PMC:7600245 / 39638-41454 JSONTXT

Annnotations TAB JSON ListView MergeView

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7600245","sourcedb":"PMC","sourceid":"7600245","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7600245","text":"Considering the current viral pandemic, CRM1 has been put forward as a facilitator of the export of viral proteins from the nucleus of the host cell to the cytoplasm as well as an amplifier of the activities of pro-inflammatory transcription factors. Thus, the CRM1 inhibitor selinexor may exert relevant antiviral and anti-inflammatory effects [122,123]. In fact, CRM1 inhibitors have exhibited activity against \u003e20 different viruses, including RNA viruses such as respiratory syncytial virus and influenza virus [122,123]. Furthermore, CRM1 inhibition has also been identified in in vitro assays to have a potential activity against SARS-CoV-2 [124]. CRM1 was found to contribute to exporting several SARS-CoV proteins, such as S, N, 9b, Orf3 and Orf6 out of the nucleus. Thus, CRM1 inhibition is expected to inhibit the viral assembly [125,126,127,128,129]. Moreover, CRM1 has also been found to contribute to the nuclear export and functional inactivation of antioxidant, anti-inflammatory, and cytoprotective transcription factors [130]. High levels of CRM1 are found in multiple inflammatory conditions and may magnify inflammatory responses leading to severe organ damage [131]. In this direction, selinexor and similar inhibitors have exhibited potent anti-inflammatory activity by suppressing the activation of NFkB and p38 signaling, leading to reduced cytokines in a variety of models. For example, in a mouse model of sepsis, selinexor increased survival following a lethal dose of endotoxin. Selinexor reduced the inflammatory cytokine secretion of IL-6, TNF-α, and HMGB1 while reducing the numbers of macrophage and polymorphonuclear neutrophils in the mice peritoneal cavity. Selinexor also mitigated lipopolysaccharide-induced lung injury that is similar to acute respiratory distress syndrome [132].","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T164","span":{"begin":106,"end":114},"obj":"Body_part"},{"id":"T165","span":{"begin":144,"end":148},"obj":"Body_part"},{"id":"T166","span":{"begin":156,"end":165},"obj":"Body_part"},{"id":"T167","span":{"begin":446,"end":449},"obj":"Body_part"},{"id":"T168","span":{"begin":712,"end":720},"obj":"Body_part"},{"id":"T169","span":{"begin":1166,"end":1171},"obj":"Body_part"},{"id":"T170","span":{"begin":1363,"end":1372},"obj":"Body_part"},{"id":"T171","span":{"begin":1540,"end":1548},"obj":"Body_part"},{"id":"T172","span":{"begin":1615,"end":1625},"obj":"Body_part"},{"id":"T173","span":{"begin":1648,"end":1659},"obj":"Body_part"},{"id":"T174","span":{"begin":1672,"end":1689},"obj":"Body_part"},{"id":"T175","span":{"begin":1716,"end":1734},"obj":"Body_part"},{"id":"T176","span":{"begin":1743,"end":1747},"obj":"Body_part"}],"attributes":[{"id":"A164","pred":"fma_id","subj":"T164","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A165","pred":"fma_id","subj":"T165","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A166","pred":"fma_id","subj":"T166","obj":"http://purl.org/sig/ont/fma/fma66835"},{"id":"A167","pred":"fma_id","subj":"T167","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A168","pred":"fma_id","subj":"T168","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A169","pred":"fma_id","subj":"T169","obj":"http://purl.org/sig/ont/fma/fma67498"},{"id":"A170","pred":"fma_id","subj":"T170","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A171","pred":"fma_id","subj":"T171","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A172","pred":"fma_id","subj":"T172","obj":"http://purl.org/sig/ont/fma/fma63261"},{"id":"A173","pred":"fma_id","subj":"T173","obj":"http://purl.org/sig/ont/fma/fma62860"},{"id":"A174","pred":"fma_id","subj":"T174","obj":"http://purl.org/sig/ont/fma/fma14704"},{"id":"A175","pred":"fma_id","subj":"T175","obj":"http://purl.org/sig/ont/fma/fma82785"},{"id":"A176","pred":"fma_id","subj":"T176","obj":"http://purl.org/sig/ont/fma/fma7195"},{"subj":"T164","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T165","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T166","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T167","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T168","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T169","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T170","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T171","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T172","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T173","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T174","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T175","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T176","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T6","span":{"begin":1166,"end":1171},"obj":"Body_part"},{"id":"T7","span":{"begin":1672,"end":1689},"obj":"Body_part"},{"id":"T8","span":{"begin":1743,"end":1747},"obj":"Body_part"}],"attributes":[{"id":"A6","pred":"uberon_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"},{"id":"A7","pred":"uberon_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/UBERON_0001179"},{"id":"A8","pred":"uberon_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"subj":"T6","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T149","span":{"begin":498,"end":507},"obj":"Disease"},{"id":"T150","span":{"begin":635,"end":643},"obj":"Disease"},{"id":"T151","span":{"begin":703,"end":711},"obj":"Disease"},{"id":"T152","span":{"begin":1748,"end":1754},"obj":"Disease"},{"id":"T153","span":{"begin":1774,"end":1809},"obj":"Disease"},{"id":"T154","span":{"begin":1780,"end":1809},"obj":"Disease"}],"attributes":[{"id":"A149","pred":"mondo_id","subj":"T149","obj":"http://purl.obolibrary.org/obo/MONDO_0005812"},{"id":"A150","pred":"mondo_id","subj":"T150","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A151","pred":"mondo_id","subj":"T151","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"},{"id":"A152","pred":"mondo_id","subj":"T152","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A153","pred":"mondo_id","subj":"T153","obj":"http://purl.obolibrary.org/obo/MONDO_0006502"},{"id":"A154","pred":"mondo_id","subj":"T154","obj":"http://purl.obolibrary.org/obo/MONDO_0009971"},{"subj":"T149","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T150","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T151","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T152","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T153","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T154","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T355","span":{"begin":45,"end":48},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T356","span":{"begin":69,"end":70},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T357","span":{"begin":144,"end":148},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T358","span":{"begin":197,"end":207},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T359","span":{"begin":396,"end":404},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T360","span":{"begin":427,"end":434},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T361","span":{"begin":450,"end":457},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T362","span":{"begin":488,"end":493},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T363","span":{"begin":508,"end":513},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T364","span":{"begin":554,"end":557},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T365","span":{"begin":606,"end":607},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T366","span":{"begin":618,"end":626},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T367","span":{"begin":876,"end":879},"obj":"http://purl.obolibrary.org/obo/CLO_0051582"},{"id":"T368","span":{"begin":1166,"end":1171},"obj":"http://purl.obolibrary.org/obo/UBERON_0003103"},{"id":"T369","span":{"begin":1278,"end":1286},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T370","span":{"begin":1306,"end":1316},"obj":"http://purl.obolibrary.org/obo/CLO_0001658"},{"id":"T371","span":{"begin":1333,"end":1342},"obj":"http://purl.obolibrary.org/obo/SO_0000418"},{"id":"T372","span":{"begin":1376,"end":1377},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T373","span":{"begin":1413,"end":1414},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T374","span":{"begin":1415,"end":1420},"obj":"http://purl.obolibrary.org/obo/CLO_0007836"},{"id":"T375","span":{"begin":1477,"end":1478},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T376","span":{"begin":1672,"end":1689},"obj":"http://purl.obolibrary.org/obo/UBERON_0001179"},{"id":"T377","span":{"begin":1743,"end":1747},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T378","span":{"begin":1743,"end":1747},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T379","span":{"begin":1811,"end":1814},"obj":"http://purl.obolibrary.org/obo/CLO_0054061"}],"attributes":[{"subj":"T355","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T356","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T357","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T358","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T359","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T360","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T361","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T362","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T363","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T364","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T365","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T366","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T367","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T368","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T369","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T370","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T371","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T372","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T373","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T374","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T375","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T376","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T377","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T378","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T379","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T597","span":{"begin":106,"end":114},"obj":"Chemical"},{"id":"T598","span":{"begin":124,"end":131},"obj":"Chemical"},{"id":"T599","span":{"begin":266,"end":275},"obj":"Chemical"},{"id":"T600","span":{"begin":305,"end":314},"obj":"Chemical"},{"id":"T601","span":{"begin":370,"end":380},"obj":"Chemical"},{"id":"T602","span":{"begin":712,"end":720},"obj":"Chemical"},{"id":"T603","span":{"begin":765,"end":772},"obj":"Chemical"},{"id":"T604","span":{"begin":963,"end":974},"obj":"Chemical"},{"id":"T605","span":{"begin":1227,"end":1237},"obj":"Chemical"},{"id":"T606","span":{"begin":1562,"end":1564},"obj":"Chemical"},{"id":"T608","span":{"begin":1716,"end":1734},"obj":"Chemical"}],"attributes":[{"id":"A597","pred":"chebi_id","subj":"T597","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A598","pred":"chebi_id","subj":"T598","obj":"http://purl.obolibrary.org/obo/CHEBI_33252"},{"id":"A599","pred":"chebi_id","subj":"T599","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A600","pred":"chebi_id","subj":"T600","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A601","pred":"chebi_id","subj":"T601","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A602","pred":"chebi_id","subj":"T602","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A603","pred":"chebi_id","subj":"T603","obj":"http://purl.obolibrary.org/obo/CHEBI_33252"},{"id":"A604","pred":"chebi_id","subj":"T604","obj":"http://purl.obolibrary.org/obo/CHEBI_22586"},{"id":"A605","pred":"chebi_id","subj":"T605","obj":"http://purl.obolibrary.org/obo/CHEBI_35222"},{"id":"A606","pred":"chebi_id","subj":"T606","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A607","pred":"chebi_id","subj":"T606","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A608","pred":"chebi_id","subj":"T608","obj":"http://purl.obolibrary.org/obo/CHEBI_16412"},{"subj":"T597","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T598","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T599","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T600","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T601","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T602","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T603","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T604","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T605","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T606","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T608","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T58","span":{"begin":228,"end":249},"obj":"http://purl.obolibrary.org/obo/GO_0000981"},{"id":"T59","span":{"begin":228,"end":241},"obj":"http://purl.obolibrary.org/obo/GO_0006351"},{"id":"T60","span":{"begin":823,"end":837},"obj":"http://purl.obolibrary.org/obo/GO_0019068"},{"id":"T61","span":{"begin":917,"end":931},"obj":"http://purl.obolibrary.org/obo/GO_0051168"},{"id":"T62","span":{"begin":1014,"end":1035},"obj":"http://purl.obolibrary.org/obo/GO_0000981"},{"id":"T63","span":{"begin":1014,"end":1027},"obj":"http://purl.obolibrary.org/obo/GO_0006351"},{"id":"T64","span":{"begin":1125,"end":1147},"obj":"http://purl.obolibrary.org/obo/GO_0006954"},{"id":"T65","span":{"begin":1333,"end":1342},"obj":"http://purl.obolibrary.org/obo/GO_0023052"},{"id":"T66","span":{"begin":1540,"end":1558},"obj":"http://purl.obolibrary.org/obo/GO_0001816"},{"id":"T67","span":{"begin":1549,"end":1558},"obj":"http://purl.obolibrary.org/obo/GO_0046903"}],"attributes":[{"subj":"T58","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T59","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T60","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T61","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T62","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T63","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T64","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T65","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T66","pred":"source","obj":"LitCovid-PD-GO-BP"},{"subj":"T67","pred":"source","obj":"LitCovid-PD-GO-BP"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T25","span":{"begin":1430,"end":1436},"obj":"Phenotype"},{"id":"T26","span":{"begin":1780,"end":1800},"obj":"Phenotype"}],"attributes":[{"id":"A25","pred":"hp_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/HP_0100806"},{"id":"A26","pred":"hp_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/HP_0002098"},{"subj":"T25","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T26","pred":"source","obj":"LitCovid-PD-HP"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T299","span":{"begin":0,"end":250},"obj":"Sentence"},{"id":"T300","span":{"begin":251,"end":355},"obj":"Sentence"},{"id":"T301","span":{"begin":356,"end":524},"obj":"Sentence"},{"id":"T302","span":{"begin":525,"end":652},"obj":"Sentence"},{"id":"T303","span":{"begin":653,"end":773},"obj":"Sentence"},{"id":"T304","span":{"begin":774,"end":860},"obj":"Sentence"},{"id":"T305","span":{"begin":861,"end":1042},"obj":"Sentence"},{"id":"T306","span":{"begin":1043,"end":1185},"obj":"Sentence"},{"id":"T307","span":{"begin":1186,"end":1396},"obj":"Sentence"},{"id":"T308","span":{"begin":1397,"end":1504},"obj":"Sentence"},{"id":"T309","span":{"begin":1505,"end":1690},"obj":"Sentence"},{"id":"T310","span":{"begin":1691,"end":1816},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T299","pred":"source","obj":"LitCovid-sentences"},{"subj":"T300","pred":"source","obj":"LitCovid-sentences"},{"subj":"T301","pred":"source","obj":"LitCovid-sentences"},{"subj":"T302","pred":"source","obj":"LitCovid-sentences"},{"subj":"T303","pred":"source","obj":"LitCovid-sentences"},{"subj":"T304","pred":"source","obj":"LitCovid-sentences"},{"subj":"T305","pred":"source","obj":"LitCovid-sentences"},{"subj":"T306","pred":"source","obj":"LitCovid-sentences"},{"subj":"T307","pred":"source","obj":"LitCovid-sentences"},{"subj":"T308","pred":"source","obj":"LitCovid-sentences"},{"subj":"T309","pred":"source","obj":"LitCovid-sentences"},{"subj":"T310","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"1213","span":{"begin":40,"end":44},"obj":"Gene"},{"id":"1214","span":{"begin":261,"end":265},"obj":"Gene"},{"id":"1215","span":{"begin":365,"end":369},"obj":"Gene"},{"id":"1216","span":{"begin":538,"end":542},"obj":"Gene"},{"id":"1217","span":{"begin":653,"end":657},"obj":"Gene"},{"id":"1218","span":{"begin":740,"end":744},"obj":"Gene"},{"id":"1219","span":{"begin":780,"end":784},"obj":"Gene"},{"id":"1220","span":{"begin":871,"end":875},"obj":"Gene"},{"id":"1221","span":{"begin":1058,"end":1062},"obj":"Gene"},{"id":"1222","span":{"begin":1329,"end":1332},"obj":"Gene"},{"id":"1223","span":{"begin":1562,"end":1566},"obj":"Gene"},{"id":"1224","span":{"begin":1568,"end":1573},"obj":"Gene"},{"id":"1225","span":{"begin":1579,"end":1584},"obj":"Gene"},{"id":"1226","span":{"begin":466,"end":493},"obj":"Species"},{"id":"1227","span":{"begin":498,"end":513},"obj":"Species"},{"id":"1228","span":{"begin":635,"end":645},"obj":"Species"},{"id":"1229","span":{"begin":703,"end":711},"obj":"Species"},{"id":"1230","span":{"begin":1415,"end":1420},"obj":"Species"},{"id":"1231","span":{"begin":1667,"end":1671},"obj":"Species"},{"id":"1232","span":{"begin":276,"end":285},"obj":"Chemical"},{"id":"1233","span":{"begin":1205,"end":1214},"obj":"Chemical"},{"id":"1234","span":{"begin":1438,"end":1447},"obj":"Chemical"},{"id":"1235","span":{"begin":1691,"end":1700},"obj":"Chemical"},{"id":"1236","span":{"begin":1716,"end":1734},"obj":"Chemical"},{"id":"1237","span":{"begin":1430,"end":1436},"obj":"Disease"},{"id":"1238","span":{"begin":1743,"end":1754},"obj":"Disease"},{"id":"1239","span":{"begin":1774,"end":1809},"obj":"Disease"}],"attributes":[{"id":"A1213","pred":"tao:has_database_id","subj":"1213","obj":"Gene:7514"},{"id":"A1214","pred":"tao:has_database_id","subj":"1214","obj":"Gene:7514"},{"id":"A1215","pred":"tao:has_database_id","subj":"1215","obj":"Gene:7514"},{"id":"A1216","pred":"tao:has_database_id","subj":"1216","obj":"Gene:7514"},{"id":"A1217","pred":"tao:has_database_id","subj":"1217","obj":"Gene:7514"},{"id":"A1218","pred":"tao:has_database_id","subj":"1218","obj":"Gene:136991"},{"id":"A1219","pred":"tao:has_database_id","subj":"1219","obj":"Gene:7514"},{"id":"A1220","pred":"tao:has_database_id","subj":"1220","obj":"Gene:7514"},{"id":"A1221","pred":"tao:has_database_id","subj":"1221","obj":"Gene:7514"},{"id":"A1222","pred":"tao:has_database_id","subj":"1222","obj":"Gene:1432"},{"id":"A1223","pred":"tao:has_database_id","subj":"1223","obj":"Gene:16193"},{"id":"A1224","pred":"tao:has_database_id","subj":"1224","obj":"Gene:21926"},{"id":"A1225","pred":"tao:has_database_id","subj":"1225","obj":"Gene:15289"},{"id":"A1226","pred":"tao:has_database_id","subj":"1226","obj":"Tax:12814"},{"id":"A1227","pred":"tao:has_database_id","subj":"1227","obj":"Tax:11308"},{"id":"A1228","pred":"tao:has_database_id","subj":"1228","obj":"Tax:2697049"},{"id":"A1229","pred":"tao:has_database_id","subj":"1229","obj":"Tax:694009"},{"id":"A1230","pred":"tao:has_database_id","subj":"1230","obj":"Tax:10090"},{"id":"A1231","pred":"tao:has_database_id","subj":"1231","obj":"Tax:10090"},{"id":"A1232","pred":"tao:has_database_id","subj":"1232","obj":"MESH:C585161"},{"id":"A1233","pred":"tao:has_database_id","subj":"1233","obj":"MESH:C585161"},{"id":"A1234","pred":"tao:has_database_id","subj":"1234","obj":"MESH:C585161"},{"id":"A1235","pred":"tao:has_database_id","subj":"1235","obj":"MESH:C585161"},{"id":"A1236","pred":"tao:has_database_id","subj":"1236","obj":"MESH:D008070"},{"id":"A1237","pred":"tao:has_database_id","subj":"1237","obj":"MESH:D018805"},{"id":"A1238","pred":"tao:has_database_id","subj":"1238","obj":"MESH:D055370"},{"id":"A1239","pred":"tao:has_database_id","subj":"1239","obj":"MESH:D012128"},{"subj":"1213","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1214","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1215","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1216","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1217","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1218","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1219","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1220","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1221","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1222","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1223","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1224","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1225","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1226","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1227","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1228","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1229","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1230","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1231","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1232","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1233","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1234","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1235","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1236","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1237","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1238","pred":"source","obj":"LitCovid-PubTator"},{"subj":"1239","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#ec9593","default":true},{"id":"LitCovid-PD-UBERON","color":"#93aaec"},{"id":"LitCovid-PD-MONDO","color":"#c4ec93"},{"id":"LitCovid-PD-CLO","color":"#ec93de"},{"id":"LitCovid-PD-CHEBI","color":"#93ecdf"},{"id":"LitCovid-PD-GO-BP","color":"#ecc593"},{"id":"LitCovid-PD-HP","color":"#ab93ec"},{"id":"LitCovid-sentences","color":"#94ec93"},{"id":"LitCovid-PubTator","color":"#ec93ae"}]}]}}