> top > docs > PubMed:11424320 > annotations

PubMed:11424320 JSONTXT

Annnotations TAB JSON ListView MergeView

Inflammaging

Id Subject Object Predicate Lexical cue
T1 0-52 Sentence denotes Staphylococcus aureus in inflammatory bowel disease.
T2 53-64 Sentence denotes BACKGROUND:
T3 65-232 Sentence denotes The potential role of superantigens in inflammatory bowel disease (IBD), particularly Crohn disease, has been broached in studies of the functions of T cell receptors.
T4 233-308 Sentence denotes Staphylococcal cells have been found in intestinal lymph follicles of IBDs.
T5 309-529 Sentence denotes To clarify a role of staphylococcal superantigens in IBD, we attempted to determine whether Staphylococcus aureus could be detected in intestinal mucosa, including surgical specimens and lymph follicles of initial cases.
T6 530-538 Sentence denotes METHODS:
T7 539-719 Sentence denotes One-hundred-and-six colonic and ileal specimens were obtained from 38 Crohn disease, 25 ulcerative colitis and 36 non-IBD patients through therapeutic surgery or endoscopic biopsy.
T8 720-817 Sentence denotes In Crohn disease, 23 surgical specimens and 11 biopsy specimens from initial cases were included.
T9 818-931 Sentence denotes DNA was extracted with phenol-chloroform after homogenization and proteinase K treatment in 73 mucosal specimens.
T10 932-1051 Sentence denotes Using an inverted microscope, lymph follicle tissue was microdissected from the remaining 33, mostly biopsy, specimens.
T11 1052-1093 Sentence denotes DNA was then extracted by freeze-thawing.
T12 1094-1150 Sentence denotes A coagulase gene characteristic of S. aureus was sought.
T13 1151-1262 Sentence denotes A nested polymerase chain reaction was performed utilizing primers that amplify a region of the coagulase gene.
T14 1263-1352 Sentence denotes Polymerase chain reaction products were analyzed with polyacrylamide gel electrophoresis.
T15 1353-1361 Sentence denotes RESULTS:
T16 1362-1513 Sentence denotes Only one surgically resected colonic specimen, from a 42-year-old male ulcerative colitis patient, registered positive staphylocoagulase amplification.
T17 1514-1526 Sentence denotes CONCLUSIONS:
T18 1527-1645 Sentence denotes Staphylococcal superantigens are not involved in either the early lesions or the established lesions of Crohn disease.
T19 1646-1723 Sentence denotes However, S. aureus infection occasionally may occur during the course of IBD.
T1 0-52 Sentence denotes Staphylococcus aureus in inflammatory bowel disease.
T2 53-64 Sentence denotes BACKGROUND:
T3 65-232 Sentence denotes The potential role of superantigens in inflammatory bowel disease (IBD), particularly Crohn disease, has been broached in studies of the functions of T cell receptors.
T4 233-308 Sentence denotes Staphylococcal cells have been found in intestinal lymph follicles of IBDs.
T5 309-529 Sentence denotes To clarify a role of staphylococcal superantigens in IBD, we attempted to determine whether Staphylococcus aureus could be detected in intestinal mucosa, including surgical specimens and lymph follicles of initial cases.
T6 530-538 Sentence denotes METHODS:
T7 539-719 Sentence denotes One-hundred-and-six colonic and ileal specimens were obtained from 38 Crohn disease, 25 ulcerative colitis and 36 non-IBD patients through therapeutic surgery or endoscopic biopsy.
T8 720-817 Sentence denotes In Crohn disease, 23 surgical specimens and 11 biopsy specimens from initial cases were included.
T9 818-931 Sentence denotes DNA was extracted with phenol-chloroform after homogenization and proteinase K treatment in 73 mucosal specimens.
T10 932-1051 Sentence denotes Using an inverted microscope, lymph follicle tissue was microdissected from the remaining 33, mostly biopsy, specimens.
T11 1052-1093 Sentence denotes DNA was then extracted by freeze-thawing.
T12 1094-1150 Sentence denotes A coagulase gene characteristic of S. aureus was sought.
T13 1151-1262 Sentence denotes A nested polymerase chain reaction was performed utilizing primers that amplify a region of the coagulase gene.
T14 1263-1352 Sentence denotes Polymerase chain reaction products were analyzed with polyacrylamide gel electrophoresis.
T15 1353-1361 Sentence denotes RESULTS:
T16 1362-1513 Sentence denotes Only one surgically resected colonic specimen, from a 42-year-old male ulcerative colitis patient, registered positive staphylocoagulase amplification.
T17 1514-1526 Sentence denotes CONCLUSIONS:
T18 1527-1645 Sentence denotes Staphylococcal superantigens are not involved in either the early lesions or the established lesions of Crohn disease.
T19 1646-1723 Sentence denotes However, S. aureus infection occasionally may occur during the course of IBD.

disease_gene_microbe_small

Id Subject Object Predicate Lexical cue
T0 25-51 DOID:0050589 denotes inflammatory bowel disease
T1 105-131 DOID:0050589 denotes nflammatory bowel disease
T2 152-165 DOID:8778 denotes rohn disease,
T3 610-623 DOID:8778 denotes rohn disease,
T4 628-646 DOID:8577 denotes lcerative colitis
T5 724-737 DOID:8778 denotes rohn disease,
T6 1434-1452 DOID:8577 denotes lcerative colitis
T7 1632-1645 DOID:8778 denotes rohn disease.
T8 0-21 taxonomy:1280 denotes Staphylococcus aureus
T9 234-248 taxonomy:1279 denotes taphylococcal
T10 331-345 taxonomy:1279 denotes taphylococcal
T11 402-423 taxonomy:1280 denotes taphylococcus aureus
T12 1130-1139 taxonomy:1280 denotes . aureus
T13 1528-1542 taxonomy:1279 denotes taphylococcal
T14 1656-1665 taxonomy:1280 denotes . aureus