PMC:7558914 / 32496-33533
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7558914","sourcedb":"PMC","sourceid":"7558914","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7558914","text":"Corticosteroids\nDexamethasone\nRegimen 1 20 mg every 24 h for 3–5 days\nRegimen 2 40 mg every 24 h for 3–5 days\nMethylprednisolone\nRegimen 1 125–250 mg every 24 h for 3–10 days\nRegimen 2 1 mg/kg every 24 h for 3–10 days\nPrednisone 40 mg every 24 h for 5 days\nAnticytokine or immunomodulatory agents\nTocilizumab\nRegimen 1 (Body weight \u003c75 kg) Single dose of 400 mgSecond dose of 400 mg could be administered 12–24 h later if required\nRegimen 2 (Body weight ≥75 kg) Single dose of 600 mg.Second dose of 400 mg could be administered 12–24 h later if required\nAnakinra\nRegimen 1 100 mg every 24 h for 3 days\nRegimen 2 200 mg every 12 h for 3 days\nRegimen 3 100 mg every 6 h (day 1), 100 mg every 12 h (day 2)Optionally 100 mg every 12 h (day 3)\nRegimen 4 200 mg every 24 h (day 1) and 100 mg every 24 h (day 2–5)\nRegimen 5 100 mg every 6 h (day 1), 100 mg every 8 h (day 2), and 100 mg every 12 h (day 3–7)\nRegimen 6 200 mg every 24 h (day 1), and 100 mg every 6-8 h for 5-10 days\nImmunoglobulins\nRegimen 400 mg/kg/day for 5 days","divisions":[{"label":"tr","span":{"begin":0,"end":16}},{"label":"td","span":{"begin":0,"end":16}},{"label":"tr","span":{"begin":16,"end":29}},{"label":"td","span":{"begin":16,"end":30}},{"label":"tr","span":{"begin":30,"end":70}},{"label":"td","span":{"begin":30,"end":39}},{"label":"td","span":{"begin":41,"end":70}},{"label":"tr","span":{"begin":71,"end":111}},{"label":"td","span":{"begin":71,"end":80}},{"label":"td","span":{"begin":82,"end":111}},{"label":"tr","span":{"begin":112,"end":130}},{"label":"td","span":{"begin":112,"end":131}},{"label":"tr","span":{"begin":131,"end":177}},{"label":"td","span":{"begin":131,"end":140}},{"label":"td","span":{"begin":142,"end":177}},{"label":"tr","span":{"begin":178,"end":221}},{"label":"td","span":{"begin":178,"end":187}},{"label":"td","span":{"begin":189,"end":221}},{"label":"tr","span":{"begin":222,"end":261}},{"label":"td","span":{"begin":222,"end":233}},{"label":"td","span":{"begin":234,"end":261}},{"label":"tr","span":{"begin":262,"end":301}},{"label":"td","span":{"begin":262,"end":301}},{"label":"tr","span":{"begin":302,"end":313}},{"label":"td","span":{"begin":302,"end":314}},{"label":"tr","span":{"begin":314,"end":436}},{"label":"td","span":{"begin":314,"end":344}},{"label":"td","span":{"begin":346,"end":436}},{"label":"tr","span":{"begin":437,"end":560}},{"label":"td","span":{"begin":437,"end":467}},{"label":"td","span":{"begin":469,"end":560}},{"label":"tr","span":{"begin":561,"end":569}},{"label":"td","span":{"begin":561,"end":570}},{"label":"tr","span":{"begin":570,"end":609}},{"label":"td","span":{"begin":570,"end":579}},{"label":"td","span":{"begin":581,"end":609}},{"label":"tr","span":{"begin":610,"end":649}},{"label":"td","span":{"begin":610,"end":619}},{"label":"td","span":{"begin":621,"end":649}},{"label":"tr","span":{"begin":650,"end":748}},{"label":"td","span":{"begin":650,"end":659}},{"label":"td","span":{"begin":661,"end":748}},{"label":"tr","span":{"begin":749,"end":817}},{"label":"td","span":{"begin":749,"end":758}},{"label":"td","span":{"begin":760,"end":817}},{"label":"tr","span":{"begin":818,"end":912}},{"label":"td","span":{"begin":818,"end":827}},{"label":"td","span":{"begin":829,"end":912}},{"label":"tr","span":{"begin":913,"end":987}},{"label":"td","span":{"begin":913,"end":922}},{"label":"td","span":{"begin":924,"end":987}},{"label":"tr","span":{"begin":988,"end":1003}},{"label":"td","span":{"begin":988,"end":1004}},{"label":"td","span":{"begin":1004,"end":1011}}],"tracks":[{"project":"LitCovid-sentences","denotations":[{"id":"T229","span":{"begin":0,"end":15},"obj":"Sentence"},{"id":"T230","span":{"begin":16,"end":29},"obj":"Sentence"},{"id":"T231","span":{"begin":30,"end":70},"obj":"Sentence"},{"id":"T232","span":{"begin":71,"end":111},"obj":"Sentence"},{"id":"T233","span":{"begin":112,"end":130},"obj":"Sentence"},{"id":"T234","span":{"begin":131,"end":177},"obj":"Sentence"},{"id":"T235","span":{"begin":178,"end":221},"obj":"Sentence"},{"id":"T236","span":{"begin":222,"end":261},"obj":"Sentence"},{"id":"T237","span":{"begin":262,"end":301},"obj":"Sentence"},{"id":"T238","span":{"begin":302,"end":313},"obj":"Sentence"},{"id":"T239","span":{"begin":314,"end":436},"obj":"Sentence"},{"id":"T240","span":{"begin":437,"end":560},"obj":"Sentence"},{"id":"T241","span":{"begin":561,"end":569},"obj":"Sentence"},{"id":"T242","span":{"begin":570,"end":609},"obj":"Sentence"},{"id":"T243","span":{"begin":610,"end":649},"obj":"Sentence"},{"id":"T244","span":{"begin":650,"end":748},"obj":"Sentence"},{"id":"T245","span":{"begin":749,"end":817},"obj":"Sentence"},{"id":"T246","span":{"begin":818,"end":912},"obj":"Sentence"},{"id":"T247","span":{"begin":913,"end":987},"obj":"Sentence"},{"id":"T248","span":{"begin":988,"end":1003},"obj":"Sentence"},{"id":"T249","span":{"begin":1004,"end":1037},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T229","pred":"source","obj":"LitCovid-sentences"},{"subj":"T230","pred":"source","obj":"LitCovid-sentences"},{"subj":"T231","pred":"source","obj":"LitCovid-sentences"},{"subj":"T232","pred":"source","obj":"LitCovid-sentences"},{"subj":"T233","pred":"source","obj":"LitCovid-sentences"},{"subj":"T234","pred":"source","obj":"LitCovid-sentences"},{"subj":"T235","pred":"source","obj":"LitCovid-sentences"},{"subj":"T236","pred":"source","obj":"LitCovid-sentences"},{"subj":"T237","pred":"source","obj":"LitCovid-sentences"},{"subj":"T238","pred":"source","obj":"LitCovid-sentences"},{"subj":"T239","pred":"source","obj":"LitCovid-sentences"},{"subj":"T240","pred":"source","obj":"LitCovid-sentences"},{"subj":"T241","pred":"source","obj":"LitCovid-sentences"},{"subj":"T242","pred":"source","obj":"LitCovid-sentences"},{"subj":"T243","pred":"source","obj":"LitCovid-sentences"},{"subj":"T244","pred":"source","obj":"LitCovid-sentences"},{"subj":"T245","pred":"source","obj":"LitCovid-sentences"},{"subj":"T246","pred":"source","obj":"LitCovid-sentences"},{"subj":"T247","pred":"source","obj":"LitCovid-sentences"},{"subj":"T248","pred":"source","obj":"LitCovid-sentences"},{"subj":"T249","pred":"source","obj":"LitCovid-sentences"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-sentences","color":"#afec93","default":true}]}]}}