotes P-1
T9 285-289 C0085828 denotes P-1
T10 37-41 C0085828 denotes P-1,
T11 888-898 C0079904 denotes F-kappa B
T12 452-462 C0079904 denotes F-kappa B
T13 315-325 C0079904 denotes F-kappa B
T14 43-53 C0079904 denotes F-kappa B,
T15 827-839 C0069389 denotes kadaic acid
T16 648-660 C0069389 denotes kadaic acid
T17 594-606 C0069389 denotes kadaic acid
T18 177-189 C0069389 denotes kadaic acid,
T19 1-13 C0069389 denotes kadaic acid
T20 81-86 C2003941 denotes lpha
T21 851-857 C3245505 denotes otent
T22 19-25 C3245505 denotes otent
T23 706-710 C0035696 denotes RNA
T24 620-624 C0035696 denotes RNA
T25 404-409 C1442824 denotes ct-1
T26 413-418 C1442823 denotes ct-2,
T27 675-683 C0038452 denotes triking
T28 625-631 C0441889 denotes evels.
T29 364-370 C0441889 denotes evels
T30 326-332 C0441889 denotes evels.
T31 263-283 C0040648 denotes ranscription factor,
T32 386-402 C0242210 denotes inding proteins,
T33 910-916 C0205263 denotes nduce
T34 246-255 C0205263 denotes nduction
T35 633-642 C0087111 denotes reatment
T36 111-120 C0087111 denotes reatment
T37 684-692 C0442805 denotes ncrease
T38 303-311 C0442805 denotes ncrease
T39 661-669 C2825142 denotes esulted
T40 230-238 C2825142 denotes esulted
T41 337-345 C1979874 denotes ontrast,
T42 570-578 C0332128 denotes xamined
T43 906-909 C1518422 denotes ot
T44 425-430 C0150312 denotes ound.
T45 730-733 C0700308 denotes h
T46 840-848 C1999230 denotes rovides
T47 473-481 C0684224 denotes eported
T48 737-748 C1292856 denotes timulation
T49 482-484 C1883351 denotes o
T50 924-944 C1155008 denotes cell proliferation
T51 160-173 C1446561 denotes oncentration
T52 711-722 C1519595 denotes ranscripts
T53 583-590 C1280500 denotes ffects
T54 347-356 C1301751 denotes o effect
T55 785-793 C1283071 denotes eleased
T56 759-766 C1265611 denotes mounts
T57 868-874 C1710082 denotes ignal
T58 152-159 C2698651 denotes ptimal
T59 753-758 C0549177 denotes arge
T60 296-302 C0522501 denotes arked