| Id |
Subject |
Object |
Predicate |
Lexical cue |
| T292 |
0-96 |
Sentence |
denotes |
The spike proteins of corona viruses are essential for entry of the virus into the target cells. |
| T293 |
97-265 |
Sentence |
denotes |
The spike protein exists as a trimer on the surface of the virus with one of the monomer in up conformation and the other two in down conformation (Wrapp et al., 2020). |
| T294 |
266-407 |
Sentence |
denotes |
The N-terminal region (S1) of the S protein is important for binding to the cellular receptor ACE2 (Hoffmann et al., 2020; Tai et al., 2020). |
| T295 |
408-584 |
Sentence |
denotes |
The S protein undergoes priming by cellular protease, TMPRSS2 and the S2 region of the protein is responsible for fusion of viral and cellular membrane (Hoffmann et al., 2020). |
| T296 |
585-744 |
Sentence |
denotes |
Therefore, identifying therapeutics for the S protein of the novel corona virus could potentially target the critical process of entry and fusion of the virus. |
