PMC:7652766 / 89740-90398 JSON TXT

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Id	Subject	Object	Predicate	Lexical cue
T438	0-217	Sentence	denotes	Deng et al. (312) have studied the association of lopinavir/ritonavir with arbidol treatment and demonstrated a significant improvement in COVID-19 patients compared with a group treated only with lopinavir/ritonavir.
T439	218-352	Sentence	denotes	Arbidol (umifenovir) is a broad-spectrum antiviral and immunomodulatory compound used to treat influenza and many other viruses (314).
T440	353-658	Sentence	denotes	Analyses of molecular dynamics and structure-guided drug-binding have suggested an efficiency of arbidol at blocking or hampering the trimerization of the SARS-CoV-2 spike glycoprotein, in addition to inhibiting virus-cell interactions, which supports the potential use of arbidol to treat COVID-19 (315).

Id	Subject	Object	Predicate	Lexical cue	tao:has_database_id
3268	634-636	Gene	denotes	to	Gene:6999
3269	551-553	Gene	denotes	to	Gene:6999
3270	304-306	Gene	denotes	to	Gene:6999
3271	148-156	Species	denotes	patients	Tax:9606
3272	508-518	Species	denotes	SARS-CoV-2	Tax:2697049
3273	313-322	Species	denotes	influenza	Tax:11309
3274	242-243	Gene	denotes	a	Gene:351
3275	171-172	Gene	denotes	a	Gene:351
3276	110-111	Gene	denotes	a	Gene:351
3277	50-69	Chemical	denotes	lopinavir/ritonavir	MESH:C558899
3278	75-82	Chemical	denotes	arbidol	MESH:C086979
3279	197-216	Chemical	denotes	lopinavir/ritonavir	MESH:C558899
3280	218-225	Chemical	denotes	Arbidol	MESH:C086979
3281	227-237	Chemical	denotes	umifenovir	MESH:C086979
3282	450-457	Chemical	denotes	arbidol	MESH:C086979
3283	626-633	Chemical	denotes	arbidol	MESH:C086979
3284	139-147	Disease	denotes	COVID-19	MESH:C000657245
3285	643-651	Disease	denotes	COVID-19	MESH:C000657245