PMC:7435837 / 20007-20935
Annnotations
{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7435837","sourcedb":"PMC","sourceid":"7435837","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7435837","text":"The reader should be able to realize that the LbL technique presents numerous possibilities for the application of polysaccharides as antiviral surfaces. Firstly, the polysaccharides, especially GAGs are abundantly available. Secondly, they can recognize and interact with proteins via a range of intermolecular forces including electrostatic, hydrogen bonding, and hydrophobic bonding [112]. Thirdly, the polysaccharides are biological molecules and in the case of LbL applications, need minimal or no modification to perform their intended function. Fourthly, fairly low quantities of material need to be deposited to coat the substrates. Lastly, they are biocompatible, biodegradable, and most renewable sources of material. It is very apt to illustrate the chemical structures of the GAGs and some other selected polysaccharides at this point. Figure 4 shows the structures based on the official IUPAC recommendations [113].","tracks":[{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T216","span":{"begin":115,"end":130},"obj":"Body_part"},{"id":"T217","span":{"begin":167,"end":182},"obj":"Body_part"},{"id":"T218","span":{"begin":195,"end":199},"obj":"Body_part"},{"id":"T219","span":{"begin":273,"end":281},"obj":"Body_part"},{"id":"T220","span":{"begin":406,"end":421},"obj":"Body_part"},{"id":"T221","span":{"begin":788,"end":792},"obj":"Body_part"},{"id":"T222","span":{"begin":817,"end":832},"obj":"Body_part"}],"attributes":[{"id":"A216","pred":"fma_id","subj":"T216","obj":"http://purl.org/sig/ont/fma/fma82746"},{"id":"A217","pred":"fma_id","subj":"T217","obj":"http://purl.org/sig/ont/fma/fma82746"},{"id":"A218","pred":"fma_id","subj":"T218","obj":"http://purl.org/sig/ont/fma/fma63011"},{"id":"A219","pred":"fma_id","subj":"T219","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A220","pred":"fma_id","subj":"T220","obj":"http://purl.org/sig/ont/fma/fma82746"},{"id":"A221","pred":"fma_id","subj":"T221","obj":"http://purl.org/sig/ont/fma/fma63011"},{"id":"A222","pred":"fma_id","subj":"T222","obj":"http://purl.org/sig/ont/fma/fma82746"},{"subj":"T216","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T217","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T218","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T219","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T220","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T221","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T222","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T215","span":{"begin":286,"end":287},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"}],"attributes":[{"subj":"T215","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T293","span":{"begin":100,"end":111},"obj":"Chemical"},{"id":"T294","span":{"begin":115,"end":130},"obj":"Chemical"},{"id":"T295","span":{"begin":134,"end":143},"obj":"Chemical"},{"id":"T296","span":{"begin":167,"end":182},"obj":"Chemical"},{"id":"T297","span":{"begin":195,"end":199},"obj":"Chemical"},{"id":"T298","span":{"begin":273,"end":281},"obj":"Chemical"},{"id":"T299","span":{"begin":344,"end":352},"obj":"Chemical"},{"id":"T300","span":{"begin":406,"end":421},"obj":"Chemical"},{"id":"T301","span":{"begin":437,"end":446},"obj":"Chemical"},{"id":"T302","span":{"begin":788,"end":792},"obj":"Chemical"},{"id":"T303","span":{"begin":817,"end":832},"obj":"Chemical"}],"attributes":[{"id":"A293","pred":"chebi_id","subj":"T293","obj":"http://purl.obolibrary.org/obo/CHEBI_33232"},{"id":"A294","pred":"chebi_id","subj":"T294","obj":"http://purl.obolibrary.org/obo/CHEBI_18154"},{"id":"A295","pred":"chebi_id","subj":"T295","obj":"http://purl.obolibrary.org/obo/CHEBI_22587"},{"id":"A296","pred":"chebi_id","subj":"T296","obj":"http://purl.obolibrary.org/obo/CHEBI_18154"},{"id":"A297","pred":"chebi_id","subj":"T297","obj":"http://purl.obolibrary.org/obo/CHEBI_18085"},{"id":"A298","pred":"chebi_id","subj":"T298","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A299","pred":"chebi_id","subj":"T299","obj":"http://purl.obolibrary.org/obo/CHEBI_49637"},{"id":"A300","pred":"chebi_id","subj":"T300","obj":"http://purl.obolibrary.org/obo/CHEBI_18154"},{"id":"A301","pred":"chebi_id","subj":"T301","obj":"http://purl.obolibrary.org/obo/CHEBI_25367"},{"id":"A302","pred":"chebi_id","subj":"T302","obj":"http://purl.obolibrary.org/obo/CHEBI_18085"},{"id":"A303","pred":"chebi_id","subj":"T303","obj":"http://purl.obolibrary.org/obo/CHEBI_18154"},{"subj":"T293","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T294","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T295","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T296","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T297","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T298","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T299","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T300","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T301","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T302","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T303","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"476","span":{"begin":115,"end":130},"obj":"Chemical"},{"id":"477","span":{"begin":167,"end":182},"obj":"Chemical"},{"id":"478","span":{"begin":344,"end":352},"obj":"Chemical"},{"id":"479","span":{"begin":406,"end":421},"obj":"Chemical"},{"id":"480","span":{"begin":466,"end":469},"obj":"Chemical"},{"id":"481","span":{"begin":817,"end":832},"obj":"Chemical"}],"attributes":[{"id":"A476","pred":"tao:has_database_id","subj":"476","obj":"MESH:D011134"},{"id":"A477","pred":"tao:has_database_id","subj":"477","obj":"MESH:D011134"},{"id":"A478","pred":"tao:has_database_id","subj":"478","obj":"MESH:D006859"},{"id":"A479","pred":"tao:has_database_id","subj":"479","obj":"MESH:D011134"},{"id":"A481","pred":"tao:has_database_id","subj":"481","obj":"MESH:D011134"},{"subj":"476","pred":"source","obj":"LitCovid-PubTator"},{"subj":"477","pred":"source","obj":"LitCovid-PubTator"},{"subj":"478","pred":"source","obj":"LitCovid-PubTator"},{"subj":"479","pred":"source","obj":"LitCovid-PubTator"},{"subj":"480","pred":"source","obj":"LitCovid-PubTator"},{"subj":"481","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T152","span":{"begin":0,"end":153},"obj":"Sentence"},{"id":"T153","span":{"begin":154,"end":225},"obj":"Sentence"},{"id":"T154","span":{"begin":226,"end":392},"obj":"Sentence"},{"id":"T155","span":{"begin":393,"end":551},"obj":"Sentence"},{"id":"T156","span":{"begin":552,"end":640},"obj":"Sentence"},{"id":"T157","span":{"begin":641,"end":727},"obj":"Sentence"},{"id":"T158","span":{"begin":728,"end":847},"obj":"Sentence"},{"id":"T159","span":{"begin":848,"end":928},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T152","pred":"source","obj":"LitCovid-sentences"},{"subj":"T153","pred":"source","obj":"LitCovid-sentences"},{"subj":"T154","pred":"source","obj":"LitCovid-sentences"},{"subj":"T155","pred":"source","obj":"LitCovid-sentences"},{"subj":"T156","pred":"source","obj":"LitCovid-sentences"},{"subj":"T157","pred":"source","obj":"LitCovid-sentences"},{"subj":"T158","pred":"source","obj":"LitCovid-sentences"},{"subj":"T159","pred":"source","obj":"LitCovid-sentences"}]},{"project":"2_test","denotations":[{"id":"32731428-21545980-71421320","span":{"begin":387,"end":390},"obj":"21545980"},{"id":"32731428-3743566-71421321","span":{"begin":923,"end":926},"obj":"3743566"}],"attributes":[{"subj":"32731428-21545980-71421320","pred":"source","obj":"2_test"},{"subj":"32731428-3743566-71421321","pred":"source","obj":"2_test"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PD-FMA-UBERON","color":"#c1ec93","default":true},{"id":"LitCovid-PD-CLO","color":"#ec93db"},{"id":"LitCovid-PD-CHEBI","color":"#93ece3"},{"id":"LitCovid-PubTator","color":"#ecc993"},{"id":"LitCovid-sentences","color":"#af93ec"},{"id":"2_test","color":"#93ec95"}]}]}}