PMC:7601109 / 68262-69418 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7601109","sourcedb":"PMC","sourceid":"7601109","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7601109","text":"Lactic acid bacteria profusely exist in bee saliva and all bee products [36,83,84]. Various species of lactic acid bacteria have been experimentally used to correct GI dysbiosis and related muscle wasting [159,160]. Moreover, oligosaccharides have been chemically isolated from bee products [32,161]. These api-materials are classified as prebiotics, fermented non-digestible compounds that promote the proliferative activity of health-promoting bacteria [24,161]. Supplementing frail old adults with fructooligosaccharides expressed positive effects on skeletal muscle strength (handgrip) and endurance (exhaustion) [162]. On the other side, microbiome of the gut can affect the biological activity of bee products. The literature shows that certain endobacteria transform dietary polyphenols into phenolic acids, which can easily access the circulation and then cross the blood brain barrier to produce therapeutic effects [163]. Hence, it is important that future investigations of bee products among sarcopenic subjects examine the effect of these products on the composition of GI microbial population and its association with muscle-related 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