PubMed:10426995
Annnotations
jnlpba-st-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 37-59 | protein | denotes | microbial lipoproteins |
| T2 | 68-87 | protein | denotes | toll-like receptors |
| T3 | 191-205 | protein | denotes | interleukin-12 |
| T4 | 207-212 | protein | denotes | IL-12 |
| T5 | 308-313 | protein | denotes | IL-12 |
| T6 | 328-339 | cell_type | denotes | macrophages |
| T7 | 419-441 | protein | denotes | microbial lipoproteins |
| T8 | 468-473 | protein | denotes | IL-12 |
| T9 | 494-505 | cell_type | denotes | macrophages |
| T10 | 541-560 | protein | denotes | Toll-like receptors |
| T11 | 562-566 | protein | denotes | TLRs |
| T12 | 642-663 | protein | denotes | nitric oxide synthase |
| T13 | 747-751 | protein | denotes | TLRs |
| T14 | 755-777 | protein | denotes | microbial lipoproteins |
genia-medco-coref
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| C20 | 37-59 | NP | denotes | microbial lipoproteins |
| C21 | 68-87 | NP | denotes | toll-like receptors |
| C1 | 191-213 | NP | denotes | interleukin-12 (IL-12) |
| C5 | 173-213 | NP | denotes | the production of interleukin-12 (IL-12) |
| C2 | 215-255 | NP | denotes | a key signal of the innate immune system |
| C3 | 282-295 | NP | denotes | the molecules |
| C4 | 296-300 | NP | denotes | that |
| C6 | 308-324 | NP | denotes | IL-12 production |
| C11 | 328-339 | NP | denotes | macrophages |
| C7 | 344-358 | NP | denotes | the mechanisms |
| C8 | 362-367 | NP | denotes | which |
| C9 | 368-372 | NP | denotes | they |
| C18 | 419-441 | NP | denotes | microbial lipoproteins |
| C10 | 468-484 | NP | denotes | IL-12 production |
| C12 | 488-505 | NP | denotes | human macrophages |
| C13 | 541-567 | NP | denotes | Toll-like receptors (TLRs) |
| C15 | 686-698 | NP | denotes | nitric oxide |
| C16 | 700-731 | NP | denotes | a powerful microbicidal pathway |
| C17 | 747-751 | NP | denotes | TLRs |
| C19 | 755-777 | NP | denotes | microbial lipoproteins |
| R1 | C2 | C1 | coref-appos | a key signal of the innate immune system,interleukin-12 (IL-12) |
| R2 | C4 | C3 | coref-relat | that,the molecules |
| R3 | C6 | C5 | coref-ident | IL-12 production,the production of interleukin-12 (IL-12) |
| R4 | C8 | C7 | coref-relat | which,the mechanisms |
| R5 | C9 | C3 | coref-pron | they,the molecules |
| R6 | C18 | C20 | coref-ident | microbial lipoproteins,microbial lipoproteins |
| R7 | C10 | C6 | coref-ident | IL-12 production,IL-12 production |
| R8 | C12 | C11 | coref-ident | human macrophages,macrophages |
| R9 | C13 | C21 | coref-ident | Toll-like receptors (TLRs),toll-like receptors |
| R10 | C16 | C15 | coref-appos | a powerful microbicidal pathway,nitric oxide |
| R11 | C17 | C13 | coref-ident | TLRs,Toll-like receptors (TLRs) |
| R12 | C19 | C18 | coref-ident | microbial lipoproteins,microbial lipoproteins |
pubmed-sentences-benchmark
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| S1 | 0-88 | Sentence | denotes | Host defense mechanisms triggered by microbial lipoproteins through toll-like receptors. |
| S2 | 89-256 | Sentence | denotes | The generation of cell-mediated immunity against many infectious pathogens involves the production of interleukin-12 (IL-12), a key signal of the innate immune system. |
| S3 | 257-396 | Sentence | denotes | Yet, for many pathogens, the molecules that induce IL-12 production by macrophages and the mechanisms by which they do so remain undefined. |
| S4 | 397-568 | Sentence | denotes | Here it is shown that microbial lipoproteins are potent stimulators of IL-12 production by human macrophages, and that induction is mediated by Toll-like receptors (TLRs). |
| S5 | 569-732 | Sentence | denotes | Several lipoproteins stimulated TLR-dependent transcription of inducible nitric oxide synthase and the production of nitric oxide, a powerful microbicidal pathway. |
| S6 | 733-846 | Sentence | denotes | Activation of TLRs by microbial lipoproteins may initiate innate defense mechanisms against infectious pathogens. |
GENIAcorpus
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T1 | 37-59 | protein_family_or_group | denotes | microbial lipoproteins |
| T2 | 68-87 | protein_family_or_group | denotes | toll-like receptors |
| T3 | 143-163 | mono_cell | denotes | infectious pathogens |
| T4 | 191-205 | protein_molecule | denotes | interleukin-12 |
| T5 | 207-212 | protein_molecule | denotes | IL-12 |
| T6 | 235-255 | body_part | denotes | innate immune system |
| T7 | 308-313 | protein_molecule | denotes | IL-12 |
| T8 | 328-339 | cell_type | denotes | macrophages |
| T9 | 419-441 | protein_family_or_group | denotes | microbial lipoproteins |
| T10 | 468-473 | protein_molecule | denotes | IL-12 |
| T11 | 494-505 | cell_type | denotes | macrophages |
| T12 | 541-560 | protein_family_or_group | denotes | Toll-like receptors |
| T13 | 562-566 | protein_family_or_group | denotes | TLRs |
| T14 | 601-628 | other_name | denotes | TLR-dependent transcription |
| T15 | 642-663 | protein_molecule | denotes | nitric oxide synthase |
| T16 | 686-698 | inorganic | denotes | nitric oxide |
| T17 | 711-731 | other_name | denotes | microbicidal pathway |
| T18 | 747-751 | protein_family_or_group | denotes | TLRs |
| T19 | 755-777 | protein_family_or_group | denotes | microbial lipoproteins |
| T20 | 825-845 | mono_cell | denotes | infectious pathogens |
bionlp-st-gro-2013-training
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T2 | 37-46 | Microorganism | denotes | microbial |
| T3 | 47-59 | Protein | denotes | lipoproteins |
| T4 | 68-87 | Protein | denotes | toll-like receptors |
| T5 | 107-111 | Cell | denotes | cell |
| T8 | 191-205 | Protein | denotes | interleukin-12 |
| T9 | 207-212 | Protein | denotes | IL-12 |
| T11 | 308-313 | Protein | denotes | IL-12 |
| T13 | 328-339 | Cell | denotes | macrophages |
| T14 | 419-428 | Microorganism | denotes | microbial |
| T15 | 429-441 | Protein | denotes | lipoproteins |
| T17 | 468-473 | Protein | denotes | IL-12 |
| T19 | 488-493 | Eukaryote | denotes | human |
| T20 | 494-505 | Cell | denotes | macrophages |
| T23 | 541-560 | Protein | denotes | Toll-like receptors |
| T24 | 562-566 | Protein | denotes | TLRs |
| T25 | 577-589 | Protein | denotes | lipoproteins |
| T27 | 601-604 | Protein | denotes | TLR |
| T32 | 686-698 | Chemical | denotes | nitric oxide |
| T35 | 747-751 | Protein | denotes | TLRs |
| T36 | 755-764 | Microorganism | denotes | microbial |
| T37 | 765-777 | Protein | denotes | lipoproteins |
| T29 | 642-663 | Enzyme | denotes | nitric oxide synthase |
| E1 | 24-33 | PositiveRegulation | denotes | triggered |
| E2 | 112-120 | RegulatoryProcess | denotes | mediated |
| E3 | 177-187 | ProteinBiosynthesis | denotes | production |
| E4 | 301-307 | Increase | denotes | induce |
| E5 | 314-324 | ProteinBiosynthesis | denotes | production |
| E6 | 474-484 | ProteinBiosynthesis | denotes | production |
| E7 | 516-525 | Increase | denotes | induction |
| E8 | 529-537 | RegulatoryProcess | denotes | mediated |
| E9 | 590-600 | Increase | denotes | stimulated |
| E10 | 615-628 | Transcription | denotes | transcription |
| E11 | 672-682 | Producing | denotes | production |
| E12 | 733-743 | PositiveRegulation | denotes | Activation |
| E13 | 782-790 | PositiveRegulation | denotes | initiate |
| E14 | 791-816 | ResponseProcess | denotes | innate defense mechanisms |
| E15 | 0-23 | ResponseProcess | denotes | Host defense mechanisms |
| E16 | 121-129 | CellularProcess | denotes | immunity |
| E17 | 453-464 | Increase | denotes | stimulators |
| E18 | 711-731 | Pathway | denotes | microbicidal pathway |
| E19 | 590-600 | Increase | denotes | stimulated |
| R1 | T3 | T2 | locatedIn | lipoproteins,microbial |
| R3 | T15 | T14 | locatedIn | lipoproteins,microbial |
| R4 | T20 | T19 | fromSpecies | macrophages,human |
| R5 | T37 | T36 | locatedIn | lipoproteins,microbial |
| R7 | T3 | E1 | hasAgent | lipoproteins,triggered |
| R8 | E15 | E1 | hasPatient | Host defense mechanisms,triggered |
| R10 | T5 | E2 | hasAgent | cell,mediated |
| R11 | E16 | E2 | hasPatient | immunity,mediated |
| R12 | T8 | E3 | hasPatient | interleukin-12,production |
| R13 | E5 | E4 | hasPatient | production,induce |
| R14 | T13 | E5 | hasAgent | macrophages,production |
| R15 | T11 | E5 | hasPatient | IL-12,production |
| R16 | T20 | E6 | hasAgent | macrophages,production |
| R17 | T17 | E6 | hasPatient | IL-12,production |
| R18 | T23 | E8 | hasAgent | Toll-like receptors,mediated |
| R19 | E7 | E8 | hasPatient | induction,mediated |
| R20 | T25 | E9 | hasAgent | lipoproteins,stimulated |
| R21 | E10 | E9 | hasPatient | transcription,stimulated |
| R22 | T29 | E10 | hasPatient | nitric oxide synthase,transcription |
| R23 | T32 | E11 | hasPatient | nitric oxide,production |
| R24 | T37 | E12 | hasAgent | lipoproteins,Activation |
| R25 | T35 | E12 | hasPatient | TLRs,Activation |
| R26 | E12 | E13 | hasAgent | Activation,initiate |
| R27 | E14 | E13 | hasPatient | innate defense mechanisms,initiate |
| R28 | T15 | E17 | hasAgent | lipoproteins,stimulators |
| R29 | E6 | E17 | hasPatient | production,stimulators |
| R30 | T25 | E19 | hasAgent | lipoproteins,stimulated |
| R31 | E11 | E19 | hasPatient | production,stimulated |