PMC:7441788 / 8488-9599
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T36 | 336-343 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T37 | 382-393 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
T38 | 561-564 | Body_part | denotes | MHC | http://purl.org/sig/ont/fma/fma84079 |
T39 | 638-642 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T40 | 693-702 | Body_part | denotes | cytokines | http://purl.org/sig/ont/fma/fma84050 |
T41 | 742-747 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T42 | 754-759 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T43 | 923-930 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T44 | 939-942 | Body_part | denotes | MHC | http://purl.org/sig/ont/fma/fma84079 |
T45 | 947-979 | Body_part | denotes | major histocompatibility complex | http://purl.org/sig/ont/fma/fma84079 |
T46 | 1063-1065 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
T47 | 1067-1078 | Body_part | denotes | interleukin | http://purl.org/sig/ont/fma/fma86578 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T68 | 204-212 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T69 | 800-808 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T70 | 810-834 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T71 | 1087-1092 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T88 | 410-418 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T89 | 497-507 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
T90 | 630-633 | http://purl.obolibrary.org/obo/PR_000001004 | denotes | CD4 |
T91 | 636-642 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cell |
T92 | 652-661 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signaling |
T93 | 726-736 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activation |
T94 | 740-747 | http://purl.obolibrary.org/obo/CL_0000084 | denotes | T cells |
T95 | 752-759 | http://purl.obolibrary.org/obo/CL_0000236 | denotes | B cells |
T96 | 913-922 | http://purl.obolibrary.org/obo/CLO_0001658 | denotes | activated |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T94 | 65-67 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
T95 | 129-131 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
T96 | 162-171 | Chemical | denotes | antiviral | http://purl.obolibrary.org/obo/CHEBI_22587 |
T97 | 336-343 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T98 | 366-377 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
T99 | 373-377 | Chemical | denotes | acid | http://purl.obolibrary.org/obo/CHEBI_37527 |
T100 | 382-393 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
T101 | 571-573 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
T102 | 767-778 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
T103 | 836-838 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
T104 | 840-851 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
T105 | 858-876 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
T106 | 905-912 | Chemical | denotes | mitogen | http://purl.obolibrary.org/obo/CHEBI_52290 |
T107 | 923-930 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T108 | 943-945 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
T109 | 986-988 | Chemical | denotes | II | http://purl.obolibrary.org/obo/CHEBI_74067 |
T110 | 1021-1035 | Chemical | denotes | cyclic GMP-AMP | http://purl.obolibrary.org/obo/CHEBI_71580 |
T111 | 1028-1031 | Chemical | denotes | GMP | http://purl.obolibrary.org/obo/CHEBI_17345|http://purl.obolibrary.org/obo/CHEBI_58115 |
T113 | 1032-1035 | Chemical | denotes | AMP | http://purl.obolibrary.org/obo/CHEBI_16027|http://purl.obolibrary.org/obo/CHEBI_28971|http://purl.obolibrary.org/obo/CHEBI_456215 |
T116 | 1051-1061 | Chemical | denotes | interferon | http://purl.obolibrary.org/obo/CHEBI_52999 |
T117 | 1063-1065 | Chemical | denotes | IL | http://purl.obolibrary.org/obo/CHEBI_63895|http://purl.obolibrary.org/obo/CHEBI_74072 |
LitCovid-sample-MedDRA
Id | Subject | Object | Predicate | Lexical cue | meddra_id |
---|---|---|---|---|---|
T6 | 767-796 | http://purl.bioontology.org/ontology/MEDDRA/10022891 | denotes | angiotensin-converting enzyme | http://purl.bioontology.org/ontology/MEDDRA/10050289 |
LitCovid-sample-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T67 | 65-67 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
T68 | 129-131 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
T69 | 336-343 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T70 | 366-377 | Chemical | denotes | sialic acid | http://purl.obolibrary.org/obo/CHEBI_26667 |
T71 | 382-393 | Chemical | denotes | ganglioside | http://purl.obolibrary.org/obo/CHEBI_28892 |
T72 | 767-778 | Chemical | denotes | angiotensin | http://purl.obolibrary.org/obo/CHEBI_48433 |
T73 | 836-838 | Chemical | denotes | CQ | http://purl.obolibrary.org/obo/CHEBI_3638 |
T74 | 840-851 | Chemical | denotes | chloroquine | http://purl.obolibrary.org/obo/CHEBI_3638 |
T75 | 858-876 | Chemical | denotes | hydroxychloroquine | http://purl.obolibrary.org/obo/CHEBI_5801 |
T76 | 923-930 | Chemical | denotes | protein | http://purl.obolibrary.org/obo/CHEBI_36080 |
T77 | 1021-1035 | Chemical | denotes | cyclic GMP-AMP | http://purl.obolibrary.org/obo/CHEBI_71580 |
LitCovid-sample-PD-NCBITaxon
Id | Subject | Object | Predicate | Lexical cue | ncbi_taxonomy_id |
---|---|---|---|---|---|
T72 | 204-212 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T73 | 800-808 | Species | denotes | COVID-19 | NCBItxid:2697049 |
T74 | 810-834 | Species | denotes | coronavirus disease 2019 | NCBItxid:2697049 |
LitCovid-sample-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T68 | 0-9 | Sentence | denotes | Figure 1. |
T69 | 10-128 | Sentence | denotes | Schematic representation of the possible mechanisms of CQ/HCQ against CoVs replication and modulating immune response. |
T70 | 129-760 | Sentence | denotes | CQ/HCQ may synergistically exert antiviral and immunomodulatory effects on COVID-19 through multiple mechanisms including hindering the receptor recognition process by influencing the affinity of ACE2 and S protein, and the affinity for sialic acid and ganglioside; inhibiting the membrane fusion process by suppressing endolysosome acidification; suppressing the p38 activation and affecting host defense machinery, and preventing MHC class II expression (block expression of CD154 on the surface of CD4 + T cell) and TLR signaling and reducing the production of cytokines through inhibiting the activation of T cells and B cells. |
T71 | 761-1111 | Sentence | denotes | ACE2, angiotensin-converting enzyme 2; COVID-19, coronavirus disease 2019; CQ, chloroquine; HCQ, hydroxychloroquine; CoVs, coronaviruses; MAPK, mitogen-activated protein kinase; MHC-II, major histocompatibility complex class II; TLR, toll-like receptor; cGAS, cyclic GMP-AMP synthase; IFN, interferon; IL, interleukin; TNF-α, tumor necrosis factor-α. |
LitCovid-sample-Pubtator
Id | Subject | Object | Predicate | Lexical cue | pubann:denotes |
---|---|---|---|---|---|
322 | 325-329 | Gene | denotes | ACE2 | Gene:59272 |
323 | 493-496 | Gene | denotes | p38 | Gene:1432 |
324 | 606-611 | Gene | denotes | CD154 | Gene:959 |
325 | 630-633 | Gene | denotes | CD4 | Gene:920 |
326 | 80-84 | Species | denotes | CoVs | Tax:11118 |
327 | 65-67 | Chemical | denotes | CQ | MESH:D002738 |
328 | 68-71 | Chemical | denotes | HCQ | MESH:D006886 |
329 | 204-212 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-sample-UniProt
Id | Subject | Object | Predicate | Lexical cue | uniprot_id |
---|---|---|---|---|---|
T121 | 325-329 | Protein | denotes | ACE2 | https://www.uniprot.org/uniprot/Q9UFZ6 |
T122 | 334-343 | Protein | denotes | S protein | https://www.uniprot.org/uniprot/Q9UIP0|https://www.uniprot.org/uniprot/Q9UIN9|https://www.uniprot.org/uniprot/Q9UIN8|https://www.uniprot.org/uniprot/Q9UIN7|https://www.uniprot.org/uniprot/Q9UIN6|https://www.uniprot.org/uniprot/Q9UBH8|https://www.uniprot.org/uniprot/Q9NRH8|https://www.uniprot.org/uniprot/Q9NRH7|https://www.uniprot.org/uniprot/Q9NRH6|https://www.uniprot.org/uniprot/Q9NRH5|https://www.uniprot.org/uniprot/Q9NRH4|https://www.uniprot.org/uniprot/Q9NPG5|https://www.uniprot.org/uniprot/Q9NPE0|https://www.uniprot.org/uniprot/Q9NP52|https://www.uniprot.org/uniprot/Q95IF9|https://www.uniprot.org/uniprot/Q8N5P3|https://www.uniprot.org/uniprot/Q8IZU6|https://www.uniprot.org/uniprot/Q8IZU5|https://www.uniprot.org/uniprot/Q8IZU4|https://www.uniprot.org/uniprot/Q86Z04|https://www.uniprot.org/uniprot/Q7YR44|https://www.uniprot.org/uniprot/Q7LA71|https://www.uniprot.org/uniprot/Q7LA70|https://www.uniprot.org/uniprot/Q5STD2|https://www.uniprot.org/uniprot/Q5SQ85|https://www.uniprot.org/uniprot/Q1XI16|https://www.uniprot.org/uniprot/Q1XI12|https://www.uniprot.org/uniprot/Q15517|https://www.uniprot.org/uniprot/O43509|https://www.uniprot.org/uniprot/O19084|https://www.uniprot.org/uniprot/B0UYZ7|https://www.uniprot.org/uniprot/B0S7V2|https://www.uniprot.org/uniprot/A5A6L9 |
T155 | 493-496 | Protein | denotes | p38 | https://www.uniprot.org/uniprot/Q9Y4Y1|https://www.uniprot.org/uniprot/Q9Y2S7|https://www.uniprot.org/uniprot/Q9UFX6|https://www.uniprot.org/uniprot/Q9UFG0|https://www.uniprot.org/uniprot/Q9Q6X7|https://www.uniprot.org/uniprot/Q9PY95|https://www.uniprot.org/uniprot/Q9P060|https://www.uniprot.org/uniprot/Q9NV58|https://www.uniprot.org/uniprot/Q9H8M8|https://www.uniprot.org/uniprot/Q9H5H9|https://www.uniprot.org/uniprot/Q96JE4|https://www.uniprot.org/uniprot/Q96IL6|https://www.uniprot.org/uniprot/Q96HJ0|https://www.uniprot.org/uniprot/Q96GA9|https://www.uniprot.org/uniprot/Q7TD18|https://www.uniprot.org/uniprot/Q64010|https://www.uniprot.org/uniprot/Q63768|https://www.uniprot.org/uniprot/Q52LG1|https://www.uniprot.org/uniprot/Q04929|https://www.uniprot.org/uniprot/Q01552|https://www.uniprot.org/uniprot/P46108|https://www.uniprot.org/uniprot/P34717|https://www.uniprot.org/uniprot/P27586|https://www.uniprot.org/uniprot/P0C797|https://www.uniprot.org/uniprot/P0C796|https://www.uniprot.org/uniprot/P06663|https://www.uniprot.org/uniprot/P04383|https://www.uniprot.org/uniprot/O97628|https://www.uniprot.org/uniprot/O95433|https://www.uniprot.org/uniprot/D3DTH6|https://www.uniprot.org/uniprot/B4DUR9|https://www.uniprot.org/uniprot/B2R9L2|https://www.uniprot.org/uniprot/B2R846|https://www.uniprot.org/uniprot/B0LPE8|https://www.uniprot.org/uniprot/A8MWE8|https://www.uniprot.org/uniprot/A3KCU9 |
T191 | 606-611 | Protein | denotes | CD154 | https://www.uniprot.org/uniprot/Q9Z2V2|https://www.uniprot.org/uniprot/Q9R254|https://www.uniprot.org/uniprot/Q9BDN3|https://www.uniprot.org/uniprot/Q9BDM7|https://www.uniprot.org/uniprot/Q9BDM3|https://www.uniprot.org/uniprot/Q9BDC7|https://www.uniprot.org/uniprot/Q95MQ5|https://www.uniprot.org/uniprot/P63305|https://www.uniprot.org/uniprot/P63304|https://www.uniprot.org/uniprot/P51749|https://www.uniprot.org/uniprot/P29965|https://www.uniprot.org/uniprot/P27548|https://www.uniprot.org/uniprot/O97626|https://www.uniprot.org/uniprot/O97605 |
T205 | 630-633 | Protein | denotes | CD4 | https://www.uniprot.org/uniprot/Q9XS78|https://www.uniprot.org/uniprot/Q9UDE5|https://www.uniprot.org/uniprot/Q5U066|https://www.uniprot.org/uniprot/Q4ZGK2|https://www.uniprot.org/uniprot/Q29617|https://www.uniprot.org/uniprot/Q29037|https://www.uniprot.org/uniprot/Q28217|https://www.uniprot.org/uniprot/Q08340|https://www.uniprot.org/uniprot/Q08339|https://www.uniprot.org/uniprot/Q08338|https://www.uniprot.org/uniprot/Q08336|https://www.uniprot.org/uniprot/P79196|https://www.uniprot.org/uniprot/P79185|https://www.uniprot.org/uniprot/P79184|https://www.uniprot.org/uniprot/P46630|https://www.uniprot.org/uniprot/P33705|https://www.uniprot.org/uniprot/P16004|https://www.uniprot.org/uniprot/P16003|https://www.uniprot.org/uniprot/P06332|https://www.uniprot.org/uniprot/P05542|https://www.uniprot.org/uniprot/P05540|https://www.uniprot.org/uniprot/P01730|https://www.uniprot.org/uniprot/O77593|https://www.uniprot.org/uniprot/O02805|https://www.uniprot.org/uniprot/D3DUS5|https://www.uniprot.org/uniprot/B2R737 |
T231 | 761-765 | Protein | denotes | ACE2 | https://www.uniprot.org/uniprot/Q9UFZ6 |
T232 | 767-798 | Protein | denotes | angiotensin-converting enzyme 2 | https://www.uniprot.org/uniprot/Q9UFZ6|https://www.uniprot.org/uniprot/Q9NRA7|https://www.uniprot.org/uniprot/Q9BYF1|https://www.uniprot.org/uniprot/Q99N71|https://www.uniprot.org/uniprot/Q99N70|https://www.uniprot.org/uniprot/Q8R0I0|https://www.uniprot.org/uniprot/Q86WT0|https://www.uniprot.org/uniprot/Q6UWP0|https://www.uniprot.org/uniprot/Q5RFN1|https://www.uniprot.org/uniprot/Q5EGZ1|https://www.uniprot.org/uniprot/Q58DD0|https://www.uniprot.org/uniprot/Q56NL1|https://www.uniprot.org/uniprot/Q56H28|https://www.uniprot.org/uniprot/Q2PGE2|https://www.uniprot.org/uniprot/C7ECU1 |
T247 | 1015-1019 | Protein | denotes | cGAS | https://www.uniprot.org/uniprot/Q96E45|https://www.uniprot.org/uniprot/Q8N884|https://www.uniprot.org/uniprot/Q8C6L5|https://www.uniprot.org/uniprot/Q5SWL1|https://www.uniprot.org/uniprot/Q5SWL0|https://www.uniprot.org/uniprot/Q3ULW3|https://www.uniprot.org/uniprot/Q32NC9|https://www.uniprot.org/uniprot/Q14CV6|https://www.uniprot.org/uniprot/L0L2J9|https://www.uniprot.org/uniprot/I3LM39|https://www.uniprot.org/uniprot/E1BGN7|https://www.uniprot.org/uniprot/A7SFB5 |
T259 | 1021-1044 | Protein | denotes | cyclic GMP-AMP synthase | https://www.uniprot.org/uniprot/Q96E45|https://www.uniprot.org/uniprot/Q8N884|https://www.uniprot.org/uniprot/Q8C6L5|https://www.uniprot.org/uniprot/Q5SWL1|https://www.uniprot.org/uniprot/Q5SWL0|https://www.uniprot.org/uniprot/Q3ULW3|https://www.uniprot.org/uniprot/Q32NC9|https://www.uniprot.org/uniprot/Q14CV6|https://www.uniprot.org/uniprot/L0L2J9|https://www.uniprot.org/uniprot/I3LM39|https://www.uniprot.org/uniprot/E1BGN7|https://www.uniprot.org/uniprot/A7SFB5 |
T271 | 1051-1061 | Protein | denotes | interferon | https://www.uniprot.org/uniprot/P51527|https://www.uniprot.org/uniprot/P51526 |
T273 | 1087-1108 | Protein | denotes | tumor necrosis factor | https://www.uniprot.org/uniprot/Q9UIV3|https://www.uniprot.org/uniprot/Q9TTJ3|https://www.uniprot.org/uniprot/Q9P1Q2|https://www.uniprot.org/uniprot/Q9MYZ2|https://www.uniprot.org/uniprot/Q9JI27|https://www.uniprot.org/uniprot/Q9JI26|https://www.uniprot.org/uniprot/Q9BEA1|https://www.uniprot.org/uniprot/Q91VF3|https://www.uniprot.org/uniprot/Q8WNR1|https://www.uniprot.org/uniprot/Q8MKG8|https://www.uniprot.org/uniprot/Q8JFG3|https://www.uniprot.org/uniprot/Q8HZD9|https://www.uniprot.org/uniprot/Q8HZD6|https://www.uniprot.org/uniprot/Q8HYM0|https://www.uniprot.org/uniprot/Q75N23|https://www.uniprot.org/uniprot/Q6EE11|https://www.uniprot.org/uniprot/Q62326|https://www.uniprot.org/uniprot/Q5TM21|https://www.uniprot.org/uniprot/Q539C2|https://www.uniprot.org/uniprot/Q2MH05|https://www.uniprot.org/uniprot/P29553|https://www.uniprot.org/uniprot/P23563|https://www.uniprot.org/uniprot/P23383|https://www.uniprot.org/uniprot/P19101|https://www.uniprot.org/uniprot/P16599|https://www.uniprot.org/uniprot/P13296|https://www.uniprot.org/uniprot/P06804|https://www.uniprot.org/uniprot/P04924|https://www.uniprot.org/uniprot/P01375|https://www.uniprot.org/uniprot/O77764|https://www.uniprot.org/uniprot/O77510|https://www.uniprot.org/uniprot/O43647|https://www.uniprot.org/uniprot/O35853|https://www.uniprot.org/uniprot/O35734|https://www.uniprot.org/uniprot/O18779|https://www.uniprot.org/uniprot/A9QWR7|https://www.uniprot.org/uniprot/A5D9N8|https://www.uniprot.org/uniprot/A4IFT5|https://www.uniprot.org/uniprot/Q28339|https://www.uniprot.org/uniprot/Q28320|https://www.uniprot.org/uniprot/Q27978|https://www.uniprot.org/uniprot/Q1XHZ6|https://www.uniprot.org/uniprot/Q1WM27|https://www.uniprot.org/uniprot/Q1G1A2|https://www.uniprot.org/uniprot/Q19LH4|https://www.uniprot.org/uniprot/Q06599|https://www.uniprot.org/uniprot/Q006K5|https://www.uniprot.org/uniprot/P79374|https://www.uniprot.org/uniprot/P79337|https://www.uniprot.org/uniprot/P59695|https://www.uniprot.org/uniprot/P59694|https://www.uniprot.org/uniprot/P59693|https://www.uniprot.org/uniprot/P59684|https://www.uniprot.org/uniprot/P51743|https://www.uniprot.org/uniprot/P51742|https://www.uniprot.org/uniprot/P51435|https://www.uniprot.org/uniprot/P48094|https://www.uniprot.org/uniprot/P36939|https://www.uniprot.org/uniprot/P33620 |
LitCovid-sample-PD-IDO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T68 | 85-96 | http://purl.obolibrary.org/obo/IDO_0000608 | denotes | replication |
T69 | 112-127 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
T70 | 162-171 | http://purl.obolibrary.org/obo/IDO_0000559 | denotes | antiviral |
T71 | 522-526 | http://purl.obolibrary.org/obo/IDO_0000531 | denotes | host |
T72 | 638-642 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cell |
T73 | 679-689 | http://purl.obolibrary.org/obo/IDO_0000607 | denotes | production |
T74 | 742-747 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cells |
T75 | 754-759 | http://purl.obolibrary.org/obo/CL_0000000 | denotes | cells |
T76 | 822-829 | http://purl.obolibrary.org/obo/OGMS_0000031 | denotes | disease |
LitCovid-sample-PD-FMA
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T36 | 336-343 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T37 | 382-393 | Body_part | denotes | ganglioside | http://purl.org/sig/ont/fma/fma82816 |
T38 | 561-564 | Body_part | denotes | MHC | http://purl.org/sig/ont/fma/fma84079 |
T39 | 638-642 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T40 | 693-702 | Body_part | denotes | cytokines | http://purl.org/sig/ont/fma/fma84050 |
T41 | 742-747 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T42 | 754-759 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T43 | 923-930 | Body_part | denotes | protein | http://purl.org/sig/ont/fma/fma67257 |
T44 | 939-942 | Body_part | denotes | MHC | http://purl.org/sig/ont/fma/fma84079 |
T45 | 947-979 | Body_part | denotes | major histocompatibility complex | http://purl.org/sig/ont/fma/fma84079 |
T46 | 1063-1065 | Body_part | denotes | IL | http://purl.org/sig/ont/fma/fma86578 |
T47 | 1067-1078 | Body_part | denotes | interleukin | http://purl.org/sig/ont/fma/fma86578 |
LitCovid-sample-PD-GO-BP-0
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10 | 112-127 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
T11 | 410-425 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
T12 | 462-475 | http://purl.obolibrary.org/obo/GO_0045851 | denotes | acidification |
T13 | 493-496 | http://purl.obolibrary.org/obo/GO_0004707 | denotes | p38 |
T14 | 561-564 | http://purl.obolibrary.org/obo/GO_0046776 | denotes | MHC |
T15 | 652-661 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T16 | 899-903 | http://purl.obolibrary.org/obo/GO_0004707 | denotes | MAPK |
T17 | 939-942 | http://purl.obolibrary.org/obo/GO_0046776 | denotes | MHC |
T18 | 947-979 | http://purl.obolibrary.org/obo/GO_0046776 | denotes | major histocompatibility complex |
T19 | 1093-1101 | http://purl.obolibrary.org/obo/GO_0001906 | denotes | necrosis |
T20 | 1093-1101 | http://purl.obolibrary.org/obo/GO_0008219 | denotes | necrosis |
T21 | 1093-1101 | http://purl.obolibrary.org/obo/GO_0019835 | denotes | necrosis |
T22 | 1093-1101 | http://purl.obolibrary.org/obo/GO_0070265 | denotes | necrosis |
LitCovid-sample-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T61 | 204-212 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T62 | 800-808 | Disease | denotes | COVID-19 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T63 | 810-834 | Disease | denotes | coronavirus disease 2019 | http://purl.obolibrary.org/obo/MONDO_0100096 |
T64 | 1087-1092 | Disease | denotes | tumor | http://purl.obolibrary.org/obo/MONDO_0005070 |
LitCovid-sample-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T8 | 1087-1092 | Phenotype | denotes | tumor | http://purl.obolibrary.org/obo/HP_0002664 |
LitCovid-sample-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10 | 112-127 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
T11 | 410-425 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
T12 | 462-475 | http://purl.obolibrary.org/obo/GO_0045851 | denotes | acidification |
T13 | 561-564 | http://purl.obolibrary.org/obo/GO_0046776 | denotes | MHC |
T14 | 652-661 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T15 | 899-903 | http://purl.obolibrary.org/obo/GO_0004707 | denotes | MAPK |
T16 | 939-942 | http://purl.obolibrary.org/obo/GO_0046776 | denotes | MHC |
T17 | 947-979 | http://purl.obolibrary.org/obo/GO_0046776 | denotes | major histocompatibility complex |
T18 | 1093-1101 | http://purl.obolibrary.org/obo/GO_0070265 | denotes | necrosis |
T19 | 1093-1101 | http://purl.obolibrary.org/obo/GO_0019835 | denotes | necrosis |
T20 | 1093-1101 | http://purl.obolibrary.org/obo/GO_0008219 | denotes | necrosis |
T21 | 1093-1101 | http://purl.obolibrary.org/obo/GO_0001906 | denotes | necrosis |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T10 | 112-127 | http://purl.obolibrary.org/obo/GO_0006955 | denotes | immune response |
T11 | 410-425 | http://purl.obolibrary.org/obo/GO_0061025 | denotes | membrane fusion |
T12 | 462-475 | http://purl.obolibrary.org/obo/GO_0045851 | denotes | acidification |
T13 | 561-564 | http://purl.obolibrary.org/obo/GO_0046776 | denotes | MHC |
T14 | 652-661 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signaling |
T15 | 899-903 | http://purl.obolibrary.org/obo/GO_0004707 | denotes | MAPK |
T16 | 939-942 | http://purl.obolibrary.org/obo/GO_0046776 | denotes | MHC |
T17 | 947-979 | http://purl.obolibrary.org/obo/GO_0046776 | denotes | major histocompatibility complex |
T18 | 1093-1101 | http://purl.obolibrary.org/obo/GO_0070265 | denotes | necrosis |
T19 | 1093-1101 | http://purl.obolibrary.org/obo/GO_0019835 | denotes | necrosis |
T20 | 1093-1101 | http://purl.obolibrary.org/obo/GO_0008219 | denotes | necrosis |
T21 | 1093-1101 | http://purl.obolibrary.org/obo/GO_0001906 | denotes | necrosis |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
322 | 325-329 | Gene | denotes | ACE2 | Gene:59272 |
323 | 493-496 | Gene | denotes | p38 | Gene:1432 |
324 | 606-611 | Gene | denotes | CD154 | Gene:959 |
325 | 630-633 | Gene | denotes | CD4 | Gene:920 |
326 | 80-84 | Species | denotes | CoVs | Tax:11118 |
327 | 65-67 | Chemical | denotes | CQ | MESH:D002738 |
328 | 68-71 | Chemical | denotes | HCQ | MESH:D006886 |
329 | 204-212 | Disease | denotes | COVID-19 | MESH:C000657245 |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T68 | 0-9 | Sentence | denotes | Figure 1. |
T69 | 10-128 | Sentence | denotes | Schematic representation of the possible mechanisms of CQ/HCQ against CoVs replication and modulating immune response. |
T70 | 129-760 | Sentence | denotes | CQ/HCQ may synergistically exert antiviral and immunomodulatory effects on COVID-19 through multiple mechanisms including hindering the receptor recognition process by influencing the affinity of ACE2 and S protein, and the affinity for sialic acid and ganglioside; inhibiting the membrane fusion process by suppressing endolysosome acidification; suppressing the p38 activation and affecting host defense machinery, and preventing MHC class II expression (block expression of CD154 on the surface of CD4 + T cell) and TLR signaling and reducing the production of cytokines through inhibiting the activation of T cells and B cells. |
T71 | 761-1111 | Sentence | denotes | ACE2, angiotensin-converting enzyme 2; COVID-19, coronavirus disease 2019; CQ, chloroquine; HCQ, hydroxychloroquine; CoVs, coronaviruses; MAPK, mitogen-activated protein kinase; MHC-II, major histocompatibility complex class II; TLR, toll-like receptor; cGAS, cyclic GMP-AMP synthase; IFN, interferon; IL, interleukin; TNF-α, tumor necrosis factor-α. |
LitCovid-PD-HP
Id | Subject | Object | Predicate | Lexical cue | hp_id |
---|---|---|---|---|---|
T8 | 1087-1092 | Phenotype | denotes | tumor | http://purl.obolibrary.org/obo/HP_0002664 |