PMC:7556165 / 63126-63571 JSONTXT

{"project":"LitCovid-sample-CHEBI","denotations":[{"id":"T175","span":{"begin":37,"end":44},"obj":"Chemical"},{"id":"T176","span":{"begin":84,"end":91},"obj":"Chemical"},{"id":"T177","span":{"begin":111,"end":118},"obj":"Chemical"},{"id":"T178","span":{"begin":159,"end":166},"obj":"Chemical"}],"attributes":[{"id":"A175","pred":"chebi_id","subj":"T175","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A176","pred":"chebi_id","subj":"T176","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A177","pred":"chebi_id","subj":"T177","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A178","pred":"chebi_id","subj":"T178","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"}],"text":"One common PRR is NOD-like receptors protein 3 (NLRP3), which forms together with a protein caspase activating protein (ASC or apoptosis-associated speck-like protein containing a caspase recruitment domain) and pro-caspase 1, the inflammasome unit capable of recruiting proinflammatory cytokines and inducing cell lysis with further inflammation signals (Fernandes-Alnemri et al., 2007; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9)."}

{"project":"LitCovid-sample-sentences","denotations":[{"id":"T378","span":{"begin":0,"end":445},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"One common PRR is NOD-like receptors protein 3 (NLRP3), which forms together with a protein caspase activating protein (ASC or apoptosis-associated speck-like protein containing a caspase recruitment domain) and pro-caspase 1, the inflammasome unit capable of recruiting proinflammatory cytokines and inducing cell lysis with further inflammation signals (Fernandes-Alnemri et al., 2007; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9)."}

{"project":"LitCovid-sample-Pubtator","denotations":[{"id":"1727","span":{"begin":48,"end":53},"obj":"Gene"},{"id":"1728","span":{"begin":216,"end":225},"obj":"Gene"},{"id":"1731","span":{"begin":334,"end":346},"obj":"Disease"}],"attributes":[{"id":"A1727","pred":"pubann:denotes","subj":"1727","obj":"Gene:114548"},{"id":"A1728","pred":"pubann:denotes","subj":"1728","obj":"Gene:834"},{"id":"A1731","pred":"pubann:denotes","subj":"1731","obj":"MESH:D007249"}],"text":"One common PRR is NOD-like receptors protein 3 (NLRP3), which forms together with a protein caspase activating protein (ASC or apoptosis-associated speck-like protein containing a caspase recruitment domain) and pro-caspase 1, the inflammasome unit capable of recruiting proinflammatory cytokines and inducing cell lysis with further inflammation signals (Fernandes-Alnemri et al., 2007; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9)."}

{"project":"LitCovid-sample-UniProt","denotations":[{"id":"T5874","span":{"begin":37,"end":46},"obj":"Protein"},{"id":"T5893","span":{"begin":82,"end":91},"obj":"Protein"},{"id":"T5902","span":{"begin":92,"end":99},"obj":"Protein"},{"id":"T5904","span":{"begin":120,"end":123},"obj":"Protein"},{"id":"T5908","span":{"begin":180,"end":187},"obj":"Protein"},{"id":"T5910","span":{"begin":216,"end":225},"obj":"Protein"}],"attributes":[{"id":"A5874","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/Q9JGT9"},{"id":"A5875","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/Q98663"},{"id":"A5876","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/Q8V3T9"},{"id":"A5877","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/Q6UBL8"},{"id":"A5878","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/Q6Q1S1"},{"id":"A5879","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/Q6E0W9"},{"id":"A5880","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/Q68Y30"},{"id":"A5881","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/Q5GA88"},{"id":"A5882","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/Q3LZX0"},{"id":"A5883","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/Q3I5J4"},{"id":"A5884","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/Q12988"},{"id":"A5885","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/Q0Q474"},{"id":"A5886","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/Q02967"},{"id":"A5887","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/Q00967"},{"id":"A5888","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/P09522"},{"id":"A5889","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/P05398"},{"id":"A5890","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/P03553"},{"id":"A5891","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/P03552"},{"id":"A5892","pred":"uniprot_id","subj":"T5874","obj":"https://www.uniprot.org/uniprot/P03551"},{"id":"A5893","pred":"uniprot_id","subj":"T5893","obj":"https://www.uniprot.org/uniprot/Q38365"},{"id":"A5894","pred":"uniprot_id","subj":"T5893","obj":"https://www.uniprot.org/uniprot/P25244"},{"id":"A5895","pred":"uniprot_id","subj":"T5893","obj":"https://www.uniprot.org/uniprot/P25243"},{"id":"A5896","pred":"uniprot_id","subj":"T5893","obj":"https://www.uniprot.org/uniprot/P15966"},{"id":"A5897","pred":"uniprot_id","subj":"T5893","obj":"https://www.uniprot.org/uniprot/P09676"},{"id":"A5898","pred":"uniprot_id","subj":"T5893","obj":"https://www.uniprot.org/uniprot/P07394"},{"id":"A5899","pred":"uniprot_id","subj":"T5893","obj":"https://www.uniprot.org/uniprot/P03632"},{"id":"A5900","pred":"uniprot_id","subj":"T5893","obj":"https://www.uniprot.org/uniprot/P03610"},{"id":"A5901","pred":"uniprot_id","subj":"T5893","obj":"https://www.uniprot.org/uniprot/O64306"},{"id":"A5902","pred":"uniprot_id","subj":"T5902","obj":"https://www.uniprot.org/uniprot/Q9VAH1"},{"id":"A5903","pred":"uniprot_id","subj":"T5902","obj":"https://www.uniprot.org/uniprot/O01382"},{"id":"A5904","pred":"uniprot_id","subj":"T5904","obj":"https://www.uniprot.org/uniprot/P50427"},{"id":"A5905","pred":"uniprot_id","subj":"T5904","obj":"https://www.uniprot.org/uniprot/P15589"},{"id":"A5906","pred":"uniprot_id","subj":"T5904","obj":"https://www.uniprot.org/uniprot/P08842"},{"id":"A5907","pred":"uniprot_id","subj":"T5904","obj":"https://www.uniprot.org/uniprot/B2RA47"},{"id":"A5908","pred":"uniprot_id","subj":"T5908","obj":"https://www.uniprot.org/uniprot/Q9VAH1"},{"id":"A5909","pred":"uniprot_id","subj":"T5908","obj":"https://www.uniprot.org/uniprot/O01382"},{"id":"A5910","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/Q9W1N0"},{"id":"A5911","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/Q9UCN3"},{"id":"A5912","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/Q9TV13"},{"id":"A5913","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/Q9N2I1"},{"id":"A5914","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/Q9MZV7"},{"id":"A5915","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/Q9MZV6"},{"id":"A5916","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/Q6PI75"},{"id":"A5917","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/Q6GSS3"},{"id":"A5918","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/Q6DMQ1"},{"id":"A5919","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/Q53EY6"},{"id":"A5920","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/P89116"},{"id":"A5921","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/P43527"},{"id":"A5922","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/P29466"},{"id":"A5923","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/P29452"},{"id":"A5924","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/O02002"},{"id":"A5925","pred":"uniprot_id","subj":"T5910","obj":"https://www.uniprot.org/uniprot/B5MDZ1"}],"text":"One common PRR is NOD-like receptors protein 3 (NLRP3), which forms together with a protein caspase activating protein (ASC or apoptosis-associated speck-like protein containing a caspase recruitment domain) and pro-caspase 1, the inflammasome unit capable of recruiting proinflammatory cytokines and inducing cell lysis with further inflammation signals (Fernandes-Alnemri et al., 2007; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9)."}

{"project":"LitCovid-sample-PD-IDO","denotations":[{"id":"T254","span":{"begin":310,"end":314},"obj":"http://purl.obolibrary.org/obo/CL_0000000"}],"text":"One common PRR is NOD-like receptors protein 3 (NLRP3), which forms together with a protein caspase activating protein (ASC or apoptosis-associated speck-like protein containing a caspase recruitment domain) and pro-caspase 1, the inflammasome unit capable of recruiting proinflammatory cytokines and inducing cell lysis with further inflammation signals (Fernandes-Alnemri et al., 2007; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9)."}

{"project":"LitCovid-sample-PD-FMA","denotations":[{"id":"T423","span":{"begin":37,"end":44},"obj":"Body_part"},{"id":"T424","span":{"begin":84,"end":91},"obj":"Body_part"},{"id":"T425","span":{"begin":111,"end":118},"obj":"Body_part"},{"id":"T426","span":{"begin":159,"end":166},"obj":"Body_part"},{"id":"T427","span":{"begin":287,"end":296},"obj":"Body_part"},{"id":"T428","span":{"begin":310,"end":314},"obj":"Body_part"}],"attributes":[{"id":"A423","pred":"fma_id","subj":"T423","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A424","pred":"fma_id","subj":"T424","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A425","pred":"fma_id","subj":"T425","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A426","pred":"fma_id","subj":"T426","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A427","pred":"fma_id","subj":"T427","obj":"http://purl.org/sig/ont/fma/fma84050"},{"id":"A428","pred":"fma_id","subj":"T428","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"One common PRR is NOD-like receptors protein 3 (NLRP3), which forms together with a protein caspase activating protein (ASC or apoptosis-associated speck-like protein containing a caspase recruitment domain) and pro-caspase 1, the inflammasome unit capable of recruiting proinflammatory cytokines and inducing cell lysis with further inflammation signals (Fernandes-Alnemri et al., 2007; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9)."}

{"project":"LitCovid-sample-PD-MONDO","denotations":[{"id":"T368","span":{"begin":18,"end":21},"obj":"Disease"},{"id":"T369","span":{"begin":120,"end":123},"obj":"Disease"},{"id":"T370","span":{"begin":334,"end":346},"obj":"Disease"}],"attributes":[{"id":"A368","pred":"mondo_id","subj":"T368","obj":"http://purl.obolibrary.org/obo/MONDO_0007435"},{"id":"A369","pred":"mondo_id","subj":"T369","obj":"http://purl.obolibrary.org/obo/MONDO_0019018"},{"id":"A370","pred":"mondo_id","subj":"T370","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"}],"text":"One common PRR is NOD-like receptors protein 3 (NLRP3), which forms together with a protein caspase activating protein (ASC or apoptosis-associated speck-like protein containing a caspase recruitment domain) and pro-caspase 1, the inflammasome unit capable of recruiting proinflammatory cytokines and inducing cell lysis with further inflammation signals (Fernandes-Alnemri et al., 2007; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9)."}

{"project":"LitCovid-sample-PD-GO-BP-0","denotations":[{"id":"T126","span":{"begin":92,"end":110},"obj":"http://purl.obolibrary.org/obo/GO_0006919"},{"id":"T127","span":{"begin":127,"end":136},"obj":"http://purl.obolibrary.org/obo/GO_0006915"},{"id":"T128","span":{"begin":127,"end":136},"obj":"http://purl.obolibrary.org/obo/GO_0097194"},{"id":"T129","span":{"begin":315,"end":320},"obj":"http://purl.obolibrary.org/obo/GO_0019835"},{"id":"T130","span":{"begin":334,"end":346},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"One common PRR is NOD-like receptors protein 3 (NLRP3), which forms together with a protein caspase activating protein (ASC or apoptosis-associated speck-like protein containing a caspase recruitment domain) and pro-caspase 1, the inflammasome unit capable of recruiting proinflammatory cytokines and inducing cell lysis with further inflammation signals (Fernandes-Alnemri et al., 2007; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9)."}

{"project":"LitCovid-sample-GO-BP","denotations":[{"id":"T127","span":{"begin":92,"end":110},"obj":"http://purl.obolibrary.org/obo/GO_0006919"},{"id":"T128","span":{"begin":127,"end":136},"obj":"http://purl.obolibrary.org/obo/GO_0097194"},{"id":"T129","span":{"begin":127,"end":136},"obj":"http://purl.obolibrary.org/obo/GO_0006915"},{"id":"T130","span":{"begin":315,"end":320},"obj":"http://purl.obolibrary.org/obo/GO_0019835"},{"id":"T131","span":{"begin":334,"end":346},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"One common PRR is NOD-like receptors protein 3 (NLRP3), which forms together with a protein caspase activating protein (ASC or apoptosis-associated speck-like protein containing a caspase recruitment domain) and pro-caspase 1, the inflammasome unit capable of recruiting proinflammatory cytokines and inducing cell lysis with further inflammation signals (Fernandes-Alnemri et al., 2007; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"1727","span":{"begin":48,"end":53},"obj":"Gene"},{"id":"1728","span":{"begin":216,"end":225},"obj":"Gene"},{"id":"1731","span":{"begin":334,"end":346},"obj":"Disease"}],"attributes":[{"id":"A1727","pred":"tao:has_database_id","subj":"1727","obj":"Gene:114548"},{"id":"A1728","pred":"tao:has_database_id","subj":"1728","obj":"Gene:834"},{"id":"A1731","pred":"tao:has_database_id","subj":"1731","obj":"MESH:D007249"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"One common PRR is NOD-like receptors protein 3 (NLRP3), which forms together with a protein caspase activating protein (ASC or apoptosis-associated speck-like protein containing a caspase recruitment domain) and pro-caspase 1, the inflammasome unit capable of recruiting proinflammatory cytokines and inducing cell lysis with further inflammation signals (Fernandes-Alnemri et al., 2007; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T378","span":{"begin":0,"end":445},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"One common PRR is NOD-like receptors protein 3 (NLRP3), which forms together with a protein caspase activating protein (ASC or apoptosis-associated speck-like protein containing a caspase recruitment domain) and pro-caspase 1, the inflammasome unit capable of recruiting proinflammatory cytokines and inducing cell lysis with further inflammation signals (Fernandes-Alnemri et al., 2007; Schroder and Tschopp, 2010; Wree et al., 2014; Figure 9)."}