PMC:7340597 / 20206-21011 JSONTXT

{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T115","span":{"begin":37,"end":41},"obj":"Body_part"},{"id":"T116","span":{"begin":104,"end":112},"obj":"Body_part"},{"id":"T117","span":{"begin":128,"end":140},"obj":"Body_part"},{"id":"T118","span":{"begin":141,"end":147},"obj":"Body_part"},{"id":"T119","span":{"begin":485,"end":493},"obj":"Body_part"},{"id":"T120","span":{"begin":530,"end":543},"obj":"Body_part"},{"id":"T121","span":{"begin":530,"end":535},"obj":"Body_part"},{"id":"T122","span":{"begin":613,"end":624},"obj":"Body_part"}],"attributes":[{"id":"A115","pred":"fma_id","subj":"T115","obj":"http://purl.org/sig/ont/fma/fma7195"},{"id":"A116","pred":"fma_id","subj":"T116","obj":"http://purl.org/sig/ont/fma/fma264783"},{"id":"A117","pred":"fma_id","subj":"T117","obj":"http://purl.org/sig/ont/fma/fma63877"},{"id":"A118","pred":"fma_id","subj":"T118","obj":"http://purl.org/sig/ont/fma/fma9637"},{"id":"A119","pred":"fma_id","subj":"T119","obj":"http://purl.org/sig/ont/fma/fma264783"},{"id":"A120","pred":"fma_id","subj":"T120","obj":"http://purl.org/sig/ont/fma/fma63183"},{"id":"A121","pred":"fma_id","subj":"T121","obj":"http://purl.org/sig/ont/fma/fma9670"},{"id":"A122","pred":"fma_id","subj":"T122","obj":"http://purl.org/sig/ont/fma/fma62861"}],"text":"Biopsy specimens showed a pattern of lung injury, that was partially identical to that of case 1. Intra-alveolar depositions of fibroblastic tissue were found, consistent with organizing pneumonia. However, a predominant, diffuse component of fibrinous exudate in the alveoli was present, which was not the case in the aforementioned case with organizing pneumonia. Other histologic findings were a chronic inflammatory infiltrate, and mild interstitial changes, including widening of alveolar septa. Microthrombi in small septal blood vessels were also observed. Neither remnants hyaline membranes nor prominent eosinophils were present. Additional PAS-D stain did not show any fungi. The overall histologic pattern of this case was classified as acute fibrinous and organizing pneumonia (AFOP), Fig. 2D."}

{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T69","span":{"begin":37,"end":41},"obj":"Body_part"},{"id":"T70","span":{"begin":141,"end":147},"obj":"Body_part"},{"id":"T71","span":{"begin":253,"end":260},"obj":"Body_part"},{"id":"T72","span":{"begin":530,"end":543},"obj":"Body_part"},{"id":"T73","span":{"begin":530,"end":535},"obj":"Body_part"},{"id":"T74","span":{"begin":536,"end":543},"obj":"Body_part"}],"attributes":[{"id":"A69","pred":"uberon_id","subj":"T69","obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"A70","pred":"uberon_id","subj":"T70","obj":"http://purl.obolibrary.org/obo/UBERON_0000479"},{"id":"A71","pred":"uberon_id","subj":"T71","obj":"http://purl.obolibrary.org/obo/UBERON_0007780"},{"id":"A72","pred":"uberon_id","subj":"T72","obj":"http://purl.obolibrary.org/obo/UBERON_0001981"},{"id":"A73","pred":"uberon_id","subj":"T73","obj":"http://purl.obolibrary.org/obo/UBERON_0000178"},{"id":"A74","pred":"uberon_id","subj":"T74","obj":"http://purl.obolibrary.org/obo/UBERON_0000055"}],"text":"Biopsy specimens showed a pattern of lung injury, that was partially identical to that of case 1. Intra-alveolar depositions of fibroblastic tissue were found, consistent with organizing pneumonia. However, a predominant, diffuse component of fibrinous exudate in the alveoli was present, which was not the case in the aforementioned case with organizing pneumonia. Other histologic findings were a chronic inflammatory infiltrate, and mild interstitial changes, including widening of alveolar septa. Microthrombi in small septal blood vessels were also observed. Neither remnants hyaline membranes nor prominent eosinophils were present. Additional PAS-D stain did not show any fungi. The overall histologic pattern of this case was classified as acute fibrinous and organizing pneumonia (AFOP), Fig. 2D."}

{"project":"LitCovid-PubTator","denotations":[{"id":"466","span":{"begin":37,"end":48},"obj":"Disease"},{"id":"467","span":{"begin":187,"end":196},"obj":"Disease"},{"id":"468","span":{"begin":355,"end":364},"obj":"Disease"},{"id":"469","span":{"begin":779,"end":788},"obj":"Disease"}],"attributes":[{"id":"A466","pred":"tao:has_database_id","subj":"466","obj":"MESH:D055370"},{"id":"A467","pred":"tao:has_database_id","subj":"467","obj":"MESH:D011014"},{"id":"A468","pred":"tao:has_database_id","subj":"468","obj":"MESH:D011014"},{"id":"A469","pred":"tao:has_database_id","subj":"469","obj":"MESH:D011014"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}],"text":"Biopsy specimens showed a pattern of lung injury, that was partially identical to that of case 1. Intra-alveolar depositions of fibroblastic tissue were found, consistent with organizing pneumonia. However, a predominant, diffuse component of fibrinous exudate in the alveoli was present, which was not the case in the aforementioned case with organizing pneumonia. Other histologic findings were a chronic inflammatory infiltrate, and mild interstitial changes, including widening of alveolar septa. Microthrombi in small septal blood vessels were also observed. Neither remnants hyaline membranes nor prominent eosinophils were present. Additional PAS-D stain did not show any fungi. The overall histologic pattern of this case was classified as acute fibrinous and organizing pneumonia (AFOP), Fig. 2D."}

{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T165","span":{"begin":42,"end":48},"obj":"Disease"},{"id":"T166","span":{"begin":176,"end":196},"obj":"Disease"},{"id":"T168","span":{"begin":187,"end":196},"obj":"Disease"},{"id":"T169","span":{"begin":344,"end":364},"obj":"Disease"},{"id":"T171","span":{"begin":355,"end":364},"obj":"Disease"},{"id":"T172","span":{"begin":650,"end":653},"obj":"Disease"},{"id":"T173","span":{"begin":768,"end":788},"obj":"Disease"},{"id":"T175","span":{"begin":779,"end":788},"obj":"Disease"}],"attributes":[{"id":"A165","pred":"mondo_id","subj":"T165","obj":"http://purl.obolibrary.org/obo/MONDO_0021178"},{"id":"A166","pred":"mondo_id","subj":"T166","obj":"http://purl.obolibrary.org/obo/MONDO_0015265"},{"id":"A167","pred":"mondo_id","subj":"T166","obj":"http://purl.obolibrary.org/obo/MONDO_0056821"},{"id":"A168","pred":"mondo_id","subj":"T168","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A169","pred":"mondo_id","subj":"T169","obj":"http://purl.obolibrary.org/obo/MONDO_0015265"},{"id":"A170","pred":"mondo_id","subj":"T169","obj":"http://purl.obolibrary.org/obo/MONDO_0056821"},{"id":"A171","pred":"mondo_id","subj":"T171","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A172","pred":"mondo_id","subj":"T172","obj":"http://purl.obolibrary.org/obo/MONDO_0004277"},{"id":"A173","pred":"mondo_id","subj":"T173","obj":"http://purl.obolibrary.org/obo/MONDO_0015265"},{"id":"A174","pred":"mondo_id","subj":"T173","obj":"http://purl.obolibrary.org/obo/MONDO_0056821"},{"id":"A175","pred":"mondo_id","subj":"T175","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"}],"text":"Biopsy specimens showed a pattern of lung injury, that was partially identical to that of case 1. Intra-alveolar depositions of fibroblastic tissue were found, consistent with organizing pneumonia. However, a predominant, diffuse component of fibrinous exudate in the alveoli was present, which was not the case in the aforementioned case with organizing pneumonia. Other histologic findings were a chronic inflammatory infiltrate, and mild interstitial changes, including widening of alveolar septa. Microthrombi in small septal blood vessels were also observed. Neither remnants hyaline membranes nor prominent eosinophils were present. Additional PAS-D stain did not show any fungi. The overall histologic pattern of this case was classified as acute fibrinous and organizing pneumonia (AFOP), Fig. 2D."}

{"project":"LitCovid-PD-CLO","denotations":[{"id":"T177","span":{"begin":24,"end":25},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T178","span":{"begin":37,"end":41},"obj":"http://purl.obolibrary.org/obo/UBERON_0002048"},{"id":"T179","span":{"begin":37,"end":41},"obj":"http://www.ebi.ac.uk/efo/EFO_0000934"},{"id":"T180","span":{"begin":128,"end":140},"obj":"http://purl.obolibrary.org/obo/CL_0000057"},{"id":"T181","span":{"begin":176,"end":186},"obj":"http://purl.obolibrary.org/obo/OBI_0000245"},{"id":"T182","span":{"begin":207,"end":208},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T183","span":{"begin":344,"end":354},"obj":"http://purl.obolibrary.org/obo/OBI_0000245"},{"id":"T184","span":{"begin":397,"end":398},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T185","span":{"begin":530,"end":543},"obj":"http://purl.obolibrary.org/obo/UBERON_0001981"},{"id":"T186","span":{"begin":530,"end":543},"obj":"http://www.ebi.ac.uk/efo/EFO_0000817"},{"id":"T187","span":{"begin":589,"end":598},"obj":"http://purl.obolibrary.org/obo/UBERON_0000158"},{"id":"T188","span":{"begin":768,"end":778},"obj":"http://purl.obolibrary.org/obo/OBI_0000245"}],"text":"Biopsy specimens showed a pattern of lung injury, that was partially identical to that of case 1. Intra-alveolar depositions of fibroblastic tissue were found, consistent with organizing pneumonia. However, a predominant, diffuse component of fibrinous exudate in the alveoli was present, which was not the case in the aforementioned case with organizing pneumonia. Other histologic findings were a chronic inflammatory infiltrate, and mild interstitial changes, including widening of alveolar septa. Microthrombi in small septal blood vessels were also observed. Neither remnants hyaline membranes nor prominent eosinophils were present. Additional PAS-D stain did not show any fungi. The overall histologic pattern of this case was classified as acute fibrinous and organizing pneumonia (AFOP), Fig. 2D."}

{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T109","span":{"begin":650,"end":653},"obj":"Chemical"}],"attributes":[{"id":"A109","pred":"chebi_id","subj":"T109","obj":"http://purl.obolibrary.org/obo/CHEBI_27565"}],"text":"Biopsy specimens showed a pattern of lung injury, that was partially identical to that of case 1. Intra-alveolar depositions of fibroblastic tissue were found, consistent with organizing pneumonia. However, a predominant, diffuse component of fibrinous exudate in the alveoli was present, which was not the case in the aforementioned case with organizing pneumonia. Other histologic findings were a chronic inflammatory infiltrate, and mild interstitial changes, including widening of alveolar septa. Microthrombi in small septal blood vessels were also observed. Neither remnants hyaline membranes nor prominent eosinophils were present. Additional PAS-D stain did not show any fungi. The overall histologic pattern of this case was classified as acute fibrinous and organizing pneumonia (AFOP), Fig. 2D."}

{"project":"LitCovid-PD-HP","denotations":[{"id":"T52","span":{"begin":187,"end":196},"obj":"Phenotype"},{"id":"T53","span":{"begin":355,"end":364},"obj":"Phenotype"},{"id":"T54","span":{"begin":779,"end":788},"obj":"Phenotype"}],"attributes":[{"id":"A52","pred":"hp_id","subj":"T52","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A53","pred":"hp_id","subj":"T53","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A54","pred":"hp_id","subj":"T54","obj":"http://purl.obolibrary.org/obo/HP_0002090"}],"text":"Biopsy specimens showed a pattern of lung injury, that was partially identical to that of case 1. Intra-alveolar depositions of fibroblastic tissue were found, consistent with organizing pneumonia. However, a predominant, diffuse component of fibrinous exudate in the alveoli was present, which was not the case in the aforementioned case with organizing pneumonia. Other histologic findings were a chronic inflammatory infiltrate, and mild interstitial changes, including widening of alveolar septa. Microthrombi in small septal blood vessels were also observed. Neither remnants hyaline membranes nor prominent eosinophils were present. Additional PAS-D stain did not show any fungi. The overall histologic pattern of this case was classified as acute fibrinous and organizing pneumonia (AFOP), Fig. 2D."}

{"project":"LitCovid-sentences","denotations":[{"id":"T172","span":{"begin":0,"end":97},"obj":"Sentence"},{"id":"T173","span":{"begin":98,"end":197},"obj":"Sentence"},{"id":"T174","span":{"begin":198,"end":365},"obj":"Sentence"},{"id":"T175","span":{"begin":366,"end":500},"obj":"Sentence"},{"id":"T176","span":{"begin":501,"end":563},"obj":"Sentence"},{"id":"T177","span":{"begin":564,"end":638},"obj":"Sentence"},{"id":"T178","span":{"begin":639,"end":685},"obj":"Sentence"},{"id":"T179","span":{"begin":686,"end":805},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"text":"Biopsy specimens showed a pattern of lung injury, that was partially identical to that of case 1. Intra-alveolar depositions of fibroblastic tissue were found, consistent with organizing pneumonia. However, a predominant, diffuse component of fibrinous exudate in the alveoli was present, which was not the case in the aforementioned case with organizing pneumonia. Other histologic findings were a chronic inflammatory infiltrate, and mild interstitial changes, including widening of alveolar septa. Microthrombi in small septal blood vessels were also observed. Neither remnants hyaline membranes nor prominent eosinophils were present. Additional PAS-D stain did not show any fungi. The overall histologic pattern of this case was classified as acute fibrinous and organizing pneumonia (AFOP), Fig. 2D."}

{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T28835","span":{"begin":37,"end":41},"obj":"UBERON:0002048"},{"id":"T46508","span":{"begin":104,"end":112},"obj":"UBERON:0003215"},{"id":"T32950","span":{"begin":128,"end":140},"obj":"CL:0000057"},{"id":"T85905","span":{"begin":141,"end":147},"obj":"UBERON:0000479"},{"id":"T72453","span":{"begin":268,"end":275},"obj":"UBERON:0003215"},{"id":"T83892","span":{"begin":441,"end":453},"obj":"UBERON:0005169"},{"id":"T50871","span":{"begin":485,"end":493},"obj":"UBERON:0003215"},{"id":"T65185","span":{"begin":494,"end":499},"obj":"UBERON:0003037"},{"id":"T3448","span":{"begin":523,"end":529},"obj":"UBERON:0003037"},{"id":"T58151","span":{"begin":530,"end":543},"obj":"UBERON:0001981"},{"id":"T66331","span":{"begin":589,"end":598},"obj":"GO:0016020"},{"id":"T96825","span":{"begin":613,"end":624},"obj":"CL:0000771"},{"id":"T62230","span":{"begin":679,"end":684},"obj":"NCBITaxon:4751"}],"text":"Biopsy specimens showed a pattern of lung injury, that was partially identical to that of case 1. Intra-alveolar depositions of fibroblastic tissue were found, consistent with organizing pneumonia. However, a predominant, diffuse component of fibrinous exudate in the alveoli was present, which was not the case in the aforementioned case with organizing pneumonia. Other histologic findings were a chronic inflammatory infiltrate, and mild interstitial changes, including widening of alveolar septa. Microthrombi in small septal blood vessels were also observed. Neither remnants hyaline membranes nor prominent eosinophils were present. Additional PAS-D stain did not show any fungi. The overall histologic pattern of this case was classified as acute fibrinous and organizing pneumonia (AFOP), Fig. 2D."}