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PubMed:10202178 JSONTXT

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jnlpba-st-training

Id Subject Object Predicate Lexical cue
T1 26-63 protein denotes interferon (IFN)-inducible protein 10
T2 95-103 cell_type denotes monocyte
T3 105-120 cell_type denotes macrophage cell
T4 158-174 protein denotes nuclear proteins
T5 184-213 DNA denotes IFN stimulus response element
T6 218-230 DNA denotes kappaB sites
T7 244-253 protein denotes chemokine
T8 305-313 cell_type denotes monocyte
T9 315-338 cell_line denotes macrophage cell lineage
T10 344-371 cell_line denotes human monoblastic cell line
T11 373-377 cell_line denotes U937
T12 400-411 cell_type denotes macrophages
T13 546-583 protein denotes interferon (IFN)-inducible protein 10
T14 585-590 protein denotes IP-10
T15 595-608 protein denotes CXC chemokine
T16 640-648 protein denotes IFNgamma
T17 688-698 cell_line denotes U937 cells
T18 743-762 cell_line denotes VitD3-treated cells
T19 814-844 protein denotes monocyte chemotactic protein-1
T20 848-860 protein denotes CC chemokine
T21 888-910 protein denotes transcriptional factor
T22 912-921 protein denotes FcRFgamma
T23 936-957 DNA denotes gamma response region
T24 1003-1011 protein denotes IFNgamma
T25 1051-1061 cell_line denotes U937 cells
T26 1089-1099 RNA denotes IP-10 mRNA
T27 1190-1198 protein denotes IFNgamma
T28 1224-1232 protein denotes IFNgamma
T29 1241-1251 RNA denotes IP-10 mRNA
T30 1285-1295 cell_line denotes U937 cells
T31 1445-1481 DNA denotes IFN stimulus response element (ISRE)
T32 1486-1494 DNA denotes kB sites
T33 1518-1534 protein denotes nuclear proteins
T34 1553-1563 RNA denotes IP-10 mRNA
T35 1580-1588 protein denotes IFNgamma

pubmed-sentences-benchmark

Id Subject Object Predicate Lexical cue
S1 0-231 Sentence denotes Differential induction of interferon (IFN)-inducible protein 10 following differentiation of a monocyte, macrophage cell lineage is related to the changes of nuclear proteins bound to IFN stimulus response element and kappaB sites.
S2 232-339 Sentence denotes We examined chemokine gene expression following the differentiation of a monocyte, macrophage cell lineage.
S3 340-522 Sentence denotes The human monoblastic cell line, U937 was differentiated to macrophages by the treatment with either phorbol 12-myristate 13-acetate (PMA), retinoic acid (RA), or vitamin D3 (VitD3).
S4 523-763 Sentence denotes The gene expression of interferon (IFN)-inducible protein 10 (IP-10) (a CXC chemokine) was markedly augmented by the IFNgamma treatment in PMA- or RA-differentiated U937 cells, but only marginally in undifferentiated or VitD3-treated cells.
S5 764-1199 Sentence denotes In contrast, another inducible gene expression of monocyte chemotactic protein-1 (a CC chemokine) and the activation of the transcriptional factor (FcRFgamma) bound to the gamma response region were similarly or less abundantly induced by IFNgamma treatment in PMA- or RA-differentiated U937 cells, indicating that increased IP-10 mRNA induction was not due to the augmented ability of the cells to respond to the presence of IFNgamma.
S6 1200-1589 Sentence denotes Increased expression of IFNgamma-induced IP-10 mRNA following the differentiation of U937 cells was mediated largely by augmented transcriptional activity of the gene and was related to differentiation-dependent changes of the proteins bound to IFN stimulus response element (ISRE) and kB sites, suggesting that these nuclear proteins may determine the IP-10 mRNA inducibility by IFNgamma.

genia-medco-coref

Id Subject Object Predicate Lexical cue
C1 74-128 NP denotes differentiation of a monocyte, macrophage cell lineage
C2 184-230 NP denotes IFN stimulus response element and kappaB sites
C3 280-338 NP denotes the differentiation of a monocyte, macrophage cell lineage
C4 340-371 NP denotes The human monoblastic cell line
C5 373-377 NP denotes U937
C6 636-698 NP denotes the IFNgamma treatment in PMA- or RA-differentiated U937 cells
C7 1003-1061 NP denotes IFNgamma treatment in PMA- or RA-differentiated U937 cells
C8 1190-1198 NP denotes IFNgamma
C9 1285-1295 NP denotes U937 cells
C10 1445-1494 NP denotes IFN stimulus response element (ISRE) and kB sites
C11 1580-1588 NP denotes IFNgamma
R1 C3 C1 coref-ident "the differentiation of a monocyte, macrophage cell lineage","differentiation of a monocyte, macrophage cell lineage"
R2 C5 C4 coref-appos U937,The human monoblastic cell line
R3 C7 C6 coref-ident IFNgamma treatment in PMA- or RA-differentiated U937 cells,the IFNgamma treatment in PMA- or RA-differentiated U937 cells
R4 C9 C4 coref-ident U937 cells,The human monoblastic cell line
R5 C10 C2 coref-ident IFN stimulus response element (ISRE) and kB sites,IFN stimulus response element and kappaB sites
R6 C11 C8 coref-ident IFNgamma,IFNgamma

GENIAcorpus

Id Subject Object Predicate Lexical cue
T1 0-22 other_name denotes Differential induction
T2 26-63 protein_molecule denotes interferon (IFN)-inducible protein 10
T3 95-103 cell_type denotes monocyte
T4 105-120 cell_type denotes macrophage cell
T5 158-174 protein_family_or_group denotes nuclear proteins
T6 184-213 DNA_domain_or_region denotes IFN stimulus response element
T7 218-224 DNA_molecule denotes kappaB
T8 244-253 protein_family_or_group denotes chemokine
T9 305-313 cell_type denotes monocyte
T10 315-325 cell_type denotes macrophage
T11 344-371 cell_line denotes human monoblastic cell line
T12 373-377 cell_line denotes U937
T13 400-411 cell_type denotes macrophages
T14 441-472 other_organic_compound denotes phorbol 12-myristate 13-acetate
T15 474-477 other_organic_compound denotes PMA
T16 480-493 other_organic_compound denotes retinoic acid
T17 495-497 other_organic_compound denotes RA
T18 503-515 lipid denotes vitamin D3 (
T19 515-520 lipid denotes VitD3
T20 546-583 protein_molecule denotes interferon (IFN)-inducible protein 10
T21 585-590 protein_molecule denotes IP-10
T22 595-608 protein_family_or_group denotes CXC chemokine
T23 640-648 protein_molecule denotes IFNgamma
T24 662-665 other_organic_compound denotes PMA
T25 670-672 other_organic_compound denotes RA
T26 688-698 cell_line denotes U937 cells
T27 743-748 lipid denotes VitD3
T28 814-844 protein_molecule denotes monocyte chemotactic protein-1
T29 848-860 protein_family_or_group denotes CC chemokine
T30 888-910 protein_family_or_group denotes transcriptional factor
T31 912-921 protein_molecule denotes FcRFgamma
T32 936-957 DNA_domain_or_region denotes gamma response region
T33 1003-1011 protein_molecule denotes IFNgamma
T34 1025-1028 other_organic_compound denotes PMA
T35 1033-1035 other_organic_compound denotes RA
T36 1051-1061 cell_line denotes U937 cells
T37 1089-1094 protein_molecule denotes IP-10
T38 1190-1198 protein_molecule denotes IFNgamma
T39 1224-1232 protein_molecule denotes IFNgamma
T40 1241-1246 protein_molecule denotes IP-10
T41 1285-1295 cell_line denotes U937 cells
T42 1445-1476 DNA_domain_or_region denotes IFN stimulus response element (
T43 1476-1480 DNA_domain_or_region denotes ISRE
T44 1486-1494 DNA_domain_or_region denotes kB sites
T45 1518-1534 protein_family_or_group denotes nuclear proteins
T46 1553-1558 protein_molecule denotes IP-10
T47 1580-1588 protein_molecule denotes IFNgamma