PMC:7543426 / 23093-23679 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T246","span":{"begin":4,"end":8},"obj":"Body_part"},{"id":"T247","span":{"begin":80,"end":84},"obj":"Body_part"},{"id":"T248","span":{"begin":85,"end":92},"obj":"Body_part"},{"id":"T249","span":{"begin":276,"end":285},"obj":"Body_part"},{"id":"T250","span":{"begin":297,"end":308},"obj":"Body_part"},{"id":"T251","span":{"begin":426,"end":435},"obj":"Body_part"},{"id":"T252","span":{"begin":489,"end":502},"obj":"Body_part"}],"attributes":[{"id":"A246","pred":"fma_id","subj":"T246","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A247","pred":"fma_id","subj":"T247","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A248","pred":"fma_id","subj":"T248","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A249","pred":"fma_id","subj":"T249","obj":"http://purl.org/sig/ont/fma/fma66835"},{"id":"A250","pred":"fma_id","subj":"T250","obj":"http://purl.org/sig/ont/fma/fma62499"},{"id":"A251","pred":"fma_id","subj":"T251","obj":"http://purl.org/sig/ont/fma/fma63194"},{"id":"A252","pred":"fma_id","subj":"T252","obj":"http://purl.org/sig/ont/fma/fma62870"}],"text":"Our lung pathology findings were similar to those seen in a study of postmortem lung tissues from northern Italy of 33 males and 5 female patients, with an average age of 69 years (range 32–86) [17]. In addition, using electron microscopy we identified viral particles in the cytoplasm of type II pneumocytes—the main target of viral infection [18]. Interestingly, all the histological hallmarks of interstitial pneumonia and capillary damage were prominent in all 22 COVID-19 cases, with T lymphocytes being prominent in vascular infiltrates (vasculitis) and interstitial inflammation."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T126","span":{"begin":4,"end":8},"obj":"Body_part"},{"id":"T127","span":{"begin":80,"end":84},"obj":"Body_part"},{"id":"T128","span":{"begin":426,"end":435},"obj":"Body_part"}],"attributes":[{"id":"A126","pred":"uberon_id","subj":"T126","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A127","pred":"uberon_id","subj":"T127","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A128","pred":"uberon_id","subj":"T128","obj":"http://purl.obolibrary.org/obo/UBERON_0001982"}],"text":"Our lung pathology findings were similar to those seen in a study of postmortem lung tissues from northern Italy of 33 males and 5 female patients, with an average age of 69 years (range 32–86) [17]. In addition, using electron microscopy we identified viral particles in the cytoplasm of type II pneumocytes—the main target of viral infection [18]. Interestingly, all the histological hallmarks of interstitial pneumonia and capillary damage were prominent in all 22 COVID-19 cases, with T lymphocytes being prominent in vascular infiltrates (vasculitis) and interstitial inflammation."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T167","span":{"begin":328,"end":343},"obj":"Disease"},{"id":"T168","span":{"begin":334,"end":343},"obj":"Disease"},{"id":"T169","span":{"begin":412,"end":421},"obj":"Disease"},{"id":"T170","span":{"begin":468,"end":476},"obj":"Disease"},{"id":"T171","span":{"begin":544,"end":554},"obj":"Disease"},{"id":"T172","span":{"begin":573,"end":585},"obj":"Disease"}],"attributes":[{"id":"A167","pred":"mondo_id","subj":"T167","obj":"http://purl.obolibrary.org/obo/MONDO_0005108"},{"id":"A168","pred":"mondo_id","subj":"T168","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A169","pred":"mondo_id","subj":"T169","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A170","pred":"mondo_id","subj":"T170","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A171","pred":"mondo_id","subj":"T171","obj":"http://purl.obolibrary.org/obo/MONDO_0018882"},{"id":"A172","pred":"mondo_id","subj":"T172","obj":"http://purl.obolibrary.org/obo/MONDO_0021166"}],"text":"Our lung pathology findings were similar to those seen in a study of postmortem lung tissues from northern Italy of 33 males and 5 female patients, with an average age of 69 years (range 32–86) [17]. In addition, using electron microscopy we identified viral particles in the cytoplasm of type II pneumocytes—the main target of viral infection [18]. Interestingly, all the histological hallmarks of interstitial pneumonia and capillary damage were prominent in all 22 COVID-19 cases, with T lymphocytes being prominent in vascular infiltrates (vasculitis) and interstitial inflammation."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T349","span":{"begin":4,"end":8},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T350","span":{"begin":4,"end":8},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T351","span":{"begin":58,"end":59},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T352","span":{"begin":80,"end":84},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T353","span":{"begin":80,"end":84},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T354","span":{"begin":119,"end":124},"obj":"http://purl.obolibrary.org/obo/UBERON_0003101"},{"id":"T355","span":{"begin":119,"end":124},"obj":"http://www.ebi.ac.uk/efo/EFO_0000970"},{"id":"T356","span":{"begin":131,"end":137},"obj":"http://purl.obolibrary.org/obo/UBERON_0003100"},{"id":"T357","span":{"begin":345,"end":347},"obj":"http://purl.obolibrary.org/obo/CLO_0050510"},{"id":"T358","span":{"begin":465,"end":467},"obj":"http://purl.obolibrary.org/obo/CLO_0050507"}],"text":"Our lung pathology findings were similar to those seen in a study of postmortem lung tissues from northern Italy of 33 males and 5 female patients, with an average age of 69 years (range 32–86) [17]. In addition, using electron microscopy we identified viral particles in the cytoplasm of type II pneumocytes—the main target of viral infection [18]. Interestingly, all the histological hallmarks of interstitial pneumonia and capillary damage were prominent in all 22 COVID-19 cases, with T lymphocytes being prominent in vascular infiltrates (vasculitis) and interstitial inflammation."}

{"project":"LitCovid-PubTator","denotations":[{"id":"600","span":{"begin":138,"end":146},"obj":"Species"},{"id":"601","span":{"begin":328,"end":343},"obj":"Disease"},{"id":"602","span":{"begin":412,"end":421},"obj":"Disease"},{"id":"603","span":{"begin":468,"end":476},"obj":"Disease"},{"id":"604","span":{"begin":544,"end":554},"obj":"Disease"},{"id":"605","span":{"begin":573,"end":585},"obj":"Disease"}],"attributes":[{"id":"A600","pred":"tao:has_database_id","subj":"600","obj":"Tax:9606"},{"id":"A601","pred":"tao:has_database_id","subj":"601","obj":"MESH:D001102"},{"id":"A602","pred":"tao:has_database_id","subj":"602","obj":"MESH:D011014"},{"id":"A603","pred":"tao:has_database_id","subj":"603","obj":"MESH:C000657245"},{"id":"A604","pred":"tao:has_database_id","subj":"604","obj":"MESH:D014657"},{"id":"A605","pred":"tao:has_database_id","subj":"605","obj":"MESH:D007249"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Our lung pathology findings were similar to those seen in a study of postmortem lung tissues from northern Italy of 33 males and 5 female patients, with an average age of 69 years (range 32–86) [17]. In addition, using electron microscopy we identified viral particles in the cytoplasm of type II pneumocytes—the main target of viral infection [18]. Interestingly, all the histological hallmarks of interstitial pneumonia and capillary damage were prominent in all 22 COVID-19 cases, with T lymphocytes being prominent in vascular infiltrates (vasculitis) and interstitial inflammation."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T78","span":{"begin":412,"end":421},"obj":"Phenotype"},{"id":"T79","span":{"begin":544,"end":554},"obj":"Phenotype"}],"attributes":[{"id":"A78","pred":"hp_id","subj":"T78","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A79","pred":"hp_id","subj":"T79","obj":"http://purl.obolibrary.org/obo/HP_0002633"}],"text":"Our lung pathology findings were similar to those seen in a study of postmortem lung tissues from northern Italy of 33 males and 5 female patients, with an average age of 69 years (range 32–86) [17]. In addition, using electron microscopy we identified viral particles in the cytoplasm of type II pneumocytes—the main target of viral infection [18]. Interestingly, all the histological hallmarks of interstitial pneumonia and capillary damage were prominent in all 22 COVID-19 cases, with T lymphocytes being prominent in vascular infiltrates (vasculitis) and interstitial inflammation."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T32","span":{"begin":328,"end":343},"obj":"http://purl.obolibrary.org/obo/GO_0016032"},{"id":"T33","span":{"begin":573,"end":585},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"Our lung pathology findings were similar to those seen in a study of postmortem lung tissues from northern Italy of 33 males and 5 female patients, with an average age of 69 years (range 32–86) [17]. In addition, using electron microscopy we identified viral particles in the cytoplasm of type II pneumocytes—the main target of viral infection [18]. Interestingly, all the histological hallmarks of interstitial pneumonia and capillary damage were prominent in all 22 COVID-19 cases, with T lymphocytes being prominent in vascular infiltrates (vasculitis) and interstitial inflammation."}

{"project":"LitCovid-sentences","denotations":[{"id":"T270","span":{"begin":0,"end":199},"obj":"Sentence"},{"id":"T271","span":{"begin":200,"end":349},"obj":"Sentence"},{"id":"T272","span":{"begin":350,"end":586},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Our lung pathology findings were similar to those seen in a study of postmortem lung tissues from northern Italy of 33 males and 5 female patients, with an average age of 69 years (range 32–86) [17]. In addition, using electron microscopy we identified viral particles in the cytoplasm of type II pneumocytes—the main target of viral infection [18]. Interestingly, all the histological hallmarks of interstitial pneumonia and capillary damage were prominent in all 22 COVID-19 cases, with T lymphocytes being prominent in vascular infiltrates (vasculitis) and interstitial inflammation."}