PMC:7301188 / 3533-4837 JSONTXT

{"target":"https://pubannotation.org/docs/sourcedb/PMC/sourceid/7301188","sourcedb":"PMC","sourceid":"7301188","source_url":"https://www.ncbi.nlm.nih.gov/pmc/7301188","text":"2.2. Clinical Classifications\n\n2.2.1. Case Identification\nAccording to the Guidance for Corona Virus Disease 2019: Prevention, Control, Diagnosis, and Management edited by the National Health Commission of the People's Republic of China, all cases were identified into four categories of mild cases, ordinary cases, severe cases, and critical cases. (1) Mild cases had mild clinical symptoms and no pneumonia manifestation in imaging. (2) Ordinary cases had symptoms like fever and respiratory tract symptoms, and pneumonia manifestation can be seen in imaging. (3) Severe cases met any of the following: respiratory distress, RR ≥ 30 breaths/min; the oxygen saturation is less than 93% at a rest state; or arterial partial pressure of oxygen (PaO2)/oxygen concentration (FiO2) ≤ 300 mmHg (1 mmHg = 0.133 kPa). Patients with \u003e50% lesion progression within 24 to 48 hours in pulmonary imaging were treated as severe cases. (4) Critical cases met any of the following: respiratory failure occurs, and mechanical ventilation is required; shock occurs; or complicated with other organ failure that requires monitoring and treatment in ICU.\n\n2.2.2. Outcome of Illness\nAccording to clinical progression, outcomes in endpoints were divided into four types: hospital discharge, improved, exacerbation, and death.","divisions":[{"label":"title","span":{"begin":0,"end":29}},{"label":"sec","span":{"begin":31,"end":1135}},{"label":"title","span":{"begin":31,"end":57}},{"label":"p","span":{"begin":58,"end":1135}},{"label":"title","span":{"begin":1137,"end":1162}}],"tracks":[{"project":"LitCovid-PMC-OGER-BB","denotations":[{"id":"T30","span":{"begin":88,"end":94},"obj":"NCBITaxon:859912"},{"id":"T31","span":{"begin":399,"end":408},"obj":"UBERON:0002048"},{"id":"T32","span":{"begin":482,"end":499},"obj":"UBERON:0000065"},{"id":"T33","span":{"begin":514,"end":523},"obj":"UBERON:0002048"},{"id":"T34","span":{"begin":605,"end":616},"obj":"UBERON:0001004"},{"id":"T35","span":{"begin":707,"end":715},"obj":"UBERON:0001637"},{"id":"T36","span":{"begin":874,"end":883},"obj":"UBERON:0002048"},{"id":"T37","span":{"begin":967,"end":978},"obj":"UBERON:0001004"},{"id":"T38","span":{"begin":1075,"end":1080},"obj":"UBERON:0000062"},{"id":"T39","span":{"begin":1298,"end":1303},"obj":"GO:0016265"},{"id":"T55122","span":{"begin":88,"end":94},"obj":"NCBITaxon:859912"},{"id":"T25183","span":{"begin":399,"end":408},"obj":"UBERON:0002048"},{"id":"T28285","span":{"begin":482,"end":499},"obj":"UBERON:0000065"},{"id":"T87513","span":{"begin":514,"end":523},"obj":"UBERON:0002048"},{"id":"T92813","span":{"begin":605,"end":616},"obj":"UBERON:0001004"},{"id":"T4800","span":{"begin":707,"end":715},"obj":"UBERON:0001637"},{"id":"T31469","span":{"begin":874,"end":883},"obj":"UBERON:0002048"},{"id":"T70684","span":{"begin":967,"end":978},"obj":"UBERON:0001004"},{"id":"T87749","span":{"begin":1075,"end":1080},"obj":"UBERON:0000062"},{"id":"T90276","span":{"begin":1298,"end":1303},"obj":"GO:0016265"}],"attributes":[{"subj":"T30","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T31","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T32","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T33","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T34","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T35","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T36","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T37","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T38","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T39","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T55122","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T25183","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T28285","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T87513","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T92813","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T4800","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T31469","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T70684","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T87749","pred":"source","obj":"LitCovid-PMC-OGER-BB"},{"subj":"T90276","pred":"source","obj":"LitCovid-PMC-OGER-BB"}]},{"project":"LitCovid-PD-FMA-UBERON","denotations":[{"id":"T4","span":{"begin":482,"end":499},"obj":"Body_part"},{"id":"T5","span":{"begin":1075,"end":1080},"obj":"Body_part"}],"attributes":[{"id":"A4","pred":"fma_id","subj":"T4","obj":"http://purl.org/sig/ont/fma/fma265130"},{"id":"A5","pred":"fma_id","subj":"T5","obj":"http://purl.org/sig/ont/fma/fma67498"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-FMA-UBERON"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-FMA-UBERON"}]},{"project":"LitCovid-PD-UBERON","denotations":[{"id":"T3","span":{"begin":482,"end":499},"obj":"Body_part"},{"id":"T4","span":{"begin":1075,"end":1080},"obj":"Body_part"}],"attributes":[{"id":"A3","pred":"uberon_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/UBERON_0000065"},{"id":"A4","pred":"uberon_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/UBERON_0000062"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-UBERON"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-UBERON"}]},{"project":"LitCovid-PubTator","denotations":[{"id":"106","span":{"begin":210,"end":216},"obj":"Species"},{"id":"107","span":{"begin":811,"end":819},"obj":"Species"},{"id":"108","span":{"begin":652,"end":658},"obj":"Chemical"},{"id":"109","span":{"begin":736,"end":742},"obj":"Chemical"},{"id":"110","span":{"begin":750,"end":756},"obj":"Chemical"},{"id":"111","span":{"begin":772,"end":776},"obj":"Chemical"},{"id":"112","span":{"begin":88,"end":113},"obj":"Disease"},{"id":"113","span":{"begin":399,"end":408},"obj":"Disease"},{"id":"114","span":{"begin":472,"end":477},"obj":"Disease"},{"id":"115","span":{"begin":482,"end":508},"obj":"Disease"},{"id":"116","span":{"begin":514,"end":523},"obj":"Disease"},{"id":"117","span":{"begin":605,"end":625},"obj":"Disease"},{"id":"118","span":{"begin":967,"end":986},"obj":"Disease"},{"id":"119","span":{"begin":1075,"end":1088},"obj":"Disease"},{"id":"121","span":{"begin":1155,"end":1162},"obj":"Disease"},{"id":"123","span":{"begin":1298,"end":1303},"obj":"Disease"}],"attributes":[{"id":"A106","pred":"tao:has_database_id","subj":"106","obj":"Tax:9606"},{"id":"A107","pred":"tao:has_database_id","subj":"107","obj":"Tax:9606"},{"id":"A108","pred":"tao:has_database_id","subj":"108","obj":"MESH:D010100"},{"id":"A109","pred":"tao:has_database_id","subj":"109","obj":"MESH:D010100"},{"id":"A110","pred":"tao:has_database_id","subj":"110","obj":"MESH:D010100"},{"id":"A112","pred":"tao:has_database_id","subj":"112","obj":"MESH:C000657245"},{"id":"A113","pred":"tao:has_database_id","subj":"113","obj":"MESH:D011014"},{"id":"A114","pred":"tao:has_database_id","subj":"114","obj":"MESH:D005334"},{"id":"A115","pred":"tao:has_database_id","subj":"115","obj":"MESH:D012140"},{"id":"A116","pred":"tao:has_database_id","subj":"116","obj":"MESH:D011014"},{"id":"A117","pred":"tao:has_database_id","subj":"117","obj":"MESH:D012128"},{"id":"A118","pred":"tao:has_database_id","subj":"118","obj":"MESH:D012131"},{"id":"A119","pred":"tao:has_database_id","subj":"119","obj":"MESH:D009102"},{"id":"A121","pred":"tao:has_database_id","subj":"121","obj":"MESH:D002908"},{"id":"A123","pred":"tao:has_database_id","subj":"123","obj":"MESH:D003643"},{"subj":"106","pred":"source","obj":"LitCovid-PubTator"},{"subj":"107","pred":"source","obj":"LitCovid-PubTator"},{"subj":"108","pred":"source","obj":"LitCovid-PubTator"},{"subj":"109","pred":"source","obj":"LitCovid-PubTator"},{"subj":"110","pred":"source","obj":"LitCovid-PubTator"},{"subj":"111","pred":"source","obj":"LitCovid-PubTator"},{"subj":"112","pred":"source","obj":"LitCovid-PubTator"},{"subj":"113","pred":"source","obj":"LitCovid-PubTator"},{"subj":"114","pred":"source","obj":"LitCovid-PubTator"},{"subj":"115","pred":"source","obj":"LitCovid-PubTator"},{"subj":"116","pred":"source","obj":"LitCovid-PubTator"},{"subj":"117","pred":"source","obj":"LitCovid-PubTator"},{"subj":"118","pred":"source","obj":"LitCovid-PubTator"},{"subj":"119","pred":"source","obj":"LitCovid-PubTator"},{"subj":"121","pred":"source","obj":"LitCovid-PubTator"},{"subj":"123","pred":"source","obj":"LitCovid-PubTator"}],"namespaces":[{"prefix":"Tax","uri":"https://www.ncbi.nlm.nih.gov/taxonomy/"},{"prefix":"MESH","uri":"https://id.nlm.nih.gov/mesh/"},{"prefix":"Gene","uri":"https://www.ncbi.nlm.nih.gov/gene/"},{"prefix":"CVCL","uri":"https://web.expasy.org/cellosaurus/CVCL_"}]},{"project":"LitCovid-PD-MONDO","denotations":[{"id":"T41","span":{"begin":88,"end":113},"obj":"Disease"},{"id":"T42","span":{"begin":399,"end":408},"obj":"Disease"},{"id":"T43","span":{"begin":514,"end":523},"obj":"Disease"},{"id":"T44","span":{"begin":967,"end":986},"obj":"Disease"}],"attributes":[{"id":"A41","pred":"mondo_id","subj":"T41","obj":"http://purl.obolibrary.org/obo/MONDO_0100096"},{"id":"A42","pred":"mondo_id","subj":"T42","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A43","pred":"mondo_id","subj":"T43","obj":"http://purl.obolibrary.org/obo/MONDO_0005249"},{"id":"A44","pred":"mondo_id","subj":"T44","obj":"http://purl.obolibrary.org/obo/MONDO_0021113"},{"subj":"T41","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T42","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T43","pred":"source","obj":"LitCovid-PD-MONDO"},{"subj":"T44","pred":"source","obj":"LitCovid-PD-MONDO"}]},{"project":"LitCovid-PD-CLO","denotations":[{"id":"T37","span":{"begin":95,"end":100},"obj":"http://purl.obolibrary.org/obo/NCBITaxon_10239"},{"id":"T38","span":{"begin":690,"end":691},"obj":"http://purl.obolibrary.org/obo/CLO_0001020"},{"id":"T39","span":{"begin":707,"end":715},"obj":"http://purl.obolibrary.org/obo/UBERON_0001637"},{"id":"T40","span":{"begin":707,"end":715},"obj":"http://www.ebi.ac.uk/efo/EFO_0000814"},{"id":"T41","span":{"begin":862,"end":864},"obj":"http://purl.obolibrary.org/obo/CLO_0001382"},{"id":"T42","span":{"begin":1075,"end":1080},"obj":"http://purl.obolibrary.org/obo/UBERON_0003103"}],"attributes":[{"subj":"T37","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T38","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T39","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T40","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T41","pred":"source","obj":"LitCovid-PD-CLO"},{"subj":"T42","pred":"source","obj":"LitCovid-PD-CLO"}]},{"project":"LitCovid-PD-CHEBI","denotations":[{"id":"T25","span":{"begin":627,"end":629},"obj":"Chemical"},{"id":"T26","span":{"begin":652,"end":658},"obj":"Chemical"},{"id":"T27","span":{"begin":736,"end":742},"obj":"Chemical"},{"id":"T28","span":{"begin":750,"end":756},"obj":"Chemical"}],"attributes":[{"id":"A25","pred":"chebi_id","subj":"T25","obj":"http://purl.obolibrary.org/obo/CHEBI_73811"},{"id":"A26","pred":"chebi_id","subj":"T26","obj":"http://purl.obolibrary.org/obo/CHEBI_25805"},{"id":"A27","pred":"chebi_id","subj":"T27","obj":"http://purl.obolibrary.org/obo/CHEBI_25805"},{"id":"A28","pred":"chebi_id","subj":"T28","obj":"http://purl.obolibrary.org/obo/CHEBI_25805"},{"subj":"T25","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T26","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T27","pred":"source","obj":"LitCovid-PD-CHEBI"},{"subj":"T28","pred":"source","obj":"LitCovid-PD-CHEBI"}]},{"project":"LitCovid-sentences","denotations":[{"id":"T37","span":{"begin":0,"end":4},"obj":"Sentence"},{"id":"T38","span":{"begin":5,"end":29},"obj":"Sentence"},{"id":"T39","span":{"begin":31,"end":37},"obj":"Sentence"},{"id":"T40","span":{"begin":38,"end":57},"obj":"Sentence"},{"id":"T41","span":{"begin":58,"end":114},"obj":"Sentence"},{"id":"T42","span":{"begin":115,"end":810},"obj":"Sentence"},{"id":"T43","span":{"begin":811,"end":1135},"obj":"Sentence"},{"id":"T44","span":{"begin":1137,"end":1143},"obj":"Sentence"},{"id":"T45","span":{"begin":1144,"end":1162},"obj":"Sentence"},{"id":"T46","span":{"begin":1163,"end":1304},"obj":"Sentence"}],"namespaces":[{"prefix":"_base","uri":"http://pubannotation.org/ontology/tao.owl#"}],"attributes":[{"subj":"T37","pred":"source","obj":"LitCovid-sentences"},{"subj":"T38","pred":"source","obj":"LitCovid-sentences"},{"subj":"T39","pred":"source","obj":"LitCovid-sentences"},{"subj":"T40","pred":"source","obj":"LitCovid-sentences"},{"subj":"T41","pred":"source","obj":"LitCovid-sentences"},{"subj":"T42","pred":"source","obj":"LitCovid-sentences"},{"subj":"T43","pred":"source","obj":"LitCovid-sentences"},{"subj":"T44","pred":"source","obj":"LitCovid-sentences"},{"subj":"T45","pred":"source","obj":"LitCovid-sentences"},{"subj":"T46","pred":"source","obj":"LitCovid-sentences"}]},{"project":"LitCovid-PD-HP","denotations":[{"id":"T3","span":{"begin":399,"end":408},"obj":"Phenotype"},{"id":"T4","span":{"begin":472,"end":477},"obj":"Phenotype"},{"id":"T5","span":{"begin":514,"end":523},"obj":"Phenotype"},{"id":"T6","span":{"begin":605,"end":625},"obj":"Phenotype"},{"id":"T7","span":{"begin":967,"end":986},"obj":"Phenotype"},{"id":"T8","span":{"begin":1035,"end":1040},"obj":"Phenotype"}],"attributes":[{"id":"A3","pred":"hp_id","subj":"T3","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A4","pred":"hp_id","subj":"T4","obj":"http://purl.obolibrary.org/obo/HP_0001945"},{"id":"A5","pred":"hp_id","subj":"T5","obj":"http://purl.obolibrary.org/obo/HP_0002090"},{"id":"A6","pred":"hp_id","subj":"T6","obj":"http://purl.obolibrary.org/obo/HP_0002098"},{"id":"A7","pred":"hp_id","subj":"T7","obj":"http://purl.obolibrary.org/obo/HP_0002878"},{"id":"A8","pred":"hp_id","subj":"T8","obj":"http://purl.obolibrary.org/obo/HP_0031273"},{"subj":"T3","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T4","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T5","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T6","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T7","pred":"source","obj":"LitCovid-PD-HP"},{"subj":"T8","pred":"source","obj":"LitCovid-PD-HP"}]}],"config":{"attribute types":[{"pred":"source","value type":"selection","values":[{"id":"LitCovid-PMC-OGER-BB","color":"#eca693","default":true},{"id":"LitCovid-PD-FMA-UBERON","color":"#9399ec"},{"id":"LitCovid-PD-UBERON","color":"#b3ec93"},{"id":"LitCovid-PubTator","color":"#ec93cd"},{"id":"LitCovid-PD-MONDO","color":"#93e7ec"},{"id":"LitCovid-PD-CLO","color":"#ecd693"},{"id":"LitCovid-PD-CHEBI","color":"#bc93ec"},{"id":"LitCovid-sentences","color":"#93eca2"},{"id":"LitCovid-PD-HP","color":"#ec939d"}]}]}}