PMC:7352545 / 10666-11352 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T59","span":{"begin":81,"end":84},"obj":"Body_part"},{"id":"T60","span":{"begin":85,"end":91},"obj":"Body_part"},{"id":"T61","span":{"begin":127,"end":131},"obj":"Body_part"},{"id":"T62","span":{"begin":181,"end":184},"obj":"Body_part"},{"id":"T63","span":{"begin":185,"end":192},"obj":"Body_part"},{"id":"T64","span":{"begin":333,"end":341},"obj":"Body_part"},{"id":"T65","span":{"begin":358,"end":364},"obj":"Body_part"},{"id":"T66","span":{"begin":406,"end":417},"obj":"Body_part"},{"id":"T67","span":{"begin":518,"end":524},"obj":"Body_part"},{"id":"T68","span":{"begin":552,"end":556},"obj":"Body_part"},{"id":"T69","span":{"begin":583,"end":586},"obj":"Body_part"},{"id":"T70","span":{"begin":621,"end":624},"obj":"Body_part"},{"id":"T71","span":{"begin":639,"end":642},"obj":"Body_part"},{"id":"T72","span":{"begin":653,"end":656},"obj":"Body_part"}],"attributes":[{"id":"A59","pred":"fma_id","subj":"T59","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A60","pred":"fma_id","subj":"T60","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A61","pred":"fma_id","subj":"T61","obj":"http://purl.org/sig/ont/fma/fma67122"},{"id":"A62","pred":"fma_id","subj":"T62","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A63","pred":"fma_id","subj":"T63","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A64","pred":"fma_id","subj":"T64","obj":"http://purl.org/sig/ont/fma/fma67257"},{"id":"A65","pred":"fma_id","subj":"T65","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A66","pred":"fma_id","subj":"T66","obj":"http://purl.org/sig/ont/fma/fma82739"},{"id":"A67","pred":"fma_id","subj":"T67","obj":"http://purl.org/sig/ont/fma/fma84116"},{"id":"A68","pred":"fma_id","subj":"T68","obj":"http://purl.org/sig/ont/fma/fma67122"},{"id":"A69","pred":"fma_id","subj":"T69","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A70","pred":"fma_id","subj":"T70","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A71","pred":"fma_id","subj":"T71","obj":"http://purl.org/sig/ont/fma/fma67095"},{"id":"A72","pred":"fma_id","subj":"T72","obj":"http://purl.org/sig/ont/fma/fma67095"}],"text":"CoVs are 60–140 nm in size and are enveloped (+) ssRNA viruses, which feature an RNA genome, directly available to function as mRNA and thus result in rapid infection. CoVs exhibit RNA genomes of 28–32 kb, comprised of two large overlapping open reading frames (ORFs), which encode the virus replicase (transcriptase) and structural proteins. The SARS-CoV-2 genome is 29,891 bp in size, which encodes 9860 amino acids. The ssRNA are capped and tailed with a 5′-capping structure and 3′-poly A tail at the termini. The genome is the same sense as virus mRNA indicating that the viral RNA is translated through its own (+) RNA to synthesize RNA dependent RNA polymerase (RdRp; PDB: 6M71)."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T4","span":{"begin":493,"end":497},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/UBERON_0002415"}],"text":"CoVs are 60–140 nm in size and are enveloped (+) ssRNA viruses, which feature an RNA genome, directly available to function as mRNA and thus result in rapid infection. CoVs exhibit RNA genomes of 28–32 kb, comprised of two large overlapping open reading frames (ORFs), which encode the virus replicase (transcriptase) and structural proteins. The SARS-CoV-2 genome is 29,891 bp in size, which encodes 9860 amino acids. The ssRNA are capped and tailed with a 5′-capping structure and 3′-poly A tail at the termini. The genome is the same sense as virus mRNA indicating that the viral RNA is translated through its own (+) RNA to synthesize RNA dependent RNA polymerase (RdRp; PDB: 6M71)."}

{"project":"LitCovid-PubTator","denotations":[{"id":"426","span":{"begin":675,"end":678},"obj":"Gene"},{"id":"427","span":{"begin":0,"end":4},"obj":"Species"},{"id":"428","span":{"begin":49,"end":62},"obj":"Species"},{"id":"429","span":{"begin":168,"end":172},"obj":"Species"},{"id":"430","span":{"begin":347,"end":357},"obj":"Species"},{"id":"431","span":{"begin":456,"end":459},"obj":"Gene"},{"id":"432","span":{"begin":423,"end":428},"obj":"Chemical"},{"id":"433","span":{"begin":157,"end":166},"obj":"Disease"}],"attributes":[{"id":"A426","pred":"tao:has_database_id","subj":"426","obj":"Gene:5131"},{"id":"A427","pred":"tao:has_database_id","subj":"427","obj":"Tax:11118"},{"id":"A428","pred":"tao:has_database_id","subj":"428","obj":"Tax:439488"},{"id":"A429","pred":"tao:has_database_id","subj":"429","obj":"Tax:11118"},{"id":"A430","pred":"tao:has_database_id","subj":"430","obj":"Tax:2697049"},{"id":"A431","pred":"tao:has_database_id","subj":"431","obj":"Gene:28884"},{"id":"A433","pred":"tao:has_database_id","subj":"433","obj":"MESH:D007239"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"CoVs are 60–140 nm in size and are enveloped (+) ssRNA viruses, which feature an RNA genome, directly available to function as mRNA and thus result in rapid infection. CoVs exhibit RNA genomes of 28–32 kb, comprised of two large overlapping open reading frames (ORFs), which encode the virus replicase (transcriptase) and structural proteins. The SARS-CoV-2 genome is 29,891 bp in size, which encodes 9860 amino acids. The ssRNA are capped and tailed with a 5′-capping structure and 3′-poly A tail at the termini. The genome is the same sense as virus mRNA indicating that the viral RNA is translated through its own (+) RNA to synthesize RNA dependent RNA polymerase (RdRp; PDB: 6M71)."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T56","span":{"begin":157,"end":166},"obj":"Disease"},{"id":"T57","span":{"begin":347,"end":355},"obj":"Disease"}],"attributes":[{"id":"A56","pred":"mondo_id","subj":"T56","obj":"http://purl.obolibrary.org/obo/MONDO_0005550"},{"id":"A57","pred":"mondo_id","subj":"T57","obj":"http://purl.obolibrary.org/obo/MONDO_0005091"}],"text":"CoVs are 60–140 nm in size and are enveloped (+) ssRNA viruses, which feature an RNA genome, directly available to function as mRNA and thus result in rapid infection. CoVs exhibit RNA genomes of 28–32 kb, comprised of two large overlapping open reading frames (ORFs), which encode the virus replicase (transcriptase) and structural proteins. The SARS-CoV-2 genome is 29,891 bp in size, which encodes 9860 amino acids. The ssRNA are capped and tailed with a 5′-capping structure and 3′-poly A tail at the termini. The genome is the same sense as virus mRNA indicating that the viral RNA is translated through its own (+) RNA to synthesize RNA dependent RNA polymerase (RdRp; PDB: 6M71)."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T111","span":{"begin":55,"end":62},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T112","span":{"begin":202,"end":204},"obj":"http://purl.obolibrary.org/obo/CLO_0007074"},{"id":"T113","span":{"begin":202,"end":204},"obj":"http://purl.obolibrary.org/obo/CLO_0051988"},{"id":"T114","span":{"begin":286,"end":291},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T115","span":{"begin":444,"end":450},"obj":"http://purl.obolibrary.org/obo/UBERON_0002415"},{"id":"T116","span":{"begin":456,"end":457},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T117","span":{"begin":491,"end":492},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T118","span":{"begin":493,"end":497},"obj":"http://purl.obolibrary.org/obo/UBERON_0002415"},{"id":"T119","span":{"begin":546,"end":551},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"}],"text":"CoVs are 60–140 nm in size and are enveloped (+) ssRNA viruses, which feature an RNA genome, directly available to function as mRNA and thus result in rapid infection. CoVs exhibit RNA genomes of 28–32 kb, comprised of two large overlapping open reading frames (ORFs), which encode the virus replicase (transcriptase) and structural proteins. The SARS-CoV-2 genome is 29,891 bp in size, which encodes 9860 amino acids. The ssRNA are capped and tailed with a 5′-capping structure and 3′-poly A tail at the termini. The genome is the same sense as virus mRNA indicating that the viral RNA is translated through its own (+) RNA to synthesize RNA dependent RNA polymerase (RdRp; PDB: 6M71)."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T259","span":{"begin":333,"end":341},"obj":"Chemical"},{"id":"T260","span":{"begin":406,"end":417},"obj":"Chemical"},{"id":"T261","span":{"begin":406,"end":411},"obj":"Chemical"},{"id":"T262","span":{"begin":412,"end":417},"obj":"Chemical"}],"attributes":[{"id":"A259","pred":"chebi_id","subj":"T259","obj":"http://purl.obolibrary.org/obo/CHEBI_36080"},{"id":"A260","pred":"chebi_id","subj":"T260","obj":"http://purl.obolibrary.org/obo/CHEBI_33709"},{"id":"A261","pred":"chebi_id","subj":"T261","obj":"http://purl.obolibrary.org/obo/CHEBI_46882"},{"id":"A262","pred":"chebi_id","subj":"T262","obj":"http://purl.obolibrary.org/obo/CHEBI_37527"}],"text":"CoVs are 60–140 nm in size and are enveloped (+) ssRNA viruses, which feature an RNA genome, directly available to function as mRNA and thus result in rapid infection. CoVs exhibit RNA genomes of 28–32 kb, comprised of two large overlapping open reading frames (ORFs), which encode the virus replicase (transcriptase) and structural proteins. The SARS-CoV-2 genome is 29,891 bp in size, which encodes 9860 amino acids. The ssRNA are capped and tailed with a 5′-capping structure and 3′-poly A tail at the termini. The genome is the same sense as virus mRNA indicating that the viral RNA is translated through its own (+) RNA to synthesize RNA dependent RNA polymerase (RdRp; PDB: 6M71)."}

{"project":"LitCovid-PD-GO-BP","denotations":[{"id":"T9","span":{"begin":303,"end":316},"obj":"http://purl.obolibrary.org/obo/GO_0003968"},{"id":"T10","span":{"begin":303,"end":316},"obj":"http://purl.obolibrary.org/obo/GO_0003899"}],"text":"CoVs are 60–140 nm in size and are enveloped (+) ssRNA viruses, which feature an RNA genome, directly available to function as mRNA and thus result in rapid infection. CoVs exhibit RNA genomes of 28–32 kb, comprised of two large overlapping open reading frames (ORFs), which encode the virus replicase (transcriptase) and structural proteins. The SARS-CoV-2 genome is 29,891 bp in size, which encodes 9860 amino acids. The ssRNA are capped and tailed with a 5′-capping structure and 3′-poly A tail at the termini. The genome is the same sense as virus mRNA indicating that the viral RNA is translated through its own (+) RNA to synthesize RNA dependent RNA polymerase (RdRp; PDB: 6M71)."}

{"project":"LitCovid-sentences","denotations":[{"id":"T89","span":{"begin":0,"end":167},"obj":"Sentence"},{"id":"T90","span":{"begin":168,"end":342},"obj":"Sentence"},{"id":"T91","span":{"begin":343,"end":418},"obj":"Sentence"},{"id":"T92","span":{"begin":419,"end":513},"obj":"Sentence"},{"id":"T93","span":{"begin":514,"end":679},"obj":"Sentence"},{"id":"T94","span":{"begin":680,"end":686},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"CoVs are 60–140 nm in size and are enveloped (+) ssRNA viruses, which feature an RNA genome, directly available to function as mRNA and thus result in rapid infection. CoVs exhibit RNA genomes of 28–32 kb, comprised of two large overlapping open reading frames (ORFs), which encode the virus replicase (transcriptase) and structural proteins. The SARS-CoV-2 genome is 29,891 bp in size, which encodes 9860 amino acids. The ssRNA are capped and tailed with a 5′-capping structure and 3′-poly A tail at the termini. The genome is the same sense as virus mRNA indicating that the viral RNA is translated through its own (+) RNA to synthesize RNA dependent RNA polymerase (RdRp; PDB: 6M71)."}