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PMC:7556165 / 44952-45781 JSONTXT

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LitCovid-sample-MedDRA

Id Subject Object Predicate Lexical cue meddra_id
T79 484-494 http://purl.bioontology.org/ontology/MEDDRA/10022891 denotes microscopy http://purl.bioontology.org/ontology/MEDDRA/10069374

LitCovid-sample-CHEBI

Id Subject Object Predicate Lexical cue chebi_id
T154 198-205 Chemical denotes protein http://purl.obolibrary.org/obo/CHEBI_36080
T155 767-775 Chemical denotes proteins http://purl.obolibrary.org/obo/CHEBI_36080

LitCovid-sample-PD-NCBITaxon

Id Subject Object Predicate Lexical cue ncbi_taxonomy_id
T200 6-16 Species denotes SARS-CoV-2 NCBItxid:2697049
T201 6-10 Species denotes SARS NCBItxid:694009
T202 21-29 Species denotes SARS-CoV NCBItxid:694009
T203 21-25 Species denotes SARS NCBItxid:694009
T204 97-107 Species denotes SARS-CoV-2 NCBItxid:2697049
T205 97-101 Species denotes SARS NCBItxid:694009
T206 138-146 Species denotes SARS-CoV NCBItxid:694009
T207 138-142 Species denotes SARS NCBItxid:694009
T208 148-156 Species denotes SARS-CoV NCBItxid:694009
T209 148-152 Species denotes SARS NCBItxid:694009
T210 274-284 Species denotes SARS-CoV-2 NCBItxid:2697049
T211 274-278 Species denotes SARS NCBItxid:694009
T212 331-339 Species denotes SARS-CoV NCBItxid:694009
T213 331-335 Species denotes SARS NCBItxid:694009
T214 447-457 Species denotes SARS-CoV-2 NCBItxid:2697049
T215 447-451 Species denotes SARS NCBItxid:694009
T216 503-513 Species denotes SARS-CoV-2 NCBItxid:2697049
T217 503-507 Species denotes SARS NCBItxid:694009
T218 684-688 Species denotes MERS NCBItxid:1335626

LitCovid-sample-sentences

Id Subject Object Predicate Lexical cue
T276 0-147 Sentence denotes Since SARS-CoV-2 and SARS-CoV share the same host cell receptor, it was early questioned whether SARS-CoV-2 retains the same RBD motif of SARS-CoV.
T277 148-224 Sentence denotes SARS-CoV RBD corresponds to residues 306–527 of S protein (Li et al., 2005).
T278 225-364 Sentence denotes Sequence analysis shows that residues 319–541 of SARS-CoV-2 (S319–341) share 73.9% sequence identity with SARS-CoV RBD (Wang et al., 2020).
T279 365-495 Sentence denotes Accordingly, Wang et al. (2020) clearly demonstrated that S319–341 corresponds to SARS-CoV-2 RBD by immunofluorescence microscopy.
T280 496-699 Sentence denotes Indeed SARS-CoV-2 S1 and S319–341 positively colocalized with GFP-tagged ACE2 expressed on cell surface of HEK cells, whereas this interaction did not occur with membrane-expressed hDPP4 (MERS receptor).
T281 700-829 Sentence denotes Additionally, soluble ACE2 inhibited the interaction between viral proteins and ACE2-expressing cells in a dose-dependent manner.

LitCovid-sample-Pubtator

Id Subject Object Predicate Lexical cue pubann:denotes
1217 569-573 Gene denotes ACE2 Gene:59272
1218 677-682 Gene denotes hDPP4 Gene:1803
1219 722-726 Gene denotes ACE2 Gene:59272
1220 780-784 Gene denotes ACE2 Gene:59272
1221 658-666 Gene denotes membrane Gene:43740571
1222 6-16 Species denotes SARS-CoV-2 Tax:2697049
1223 21-29 Species denotes SARS-CoV Tax:694009
1224 97-107 Species denotes SARS-CoV-2 Tax:2697049
1225 138-146 Species denotes SARS-CoV Tax:694009
1226 148-156 Species denotes SARS-CoV Tax:694009
1227 274-284 Species denotes SARS-CoV-2 Tax:2697049
1228 331-339 Species denotes SARS-CoV Tax:694009
1229 447-457 Species denotes SARS-CoV-2 Tax:2697049
1230 503-513 Species denotes SARS-CoV-2 Tax:2697049
1231 603-606 CellLine denotes HEK CVCL:M624

LitCovid-sample-UniProt

Id Subject Object Predicate Lexical cue uniprot_id
T4971 125-128 Protein denotes RBD https://www.uniprot.org/uniprot/Q63492|https://www.uniprot.org/uniprot/Q63491|https://www.uniprot.org/uniprot/Q62815|https://www.uniprot.org/uniprot/Q62691|https://www.uniprot.org/uniprot/Q01542|https://www.uniprot.org/uniprot/P27732|https://www.uniprot.org/uniprot/O09024|https://www.uniprot.org/uniprot/O09023|https://www.uniprot.org/uniprot/O09022
T4980 157-160 Protein denotes RBD https://www.uniprot.org/uniprot/Q63492|https://www.uniprot.org/uniprot/Q63491|https://www.uniprot.org/uniprot/Q62815|https://www.uniprot.org/uniprot/Q62691|https://www.uniprot.org/uniprot/Q01542|https://www.uniprot.org/uniprot/P27732|https://www.uniprot.org/uniprot/O09024|https://www.uniprot.org/uniprot/O09023|https://www.uniprot.org/uniprot/O09022
T4989 196-205 Protein denotes S protein https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9
T5022 340-343 Protein denotes RBD https://www.uniprot.org/uniprot/Q63492|https://www.uniprot.org/uniprot/Q63491|https://www.uniprot.org/uniprot/Q62815|https://www.uniprot.org/uniprot/Q62691|https://www.uniprot.org/uniprot/Q01542|https://www.uniprot.org/uniprot/P27732|https://www.uniprot.org/uniprot/O09024|https://www.uniprot.org/uniprot/O09023|https://www.uniprot.org/uniprot/O09022
T5031 458-461 Protein denotes RBD https://www.uniprot.org/uniprot/Q63492|https://www.uniprot.org/uniprot/Q63491|https://www.uniprot.org/uniprot/Q62815|https://www.uniprot.org/uniprot/Q62691|https://www.uniprot.org/uniprot/Q01542|https://www.uniprot.org/uniprot/P27732|https://www.uniprot.org/uniprot/O09024|https://www.uniprot.org/uniprot/O09023|https://www.uniprot.org/uniprot/O09022
T5040 569-573 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T5041 603-606 Protein denotes HEK https://www.uniprot.org/uniprot/Q9H2V4|https://www.uniprot.org/uniprot/Q9H2V3|https://www.uniprot.org/uniprot/P29320
T5044 722-726 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6
T5045 780-784 Protein denotes ACE2 https://www.uniprot.org/uniprot/Q9UFZ6

LitCovid-sample-PD-IDO

Id Subject Object Predicate Lexical cue
T185 45-49 http://purl.obolibrary.org/obo/IDO_0000531 denotes host
T186 50-54 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T187 587-591 http://purl.obolibrary.org/obo/CL_0000000 denotes cell
T188 607-612 http://purl.obolibrary.org/obo/CL_0000000 denotes cells
T189 796-801 http://purl.obolibrary.org/obo/CL_0000000 denotes cells

LitCovid-sample-PD-FMA

Id Subject Object Predicate Lexical cue fma_id
T375 50-54 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T376 198-205 Body_part denotes protein http://purl.org/sig/ont/fma/fma67257
T377 587-599 Body_part denotes cell surface http://purl.org/sig/ont/fma/fma67653
T378 587-591 Body_part denotes cell http://purl.org/sig/ont/fma/fma68646
T379 607-612 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646
T380 767-775 Body_part denotes proteins http://purl.org/sig/ont/fma/fma67257
T381 796-801 Body_part denotes cells http://purl.org/sig/ont/fma/fma68646

LitCovid-sample-PD-MONDO

Id Subject Object Predicate Lexical cue mondo_id
T181 6-16 Disease denotes SARS-CoV-2 http://purl.obolibrary.org/obo/MONDO_0100096
T182 6-10 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T183 21-29 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T184 21-25 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T185 97-107 Disease denotes SARS-CoV-2 http://purl.obolibrary.org/obo/MONDO_0100096
T186 97-101 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T187 138-146 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T188 138-142 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T189 148-156 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T190 148-152 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T191 274-284 Disease denotes SARS-CoV-2 http://purl.obolibrary.org/obo/MONDO_0100096
T192 274-278 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T193 331-339 Disease denotes SARS-CoV http://purl.obolibrary.org/obo/MONDO_0005091
T194 331-335 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T195 447-457 Disease denotes SARS-CoV-2 http://purl.obolibrary.org/obo/MONDO_0100096
T196 447-451 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091
T197 503-513 Disease denotes SARS-CoV-2 http://purl.obolibrary.org/obo/MONDO_0100096
T198 503-507 Disease denotes SARS http://purl.obolibrary.org/obo/MONDO_0005091

LitCovid-PubTator

Id Subject Object Predicate Lexical cue tao:has_database_id
1217 569-573 Gene denotes ACE2 Gene:59272
1218 677-682 Gene denotes hDPP4 Gene:1803
1219 722-726 Gene denotes ACE2 Gene:59272
1220 780-784 Gene denotes ACE2 Gene:59272
1221 658-666 Gene denotes membrane Gene:43740571
1222 6-16 Species denotes SARS-CoV-2 Tax:2697049
1223 21-29 Species denotes SARS-CoV Tax:694009
1224 97-107 Species denotes SARS-CoV-2 Tax:2697049
1225 138-146 Species denotes SARS-CoV Tax:694009
1226 148-156 Species denotes SARS-CoV Tax:694009
1227 274-284 Species denotes SARS-CoV-2 Tax:2697049
1228 331-339 Species denotes SARS-CoV Tax:694009
1229 447-457 Species denotes SARS-CoV-2 Tax:2697049
1230 503-513 Species denotes SARS-CoV-2 Tax:2697049
1231 603-606 CellLine denotes HEK CVCL:M624

LitCovid-sentences

Id Subject Object Predicate Lexical cue
T276 0-147 Sentence denotes Since SARS-CoV-2 and SARS-CoV share the same host cell receptor, it was early questioned whether SARS-CoV-2 retains the same RBD motif of SARS-CoV.
T277 148-224 Sentence denotes SARS-CoV RBD corresponds to residues 306–527 of S protein (Li et al., 2005).
T278 225-364 Sentence denotes Sequence analysis shows that residues 319–541 of SARS-CoV-2 (S319–341) share 73.9% sequence identity with SARS-CoV RBD (Wang et al., 2020).
T279 365-495 Sentence denotes Accordingly, Wang et al. (2020) clearly demonstrated that S319–341 corresponds to SARS-CoV-2 RBD by immunofluorescence microscopy.
T280 496-699 Sentence denotes Indeed SARS-CoV-2 S1 and S319–341 positively colocalized with GFP-tagged ACE2 expressed on cell surface of HEK cells, whereas this interaction did not occur with membrane-expressed hDPP4 (MERS receptor).
T281 700-829 Sentence denotes Additionally, soluble ACE2 inhibited the interaction between viral proteins and ACE2-expressing cells in a dose-dependent manner.