PMC:7373848 / 17111-18105
Annnotations
LitCovid-PD-FMA-UBERON
Id | Subject | Object | Predicate | Lexical cue | fma_id |
---|---|---|---|---|---|
T277 | 20-29 | Body_part | denotes | platelets | http://purl.org/sig/ont/fma/fma62851 |
T278 | 96-105 | Body_part | denotes | platelets | http://purl.org/sig/ont/fma/fma62851 |
T279 | 123-134 | Body_part | denotes | endothelium | http://purl.org/sig/ont/fma/fma63916 |
T280 | 200-210 | Body_part | denotes | P-selectin | http://purl.org/sig/ont/fma/fma62933 |
T281 | 268-288 | Body_part | denotes | Weibel-Palade bodies | http://purl.org/sig/ont/fma/fma63176 |
T282 | 297-312 | Body_part | denotes | plasma membrane | http://purl.org/sig/ont/fma/fma63841 |
T283 | 331-340 | Body_part | denotes | platelets | http://purl.org/sig/ont/fma/fma62851 |
T284 | 365-381 | Body_part | denotes | endothelial cell | http://purl.org/sig/ont/fma/fma66772 |
T285 | 377-381 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
T286 | 382-392 | Body_part | denotes | P-selectin | http://purl.org/sig/ont/fma/fma62933 |
T287 | 411-420 | Body_part | denotes | platelets | http://purl.org/sig/ont/fma/fma62851 |
T288 | 431-448 | Body_part | denotes | endothelial cells | http://purl.org/sig/ont/fma/fma66772 |
T289 | 443-448 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
T290 | 460-468 | Body_part | denotes | platelet | http://purl.org/sig/ont/fma/fma62851 |
T291 | 469-477 | Body_part | denotes | integrin | http://purl.org/sig/ont/fma/fma67222 |
T292 | 612-623 | Body_part | denotes | fibronectin | http://purl.org/sig/ont/fma/fma67311 |
T293 | 629-650 | Body_part | denotes | von Willebrand factor | http://purl.org/sig/ont/fma/fma81101 |
T294 | 676-685 | Body_part | denotes | cytokines | http://purl.org/sig/ont/fma/fma84050 |
T295 | 694-702 | Body_part | denotes | platelet | http://purl.org/sig/ont/fma/fma62851 |
T296 | 713-722 | Body_part | denotes | Platelets | http://purl.org/sig/ont/fma/fma62851 |
T297 | 899-908 | Body_part | denotes | platelets | http://purl.org/sig/ont/fma/fma62851 |
LitCovid-PD-UBERON
Id | Subject | Object | Predicate | Lexical cue | uberon_id |
---|---|---|---|---|---|
T89 | 123-134 | Body_part | denotes | endothelium | http://purl.obolibrary.org/obo/UBERON_0001986 |
LitCovid-PubTator
Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
---|---|---|---|---|---|
283 | 200-210 | Gene | denotes | P-selectin | Gene:6403 |
284 | 314-319 | Gene | denotes | GPIbα | Gene:2811 |
285 | 382-392 | Gene | denotes | P-selectin | Gene:6403 |
286 | 600-610 | Gene | denotes | fibrinogen | Gene:2244 |
287 | 612-623 | Gene | denotes | fibronectin | Gene:2335 |
288 | 629-650 | Gene | denotes | von Willebrand factor | Gene:7450 |
289 | 652-655 | Gene | denotes | VWF | Gene:7450 |
291 | 842-854 | Disease | denotes | inflammation | MESH:D007249 |
LitCovid-PD-MONDO
Id | Subject | Object | Predicate | Lexical cue | mondo_id |
---|---|---|---|---|---|
T61 | 842-854 | Disease | denotes | inflammation | http://purl.obolibrary.org/obo/MONDO_0021166 |
LitCovid-PD-CLO
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T286 | 123-134 | http://purl.obolibrary.org/obo/UBERON_0001986 | denotes | endothelium |
T287 | 139-140 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
T288 | 237-246 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membranes |
T289 | 297-303 | http://purl.obolibrary.org/obo/UBERON_0001969 | denotes | plasma |
T290 | 304-312 | http://purl.obolibrary.org/obo/UBERON_0000158 | denotes | membrane |
T291 | 365-381 | http://purl.obolibrary.org/obo/CL_0000115 | denotes | endothelial cell |
T292 | 431-448 | http://purl.obolibrary.org/obo/CL_0000115 | denotes | endothelial cells |
T293 | 612-623 | http://purl.obolibrary.org/obo/PR_000007581 | denotes | fibronectin |
T294 | 773-775 | http://purl.obolibrary.org/obo/CLO_0001302 | denotes | 34 |
T295 | 856-858 | http://purl.obolibrary.org/obo/CLO_0001000 | denotes | 35 |
T296 | 990-992 | http://purl.obolibrary.org/obo/CLO_0001313 | denotes | 36 |
LitCovid-PD-CHEBI
Id | Subject | Object | Predicate | Lexical cue | chebi_id |
---|---|---|---|---|---|
T105 | 559-567 | Chemical | denotes | molecule | http://purl.obolibrary.org/obo/CHEBI_25367 |
LitCovid-PD-GO-BP
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T71 | 53-59 | http://purl.obolibrary.org/obo/GO_0040007 | denotes | growth |
T72 | 250-257 | http://purl.obolibrary.org/obo/GO_0051235 | denotes | storage |
T73 | 842-854 | http://purl.obolibrary.org/obo/GO_0006954 | denotes | inflammation |
T74 | 944-953 | http://purl.obolibrary.org/obo/GO_0009058 | denotes | synthesis |
LitCovid-sentences
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T116 | 0-70 | Sentence | denotes | The contribution of platelets to vascular integrity, growth and repair |
T117 | 71-162 | Sentence | denotes | The interactions between platelets and the vascular endothelium are a tightly orchestrated. |
T118 | 163-313 | Sentence | denotes | In response to inflammatory stimuli, P-selectin rapidly translocates from membranes of storage granules (Weibel-Palade bodies) to the plasma membrane. |
T119 | 314-393 | Sentence | denotes | GPIbα present on platelets recognizes and binds to endothelial cell P-selectin. |
T120 | 394-570 | Sentence | denotes | Firm adhesion of platelets to intact endothelial cells depends on platelet integrin αIIbβ3 bridging to endothelial receptors such as αVβ3 and intercellular adhesion molecule-1. |
T121 | 571-662 | Sentence | denotes | Ligands for bridging include fibrinogen, fibronectin, and von Willebrand factor (VWF) [33]. |
T122 | 663-712 | Sentence | denotes | Inflammatory cytokines augment platelet adhesion. |
T123 | 713-860 | Sentence | denotes | Platelets are essential for maintaining vascular integrity [34] and endothelial barrier function, particularly in the setting of inflammation [35]. |
T124 | 861-994 | Sentence | denotes | In addition to physical interactions, platelets promote vascular integrity through synthesis and release of bioactive mediators [36]. |
LitCovid-PMC-OGER-BB
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
T576 | 20-29 | CL:0000233 | denotes | platelets |
T577 | 96-105 | CL:0000233 | denotes | platelets |
T578 | 123-134 | UBERON:0001986 | denotes | endothelium |
T579 | 200-210 | PR:000001432 | denotes | P-selectin |
T580 | 237-246 | GO:0016020 | denotes | membranes |
T581 | 250-257 | GO:0000322 | denotes | storage |
T582 | 258-266 | GO:0009542 | denotes | granules |
T583 | 297-312 | GO:0005886 | denotes | plasma membrane |
T584 | 331-340 | CL:0000233 | denotes | platelets |
T585 | 365-376 | UBERON:0001986;CL:0000115 | denotes | endothelial |
T586 | 377-381 | CL:0000115 | denotes | cell |
T587 | 382-392 | PR:000001432 | denotes | P-selectin |
T588 | 411-420 | CL:0000233 | denotes | platelets |
T589 | 431-442 | UBERON:0001986;CL:0000115 | denotes | endothelial |
T590 | 443-448 | CL:0000115 | denotes | cells |
T591 | 460-468 | CL:0000233 | denotes | platelet |
T592 | 469-484 | GO:0034683 | denotes | integrin αIIbβ3 |
T593 | 485-493 | GO:0030674 | denotes | bridging |
T594 | 497-508 | UBERON:0001986 | denotes | endothelial |
T595 | 527-531 | GO:0034683 | denotes | αVβ3 |
T596 | 536-558 | PR:000001467 | denotes | intercellular adhesion |
T597 | 559-567 | PR:000001467;CHEBI:36357;CHEBI:36357 | denotes | molecule |
T598 | 583-591 | GO:0030674 | denotes | bridging |
T599 | 600-610 | GO:0005577 | denotes | fibrinogen |
T600 | 612-623 | PR:000007581 | denotes | fibronectin |
T601 | 629-650 | PR:000017364 | denotes | von Willebrand factor |
T602 | 652-655 | PR:000017364 | denotes | VWF |
T603 | 694-702 | CL:0000233 | denotes | platelet |
T604 | 713-722 | CL:0000233 | denotes | Platelets |
T605 | 781-792 | UBERON:0001986 | denotes | endothelial |
T606 | 899-908 | CL:0000233 | denotes | platelets |
T607 | 969-978 | CHEBI:15956;CHEBI:15956 | denotes | bioactive |
T608 | 979-988 | CHEBI:67079;CHEBI:67079 | denotes | mediators |
2_test
Id | Subject | Object | Predicate | Lexical cue |
---|---|---|---|---|
32700024-11071623-64991470 | 658-660 | 11071623 | denotes | 33 |
32700024-26749528-64991471 | 773-775 | 26749528 | denotes | 34 |
32700024-18256319-64991472 | 856-858 | 18256319 | denotes | 35 |
32700024-27582371-64991473 | 990-992 | 27582371 | denotes | 36 |