PMC:7402624 / 1975-2608 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T8","span":{"begin":0,"end":12},"obj":"Body_part"},{"id":"T9","span":{"begin":50,"end":55},"obj":"Body_part"},{"id":"T10","span":{"begin":184,"end":188},"obj":"Body_part"},{"id":"T11","span":{"begin":225,"end":229},"obj":"Body_part"},{"id":"T12","span":{"begin":267,"end":271},"obj":"Body_part"},{"id":"T13","span":{"begin":464,"end":467},"obj":"Body_part"},{"id":"T14","span":{"begin":484,"end":489},"obj":"Body_part"},{"id":"T15","span":{"begin":497,"end":502},"obj":"Body_part"},{"id":"T16","span":{"begin":556,"end":574},"obj":"Body_part"},{"id":"T17","span":{"begin":569,"end":574},"obj":"Body_part"},{"id":"T18","span":{"begin":590,"end":595},"obj":"Body_part"},{"id":"T19","span":{"begin":606,"end":610},"obj":"Body_part"}],"attributes":[{"id":"A8","pred":"fma_id","subj":"T8","obj":"http://purl.org/sig/ont/fma/fma76577"},{"id":"A9","pred":"fma_id","subj":"T9","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A10","pred":"fma_id","subj":"T10","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A11","pred":"fma_id","subj":"T11","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A12","pred":"fma_id","subj":"T12","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A13","pred":"fma_id","subj":"T13","obj":"http://purl.org/sig/ont/fma/fma20935"},{"id":"A14","pred":"fma_id","subj":"T14","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A15","pred":"fma_id","subj":"T15","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A16","pred":"fma_id","subj":"T16","obj":"http://purl.org/sig/ont/fma/fma84070"},{"id":"A17","pred":"fma_id","subj":"T17","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A18","pred":"fma_id","subj":"T18","obj":"http://purl.org/sig/ont/fma/fma68646"},{"id":"A19","pred":"fma_id","subj":"T19","obj":"http://purl.org/sig/ont/fma/fma68646"}],"text":"compartments (5) but the characteristics of these cells and their role in infection or pathogenesis remain unclear. Recovered subjects more often have evidence of virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or"}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T1","span":{"begin":497,"end":502},"obj":"Body_part"}],"attributes":[{"id":"A1","pred":"uberon_id","subj":"T1","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"}],"text":"compartments (5) but the characteristics of these cells and their role in infection or pathogenesis remain unclear. Recovered subjects more often have evidence of virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or"}

{"project":"LitCovid-PubTator","denotations":[{"id":"63","span":{"begin":178,"end":181},"obj":"Gene"},{"id":"64","span":{"begin":261,"end":264},"obj":"Gene"},{"id":"65","span":{"begin":452,"end":456},"obj":"Gene"},{"id":"66","span":{"begin":461,"end":467},"obj":"Gene"},{"id":"67","span":{"begin":478,"end":481},"obj":"Gene"},{"id":"68","span":{"begin":219,"end":222},"obj":"Gene"},{"id":"69","span":{"begin":291,"end":304},"obj":"Species"},{"id":"70","span":{"begin":362,"end":371},"obj":"Species"},{"id":"73","span":{"begin":74,"end":83},"obj":"Disease"}],"attributes":[{"id":"A63","pred":"tao:has_database_id","subj":"63","obj":"Gene:920"},{"id":"A64","pred":"tao:has_database_id","subj":"64","obj":"Gene:920"},{"id":"A65","pred":"tao:has_database_id","subj":"65","obj":"Gene:3569"},{"id":"A66","pred":"tao:has_database_id","subj":"66","obj":"Gene:1437"},{"id":"A67","pred":"tao:has_database_id","subj":"67","obj":"Gene:920"},{"id":"A68","pred":"tao:has_database_id","subj":"68","obj":"Gene:925"},{"id":"A69","pred":"tao:has_database_id","subj":"69","obj":"Tax:11118"},{"id":"A70","pred":"tao:has_database_id","subj":"70","obj":"Tax:2697049"},{"id":"A73","pred":"tao:has_database_id","subj":"73","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"compartments (5) but the characteristics of these cells and their role in infection or pathogenesis remain unclear. Recovered subjects more often have evidence of virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or"}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T19","span":{"begin":74,"end":83},"obj":"Disease"},{"id":"T20","span":{"begin":362,"end":366},"obj":"Disease"}],"attributes":[{"id":"A19","pred":"mondo_id","subj":"T19","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A20","pred":"mondo_id","subj":"T20","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"compartments (5) but the characteristics of these cells and their role in infection or pathogenesis remain unclear. Recovered subjects more often have evidence of virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or"}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T17","span":{"begin":50,"end":55},"obj":"http://purl.obolibrary.org/obo/GO_0005623"},{"id":"T18","span":{"begin":163,"end":168},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T19","span":{"begin":178,"end":181},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T20","span":{"begin":182,"end":188},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T21","span":{"begin":204,"end":209},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T22","span":{"begin":219,"end":222},"obj":"http://purl.obolibrary.org/obo/CLO_0053438"},{"id":"T23","span":{"begin":223,"end":229},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T24","span":{"begin":261,"end":264},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T25","span":{"begin":265,"end":271},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T26","span":{"begin":323,"end":324},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T27","span":{"begin":478,"end":481},"obj":"http://purl.obolibrary.org/obo/PR_000001004"},{"id":"T28","span":{"begin":482,"end":489},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T29","span":{"begin":497,"end":502},"obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"T30","span":{"begin":497,"end":502},"obj":"http://www.ebi.ac.uk/efo/EFO_0000296"},{"id":"T31","span":{"begin":556,"end":574},"obj":"http://purl.obolibrary.org/obo/CL_0000815"},{"id":"T32","span":{"begin":576,"end":580},"obj":"http://purl.obolibrary.org/obo/CL_0000792"},{"id":"T33","span":{"begin":588,"end":595},"obj":"http://purl.obolibrary.org/obo/CL_0000084"},{"id":"T34","span":{"begin":599,"end":601},"obj":"http://purl.obolibrary.org/obo/CLO_0053733"},{"id":"T35","span":{"begin":604,"end":610},"obj":"http://purl.obolibrary.org/obo/CL_0000084"}],"text":"compartments (5) but the characteristics of these cells and their role in infection or pathogenesis remain unclear. Recovered subjects more often have evidence of virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or"}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T5","span":{"begin":452,"end":454},"obj":"Chemical"},{"id":"T7","span":{"begin":461,"end":463},"obj":"Chemical"}],"attributes":[{"id":"A5","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_63895"},{"id":"A6","pred":"chebi_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/CHEBI_74072"},{"id":"A7","pred":"chebi_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/CHEBI_74120"}],"text":"compartments (5) but the characteristics of these cells and their role in infection or pathogenesis remain unclear. Recovered subjects more often have evidence of virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or"}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T12","span":{"begin":87,"end":99},"obj":"http://purl.obolibrary.org/obo/GO_0009405"},{"id":"T13","span":{"begin":386,"end":408},"obj":"http://purl.obolibrary.org/obo/GO_0006954"}],"text":"compartments (5) but the characteristics of these cells and their role in infection or pathogenesis remain unclear. Recovered subjects more often have evidence of virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or"}

{"project":"LitCovid-sentences","denotations":[{"id":"T18","span":{"begin":116,"end":385},"obj":"Sentence"},{"id":"T19","span":{"begin":386,"end":603},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"compartments (5) but the characteristics of these cells and their role in infection or pathogenesis remain unclear. Recovered subjects more often have evidence of virus-specific CD4 T cell responses than virus-specific CD8 T cell responses, though pre-existing CD4 T cell responses to other coronaviruses also are found in a subset of subjects in the absence of SARS-CoV2 exposure (6). Inflammatory responses have been reported, including increases in IL-6- or GM-CSF-producing CD4 T cells in the blood (7) or decreases in immunoregulatory subsets such as regulatory T cells (Treg) or ɣδ T cells (8–11). T cell exhaustion (12, 13) or"}