PMC:7543426 / 26827-27971 JSONTXT

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Further pathological examination of brain tissues needs to be performed where cytoplasmic viral staining, immunohistochemical, and electron microscope analysis may shed further light on the neuropathological manifestations of COVID-19. It is important that autopsy studies are given priority. Whole-body complete autopsy studies from across a wide range of geographical background, age, ethnic group, and comorbidities [10, 34, 35] are required to define the pathogenesis and the complete spectrum of pathology in 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