PMC:7558914 / 32496-33533 JSONTXT

{"project":"LitCovid-sentences","denotations":[{"id":"T229","span":{"begin":0,"end":15},"obj":"Sentence"},{"id":"T230","span":{"begin":16,"end":29},"obj":"Sentence"},{"id":"T231","span":{"begin":30,"end":70},"obj":"Sentence"},{"id":"T232","span":{"begin":71,"end":111},"obj":"Sentence"},{"id":"T233","span":{"begin":112,"end":130},"obj":"Sentence"},{"id":"T234","span":{"begin":131,"end":177},"obj":"Sentence"},{"id":"T235","span":{"begin":178,"end":221},"obj":"Sentence"},{"id":"T236","span":{"begin":222,"end":261},"obj":"Sentence"},{"id":"T237","span":{"begin":262,"end":301},"obj":"Sentence"},{"id":"T238","span":{"begin":302,"end":313},"obj":"Sentence"},{"id":"T239","span":{"begin":314,"end":436},"obj":"Sentence"},{"id":"T240","span":{"begin":437,"end":560},"obj":"Sentence"},{"id":"T241","span":{"begin":561,"end":569},"obj":"Sentence"},{"id":"T242","span":{"begin":570,"end":609},"obj":"Sentence"},{"id":"T243","span":{"begin":610,"end":649},"obj":"Sentence"},{"id":"T244","span":{"begin":650,"end":748},"obj":"Sentence"},{"id":"T245","span":{"begin":749,"end":817},"obj":"Sentence"},{"id":"T246","span":{"begin":818,"end":912},"obj":"Sentence"},{"id":"T247","span":{"begin":913,"end":987},"obj":"Sentence"},{"id":"T248","span":{"begin":988,"end":1003},"obj":"Sentence"},{"id":"T249","span":{"begin":1004,"end":1037},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Corticosteroids\nDexamethasone\nRegimen 1 20 mg every 24 h for 3–5 days\nRegimen 2 40 mg every 24 h for 3–5 days\nMethylprednisolone\nRegimen 1 125–250 mg every 24 h for 3–10 days\nRegimen 2 1 mg/kg every 24 h for 3–10 days\nPrednisone 40 mg every 24 h for 5 days\nAnticytokine or immunomodulatory agents\nTocilizumab\nRegimen 1 (Body weight \u003c75 kg) Single dose of 400 mgSecond dose of 400 mg could be administered 12–24 h later if required\nRegimen 2 (Body weight ≥75 kg) Single dose of 600 mg.Second dose of 400 mg could be administered 12–24 h later if required\nAnakinra\nRegimen 1 100 mg every 24 h for 3 days\nRegimen 2 200 mg every 12 h for 3 days\nRegimen 3 100 mg every 6 h (day 1), 100 mg every 12 h (day 2)Optionally 100 mg every 12 h (day 3)\nRegimen 4 200 mg every 24 h (day 1) and 100 mg every 24 h (day 2–5)\nRegimen 5 100 mg every 6 h (day 1), 100 mg every 8 h (day 2), and 100 mg every 12 h (day 3–7)\nRegimen 6 200 mg every 24 h (day 1), and 100 mg every 6-8 h for 5-10 days\nImmunoglobulins\nRegimen 400 mg/kg/day for 5 days"}