PMC:7354481 / 40967-41677
Annnotations
LitCovid-PD-FMA-UBERON
| Id | Subject | Object | Predicate | Lexical cue | fma_id |
|---|---|---|---|---|---|
| T278 | 154-158 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T279 | 185-189 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T280 | 260-276 | Body_part | denotes | epithelial cells | http://purl.org/sig/ont/fma/fma66768 |
| T281 | 271-276 | Body_part | denotes | cells | http://purl.org/sig/ont/fma/fma68646 |
| T282 | 413-417 | Body_part | denotes | cell | http://purl.org/sig/ont/fma/fma68646 |
| T283 | 508-512 | Body_part | denotes | lung | http://purl.org/sig/ont/fma/fma7195 |
| T284 | 616-623 | Body_part | denotes | genomes | http://purl.org/sig/ont/fma/fma84116 |
LitCovid-PD-UBERON
| Id | Subject | Object | Predicate | Lexical cue | uberon_id |
|---|---|---|---|---|---|
| T56 | 154-158 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T57 | 185-189 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
| T58 | 508-512 | Body_part | denotes | lung | http://purl.obolibrary.org/obo/UBERON_0002048 |
LitCovid-PD-MONDO
| Id | Subject | Object | Predicate | Lexical cue | mondo_id |
|---|---|---|---|---|---|
| T247 | 179-196 | Disease | denotes | acute lung injury | http://purl.obolibrary.org/obo/MONDO_0006502|http://purl.obolibrary.org/obo/MONDO_0015796 |
| T249 | 190-196 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
| T250 | 201-205 | Disease | denotes | COPD | http://purl.obolibrary.org/obo/MONDO_0005002 |
| T251 | 513-519 | Disease | denotes | injury | http://purl.obolibrary.org/obo/MONDO_0021178 |
LitCovid-PD-CLO
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T459 | 22-25 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T460 | 66-69 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T461 | 154-158 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T462 | 154-158 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T463 | 185-189 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T464 | 185-189 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T465 | 207-208 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | A |
| T466 | 244-249 | http://purl.obolibrary.org/obo/NCBITaxon_9606 | denotes | human |
| T467 | 260-270 | http://purl.obolibrary.org/obo/CL_0000066 | denotes | epithelial |
| T468 | 271-276 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cells |
| T469 | 306-309 | http://purl.obolibrary.org/obo/CLO_0051582 | denotes | has |
| T470 | 413-417 | http://purl.obolibrary.org/obo/GO_0005623 | denotes | cell |
| T471 | 418-428 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signalling |
| T472 | 453-463 | http://purl.obolibrary.org/obo/SO_0000418 | denotes | signalling |
| T473 | 508-512 | http://purl.obolibrary.org/obo/UBERON_0002048 | denotes | lung |
| T474 | 508-512 | http://www.ebi.ac.uk/efo/EFO_0000934 | denotes | lung |
| T475 | 694-695 | http://purl.obolibrary.org/obo/CLO_0001020 | denotes | a |
LitCovid-PD-HP
| Id | Subject | Object | Predicate | Lexical cue | hp_id |
|---|---|---|---|---|---|
| T73 | 42-58 | Phenotype | denotes | oxidative stress | http://purl.obolibrary.org/obo/HP_0025464 |
| T74 | 179-196 | Phenotype | denotes | acute lung injury | http://www.orpha.net/ORDO/Orphanet_178320 |
| T75 | 201-205 | Phenotype | denotes | COPD | http://purl.obolibrary.org/obo/HP_0006510 |
| T76 | 297-304 | Phenotype | denotes | hypoxia | http://purl.obolibrary.org/obo/HP_0012418 |
| T77 | 356-363 | Phenotype | denotes | hypoxia | http://purl.obolibrary.org/obo/HP_0012418 |
LitCovid-PD-GO-BP
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T151 | 418-437 | http://purl.obolibrary.org/obo/GO_0007165 | denotes | signalling pathways |
| T152 | 418-428 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signalling |
| T153 | 453-463 | http://purl.obolibrary.org/obo/GO_0023052 | denotes | signalling |
LitCovid-sentences
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| T269 | 0-18 | Sentence | denotes | 4.1.6. miR-3691-3p |
| T270 | 19-206 | Sentence | denotes | It has been shown that oxidative stress, which has detrimental effects on intercellular communication, plays an important role in many lung pathologies such as acute lung injury and COPD. |
| T271 | 207-370 | Sentence | denotes | A proteomic profile of exosomes from human bronchial epithelial cells, under normoxia and hypoxia, has reported reduced expression of miR-3691-3p in hypoxia [100]. |
| T272 | 371-531 | Sentence | denotes | Interestingly, miR3691-3p targets several cell signalling pathways, such as TGF-β signalling, FGF2 and also VCAM1, which is relevant for lung injury and repair. |
| T273 | 532-710 | Sentence | denotes | In the current study, we have also identified that miR3691-3p exists in four of the genomes, which we have extensively studied here, and therefore it seems to be a conserved miR. |
2_test
| Id | Subject | Object | Predicate | Lexical cue |
|---|---|---|---|---|
| 32512929-19934357-144200780 | 365-368 | 19934357 | denotes | 100 |
LitCovid-PubTator
| Id | Subject | Object | Predicate | Lexical cue | tao:has_database_id |
|---|---|---|---|---|---|
| 1005 | 386-393 | Gene | denotes | miR3691 | Gene:100500900 |
| 1006 | 447-452 | Gene | denotes | TGF-β | Gene:7039 |
| 1007 | 465-469 | Gene | denotes | FGF2 | Gene:2247 |
| 1008 | 479-484 | Gene | denotes | VCAM1 | Gene:7412 |
| 1009 | 583-590 | Gene | denotes | miR3691 | Gene:100500900 |
| 1010 | 244-249 | Species | denotes | human | Tax:9606 |
| 1011 | 179-196 | Disease | denotes | acute lung injury | MESH:D055371 |
| 1012 | 201-205 | Disease | denotes | COPD | MESH:D029424 |
| 1013 | 297-304 | Disease | denotes | hypoxia | MESH:D000860 |
| 1014 | 356-363 | Disease | denotes | hypoxia | MESH:D000860 |
| 1015 | 508-519 | Disease | denotes | lung injury | MESH:D055370 |