PMC:7352545 / 82498-86766 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7352545","sourcedb":"PMC","sourceid":"7352545","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7352545","text":"Acknowledgments\nThis study was in part supported by a grant (NRF-2018R1D1A1A09081927 to CHK) of the Basic Science Research Program through National Research Foundation (NRF).\n\nAuthor Contributions\nConceptualization, C.-H.K.; writing—original draft preparation, C.-H.K.; writing, review and editing, C.-H.K. All authors have read and agreed to the published version of the manuscript.\n\nFunding\nFunded by the Ministry of Education, Science and Technology (MEST), Korea.\n\nConflicts of Interest\nThe author declares no conflicts of interest. Abbreviations\nHE hemagglutinin-esterase\nCOVID-19 coronavirus disease 2019\nSA sialic acid\nSARS-CoV severe acute respiratory syndrome-related coronavirus\nMERS-V Middle East respiratory syndrome virus\nRSV respiratory syncytial virus\nWHO World Health Organization\n2019-nCoV 2019-Novel Coronavirus\nGIT gastrointestinal track\nRDE receptor-destroying enzyme\nLRI ligand–receptor interaction\nLCI lectin–carbohydrate interaction\nLGI lectin–glycan interaction\nLSI lectin–sphingolipid interaction\nPGI protein–glycan interaction\nPCI protein–carbohydrate interaction\nPPI protein–protein interaction\nNeuC neuraminic acid\nNeuAc N-acetyl neuraminic acid\nNeuGc N-glycolyl neuraminic acid\nST sialyltransferase\nICTV International Committee on Taxonomy of Viruses\nHCoV human CoV\nORF open reading frame\nRdRp RNA-dependent RNA polymerase\nE envelope\nN nucleocapsid\nS spike glycoprotein\nM membrane matrix glycoprotein\nER endoplasmic reticulum\nERGIC endoplasmic reticulum-Golgi intermediate compartment\nNsp nonstructural protein\nRTC replicase–transcriptase complex\nTM transmembrane\nADRP ADP-ribose-1′-phosphatase\nPLpro papain-like protease\nMTase methyltransferase\nNTD N-terminal domain\nCTD C-terminal domain\nRBD receptor-binding domain\nssRNA single stranded RNA\nGSK3 glycogen synthase kinase 3\nhnRNP A1 heterogeneous nuclear ribonucleoprotein A1\nVLP virus-like particle\nNA neuraminidase\nNDV Newcastle disease\nNeu5Ac N-acetylneuraminic acid\nNeu5:9Ac2 9-O-acetyl-N-acetylneuraminic acid\nCasD1 Cas1 domain containing 1\nISAV infectious salmon anemia virus\nFH factor H\nNeu5Ac9NAc 9-acetamido-9-deoxy-N-acetylneuraminic acid\nHEF HE fusion protein\nNeu5:9Ac2 5-N-acetyl-9-O-NeuAc\nBCoV bovine CoV\nRBC red blood cell\nCRD carbohydrate-recognizing domain\nGBD glycan-binding domain\nMHV murine hepatitis virus\nCEACAM carcinoembryonic antigen cell adhesion molecule 1a\n9-O–AC-SA 9-O-acetylated SA\nPHEV porcine hemagglutinating encephalomyelitis virus\nRCoV rat CoV\nTGEV transmissible gastroenteritis coronavirus\nIBV infectious bronchitis virus\npAPN porcine aminopeptidase N\nMGP mucin-like glycoprotein\npNPA p-nitrophenyl acetate\nSLeX sialyl-LewisX\nα2:3-SlacNAc α2,3-sialyl-N-acetyl-lactosamine\nDPP4 dipeptidyl peptidase 4\nGRP78 membrane-associated 78-kDa glucose-regulated protein\nACE2 angiotensin-converting enzyme 2\nhAPN human APN\nMHC-I major histocompatibility complex class I\nDC-SIGN dendritic cells-specific intercellular adhesion molecule-3-grabbing nonintegrin\nHSPG heparan sulfate proteoglycan\nHSPA5 heat shock protein A5\nRAS renin-angiotensin system\nAng I angiotensin I\nAT1R Ang II receptor type 1\nGPCR G protein-coupled receptor\nADAM A disintegrin and metallopeptidase domain\nTACE TNF-α-converting enzyme\nTMPRSS transmembrane protease serine\nTTSP type II TM Ser protease\nPAR-2 protease activated receptor 2\nMMP matrix metalloproteinase\nHGF hepatocyte growth factor\nHAT human airway trypsin-like protease\nMSPL serine 13\nBHH bromhexine hydrochloride\nDPP4 dipeptidyl peptidase-4\nBiP immunoglobulin protein\nUPR unfolded protein response\nATF6 activating transcription factor 6\nIRE1 inositol-requiring enzyme 1\nPERK protein kinase RNA (PKR)-like ER kinase\nSBD substrate-binding domain\nPEDV porcine epidemic diarrhea coronavirus virus\nFIPV feline infectious peritonitis virus\nFeCV feline enteric virus\nGAG glycosaminoglycan\nGlcAT-II glucuronosyltransferase\nGlcNAcT-II N-acetylglucosaminyltransferase II\nNGS new generation sequencing\nRBM receptor-binding motif\n3CLpro 3-chymotrypsin-like protease\nCLQ chloroquine\nCLQ-OH hydroxychloroquine\nGBS ganglioside-binding site\nGBD ganglioside-binding domain\nWEF World Economic Forum\nVODAN Virus Outbreak Data 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